Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

Nature

Volumn 425, Issue 6960, 2003, Pages 846-851

  Berman, David M ^a,b   Karhadkar, Sunil S ^a   Maitra, Anirban ^a   De Oca, Rocio Montes ^a   Gerstenblith, Meg R ^a   Briggs, Kimberly ^b   Parker, Antony R ^a   Shimada, Yutaka ^c   Eshleman, James R ^a   Watkins, D Neil ^b   Beachy, Philip A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; GROWTH KINETICS; MUSCLE; MUTAGENESIS; SKIN; TUMORS;

FAMILIAL CONDITIONS; LIGAND EXPRESSION;

GENETIC ENGINEERING;

LIGAND; NEUTRALIZING ANTIBODY; SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ARTICLE; BASAL CELL NEVUS SYNDROME; CELL STIMULATION; DIGESTIVE SYSTEM TUMOR; EPITHELIUM CELL; GENE MUTATION; HEDGEHOG; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TARGET CELL; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; CELL DIVISION; CELL LINE, TUMOR; DIGESTIVE SYSTEM; GASTROINTESTINAL NEOPLASMS; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEDGEHOG PROTEINS; HUMANS; LIGANDS; MEMBRANE PROTEINS; MICE; MICE, NUDE; MUTATION; NEOPLASM TRANSPLANTATION; RECEPTORS, CELL SURFACE; RNA, MESSENGER; RNA, NEOPLASM; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSPLANTATION, HETEROLOGOUS; VERATRUM ALKALOIDS;

ANIMALIA; ERINACEIDAE;

EID: 0242268525     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01972     Document Type: Article

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