메뉴 건너뛰기




Volumn 10, Issue 2, 2010, Pages 137-151

Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies

Author keywords

Combination cancer therapy; Epithelial cancers; Pancreatic cancer stem progenitor cells; Prostate cancer stem progenitor cells; Targeted therapy; Treatment resistance

Indexed keywords

ABC TRANSPORTER; ALDEHYDE DEHYDROGENASE; ANTISENSE OLIGODEOXYNUCLEOTIDE; BETA CATENIN; BMI1 PROTEIN; CHEMOKINE RECEPTOR CXCR4; CYCLIN DEPENDENT KINASE INHIBITOR 2A; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERLOTINIB; GEFITINIB; GLYCOPROTEIN P; GROWTH FACTOR; HERMES ANTIGEN; HYALURONIC ACID; INTERLEUKIN 6; MONOCLONAL ANTIBODY; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN P53; RETINOBLASTOMA PROTEIN; SONIC HEDGEHOG PROTEIN; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1; TELOMERASE REVERSE TRANSCRIPTASE; TEMOZOLOMIDE; TRASTUZUMAB; UNINDEXED DRUG; WNT PROTEIN;

EID: 77950793274     PISSN: 18715206     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152010790909353     Document Type: Review
Times cited : (12)

References (241)
  • 1
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in selfrenewal capacity
    • Hope, K.J.; Jin, L.; Dick, J.E. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in selfrenewal capacity. Nat. Immunol., 2004, 5(7), 738-743.
    • (2004) Nat. Immunol. , vol.5 , Issue.7 , pp. 738-743
    • Hope, K.J.1    Jin, L.2    Dick, J.E.3
  • 12
    • 34548455927 scopus 로고    scopus 로고
    • Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer
    • Hermann, P.C.; Huber, S.L.; Herrler, T.; Aicher, A.; Ellwart, J.W.; Guba, M.; Bruns, C.J.; Heeschen, C. Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell. Stem Cell, 2007, 1(3), 313-323.
    • (2007) Cell. Stem Cell , vol.1 , Issue.3 , pp. 313-323
    • Hermann, P.C.1    Huber, S.L.2    Herrler, T.3    Aicher, A.4    Ellwart, J.W.5    Guba, M.6    Bruns, C.J.7    Heeschen, C.8
  • 17
    • 35648999534 scopus 로고    scopus 로고
    • Recent advances on cancer stem/progenitor cell research: Therapeutic implications for overcoming resistance to the most aggressive cancers
    • Mimeault, M.; Hauke, R.; Mehta, P.P.; Batra, S.K. Recent advances on cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers. J. Mol. Cell. Med., 2007, 11(5), 981-1011.
    • (2007) J. Mol. Cell. Med. , vol.11 , Issue.5 , pp. 981-1011
    • Mimeault, M.1    Hauke, R.2    Mehta, P.P.3    Batra, S.K.4
  • 20
    • 65349130616 scopus 로고    scopus 로고
    • Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines
    • Huang, D.; Gao, Q.; Guo, L.; Zhang, C.; Wei, J.; Li, H.; Jing, W.J.; Han, X.; Shi, Y.; Shih, H.L. Isolation and identification of cancer stem-like cells in esophageal carcinoma cell lines. Stem Cells Dev., 2009, 18(3), 465-473.
    • (2009) Stem Cells Dev. , vol.18 , Issue.3 , pp. 465-473
    • Huang, D.1    Gao, Q.2    Guo, L.3    Zhang, C.4    Wei, J.5    Li, H.6    Jing, W.J.7    Han, X.8    Shi, Y.9    Shih, H.L.10
  • 21
    • 56449117381 scopus 로고    scopus 로고
    • Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro
    • Huang, Q.; Zhang, Q.B.; Dong, J.; Wu, Y.Y.; Shen, Y.T.; Zhao, Y.D.; Zhu, Y.D.; Diao, Y.; Wang, A.D.; Lan, Q. Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro. BMC Cancer, 2008, 8, 304.
    • (2008) BMC Cancer , vol.8 , pp. 304
    • Huang, Q.1    Zhang, Q.B.2    Dong, J.3    Wu, Y.Y.4    Shen, Y.T.5    Zhao, Y.D.6    Zhu, Y.D.7    Diao, Y.8    Wang, A.D.9    Lan, Q.10
  • 25
    • 33744985294 scopus 로고    scopus 로고
    • Characterization of a side population of cancer cells from human gastrointestinal system
    • Haraguchi, N.; Utsunomiya, T.; Inoue, H.; Tanaka, F.; Mimori, K.; Barnard, G.F.; Mori, M. Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells, 2006, 24(3), 506-513.
    • (2006) Stem Cells , vol.24 , Issue.3 , pp. 506-513
    • Haraguchi, N.1    Utsunomiya, T.2    Inoue, H.3    Tanaka, F.4    Mimori, K.5    Barnard, G.F.6    Mori, M.7
  • 27
    • 34248529666 scopus 로고    scopus 로고
    • Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line
    • Wang, J.; Guo, L.P.; Chen, L.Z.; Zeng, Y.X.; Lu, S.H. Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line. Cancer Res., 2007, 67(8), 3716-3724.
    • (2007) Cancer Res. , vol.67 , Issue.8 , pp. 3716-3724
    • Wang, J.1    Guo, L.P.2    Chen, L.Z.3    Zeng, Y.X.4    Lu, S.H.5
  • 28
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat, S.A.; Mali, A.M.; Koppikar, C.B.; Kurrey, N.K. Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res., 2005, 65(8), 3025-3029.
    • (2005) Cancer Res. , vol.65 , Issue.8 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 29
    • 54249132606 scopus 로고    scopus 로고
    • The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma
    • Chiba, T.; Miyagi, S.; Saraya, A.; Aoki, R.; Seki, A.; Morita, Y.; Yonemitsu, Y.; Yokosuka, O.; Taniguchi, H.; Nakauchi, H.; Iwama, A. The polycomb gene product BMI1 contributes to the maintenance of tumor-initiating side population cells in hepatocellular carcinoma. Cancer Res., 2008, 68(19), 7742-7749.
    • (2008) Cancer Res. , vol.68 , Issue.19 , pp. 7742-7749
    • Chiba, T.1    Miyagi, S.2    Saraya, A.3    Aoki, R.4    Seki, A.5    Morita, Y.6    Yonemitsu, Y.7    Yokosuka, O.8    Taniguchi, H.9    Nakauchi, H.10    Iwama, A.11
  • 30
    • 33846330973 scopus 로고    scopus 로고
    • Cancer stem cells and "stemness" genes in neurooncology
    • Nicolis, S.K. Cancer stem cells and "stemness" genes in neurooncology. Neurobiol. Dis., 2007, 25(2), 217-229.
    • (2007) Neurobiol. Dis. , vol.25 , Issue.2 , pp. 217-229
    • Nicolis, S.K.1
  • 31
    • 34247891719 scopus 로고    scopus 로고
    • A translational view of the molecular pathogenesis of lung cancer
    • Sato, M.; Shames, D.S.; Gazdar, A.F.; Minna, J.D. A translational view of the molecular pathogenesis of lung cancer. J. Thorac. Oncol., 2007, 2(4), 327-343.
    • (2007) J. Thorac. Oncol. , vol.2 , Issue.4 , pp. 327-343
    • Sato, M.1    Shames, D.S.2    Gazdar, A.F.3    Minna, J.D.4
  • 32
    • 33847220364 scopus 로고    scopus 로고
    • Melanoma biology and new targeted therapy
    • Gray-Schopfer, V.; Wellbrock, C.; Marais, R. Melanoma biology and new targeted therapy. Nature, 2007, 445(7130), 851-857.
