Sonic hedgehog is a potent chemoattractant for human monocytes: Diabetes mellitus inhibits Sonic hedgehog-induced monocyte chemotaxis

Basic Research in Cardiology

Volumn 105, Issue 1, 2010, Pages 61-71

  Dunaeva, Marina ^a   Voo, Stefan ^a   Van Oosterhoud, Carolien ^a   Waltenberger, Johannes ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Atherosclerosis; Chemotaxis; Hedgehog; Monocytes; Signal transduction

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PROTEIN PATCHED; SONIC HEDGEHOG PROTEIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CARDIOVASCULAR RISK; CELL MIGRATION; CELL STIMULATION; CHEMOTAXIS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; FEMALE; GENE ACTIVATION; HEART MUSCLE; HUMAN; HUMAN CELL; MACROPHAGE; MALE; MONOCYTE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AGED; ATHEROSCLEROSIS; CHEMOTAXIS, LEUKOCYTE; CORONARY ARTERY DISEASE; DIABETES MELLITUS, TYPE 2; FEMALE; GTP-BINDING PROTEINS; HEDGEHOG PROTEINS; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; MONOCYTES; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 72449209673     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-009-0047-x     Document Type: Article

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