-
1
-
-
0032404092
-
A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
-
Allikmets R, Schriml LM, Hutchinson A, Romano-Spica V, and Dean M (1998) A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res 58:5337-5339.
-
(1998)
Cancer Res
, vol.58
, pp. 5337-5339
-
-
Allikmets, R.1
Schriml, L.M.2
Hutchinson, A.3
Romano-Spica, V.4
Dean, M.5
-
2
-
-
0142184334
-
Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking
-
Bogan JS, Hendon N, McKee AE, Tsao TS, and Lodish HF (2003) Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking. Nature (Lond) 425:727-733.
-
(2003)
Nature (Lond)
, vol.425
, pp. 727-733
-
-
Bogan, J.S.1
Hendon, N.2
McKee, A.E.3
Tsao, T.S.4
Lodish, H.F.5
-
3
-
-
0035499454
-
Ten years of protein kinase B signalling: A hard Akt to follow
-
Brazil DP and Hemmings BA (2001) Ten years of protein kinase B signalling: a hard Akt to follow. Trends Biochem Sci 26:657-664.
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
4
-
-
0035448879
-
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene
-
Chen WS, Xu PZ, Gottlob K, Chen ML, Sokol K, Shiyanova T, Roninson I, Weng W, Suzuki R, Tobe K, et al. (2001) Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene. Genes Dev 15:2203-2208.
-
(2001)
Genes Dev
, vol.15
, pp. 2203-2208
-
-
Chen, W.S.1
Xu, P.Z.2
Gottlob, K.3
Chen, M.L.4
Sokol, K.5
Shiyanova, T.6
Roninson, I.7
Weng, W.8
Suzuki, R.9
Tobe, K.10
-
5
-
-
0035368548
-
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)
-
Cho H, Mu J, Kim JK, Thorvaldsen JL, Chu Q, Crenshaw EB 3rd, Kaestner KH, Bartolomei MS, Shulman GI, and Birnbaum MJ (2001a) Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science (Wash DC) 292:1728-1731.
-
(2001)
Science (Wash DC)
, vol.292
, pp. 1728-1731
-
-
Cho, H.1
Mu, J.2
Kim, J.K.3
Thorvaldsen, J.L.4
Chu, Q.5
Crenshaw III, E.B.6
Kaestner, K.H.7
Bartolomei, M.S.8
Shulman, G.I.9
Birnbaum, M.J.10
-
6
-
-
0035914388
-
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
-
Cho H, Thorvaldsen JL, Chu Q, Feng F, and Birnbaum MJ (2001b) Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem 276:38349-38352.
-
(2001)
J Biol Chem
, vol.276
, pp. 38349-38352
-
-
Cho, H.1
Thorvaldsen, J.L.2
Chu, Q.3
Feng, F.4
Birnbaum, M.J.5
-
7
-
-
0345688604
-
Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2)
-
Doyle LA and Ross DD (2003) Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2). Oncogene 22:7340-7358.
-
(2003)
Oncogene
, vol.22
, pp. 7340-7358
-
-
Doyle, L.A.1
Ross, D.D.2
-
8
-
-
13044249156
-
A multidrug resistance transporter from human MCF-7 breast cancer cells
-
Doyle LA, Yang W, Abruzzo LV, Krogmann T, Gao Y, Rishi AK, and Ross DD (1998) A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc Natl Acad Sci USA 95:15665-15670.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15665-15670
-
-
Doyle, L.A.1
Yang, W.2
Abruzzo, L.V.3
Krogmann, T.4
Gao, Y.5
Rishi, A.K.6
Ross, D.D.7
-
9
-
-
0042432037
-
Angiotensin II stimulates NHE3 activity by exocytic insertion of the transporter: Role of PI 3-kinase
-
du Cheyron D, Chalumeau C, Defontaine N, Klein C, Kellermann O, Paillard M, and Poggioli J (2003) Angiotensin II stimulates NHE3 activity by exocytic insertion of the transporter: role of PI 3-kinase. Kidney Int 64:939-949.
-
(2003)
Kidney Int
, vol.64
, pp. 939-949
-
-
Du Cheyron, D.1
Chalumeau, C.2
Defontaine, N.3
Klein, C.4
Kellermann, O.5
Paillard, M.6
Poggioli, J.7
-
10
-
-
0035863314
-
The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux
-
Erlichman C, Boerner SA, Hallgren CG, Spieker R, Wang XY, James CD, Scheffer GL, Maliepaard M, Ross DD, Bible KC, et al. (2001) The HER tyrosine kinase inhibitor CI1033 enhances cytotoxicity of 7-ethyl-10-hydroxycamptothecin and topotecan by inhibiting breast cancer resistance protein-mediated drug efflux. Cancer Res 61:739-748.