    • (2007) Nature , vol.445 , Issue.7130 , pp. 851-857
    • Gray-Schopfer, V.1    Wellbrock, C.2    Marais, R.3
  • 33
    • 40749150740 scopus 로고    scopus 로고
    • CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • Ma, S.; Lee, T.K.; Zheng, B.J.; Chan, K.W.; Guan, X.Y. CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene, 2008, 27(12), 1749-1758.
    • (2008) Oncogene , vol.27 , Issue.12 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 34
    • 35148888629 scopus 로고    scopus 로고
    • Cancer stem cells in radiation resistance
    • Rich, J.N. Cancer stem cells in radiation resistance. Cancer Res., 2007, 67(19), 8980-8984.
    • (2007) Cancer Res. , vol.67 , Issue.19 , pp. 8980-8984
    • Rich, J.N.1
  • 35
    • 25444495269 scopus 로고    scopus 로고
    • Opinion: Migrating cancer stem cells - An integrated concept of malignant tumour progression
    • Brabletz, T.; Jung, A.; Spaderna, S.; Hlubek, F.; Kirchner, T. Opinion: migrating cancer stem cells - an integrated concept of malignant tumour progression. Nat. Rev. Cancer, 2005, 5(9), 744-749.
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.9 , pp. 744-749
    • Brabletz, T.1    Jung, A.2    Spaderna, S.3    Hlubek, F.4    Kirchner, T.5
  • 37
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao, S.; Wu, Q., McLendon, R.E.; Hao, Y.; Shi, Q.; Hjelmeland, A.B.; Dewhirst, M.W.; Bigner, D.D.; Rich, J.N. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature, 2006, 444(7120), 756-760.
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6    Dewhirst, M.W.7    Bigner, D.D.8    Rich, J.N.9
  • 38
    • 34247635666 scopus 로고    scopus 로고
    • Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression
    • Sengupta, A.; Banerjee, D.; Chandra, S.; Banerji, S.K.; Ghosh, R.; Roy, R.; Banerjee, S. Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression. Leukemia, 2007, 21, 949-955.
    • (2007) Leukemia , vol.21 , pp. 949-955
    • Sengupta, A.1    Banerjee, D.2    Chandra, S.3    Banerji, S.K.4    Ghosh, R.5    Roy, R.6    Banerjee, S.7
  • 39
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu, S.; Dontu, G.; Mantle, I.D.; Patel, S.; Ahn, N.S.; Jackson, K.W.; Suri, P.; Wicha, M.S. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res., 2006, 66(12), 6063-6071.
    • (2006) Cancer Res. , vol.66 , Issue.12 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 40
    • 33646428091 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: The niche matters
    • Li, L.; Neaves, W.B. Normal stem cells and cancer stem cells: the niche matters. Cancer Res., 2006, 66(9), 4553-4557.
    • (2006) Cancer Res. , vol.66 , Issue.9 , pp. 4553-4557
    • Li, L.1    Neaves, W.B.2
  • 41
    • 34748837360 scopus 로고    scopus 로고
    • Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis
    • Katoh, M. Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev., 2007, 3(1), 30-38.
    • (2007) Stem Cell Rev. , vol.3 , Issue.1 , pp. 30-38
    • Katoh, M.1
  • 42
    • 60949100188 scopus 로고    scopus 로고
    • Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications
    • Mimeault, M.; Batra, S.K. Recent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications. Ageing Res. Rev., 2009, 8(2), 94-112.
    • (2009) Ageing Res. Rev. , vol.8 , Issue.2 , pp. 94-112
    • Mimeault, M.1    Batra, S.K.2
  • 43
    • 34347330516 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells
    • Onoue, T.; Uchida, D.; Begum, N.M.; Tomizuka, Y.; Yoshida, H.; Sato, M. Epithelial-mesenchymal transition induced by the stromal cell-derived factor-1/CXCR4 system in oral squamous cell carcinoma cells. Int. J. Oncol., 2006, 29(5), 1133-1138.
    • (2006) Int. J. Oncol. , vol.29 , Issue.5 , pp. 1133-1138
    • Onoue, T.1    Uchida, D.2    Begum, N.M.3    Tomizuka, Y.4    Yoshida, H.5    Sato, M.6
  • 44
    • 45549098737 scopus 로고    scopus 로고
    • "Stemness" genomics law governs clinical behavior of human cancer: Implications for decision making in disease management
    • Glinsky, G.V. "Stemness" genomics law governs clinical behavior of human cancer: implications for decision making in disease management. J. Clin. Oncol., 2008, 26(17), 2846-2853.
    • (2008) J. Clin. Oncol. , vol.26 , Issue.17 , pp. 2846-2853
    • Glinsky, G.V.1
  • 45
    • 34848851037 scopus 로고    scopus 로고
    • Interplay of distinct growth factors during epithelial-mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies
    • Mimeault, M.; Batra, S.K. Interplay of distinct growth factors during epithelial-mesenchymal transition of cancer progenitor cells and molecular targeting as novel cancer therapies. Ann. Oncol., 2007, 18(10), 1605-1619.
    • (2007) Ann. Oncol. , vol.18 , Issue.10 , pp. 1605-1619
    • Mimeault, M.1    Batra, S.K.2
  • 46
    • 33947374762 scopus 로고    scopus 로고
    • Functions of tumorigenic and migrating cancer progenitor cells in cancer progression and metastasis and their therapeutic implications
    • Mimeault, M.; Batra, S.K. Functions of tumorigenic and migrating cancer progenitor cells in cancer progression and metastasis and their therapeutic implications. Cancer Metastasis Rev., 2007, 26(1), 203-214.
    • (2007) Cancer Metastasis Rev. , vol.26 , Issue.1 , pp. 203-214
    • Mimeault, M.1    Batra, S.K.2
  • 47
    • 44949115149 scopus 로고    scopus 로고
    • Targeting of cancer stem/progenitor cells plus stem cell-based therapies: The ultimate hope for treating and curing aggressive and recurrent cancers
    • Mimeault, M.; Batra, S.K. Targeting of cancer stem/progenitor cells plus stem cell-based therapies: the ultimate hope for treating and curing aggressive and recurrent cancers. Panminerva Med., 2008, 50(1), 3-18.
    • (2008) Panminerva Med. , vol.50 , Issue.1 , pp. 3-18
    • Mimeault, M.1    Batra, S.K.2
  • 48
    • 42049121143 scopus 로고    scopus 로고
    • Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies
    • Mimeault, M.; Mehta, P.P.; Hauke, R.; Batra, S.K. Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies. Endocr. Rev., 2008, 29(2), 234-252.
    • (2008) Endocr. Rev. , vol.29 , Issue.2 , pp. 234-252
    • Mimeault, M.1    Mehta, P.P.2    Hauke, R.3    Batra, S.K.4
  • 49
    • 52649091291 scopus 로고    scopus 로고
    • Recent progress on normal and malignant pancreatic stem/progenitor cell research: Therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer
    • Mimeault, M.; Batra, S.K. Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer. Gut, 2008, 57(10), 1456-1468.
    • (2008) Gut , vol.57 , Issue.10 , pp. 1456-1468
    • Mimeault, M.1    Batra, S.K.2
  • 50
    • 44449149171 scopus 로고    scopus 로고
    • Dynamic control of TGF-beta signaling and its links to the cytoskeleton
    • Moustakas, A.; Heldin, C.H. Dynamic control of TGF-beta signaling and its links to the cytoskeleton. FEBS Lett., 2008, 582(14), 2051-2065.
    • (2008) FEBS Lett. , vol.582 , Issue.14 , pp. 2051-2065
    • Moustakas, A.1    Heldin, C.H.2
  • 51
    • 75449087368 scopus 로고    scopus 로고
    • Integrative genomic analyses of CXCR4: Transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors
    • Katoh, M.; Katoh, M. Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. Int. J. Oncol., 2010, 36(2), 415-420.
