Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system

Neuron

Volumn 25, Issue 2, 2000, Pages 317-329

  Lu, Q Richard ^a   Yuk, Dong In ^a   Alberta, John A ^a   Zhu, Zhimin ^a   Pawlitzky, Inka ^a   Chan, Joanne ^a   McMahon, Andrew P ^b   Stiles, Charles D ^a   Rowitch, David H ^c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD UNIVERSITY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ADOLESCENT; ANIMAL CELL; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; GENE STRUCTURE; MAMMAL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; SEQUENCE HOMOLOGY; STEM CELL; TRANSGENIC MOUSE;

EID: 0033767315     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80897-1     Document Type: Article

References (66)

1. A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development
2. Cillary neurotrophic factor enhances the rate of oligodendrocyte generation
3. Expression of the APC tumor suppressor protein in oligodendroglia
4. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
5. Is PDGF really important? Testing the hypothesis
6. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signaling
7. Oligodendrocyte population dynamics and the role of PDGF in vivo
8. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
9. Expression of a single transfected cDNA converts fibroblasts to myoblasts
10. Sonic hedgehog promotes neuronal differentiation of murine spinal cord precursors and collaborates with neurotrophin 3 to induce Islet-1
11. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
12. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS
13. Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
14. Graded sonic hedgehog signaling and the specification of cell fate in the ventral neural tube
15. Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice
16. Bone morphogenic proteins promote astroglial lineage commitment by mammalian subventricular zone progenitor cells
17. Differential regulation of transription factor gene expression and phenotypic markers in developing sympathetic neruons
18. Spinal cord oligodendrocytes develop from ventrally derived progenitor cells that express PDGF alpha-receptors
19. Dorsoventral patterning and oligodendroglial specification in the developing central nervous system
20. A simplified system for generating recombinant adenoviruses
21. Structure of platelet-derived growth factor: Implications for functional properties
22. Glia cells missing: A binary switch between neuronal and glial determination in Drosophila
23. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system
24. Glial cells missing: A genetic switch that controls glial versus neuronal fate
25. Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing
26. The Ets transcription factors encoded by the Drosophila gene pointed direct glial cell differentiation in the embryonic CNS
27. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
28. Neuronal influences on glial progenitor cell development
29. The NG2 chondroitin sulfate proteoglycan: A multifunctional proteoglycan associated with immature cells
30. Specification of neurotransmitter identity by Phox2 proteins in neural crest stem cells
31. Identification of neurogenin, a vertebrate neuronal determination gene
32. Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands
33. Distribution of Sonic hedgehog peptides in the developing chick and mouse embryo
34. Selective expression of PDGF A and its receptor during early mouse embryogenesis
35. Regulatory mechanisms in stem cell biology
36. Oligodendrocyte precursors originate at the ventral ventricular zone dorsal to the ventral midline region in the embryonic rat spinal cord
37. Early development and dispersal of oligodendrocyte precursors in the embryonic chick spinal cord
38. Sonic hedgehog signaling is required during the appearance of spinal cord oligodendrocyte precursors
39. Binary system for regulating transgene expression in mice: Targeting int-2 expression with yeast GAL4/UAS elements
40. Requirement for LIM homeobox gene lsl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation
41. Induction of oligodendrocyte progenitors in the trunk neural tube by ventralizing signals: Effects of notochord and floor plate grafts, and of sonic hedgehog
42. Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain
43. A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage
44. Determination of neuroepithelial cell fate: Induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog
45. Dorsal spinal cord neuroepithelium generates astrocytes but not oligodendrocytes
46. FGF2 concentration regulates the generation of neurons and gila from multipotent cortical stem cells
47. Expression of platelet-derived growth factor (PDGF) and PDGF receptor genes in the developing rat brain
48. Oligodendroglial progenitors labeled with the O4 antibody persist in the adult rat cerebral cortex in vivo
49. Oligodendrocyte lineage and the motor neuron connection
50. Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
51. Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
52. Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells
53. Identification by differential RT-PCR of a novel paired homeodomain protein specifically expressed in sensory neurons and a subset of their CNS targets
54. Neural stem cells are blasting off
55. Sonic hedgehog signaling is essential for hair development
56. Roles of Paz-genes in developing and adult brain as suggested by expression patterns
57. Pax6 influences the time and site of origin of glial precursors in the ventral neural tube
58. Diversity and pattern in the developing spinal cord
59. Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation
60. Specification of motor neuron identity by the MNR2 homeodomain protein
61. Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression
62. The myoD gene family: Nodal point during specification of the muscle cell lineage
63. Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts
64. Evidence for multiple precursor cell types in the embryonic rat cerebral cortex
65. A PDG F-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells
66. Embryonic expression of myelin genes: Evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neurol tube