-
(2001)
Cancer Res
, vol.61
, pp. 739-748
-
-
Erlichman, C.1
Boerner, S.A.2
Hallgren, C.G.3
Spieker, R.4
Wang, X.Y.5
James, C.D.6
Scheffer, G.L.7
Maliepaard, M.8
Ross, D.D.9
Bible, K.C.10
-
11
-
-
0035941297
-
Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B
-
Foster LJ, Li D, Randhawa VK, and Klip A (2001) Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B. J Biol Chem 276:44212-44221.
-
(2001)
J Biol Chem
, vol.276
, pp. 44212-44221
-
-
Foster, L.J.1
Li, D.2
Randhawa, V.K.3
Klip, A.4
-
12
-
-
85047693348
-
Severe diabetes, age-dependent loss of adipose tissue and mild growth deficiency in mice lacking Akt2/PKB beta
-
Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, Coskran T, Black SC, Brees DJ, Wicks JR, et al. (2003) Severe diabetes, age-dependent loss of adipose tissue and mild growth deficiency in mice lacking Akt2/PKB beta. J Clin Investig 112:197-208.
-
(2003)
J Clin Investig
, vol.112
, pp. 197-208
-
-
Garofalo, R.S.1
Orena, S.J.2
Rafidi, K.3
Torchia, A.J.4
Stock, J.L.5
Hildebrandt, A.L.6
Coskran, T.7
Black, S.C.8
Brees, D.J.9
Wicks, J.R.10
-
13
-
-
0042566203
-
The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells
-
Higuchi M, Onishi K, Masuyama N, and Gotoh Y (2003) The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes Cells 8:657-669.
-
(2003)
Genes Cells
, vol.8
, pp. 657-669
-
-
Higuchi, M.1
Onishi, K.2
Masuyama, N.3
Gotoh, Y.4
-
14
-
-
0042856460
-
Breast cancer resistance protein exports sulfated estrogens but not free estrogens
-
Imai Y, Asada S, Tsukahara S, Ishikawa E, Tsuruo T, and Sugimoto Y (2003) Breast cancer resistance protein exports sulfated estrogens but not free estrogens. Mol Pharmacol 64:610-618.
-
(2003)
Mol Pharmacol
, vol.64
, pp. 610-618
-
-
Imai, Y.1
Asada, S.2
Tsukahara, S.3
Ishikawa, E.4
Tsuruo, T.5
Sugimoto, Y.6
-
15
-
-
0034677953
-
Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinase
-
Janecki AJ, Janecki M, Akhter S, and Donowitz M (2000) Basic fibroblast growth factor stimulates surface expression and activity of Na(+)/H(+) exchanger NHE3 via mechanism involving phosphatidylinositol 3-kinase. J Biol Chem 275:8133-8142.
-
(2000)
J Biol Chem
, vol.275
, pp. 8133-8142
-
-
Janecki, A.J.1
Janecki, M.2
Akhter, S.3
Donowitz, M.4
-
16
-
-
0037180446
-
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
-
Jonker JW, Buitelaar M, Wagenaar E, Van Der Valk MA, Scheffer GL, Scheper RJ, Plosch T, Kuipers F, Elferink RP, et al. (2002) The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci USA 99:15649-15654.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15649-15654
-
-
Jonker, J.W.1
Buitelaar, M.2
Wagenaar, E.3
Van Der Valk, M.A.4
Scheffer, G.L.5
Scheper, R.J.6
Plosch, T.7
Kuipers, F.8
Elferink, R.P.9
-
17
-
-
0037050736
-
Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization
-
Kage K, Tsukahara S, Sugiyama T, Asada S, Ishikawa E, Tsuruo T, and Sugimoto Y (2002) Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization. Int J Cancer 97:626-630.
-
(2002)
Int J Cancer
, vol.97
, pp. 626-630
-
-
Kage, K.1
Tsukahara, S.2
Sugiyama, T.3
Asada, S.4
Ishikawa, E.5
Tsuruo, T.6
Sugimoto, Y.7
-
18
-
-
0742288016
-
GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes
-
Karylowski O, Zeigerer A, Cohen A, and McGraw TE (2003) GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes. Mol Biol Cell 15:870-882.