    • (2010) Int. J. Oncol. , vol.36 , Issue.2 , pp. 415-420
    • Katoh, M.1    Katoh, M.2
  • 52
    • 54249151684 scopus 로고    scopus 로고
    • Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
    • Das, B.; Tsuchida, R.; Malkin, D.; Koren, G.; Baruchel, S.; Yeger, H. Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction. Stem Cells, 2008, 26(7), 1818-1830.
    • (2008) Stem Cells , vol.26 , Issue.7 , pp. 1818-1830
    • Das, B.1    Tsuchida, R.2    Malkin, D.3    Koren, G.4    Baruchel, S.5    Yeger, H.6
  • 53
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery, J.P.; Sleeman, J.P. Complex networks orchestrate epithelial-mesenchymal transitions. Nat. Rev. Mol. Cell Biol., 2006, 7(2), 131-142.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 54
    • 25144488085 scopus 로고    scopus 로고
    • Hedgehog and snail: Sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis
    • Zhou, B.P.; Hung, M.C. Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis. Cell Cycle, 2006, 4(6), 772-776.
    • (2006) Cell Cycle , vol.4 , Issue.6 , pp. 772-776
    • Zhou, B.P.1    Wnt, H.C.M.2
  • 55
    • 42649137241 scopus 로고    scopus 로고
    • Mechanisms of disease: Epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?
    • Turley, E.A.; Veiseh, M.; Radisky, D.C.; Bissell, M.J. Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression? Nat. Clin. Pract. Oncol., 2008, 5(5), 280-290.
    • (2008) Nat. Clin. Pract. Oncol. , vol.5 , Issue.5 , pp. 280-290
    • Turley, E.A.1    Veiseh, M.2    Radisky, D.C.3    Bissell, M.J.4
  • 60
    • 36349006961 scopus 로고    scopus 로고
    • Development and characterization of gemcitabineresistant pancreatic tumor cells
    • Shah, A.N.; Summy, J.M.; Zhang, J.; Park, S.I.; Parikh, N.U.; Gallick, G.E. Development and characterization of gemcitabineresistant pancreatic tumor cells. Ann. Surg. Oncol., 2007, 14(12), 3629-3637.
    • (2007) Ann. Surg. Oncol. , vol.14 , Issue.12 , pp. 3629-3637
    • Shah, A.N.1    Summy, J.M.2    Zhang, J.3    Park, S.I.4    Parikh, N.U.5    Gallick, G.E.6
  • 61
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression
    • Moustakas, A.; Heldin, C.H. Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression. Cancer Sci., 2007, 98(10), 1512-1520.
    • (2007) Cancer Sci. , vol.98 , Issue.10 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.H.2
  • 62
    • 53949090765 scopus 로고    scopus 로고
    • NF-kappaB signaling pathway and its therapeutic implications in human diseases
    • Sarkar, F.H.; Li, Y.; Wang, Z.; Kong, D. NF-kappaB signaling pathway and its therapeutic implications in human diseases. Int. Rev. Immunol., 2008, 27(5), 293-319.
    • (2008) Int. Rev. Immunol. , vol.27 , Issue.5 , pp. 293-319
    • Sarkar, F.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 65
    • 34547128128 scopus 로고    scopus 로고
    • Hierarchical organization of prostate cancer cells in xenograft tumors: The CD44+{alpha}2{beta}1+ cell population is enriched in tumor-initiating cells
    • Patrawala, L.; Calhoun-Davis, T.; Schneider-Broussard, R.; Tang, D.G. Hierarchical organization of prostate cancer cells in xenograft tumors: The CD44+{alpha}2{beta}1+ cell population is enriched in tumor-initiating cells. Cancer Res., 2007, 67(14), 6796-6805.
    • (2007) Cancer Res. , vol.67 , Issue.14 , pp. 6796-6805
    • Patrawala, L.1    Calhoun-Davis, T.2    Schneider-Broussard, R.3    Tang, D.G.4
  • 66
    • 34548218695 scopus 로고    scopus 로고
    • Cancer stem-like cells in human prostate carcinoma cells DU145: The seeds of the cell line?
    • Wei, C.; Guomin, W.; Yujun, L.; Ruizhe, Q. Cancer stem-like cells in human prostate carcinoma cells DU145: The seeds of the cell line? Cancer Biol. Ther., 2007, 6(5), 763-768.
    • (2007) Cancer Biol. Ther. , vol.6 , Issue.5 , pp. 763-768
    • Wei, C.1    Guomin, W.2    Yujun, L.3    Ruizhe, Q.4
  • 68
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore, C.M.; Kuperwasser, C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res., 2008, 10(2), R25.
    • (2008) Breast Cancer Res. , vol.10 , Issue.2
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 71
    • 75449106680 scopus 로고    scopus 로고
    • Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
    • Aktas, B.; Tewes, M.; Fehm, T.; Hauch, S.; Kimmig, R.; Kasimir-Bauer, S. Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients. Breast Cancer Res., 2009, 11(4), R46.
    • (2009) Breast Cancer Res. , vol.11 , Issue.4
    • Aktas, B.1    Tewes, M.2    Fehm, T.3    Hauch, S.4    Kimmig, R.5    Kasimir-Bauer, S.6
  • 72
    • 33750306612 scopus 로고    scopus 로고
    • Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype
    • Balic, M.; Lin, H.; Young, L.; Hawes, D.; Giuliano, A.; McNamara, G.; Datar, R.H.; Cote, R.J. Most early disseminated cancer cells detected in bone marrow of breast cancer patients have a putative breast cancer stem cell phenotype. Clin. Cancer Res. 2006, 12(19), 5615-5621.
    • (2006) Clin. Cancer Res. , vol.12 , Issue.19 , pp. 5615-5621
    • Balic, M.1    Lin, H.2    Young, L.3    Hawes, D.4    Giuliano, A.5    McNamara, G.6    Datar, R.H.7    Cote, R.J.8
  • 74
    • 52049099166 scopus 로고    scopus 로고
    • Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus
    • Zhang, X.; Komaki, R.; Wang, L.; Fang, B.; Chang, J.Y. Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus. Clin. Cancer Res., 2008, 14(9), 2813-2823.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.9 , pp. 2813-2823
    • Zhang, X.1    Komaki, R.2    Wang, L.3    Fang, B.4    Chang, J.Y.5
  • 78
    • 42449161959 scopus 로고    scopus 로고
    • Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies
    • Mimeault, M.; Hauke, R.; Batra, S.K. Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies. Clin. Pharmacol. Ther., 2008, 83(5), 673-691.
    • (2008) Clin. Pharmacol. Ther. , vol.83 , Issue.5 , pp. 673-691
    • Mimeault, M.1    Hauke, R.2    Batra, S.K.3
  • 79
    • 52449091004 scopus 로고    scopus 로고
    • Drug-selected human lung cancer stem cells: Cytokine network, tumorigenic and metastatic properties
    • Levina, V.; Marrangoni, A.M.; DeMarco, R.; Gorelik, E.; Lokshin, A..E. Drug-selected human lung cancer stem cells: cytokine network, tumorigenic and metastatic properties. PLoS ONE, 2008, 3(8), e3077.
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Levina, V.1    Marrangoni, A.M.2    Demarco, R.3    Gorelik, E.4    Lokshin, A.E.5
  • 80
    • 33845904383 scopus 로고    scopus 로고
    • The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation
    • Phillips, T.M.; McBride, W.H.; Pajonk, F. The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation. J. Natl. Cancer Inst., 2006, 98(24), 1777-1785.
    • (2006) J. Natl. Cancer Inst. , vol.98 , Issue.24 , pp. 1777-1785
    • Phillips, T.M.1    McBride, W.H.2    Pajonk, F.3
  • 81
    • 50849086732 scopus 로고    scopus 로고
    • DNA repair and cancer stem-like cells - Potential partners in glioma drug resistance
    • Johannessen, T.C.; Bjerkvig, R.; Tysnes, B.B. DNA repair and cancer stem-like cells - Potential partners in glioma drug resistance? Cancer Treat. Rev., 2008, 34(6), 558-567.
