메뉴 건너뛰기




Volumn 121, Issue 5, 2003, Pages 1088-1094

Inhibition of the Epidermal Growth Factor Receptor Suppresses Telomerase Activity in HSC-1 Human Cutaneous Squamous Cell Carcinoma Cells

Author keywords

Akt; ERK; Human telomerase catalytic subunit (hTERT); Src

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE; MYC PROTEIN; PROTEIN KINASE B; PROTEIN MAD1; PROTEIN TYROSINE KINASE; TELOMERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 2; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 0242490106     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12529.x     Document Type: Article
Times cited : (44)

References (36)
  • 1
    • 0036645153 scopus 로고    scopus 로고
    • Cytokines modulate telomerase activity in a human multiple myeloma cell line
    • Akiyama M, Hideshima T, Hayashi T, et al: Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res 62:3876-3882, 2002
    • (2002) Cancer Res , vol.62 , pp. 3876-3882
    • Akiyama, M.1    Hideshima, T.2    Hayashi, T.3
  • 3
    • 0036060531 scopus 로고    scopus 로고
    • Retinoic acid inhibits telomerase activity and downregulates expression but does not affect splicing of hTERT: Correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis/multidrug-resistance model
    • Ding Z, Green AG, Yang X, Chernenko G, Tang S-C, Pater A: Retinoic acid inhibits telomerase activity and downregulates expression but does not affect splicing of hTERT: Correlation with cell growth rate inhibition in an in vitro cervical carcinogenesis/multidrug-resistance model. Exp Cell Res 272:185-191, 2002
    • (2002) Exp Cell Res , vol.272 , pp. 185-191
    • Ding, Z.1    Green, A.G.2    Yang, X.3    Chernenko, G.4    Tang, S.-C.5    Pater, A.6
  • 6
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TNF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival
    • Grandis JR, Melhem MF, Gooding WE, et al: Levels of TNF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 90:824-832, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 824-832
    • Grandis, J.R.1    Melhem, M.F.2    Gooding, W.E.3
  • 7
    • 0343673898 scopus 로고    scopus 로고
    • Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1
    • Günes Ç, Lichtsteiner S, Vasserot AP, Englert C: Expression of the hTERT gene is regulated at the level of transcriptional initiation and repressed by Mad1. Cancer Res 60:2116-2121, 2000
    • (2000) Cancer Res , vol.60 , pp. 2116-2121
    • Günes, Ç.1    Lichtsteiner, S.2    Vasserot, A.P.3    Englert, C.4
  • 8
    • 0033925683 scopus 로고    scopus 로고
    • Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity
    • Harada K, Kurisu K, Sadatomo T, Tahara H, Tahara E, Ide T, Tahara E: Growth inhibition of human glioma cells by transfection-induced p21 and its effects on telomerase activity. J Neurooncol 47:39-46, 2000
    • (2000) J Neurooncol , vol.47 , pp. 39-46
    • Harada, K.1    Kurisu, K.2    Sadatomo, T.3    Tahara, H.4    Tahara, E.5    Ide, T.6    Tahara, E.7
  • 9
    • 0029901910 scopus 로고    scopus 로고
    • Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived keratinocytes
    • Harle-Bachor C, Boukamp P: Telomerase activity in the regenerative basal layer of the epidermis in human skin and in immortal and carcinoma-derived keratinocytes. Proc Natl Acad Sci USA 93:6476-6481, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6476-6481
    • Harle-Bachor, C.1    Boukamp, P.2
  • 10
    • 0034543089 scopus 로고    scopus 로고
    • Regulation of keratinocyte function by growth factors
    • Hashimoto K: Regulation of keratinocyte function by growth factors. J Dermatol Sci 24:S46-S50, 2000
    • (2000) J Dermatol Sci , vol.24
    • Hashimoto, K.1
  • 11
    • 0032528051 scopus 로고    scopus 로고
    • Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter
    • He Y, Zeng Q, Drenning SD, Melhem MF, Tweardy DJ, Huang L, Gradis JR: Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst 90:1080-1087, 1998