-
(2003)
Mol Biol Cell
, vol.15
, pp. 870-882
-
-
Karylowski, O.1
Zeigerer, A.2
Cohen, A.3
McGraw, T.E.4
-
19
-
-
0036197909
-
Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells
-
Klein RD and Fischer SM (2002) Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. Carcinogenesis 23:217-221.
-
(2002)
Carcinogenesis
, vol.23
, pp. 217-221
-
-
Klein, R.D.1
Fischer, S.M.2
-
20
-
-
0035903178
-
Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3
-
Lee-Kwon W, Johns DC, Cha B, Cavet M, Park J, Tsichlis P, and Donowitz M (2001) Constitutively active phosphatidylinositol 3-kinase and AKT are sufficient to stimulate the epithelial Na+/H+ exchanger 3. J Biol Chem 276:31296-31304.
-
(2001)
J Biol Chem
, vol.276
, pp. 31296-31304
-
-
Lee-Kwon, W.1
Johns, D.C.2
Cha, B.3
Cavet, M.4
Park, J.5
Tsichlis, P.6
Donowitz, M.7
-
21
-
-
0035980060
-
Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis
-
Masuyama N, Oishi K, Mori Y, Ueno T, Takahama Y, and Gotoh Y (2001) Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis. J Biol Chem 276:32799-32805.
-
(2001)
J Biol Chem
, vol.276
, pp. 32799-32805
-
-
Masuyama, N.1
Oishi, K.2
Mori, Y.3
Ueno, T.4
Takahama, Y.5
Gotoh, Y.6
-
22
-
-
0032895533
-
Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes
-
Miyake K, Mickley L, Litman T, Zhan Z, Robey R, Cristensen B, Brangi M, Greenberger L, Dean M, Fojo T, et al. (1999) Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Res 59:8-13.
-
(1999)
Cancer Res
, vol.59
, pp. 8-13
-
-
Miyake, K.1
Mickley, L.2
Litman, T.3
Zhan, Z.4
Robey, R.5
Cristensen, B.6
Brangi, M.7
Greenberger, L.8
Dean, M.9
Fojo, T.10
-
23
-
-
0141866694
-
Akt signaling regulates side population cell phenotype via Bcrp1 translocation
-
Mogi M, Yang J, Lambert JF, Colvin GA, Shiojima I, Skurk C, Summer R, Fine A, Quesenberry PJ, and Walsh K (2003) Akt signaling regulates side population cell phenotype via Bcrp1 translocation. J Biol Chem 278:39068-39075.
-
(2003)
J Biol Chem
, vol.278
, pp. 39068-39075
-
-
Mogi, M.1
Yang, J.2
Lambert, J.F.3
Colvin, G.A.4
Shiojima, I.5
Skurk, C.6
Summer, R.7
Fine, A.8
Quesenberry, P.J.9
Walsh, K.10
-
24
-
-
17544372167
-
Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver
-
Paulusma CC, Kothe MJ, Bakker CT, Bosma PJ, van Bokhoven I, van Marle J, Bolder U, Tytgat GN, and Oude Elferink RP (2000) Zonal down-regulation and redistribution of the multidrug resistance protein 2 during bile duct ligation in rat liver. Hepatology 31:684-693.
-
(2000)
Hepatology
, vol.31
, pp. 684-693
-
-
Paulusma, C.C.1
Kothe, M.J.2
Bakker, C.T.3
Bosma, P.J.4
Van Bokhoven, I.5
Van Marle, J.6
Bolder, U.7
Tytgat, G.N.8
Oude Elferink, R.P.9
-
25
-
-
0038624395
-
Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development and impeded adipogenesis in mice lacking Akt1 and Akt2
-
Peng XD, Xu PZ, Chen ML, Hahn-Windgassen A, Skeen J, Jacobs J, Sundararajan D, Chen WS, Crawford SE, Coleman KG, et al. (2003) Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development and impeded adipogenesis in mice lacking Akt1 and Akt2. Genes Dev 17:1352-1365.
-
(2003)
Genes Dev
, vol.17
, pp. 1352-1365
-
-
Peng, X.D.1
Xu, P.Z.2
Chen, M.L.3
Hahn-Windgassen, A.4
Skeen, J.5
Jacobs, J.6
Sundararajan, D.7
Chen, W.S.8
Crawford, S.E.9
Coleman, K.G.10
-
26
-
-
0036468923
-
Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation and transformed phenotype of breast cancer cells
-
Pianetti S, Guo S, Kavanagh KT, and Sonenshein GE (2002) Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation and transformed phenotype of breast cancer cells. Cancer Res 62:652-655.