    • (2008) Cancer Treat. Rev. , vol.34 , Issue.6 , pp. 558-567
    • Johannessen, T.C.1    Bjerkvig, R.2    Tysnes, B.B.3
  • 85
    • 34147208233 scopus 로고    scopus 로고
    • Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications
    • Vaish, M. Mismatch repair deficiencies transforming stem cells into cancer stem cells and therapeutic implications. Mol. Cancer, 2007, 6, 26.
    • (2007) Mol. Cancer , vol.6 , pp. 26
    • Vaish, M.1
  • 86
    • 49849094172 scopus 로고    scopus 로고
    • Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: Implications on lung carcinogenesis
    • Catassi, A.; Servent, D.; Paleari, L.; Cesario, A.; Russo, P. Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: implications on lung carcinogenesis. Mutat. Res., 2008, 659(3), 221-231.
    • (2008) Mutat. Res. , vol.659 , Issue.3 , pp. 221-231
    • Catassi, A.1    Servent, D.2    Paleari, L.3    Cesario, A.4    Russo, P.5
  • 87
    • 34047221962 scopus 로고    scopus 로고
    • Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency
    • Nijhof, J.G.; van Pelt C.; Mulder, A.A., Mitchell, D.L.; Mullenders, L.H.; de Gruijl, F.R. Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency. Carcinogenesis, 2007, 28(4), 792-800.
    • (2007) Carcinogenesis , vol.28 , Issue.4 , pp. 792-800
    • Nijhof, J.G.1    Van Pelt, C.2    Mulder, A.A.3    Mitchell, D.L.4    Mullenders, L.H.5    De Gruijl, F.R.6
  • 88
    • 42149185640 scopus 로고    scopus 로고
    • Telomeres and aging
    • Aubert, G.; Lansdorp, P.M. Telomeres and aging. Physiol. Rev., 2008, 88(2), 557-579.
    • (2008) Physiol. Rev. , vol.88 , Issue.2 , pp. 557-579
    • Aubert, G.1    Lansdorp, P.M.2
  • 89
    • 42349089231 scopus 로고    scopus 로고
    • Neural stem cells, inflammation and NF-kappaB: Basic principle of maintenance and repair or origin of brain tumours?
    • Widera, D.; Kaus, A.; Kaltschmidt, C.; Kaltschmidt, B. Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours? J. Cell. Mol. Med., 2008, 12(2), 459-470.
    • (2008) J. Cell. Mol. Med. , vol.12 , Issue.2 , pp. 459-470
    • Widera, D.1    Kaus, A.2    Kaltschmidt, C.3    Kaltschmidt, B.4
  • 91
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • Friedman, S.L. Mechanisms of hepatic fibrogenesis. Gastroenterology, 2008, 134(6), 1655-1669.
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 92
    • 34548153747 scopus 로고    scopus 로고
    • How stem cells age and why this makes us grow old
    • Sharpless, N.E.; DePinho, R.A. How stem cells age and why this makes us grow old. Nat. Rev. Mol. Cell Biol., 2007, 8(9), 703-713.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , Issue.9 , pp. 703-713
    • Sharpless, N.E.1    Depinho, R.A.2
  • 94
    • 67650550499 scopus 로고    scopus 로고
    • Chronic inflammation, the tumor microenvironment and carcinogenesis
    • Gonda, T.A.; Tu, S.; Wang, T.C. Chronic inflammation, the tumor microenvironment and carcinogenesis. Cell Cycle, 2009, 8(13), 2005-2013.
    • (2009) Cell Cycle , vol.8 , Issue.13 , pp. 2005-2013
    • Gonda, T.A.1    Tu, S.2    Wang, T.C.3
  • 95
    • 51649120140 scopus 로고    scopus 로고
    • Review: Biological relevance of disseminated tumor cells in cancer patients
    • Riethdorf, S.; Wikman, H.; Pantel, K. Review: Biological relevance of disseminated tumor cells in cancer patients. Int. J. Cancer, 2008, 123(9), 1991-2006.
    • (2008) Int. J. Cancer , vol.123 , Issue.9 , pp. 1991-2006
    • Riethdorf, S.1    Wikman, H.2    Pantel, K.3
  • 97
    • 77950853025 scopus 로고    scopus 로고
    • New promising drug targets in cancerand metastasis-initiating cells
    • in press
    • Mimeault, M.; Batra, S.K. New promising drug targets in cancerand metastasis-initiating cells. Drug Discov. Today, 2010, (in press).
    • (2010) Drug Discov. Today
    • Mimeault, M.1    Batra, S.K.2
  • 98
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean, M.; Fojo, T.; Bates, S. Tumour stem cells and drug resistance. Nat. Rev. Cancer, 2005, 5(4), 275-284.
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 99
    • 34250306257 scopus 로고    scopus 로고
    • Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells
    • Ho, M.M.; Ng, A.V.; Lam, S.; Hung, J.Y. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells. Cancer Res., 2007, 67(10), 4827-4833.
    • (2007) Cancer Res. , vol.67 , Issue.10 , pp. 4827-4833
    • Ho, M.M.1    Ng, A.V.2    Lam, S.3    Hung, J.Y.4
  • 102
    • 36248961179 scopus 로고    scopus 로고
    • Tumorigenesis of chemotherapeutic drugresistant cancer stem-like cells in brain glioma
    • Kang, M.K.; Kang, S.K. Tumorigenesis of chemotherapeutic drugresistant cancer stem-like cells in brain glioma. Stem Cells Dev., 2007, 16(5), 837-847.
    • (2007) Stem Cells Dev. , vol.16 , Issue.5 , pp. 837-847
    • Kang, M.K.1    Kang, S.K.2
  • 103
    • 58149232517 scopus 로고    scopus 로고
    • Recent advances on the development of novel anti-cancer drugs targeting cancer stem/progenitor cells
    • Mimeault, M.; Batra, S.K. Recent advances on the development of novel anti-cancer drugs targeting cancer stem/progenitor cells. Drug Dev. Res., 2008, 69(7), 415-430.
    • (2008) Drug Dev. Res. , vol.69 , Issue.7 , pp. 415-430
    • Mimeault, M.1    Batra, S.K.2
  • 104
    • 45949101159 scopus 로고    scopus 로고
    • Expression of multidrug resistance genes in normal and cancer stem cells
    • Shervington, A.; Lu, C. Expression of multidrug resistance genes in normal and cancer stem cells. Cancer Invest., 2008, 26(5), 535-542.
    • (2008) Cancer Invest. , vol.26 , Issue.5 , pp. 535-542
    • Shervington, A.1    Lu, C.2
  • 105
    • 34247486847 scopus 로고    scopus 로고
    • High tolerance to apoptotic stimuli induced by serum depletion and ceramide in side-population cells: High expression of CD55 as a novel character for side-population
    • Xu, J.X.; Morii, E.; Liu, Y.; Nakamichi, N.; Ikeda, J.; Kimura, H.; Aozasa, K. High tolerance to apoptotic stimuli induced by serum depletion and ceramide in side-population cells: high expression of CD55 as a novel character for side-population. Exp. Cell Res., 2007, 313(9), 1877-1885.
    • (2007) Exp. Cell Res. , vol.313 , Issue.9 , pp. 1877-1885
    • Xu, J.X.1    Morii, E.2    Liu, Y.3    Nakamichi, N.4    Ikeda, J.5    Kimura, H.6    Aozasa, K.7
  • 107
    • 75949101677 scopus 로고    scopus 로고
    • ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome
    • Li, T.; Su, Y.; Mei, Y.; Leng, Q.; Leng, B.; Liu, Z.; Stass, S.A.; Jiang, F. ALDH1A1 is a marker for malignant prostate stem cells and predictor of prostate cancer patients' outcome. Lab. Invest., 2010, 90(2), 234-244.