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1080-1087
    • He, Y.1    Zeng, Q.2    Drenning, S.D.3    Melhem, M.F.4    Tweardy, D.J.5    Huang, L.6    Gradis, J.R.7
  • 12
    • 0035409904 scopus 로고    scopus 로고
    • IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer
    • Herbst RS, Kim ES, Harari PM: IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer. Expert Opin Biol Ther 1:719-732, 2001
    • (2001) Expert Opin Biol Ther , vol.1 , pp. 719-732
    • Herbst, R.S.1    Kim, E.S.2    Harari, P.M.3
  • 13
    • 0029973653 scopus 로고    scopus 로고
    • Regulation of telomerase activity in immortal cell lines
    • Holt SE, Wright WE, Shay JW: Regulation of telomerase activity in immortal cell lines. Mol Cell Biol 16:2932-2939, 1996
    • (1996) Mol Cell Biol , vol.16 , pp. 2932-2939
    • Holt, S.E.1    Wright, W.E.2    Shay, J.W.3
  • 14
    • 0033558281 scopus 로고    scopus 로고
    • Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene
    • Horikawa I, Cable PL, Afshari C, Barrett JC: Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res 59:826-830, 1999
    • (1999) Cancer Res , vol.59 , pp. 826-830
    • Horikawa, I.1    Cable, P.L.2    Afshari, C.3    Barrett, J.C.4
  • 17
    • 0033532056 scopus 로고    scopus 로고
    • Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit
    • Kang SS, Kwon T, Kwon DY, Do SI: Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit. J Biol Chem 274:13085-13090, 1999
    • (1999) J Biol Chem , vol.274 , pp. 13085-13090
    • Kang, S.S.1    Kwon, T.2    Kwon, D.Y.3    Do, S.I.4
  • 19
    • 0019490616 scopus 로고
    • Establishment of a cell line of human skin squamous cell carcinoma in vivo
    • Kondo S, Aso K: Establishment of a cell line of human skin squamous cell carcinoma in vivo. Br J Dermatol 105:125-132, 1981
    • (1981) Br J Dermatol , vol.105 , pp. 125-132
    • Kondo, S.1    Aso, K.2
  • 20
    • 0037148327 scopus 로고    scopus 로고
    • Complex regulatory mechanisms of telomerase activity in normal and cancer cell: How can we apply them for cancer therapy?
    • Kyo S, Inoue M: Complex regulatory mechanisms of telomerase activity in normal and cancer cell: How can we apply them for cancer therapy? Oncogene 21: 688-697, 2002
    • (2002) Oncogene , vol.21 , pp. 688-697
    • Kyo, S.1    Inoue, M.2
  • 21
    • 0033406452 scopus 로고    scopus 로고
    • Estrogen activates telomerase
    • Kyo S, Takakura M, Kanaya T, et al: Estrogen activates telomerase. Cancer Res 59: 5917-5921, 1999
    • (1999) Cancer Res , vol.59 , pp. 5917-5921
    • Kyo, S.1    Takakura, M.2    Kanaya, T.3
  • 22
    • 0034142386 scopus 로고    scopus 로고
    • Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT)
    • Kyo S, Takakura M, Taira T, et al: Sp1 cooperates with c-Myc to activate transcription of the human telomerase reverse transcriptase gene (hTERT). Nucl Acids Res 28:669-677, 2000
    • (2000) Nucl Acids Res , vol.28 , pp. 669-677
    • Kyo, S.1    Takakura, M.2    Taira, T.3
  • 23
    • 0035809086 scopus 로고    scopus 로고
    • Activation of extracellular-regulated kinases by normal and mutant EGF receptors
    • Lorimer IAJ, Lavictoire SJ: Activation of extracellular-regulated kinases by normal and mutant EGF receptors. Biochim Biophys Acta 1538:1-9, 2001
    • (2001) Biochim Biophys Acta , vol.1538 , pp. 1-9
    • Lorimer, I.A.J.1    Lavictoire, S.J.2
  • 24
    • 18444377359 scopus 로고    scopus 로고
    • Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway
    • Maida Y, Kyo S, Kanaya T, et al: Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway. Oncogene 21:4701-4709, 2002
    • (2002) Oncogene , vol.21 , pp. 4701-4709
    • Maida, Y.1    Kyo, S.2    Kanaya, T.3
  • 25
    • 0034624675 scopus 로고    scopus 로고
    • Identification of Mad as a repressor of the human telomerase (hTERT) gene
    • Oh S, Song Y-H, Yim J, Kim TK: Identification of Mad as a repressor of the human telomerase (hTERT) gene. Oncogene 19:1485-1490, 2000