-
(2002)
Cancer Res
, vol.62
, pp. 652-655
-
-
Pianetti, S.1
Guo, S.2
Kavanagh, K.T.3
Sonenshein, G.E.4
-
27
-
-
0034728768
-
The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
-
Rocchi E, Khodjakov A, Volk EL, Yang CH, Litman T, Bates SE, and Schneider E (2000) The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane. Biochem Biophys Res Commun 271:42-46.
-
(2000)
Biochem Biophys Res Commun
, vol.271
, pp. 42-46
-
-
Rocchi, E.1
Khodjakov, A.2
Volk, E.L.3
Yang, C.H.4
Litman, T.5
Bates, S.E.6
Schneider, E.7
-
28
-
-
0033984873
-
Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver
-
Stieger B, Fattinger K, Madon J, Kullak-Ublick GA, and Meier PJ (2000) Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver. Gastroenterology 118:422-430.
-
(2000)
Gastroenterology
, vol.118
, pp. 422-430
-
-
Stieger, B.1
Fattinger, K.2
Madon, J.3
Kullak-Ublick, G.A.4
Meier, P.J.5
-
29
-
-
0038676911
-
Side population cells and Bcrp1 expression in lung
-
Summer R, Kotton DN, Sun X, Ma B, Fitzsimmons K, and Fine A (2003) Side population cells and Bcrp1 expression in lung. Am J Physiol 285:L97-L104.
-
(2003)
Am J Physiol
, vol.285
-
-
Summer, R.1
Kotton, D.N.2
Sun, X.3
Ma, B.4
Fitzsimmons, K.5
Fine, A.6
-
30
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M, Suzuki H, Sugimoto Y, and Sugiyama Y (2003) ABCG2 transports sulfated conjugates of steroids and xenobiotics. J Biol Chem 278:22644-22649.
-
(2003)
J Biol Chem
, vol.278
, pp. 22644-22649
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
31
-
-
0030963906
-
The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis
-
Trauner M, Arrese M, Soroka CJ, Ananthanarayanan M, Koeppel TA, Schlosser SF, Suchy FJ, Keppler D, and Boyer JL (1997) The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 113:255-264.
-
(1997)
Gastroenterology
, vol.113
, pp. 255-264
-
-
Trauner, M.1
Arrese, M.2
Soroka, C.J.3
Ananthanarayanan, M.4
Koeppel, T.A.5
Schlosser, S.F.6
Suchy, F.J.7
Keppler, D.8
Boyer, J.L.9
-
32
-
-
0141919551
-
The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
van Herwaarden AE, Jonker JW, Wagenaar E, Brinkhuis RF, Schellens JH, Beijnen JH, and Schinkel AH (2003) The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine. Cancer Res 63:6447-6452.
-
(2003)
Cancer Res
, vol.63
, pp. 6447-6452
-
-
Van Herwaarden, A.E.1
Jonker, J.W.2
Wagenaar, E.3
Brinkhuis, R.F.4
Schellens, J.H.5
Beijnen, J.H.6
Schinkel, A.H.7
-
33
-
-
0035890194
-
Subcellular compartmentalization and trafficking of the insulin-responsive glucose transporter, GLUT4
-
Watson RT and Pessin JE (2001) Subcellular compartmentalization and trafficking of the insulin-responsive glucose transporter, GLUT4. Exp Cell Res 271:75-83.
-
(2001)
Exp Cell Res
, vol.271
, pp. 75-83
-
-
Watson, R.T.1
Pessin, J.E.2
-
34
-
-
0037125973
-
Bcrp1 gene expression is required for normal numbers of side population stem cells in mice and confers relative protection to mitoxantrone in hematopoietic cells in vivo
-
Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, and Sorrentino BP (2002) Bcrp1 gene expression is required for normal numbers of side population stem cells in mice and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci USA 99:12339-12344.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12339-12344
-
-
Zhou, S.1
Morris, J.J.2
Barnes, Y.3
Lan, L.4
Schuetz, J.D.5
Sorrentino, B.P.6
-
35
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou S, Schuetz JD, Bunting KD, Colapietro AM, Sampath J, Morris JJ, Lagutina I, Grosveld GC, Osawa M, Nakauchi H, et al. (2001) The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat Med 7:1028-1034.
-
(2001)
Nat Med
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.C.8
Osawa, M.9
Nakauchi, H.10
|