    • (2010) Lab. Invest. , vol.90 , Issue.2 , pp. 234-244
    • Li, T.1    Su, Y.2    Mei, Y.3    Leng, Q.4    Leng, B.5    Liu, Z.6    Stass, S.A.7    Jiang, F.8
  • 108
    • 58049201990 scopus 로고    scopus 로고
    • The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma
    • Rappa, G.; Fodstad, O.; Lorico, A. The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma. Stem Cells, 2008, 26(12), 3008-3017.
    • (2008) Stem Cells , vol.26 , Issue.12 , pp. 3008-3017
    • Rappa, G.1    Fodstad, O.2    Lorico, A.3
  • 109
    • 70350362332 scopus 로고    scopus 로고
    • Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells
    • Yao, J.; Zhang, T.; Ren, J.; Yu, M.; Wu, G. Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells. Oncol. Rep., 2009, 22(4), 781-787.
    • (2009) Oncol. Rep. , vol.22 , Issue.4 , pp. 781-787
    • Yao, J.1    Zhang, T.2    Ren, J.3    Yu, M.4    Wu, G.5
  • 110
    • 58149357568 scopus 로고    scopus 로고
    • Monoclonal antibody CC188 binds a carbohydrate epitope expressed on the surface of both colorectal cancer stem cells and their differentiated progeny
    • Xu, M.; Yuan, Y.; Xia, Y.; Achilefu, S. Monoclonal antibody CC188 binds a carbohydrate epitope expressed on the surface of both colorectal cancer stem cells and their differentiated progeny. Clin. Cancer Res., 2008, 14(22), 7461-7469.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.22 , pp. 7461-7469
    • Xu, M.1    Yuan, Y.2    Xia, Y.3    Achilefu, S.4
  • 111
    • 33845951437 scopus 로고    scopus 로고
    • Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells
    • Misra, S.; Toole, B.P.; Ghatak, S. Hyaluronan constitutively regulates activation of multiple receptor tyrosine kinases in epithelial and carcinoma cells. J. Biol. Chem., 2006, 281(46), 34936-34941.
    • (2006) J. Biol. Chem. , vol.281 , Issue.46 , pp. 34936-34941
    • Misra, S.1    Toole, B.P.2    Ghatak, S.3
  • 112
    • 0037063999 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway
    • Ghatak, S.; Misra, S.; Toole, B.P. Hyaluronan oligosaccharides inhibit anchorage-independent growth of tumor cells by suppressing the phosphoinositide 3-kinase/Akt cell survival pathway. J. Biol. Chem., 2002, 277(41), 38013-38020.
    • (2002) J. Biol. Chem. , vol.277 , Issue.41 , pp. 38013-38020
    • Ghatak, S.1    Misra, S.2    Toole, B.P.3
  • 113
    • 47749116454 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
    • Bourguignon, L.Y.; Peyrollier, K.; Xia, W.; Gilad, E. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J. Biol. Chem., 2008, 283(25), 17635-17651.
    • (2008) J. Biol. Chem. , vol.283 , Issue.25 , pp. 17635-17651
    • Bourguignon, L.Y.1    Peyrollier, K.2    Xia, W.3    Gilad, E.4
  • 115
    • 77949674648 scopus 로고    scopus 로고
    • Cytotoxic effects induced by docetaxel, gefitinib and cyclopamine on side population and non-side population cell fractions from human invasive prostate cancer cells
    • in press
    • Mimeault, M.; Johansson, S.L.; Henichart, J.P.; Depreux, P.; Batra, S.K. Cytotoxic effects induced by docetaxel, gefitinib and cyclopamine on side population and non-side population cell fractions from human invasive prostate cancer cells. Mol. Cancer Ther., 2010, (in press).
    • (2010) Mol. Cancer Ther.
    • Mimeault, M.1    Johansson, S.L.2    Henichart, J.P.3    Depreux, P.4    Batra, S.K.5
  • 121
    • 38649109498 scopus 로고    scopus 로고
    • Molecular-targeted therapies: Lessons from years of clinical development
    • Rosa, D.D.; Ismael, G.; Lago, L.D.; Awada, A. Molecular-targeted therapies: lessons from years of clinical development. Cancer Treat. Rev., 2008, 34(1), 61-80.
    • (2008) Cancer Treat. Rev. , vol.34 , Issue.1 , pp. 61-80
    • Rosa, D.D.1    Ismael, G.2    Lago, L.D.3    Awada, A.4
  • 122
    • 44449117461 scopus 로고    scopus 로고
    • Lapatinib study supports cancer stem cell hypothesis, encourages industry research
    • Schmidt, C. Lapatinib study supports cancer stem cell hypothesis, encourages industry research. J. Natl. Cancer Inst., 2008, 100(10), 694-695.
    • (2008) J. Natl. Cancer Inst. , vol.100 , Issue.10 , pp. 694-695
    • Schmidt, C.1
  • 123
    • 48849085637 scopus 로고    scopus 로고
    • Allelic imbalances of the egfr gene as key events in breast cancer progression--the concept of committed progenitor cells
    • Agelopoulos, K.; Buerger, H.; Brandt, B. Allelic imbalances of the egfr gene as key events in breast cancer progression--the concept of committed progenitor cells. Curr. Cancer Drug Targets, 2008, 8(5), 431-445.
    • (2008) Curr. Cancer Drug Targets , vol.8 , Issue.5 , pp. 431-445
    • Agelopoulos, K.1    Buerger, H.2    Brandt, B.3
  • 126
    • 67650912118 scopus 로고    scopus 로고
    • The Hedgehog signaling pathway plays an essential role in maintaining the CD44+CD24-/low subpopulation and the side population of breast cancer cells
    • Tanaka, H.; Nakamura, M.; Kameda, C.; Kubo, M.; Sato, N.; Kuroki, S.; Tanaka, M.; Katano, M. The Hedgehog signaling pathway plays an essential role in maintaining the CD44+CD24-/low subpopulation and the side population of breast cancer cells. Anticancer Res., 2009, 29(6), 2147-2157.
    • (2009) Anticancer Res. , vol.29 , Issue.6 , pp. 2147-2157
    • Tanaka, H.1    Nakamura, M.2    Kameda, C.3    Kubo, M.4    Sato, N.5    Kuroki, S.6    Tanaka, M.7    Katano, M.8
  • 127
    • 33751549095 scopus 로고    scopus 로고
    • Targeting the Hedgehog pathway in cancer
    • Rubin, L.L.; de Sauvage, F.J. Targeting the Hedgehog pathway in cancer. Nat. Rev. Drug Discov. 2006, 5(12), 1026-1033.
    • (2006) Nat. Rev. Drug Discov. , vol.5 , Issue.12 , pp. 1026-1033
    • Rubin, L.L.1    De Sauvage, F.J.2
  • 128
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
    • Clement, V.; Sanchez, P.; de Tribolet N.; Radovanovic, I.; Altaba, A. HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Curr. Biol., 2007, 17(2), 165-172.
    • (2007) Curr. Biol. , vol.17 , Issue.2 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    De Tribolet, N.3    Radovanovic, I.4    Altaba, A.5
  • 130
    • 34547913091 scopus 로고    scopus 로고
    • Stem cells -- A revolution in therapeutics--Recent advances on the stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies
    • Mimeault, M.; Hauke, R.; Batra, S.K. Stem cells -- A revolution in therapeutics--Recent advances on the stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies. Clin. Pharmacol. Ther., 2007, 82(3), 252-264.