    • (2000) Oncogene , vol.19 , pp. 1485-1490
    • Oh, S.1    Song, Y.-H.2    Yim, J.3    Kim, T.K.4
  • 26
    • 0028171075 scopus 로고
    • Epidermal-growth-factor-dependent activation of the Src-family kinases
    • Osherov N, Levitzki A: Epidermal-growth-factor-dependent activation of the Src-family kinases. Eur J Biochem 225:1047-1053, 1994
    • (1994) Eur J Biochem , vol.225 , pp. 1047-1053
    • Osherov, N.1    Levitzki, A.2
  • 27
    • 0035545835 scopus 로고    scopus 로고
    • Telomerase deregulation in immortalized human epidermal cells: Modulation by cellular microenvironment
    • Rea MA, Rice RH: Telomerase deregulation in immortalized human epidermal cells: Modulation by cellular microenvironment. Int J Cancer 94:669-673, 2001
    • (2001) Int J Cancer , vol.94 , pp. 669-673
    • Rea, M.A.1    Rice, R.H.2
  • 28
    • 0033526838 scopus 로고    scopus 로고
    • Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells
    • Seimiya H, Tanji M, Oh-hara T, Tomida A, Naasani I, Tsuruo T: Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells. Biochem Biophys Res Commun 260:365-370, 1999
    • (1999) Biochem Biophys Res Commun , vol.260 , pp. 365-370
    • Seimiya, H.1    Tanji, M.2    Oh-hara, T.3    Tomida, A.4    Naasani, I.5    Tsuruo, T.6
  • 29
    • 0034697962 scopus 로고    scopus 로고
    • The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development
    • Sibilia M, Fleichmann A, Behrens A, et al: The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development. Cell 102:211-220, 2000
    • (2000) Cell , vol.102 , pp. 211-220
    • Sibilia, M.1    Fleichmann, A.2    Behrens, A.3
  • 30
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura M, Kyo S, Kanaya T, Hirano H, Takeda J, Yutsudo M, Inoue M: Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res 59:551-557, 1999
    • (1999) Cancer Res , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7
  • 31
    • 0031042892 scopus 로고    scopus 로고
    • Evidence for UV-associated activation of telomerase in human skin
    • Ueda M, Ouhtit A, Bito T, et al: Evidence for UV-associated activation of telomerase in human skin. Cancer Res 57:370-374, 1997
    • (1997) Cancer Res , vol.57 , pp. 370-374
    • Ueda, M.1    Ouhtit, A.2    Bito, T.3
  • 32
    • 0034307337 scopus 로고    scopus 로고
    • Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen-activated protein kinase signaling pathway
    • Wang Z, Kyo S, Takakura M, et al: Progesterone regulates human telomerase reverse transcriptase gene expression via activation of mitogen-activated protein kinase signaling pathway. Cancer Res 60:5376-5381, 2000
    • (2000) Cancer Res , vol.60 , pp. 5376-5381
    • Wang, Z.1    Kyo, S.2    Takakura, M.3
  • 33
    • 0033571329 scopus 로고    scopus 로고
    • Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors
    • Wu A, Ichihashi M, Ueda M: Correlation of the expression of human telomerase subunits with telomerase activity in normal skin and skin tumors. Cancer 86:2038-2044, 1999
    • (1999) Cancer , vol.86 , pp. 2038-2044
    • Wu, A.1    Ichihashi, M.2    Ueda, M.3
  • 35
    • 0030891767 scopus 로고    scopus 로고
    • Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: Possible role in mouse skin tumor promotion
    • Xian W, Rosenberg MP, DiGiovanni J: Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: Possible role in mouse skin tumor promotion. Oncogene 14:1435-1444, 1997
    • (1997) Oncogene , vol.14 , pp. 1435-1444
    • Xian, W.1    Rosenberg, M.P.2    DiGiovanni, J.3
  • 36
    • 0029941308 scopus 로고    scopus 로고
    • Cell cycle-dependent modulation of telomerase activity in tumor cells
    • Zhu X, Kumar R, Mandal M, et al: Cell cycle-dependent modulation of telomerase activity in tumor cells. Proc Natl Acad Sci USA 93:6091-6095, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6091-6095
    • Zhu, X.1    Kumar, R.2    Mandal, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.