    • (2007) Clin. Pharmacol. Ther. , vol.82 , Issue.3 , pp. 252-264
    • Mimeault, M.1    Hauke, R.2    Batra, S.K.3
  • 131
    • 72949120937 scopus 로고    scopus 로고
    • Stem cell applications in disease research: Recent advances on stem cell and cancer stem cell biology and their therapeutic implications
    • Faraday, A.V. and Dyer, J.T., Eds.; NOVA Publisher, New York
    • Mimeault, M.; Batra, S.K. Stem Cell Applications in Disease Research: Recent Advances on Stem Cell and Cancer Stem Cell Biology and their Therapeutic Implications. In Progress in Stem Cell Applications; Faraday, A.V. and Dyer, J.T., Eds.; NOVA Publisher, New York: 2008; pp. 57-98.
    • (2008) Progress in Stem Cell Applications , pp. 57-98
    • Mimeault, M.1    Batra, S.K.2
  • 132
    • 33750592790 scopus 로고    scopus 로고
    • Recent advances on the significance of stem cells in tissue regeneration and cancer therapies
    • Mimeault, M.; Batra, S.K. Recent advances on the significance of stem cells in tissue regeneration and cancer therapies. Stem Cells, 2006, 24(11), 2319-2345.
    • (2006) Stem Cells , vol.24 , Issue.11 , pp. 2319-2345
    • Mimeault, M.1    Batra, S.K.2
  • 133
    • 24644493315 scopus 로고    scopus 로고
    • Cripto-1: A multifunctional modulator during embryogenesis and oncogenesis
    • Strizzi, L.; Bianco, C.; Normanno, N.; Salomon, D. Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis. Oncogene, 2005, 24(37), 5731-5741.
    • (2005) Oncogene , vol.24 , Issue.37 , pp. 5731-5741
    • Strizzi, L.1    Bianco, C.2    Normanno, N.3    Salomon, D.4
  • 134
    • 18144371250 scopus 로고    scopus 로고
    • Cripto as a target for cancer immunotherapy
    • Hu, X.F.; Xing, P.X. Cripto as a target for cancer immunotherapy. Expert Opin. Ther. Targets, 2005, 9(2), 383-394.
    • (2005) Expert Opin. Ther. Targets , vol.9 , Issue.2 , pp. 383-394
    • Hu, X.F.1    Xing, P.X.2
  • 136
    • 70349912085 scopus 로고    scopus 로고
    • Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: Implications for drug resistance and in vitro drug screening models
    • Sabisz, M.; Skladanowski, A. Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening models. Cell Cycle, 2009, 8(19), 3208-3217.
    • (2009) Cell Cycle , vol.8 , Issue.19 , pp. 3208-3217
    • Sabisz, M.1    Skladanowski, A.2
  • 138
    • 57349094741 scopus 로고    scopus 로고
    • Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling
    • Hu, C.; Li, H.; Li, J.; Zhu, Z.; Yin, S.; Hao, X.; Yao, M.; Zheng, S.; Gu, J. Analysis of ABCG2 expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling. Carcinogenesis, 2008, 29(12), 2289-2297.
    • (2008) Carcinogenesis , vol.29 , Issue.12 , pp. 2289-2297
    • Hu, C.1    Li, H.2    Li, J.3    Zhu, Z.4    Yin, S.5    Hao, X.6    Yao, M.7    Zheng, S.8    Gu, J.9
  • 139
    • 34249878632 scopus 로고    scopus 로고
    • Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport
    • Sims-Mourtada, J.; Izzo, J.G.; Ajani, J.; Chao, K.S. Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport. Oncogene, 2007, 26, 5674-5679.
    • (2007) Oncogene , vol.26 , pp. 5674-5679
    • Sims-Mourtada, J.1    Izzo, J.G.2    Ajani, J.3    Chao, K.S.4
  • 140
    • 53549119511 scopus 로고    scopus 로고
    • NFkappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells
    • Zhou, J.; Zhang, H.; Gu, P.; Bai, J.; Margolick, J.B.; Zhang, Y. NFkappaB pathway inhibitors preferentially inhibit breast cancer stem-like cells. Breast Cancer Res. Treat., 2007, 29, 909-912.
    • (2007) Breast Cancer Res. Treat. , vol.29 , pp. 909-912
    • Zhou, J.1    Zhang, H.2    Gu, P.3    Bai, J.4    Margolick, J.B.5    Zhang, Y.6
  • 145
    • 2942691389 scopus 로고    scopus 로고
    • Stem cell origin of cancer and differentiation therapy
    • Sell, S. Stem cell origin of cancer and differentiation therapy. Crit. Rev. Oncol. Hematol., 2004, 51(1), 1-28.
    • (2004) Crit. Rev. Oncol. Hematol. , vol.51 , Issue.1 , pp. 1-28
    • Sell, S.1
  • 146
    • 33750584024 scopus 로고    scopus 로고
    • Tumour stem cell-targeted treatment: Elimination or differentiation
    • Massard, C.; Deutsch, E.; Soria, J.C. Tumour stem cell-targeted treatment: elimination or differentiation. Ann. Oncol., 2006, 17(11), 1620-1624.
    • (2006) Ann. Oncol. , vol.17 , Issue.11 , pp. 1620-1624
    • Massard, C.1    Deutsch, E.2    Soria, J.C.3
  • 147
    • 34447301799 scopus 로고    scopus 로고
    • New agents for treatment of advanced transitional cell carcinoma
    • Perabo, F.G.; Muller, S.C. New agents for treatment of advanced transitional cell carcinoma. Ann. Oncol., 2006, 18(5), 835-843.
    • (2006) Ann. Oncol. , vol.18 , Issue.5 , pp. 835-843
    • Perabo, F.G.1    Muller, S.C.2
  • 149
    • 84862740746 scopus 로고    scopus 로고
    • The combination of 5-Fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells
    • Huang, C.; Zhang, X.M.; Tavaluc, R.T.; Hart, L.S.; Dicker, D.T.; Wang, W.; El-Deiry, W.S. The combination of 5-Fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells. Cancer Biol. Ther., 2009, 8(22), 2186-2193.
    • (2009) Cancer Biol. Ther. , vol.8 , Issue.22 , pp. 2186-2193
    • Huang, C.1    Zhang, X.M.2    Tavaluc, R.T.3    Hart, L.S.4    Dicker, D.T.5    Wang, W.6    El-Deiry, W.S.7
  • 150
    • 53949090314 scopus 로고    scopus 로고
    • Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres
    • Ji, Q.; Hao, X.; Meng, Y.; Zhang, M.; Desano, J.; Fan, D.; Xu, L. Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres. BMC Cancer, 2008, 8, 266.
    • (2008) BMC Cancer , vol.8 , pp. 266
    • Ji, Q.1    Hao, X.2    Meng, Y.3    Zhang, M.4    Desano, J.5    Fan, D.6    Xu, L.7
  • 153
    • 70449429426 scopus 로고    scopus 로고
    • Targeting tumor stroma using engineered mesenchymal stem cells reduces the growth of pancreatic carcinoma
    • Zischek, C.; Niess, H.; Ischenko, I.; Conrad, C.; Huss, R.; Jauch, K.W.; Nelson, P.J.; Bruns, C. Targeting tumor stroma using engineered mesenchymal stem cells reduces the growth of pancreatic carcinoma. Ann. Surg., 2009, 250(5), 747-753.
    • (2009) Ann. Surg. , vol.250 , Issue.5 , pp. 747-753
    • Zischek, C.1    Niess, H.2    Ischenko, I.3    Conrad, C.4    Huss, R.5    Jauch, K.W.6    Nelson, P.J.7    Bruns, C.8
  • 155
    • 0036831559 scopus 로고    scopus 로고
    • Vascular and haematopoietic stem cells: Novel targets for anti-angiogenesis therapy?
    • Rafii, S.; Lyden, D.; Benezra, R.; Hattori, K.; Heissig, B. Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy? Nat. Rev. Cancer, 2002, 2(11), 826-835.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.11 , pp. 826-835
    • Rafii, S.1    Lyden, D.2    Benezra, R.3    Hattori, K.4    Heissig, B.5
  • 156
    • 0034813202 scopus 로고    scopus 로고
    • Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice
    • Davidoff, A.M.; Ng, C.Y.; Brown, P.; Leary, M.A.; Spurbeck, W.W.; Zhou, J.; Horwitz, E.; Vanin, E.F.; Nienhuis, A.W. Bone marrow-derived cells contribute to tumor neovasculature and, when modified to express an angiogenesis inhibitor, can restrict tumor growth in mice. Clin. Cancer Res., 2001, 7(9), 2870-2879.
    • (2001) Clin. Cancer Res. , vol.7 , Issue.9 , pp. 2870-2879
    • Davidoff, A.M.1    Ng, C.Y.2    Brown, P.3    Leary, M.A.4    Spurbeck, W.W.5    Zhou, J.6    Horwitz, E.7    Vanin, E.F.8    Nienhuis, A.W.9
  • 157
    • 66249083525 scopus 로고    scopus 로고
    • Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer
    • Loebinger, M.R.; Eddaoudi, A.; Davies, D.; Janes, S.M. Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. Cancer Res., 2009, 69(10), 4134-4142.
    • (2009) Cancer Res. , vol.69 , Issue.10 , pp. 4134-4142
    • Loebinger, M.R.1    Eddaoudi, A.2    Davies, D.3    Janes, S.M.4
  • 158
    • 29844443964 scopus 로고    scopus 로고
    • Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies
    • Mimeault, M.; Batra, S.K. Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies. Carcinogenesis, 2006, 27, 1-22.
    • (2006) Carcinogenesis , vol.27 , pp. 1-22
    • Mimeault, M.1    Batra, S.K.2
  • 159
    • 3843052772 scopus 로고    scopus 로고
    • Pathological and molecular mechanisms of prostate carcinogenesis: Implications for diagnosis, detection, prevention, and treatment
    • De Marzo, A.M.; DeWeese, T.L.; Platz, E.A.; Meeker, A.K.; Nakayama, M.; Epstein, J.I.; Isaacs, W.B.; Nelson, W.G. Pathological and molecular mechanisms of prostate carcinogenesis: implications for diagnosis, detection, prevention, and treatment. J. Cell Biochem., 2004, 91(3), 459-477.
    • (2004) J. Cell Biochem. , vol.91 , Issue.3 , pp. 459-477
    • De Marzo, A.M.1    Deweese, T.L.2    Platz, E.A.3    Meeker, A.K.4    Nakayama, M.5    Epstein, J.I.6    Isaacs, W.B.7    Nelson, W.G.8
  • 160
    • 33749019746 scopus 로고    scopus 로고
    • Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells
    • Litvinov, I.V.; Vander Griend, D.J.; Xu, Y.; Antony, L.; Dalrymple, S.L.; Isaacs, J.T. Low-calcium serum-free defined medium selects for growth of normal prostatic epithelial stem cells. Cancer Res., 2006, 66(17), 8598-8607.
    • (2006) Cancer Res. , vol.66 , Issue.17 , pp. 8598-8607
    • Litvinov, I.V.1    Vander Griend, D.J.2    Xu, Y.3    Antony, L.4    Dalrymple, S.L.5    Isaacs, J.T.6
  • 161
    • 34247862433 scopus 로고    scopus 로고
    • Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis
    • Chen, B.Y.; Liu, J.Y.; Chang, H.H.; Chang, C.P.; Lo, W.Y.; Kuo, W.H.; Yang, C.R.; Lin, D.P. Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis. Biochem. Biophys. Res. Commun., 2007, 357(4), 1084-1089.
    • (2007) Biochem. Biophys. Res. Commun. , vol.357 , Issue.4 , pp. 1084-1089
    • Chen, B.Y.1    Liu, J.Y.2    Chang, H.H.3    Chang, C.P.4    Lo, W.Y.5    Kuo, W.H.6    Yang, C.R.7    Lin, D.P.8
  • 163
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins, A.T.; Berry, P.A.; Hyde, C.; Stower, M.J.; Maitland, N.J. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res., 2005, 65(23), 10946-10951.
    • (2005) Cancer Res. , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 164
    • 33646906851 scopus 로고    scopus 로고
    • Prostate cancer stem cells
    • Collins, A.T.; Maitland, N.J. Prostate cancer stem cells. Eur. J. Cancer, 2006, 42(12), 1213-1218.
    • (2006) Eur. J. Cancer , vol.42 , Issue.12 , pp. 1213-1218
    • Collins, A.T.1    Maitland, N.J.2
  • 165
    • 33751178827 scopus 로고    scopus 로고
    • Stem cells in prostate cancer: Resolving the castrate-resistant conundrum and implications for hormonal therapy
    • Sharifi, N.; Kawasaki, B.T.; Hurt, E.M.; Farrar, W.L. Stem cells in prostate cancer: Resolving the castrate-resistant conundrum and implications for hormonal therapy. Cancer Biol. Ther., 2006, 5(8), 901-906.
    • (2006) Cancer Biol. Ther. , vol.5 , Issue.8 , pp. 901-906
    • Sharifi, N.1    Kawasaki, B.T.2    Hurt, E.M.3    Farrar, W.L.4
  • 166
    • 33646475297 scopus 로고    scopus 로고
    • Mechanisms leading to the development of hormone-resistant prostate cancer
    • Kasper, S.; Cookson, M.S. Mechanisms leading to the development of hormone-resistant prostate cancer. Urol. Clin. North Am., 2006, 33(2), 201-210.
    • (2006) Urol. Clin. North Am. , vol.33 , Issue.2 , pp. 201-210
    • Kasper, S.1    Cookson, M.S.2
  • 167
    • 33644747185 scopus 로고    scopus 로고
    • Stem cells in prostate and prostate cancer development
    • Lam, J.S.; Reiter, R.E. Stem cells in prostate and prostate cancer development. Urol. Oncol., 2006, 24(2), 131-140.
    • (2006) Urol. Oncol. , vol.24 , Issue.2 , pp. 131-140
    • Lam, J.S.1    Reiter, R.E.2
  • 168
    • 34248140257 scopus 로고    scopus 로고
    • Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumorderived human prostate epithelial cell lines and in prostate cancer specimens
    • Miki, J.; Furusato, B.; Li, H.; Gu, Y.; Takahashi, H.; Egawa, S.; Sesterhenn, I.A.; McLeod, D.G.; Srivastava, S.; Rhim, J.S. Identification of putative stem cell markers, CD133 and CXCR4, in hTERT-immortalized primary nonmalignant and malignant tumorderived human prostate epithelial cell lines and in prostate cancer specimens. Cancer Res., 2007, 67(7), 3153-3161.
    • (2007) Cancer Res. , vol.67 , Issue.7 , pp. 3153-3161
    • Miki, J.1    Furusato, B.2    Li, H.3    Gu, Y.4    Takahashi, H.5    Egawa, S.6    Sesterhenn, I.A.7    McLeod, D.G.8    Srivastava, S.9    Rhim, J.S.10
  • 169
    • 58249117794 scopus 로고    scopus 로고
    • Genomic analysis of prostate cancer stem cells isolated from a highly metastatic cell line
    • Rowehl, R.A.; Crawford, H.; Dufour, A.; Ju, J.; Botchkina, G.I. Genomic analysis of prostate cancer stem cells isolated from a highly metastatic cell line. Cancer Genomics, Proteomics, 2008, 5(6), 301-310.
    • (2008) Cancer Genomics, Proteomics , vol.5 , Issue.6 , pp. 301-310
    • Rowehl, R.A.1    Crawford, H.2    Dufour, A.3    Ju, J.4    Botchkina, G.I.5
  • 173
    • 34249295225 scopus 로고    scopus 로고
    • Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium
    • Ao, M.; Franco, O.E.; Park, D.; Raman, D.; Williams, K.; Hayward, S.W. Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic epithelium. Cancer Res., 2007, 67(9), 4244-4253.
    • (2007) Cancer Res. , vol.67 , Issue.9 , pp. 4244-4253
    • Ao, M.1    Franco, O.E.2    Park, D.3    Raman, D.4    Williams, K.5    Hayward, S.W.6
  • 174
    • 10344234761 scopus 로고    scopus 로고
    • Molecular insights into prostate cancer progression: The missing link of tumor microenvironment
    • Chung, L.W.; Baseman, A.; Assikis, V.; Zhau, H.E. Molecular insights into prostate cancer progression: the missing link of tumor microenvironment. J. Urol., 2005, 173(1), 10-20.
    • (2005) J. Urol. , vol.173 , Issue.1 , pp. 10-20
    • Chung, L.W.1    Baseman, A.2    Assikis, V.3    Zhau, H.E.4
  • 175
    • 28544437291 scopus 로고    scopus 로고
    • Prostate epithelial stem cells
    • Rizzo, S.; Attard, G.; Hudson, D.L. Prostate epithelial stem cells. Cell Prolif., 2005, 38(6), 363-374.
    • (2005) Cell Prolif. , vol.38 , Issue.6 , pp. 363-374
    • Rizzo, S.1    Attard, G.2    Hudson, D.L.3
  • 176
    • 34548750381 scopus 로고    scopus 로고
    • Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations
    • Brown, M.D.; Gilmore, P.E.; Hart, C.A.; Samuel, J.D.; Ramani, V.A.; George, N.J.; Clarke, N.W. Characterization of benign and malignant prostate epithelial Hoechst 33342 side populations. Prostate, 2007, 67(13), 1384-1396.
    • (2007) Prostate , vol.67 , Issue.13 , pp. 1384-1396
    • Brown, M.D.1    Gilmore, P.E.2    Hart, C.A.3    Samuel, J.D.4    Ramani, V.A.5    George, N.J.6    Clarke, N.W.7
  • 178
    • 34547931301 scopus 로고    scopus 로고
    • The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population
    • Heer, R.; Robson, C.N.; Shenton, B.K.; Leung, H.Y. The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population. J. Cell Physiol., 2007, 212(3), 572-578.
    • (2007) J. Cell Physiol. , vol.212 , Issue.3 , pp. 572-578
    • Heer, R.1    Robson, C.N.2    Shenton, B.K.3    Leung, H.Y.4
  • 181
    • 33846982536 scopus 로고    scopus 로고
    • TGFBR3 loss and consequences in prostate cancer
    • Sharifi, N.; Hurt, E.M.; Kawasaki, B.T.; Farrar, W.L. TGFBR3 loss and consequences in prostate cancer. Prostate, 2007, 67(3), 301-311.
    • (2007) Prostate , vol.67 , Issue.3 , pp. 301-311
    • Sharifi, N.1    Hurt, E.M.2    Kawasaki, B.T.3    Farrar, W.L.4
  • 182
    • 65949098643 scopus 로고    scopus 로고
    • ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostate
    • Mathew, G.; Timm, E.A.; Jr. Sotomayor, P.; Godoy, A.; Montecinos, V.P.; Smith, G.J.; Huss, W.J. ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostate. Cell Cycle, 2009, 8(7), 1053-1061.
    • (2009) Cell Cycle , vol.8 , Issue.7 , pp. 1053-1061
    • Mathew, G.1    Timm, E.A.2    Jr. Sotomayor, P.3    Godoy, A.4    Montecinos, V.P.5    Smith, G.J.6    Huss, W.J.7
  • 184
    • 31944448885 scopus 로고    scopus 로고
    • Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
    • Wang, S.; Garcia, A.J.; Wu, M.; Lawson, D.A.; Witte, O.N.; Wu, H. Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation. Proc. Natl. Acad. Sci. USA, 2006, 103(5), 1480-1485.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , Issue.5 , pp. 1480-1485
    • Wang, S.1    Garcia, A.J.2    Wu, M.3    Lawson, D.A.4    Witte, O.N.5    Wu, H.6
  • 185
    • 34250822389 scopus 로고    scopus 로고
    • Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts
    • Zhou, Z.; Flesken-Nikitin, A.; Nikitin, A.Y. Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts. Cancer Res., 2007, 67(12), 5683-5690.
    • (2007) Cancer Res. , vol.67 , Issue.12 , pp. 5683-5690
    • Zhou, Z.1    Flesken-Nikitin, A.2    Nikitin, A.Y.3
  • 186
    • 37349003357 scopus 로고    scopus 로고
    • Focal degeneration of basal cells and the resultant auto-immunoreactions: A novel mechanism for prostate tumor progression and invasion
    • Man, Y.G.; Gardner, W.A. Focal degeneration of basal cells and the resultant auto-immunoreactions: A novel mechanism for prostate tumor progression and invasion. Med. Hypotheses, 2007, 70(2), 387-408.
    • (2007) Med. Hypotheses , vol.70 , Issue.2 , pp. 387-408
    • Man, Y.G.1    Gardner, W.A.2
  • 187
    • 0038758829 scopus 로고    scopus 로고
    • New advances on prostate carcinogenesis and therapies: Involvement of EGF-EGFR transduction system
    • Mimeault, M.; Pommery, N.; Henichart, J.P. New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system. Growth Factors, 2003, 21(1), 1-14.
    • (2003) Growth Factors , vol.21 , Issue.1 , pp. 1-14
    • Mimeault, M.1    Pommery, N.2    Henichart, J.P.3
  • 188
    • 33745885674 scopus 로고    scopus 로고
    • STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines
    • Zhou, W.; Grandis, J.R.; Wells, A. STAT3 is required but not sufficient for EGF receptor-mediated migration and invasion of human prostate carcinoma cell lines. Br. J. Cancer, 2006, 95(2), 164-171.
    • (2006) Br. J. Cancer , vol.95 , Issue.2 , pp. 164-171
    • Zhou, W.1    Grandis, J.R.2    Wells, A.3
  • 189
    • 33748460152 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: Correlation with androgen independence
    • Shah, R.B.; Ghosh, D.; Elder, J.T. Epidermal growth factor receptor (ErbB1) expression in prostate cancer progression: correlation with androgen independence. Prostate, 2006, 66(13), 1437-1444.
    • (2006) Prostate , vol.66 , Issue.13 , pp. 1437-1444
    • Shah, R.B.1    Ghosh, D.2    Elder, J.T.3
  • 190
    • 26944443648 scopus 로고    scopus 로고
    • The mechanisms and managements of hormone-therapy resistance in breast and prostate cancers
    • Rau, K.M.; Kang, H.Y.; Cha, T.L.; Miller, S.A.; Hung, M.C. The mechanisms and managements of hormone-therapy resistance in breast and prostate cancers. Endocr. Relat. Cancer, 2005, 12(3), 511-532.
    • (2005) Endocr. Relat. Cancer , vol.12 , Issue.3 , pp. 511-532
    • Rau, K.M.1    Kang, H.Y.2    Cha, T.L.3    Miller, S.A.4    Hung, M.C.5
  • 191
    • 33646244023 scopus 로고    scopus 로고
    • Hormone refractory prostate cancer (HRPC): Present and future approaches of therapy
    • Di Lorenzo, G.; De Placido, S. Hormone refractory prostate cancer (HRPC): present and future approaches of therapy. Int. J. Immunopathol. Pharmacol., 2006, 19(1), 11-34.
    • (2006) Int. J. Immunopathol. Pharmacol. , vol.19 , Issue.1 , pp. 11-34
    • Di Lorenzo, G.1    De Placido, S.2
  • 192
    • 33747469939 scopus 로고    scopus 로고
    • Non-hormonal systemic therapy in men with hormonerefractory prostate cancer and metastases: A systematic review from the cancer care ontario program in evidence-based care's genitourinary cancer disease site group
    • Winquist, E.; Waldron, T.; Berry, S.; Ernst, D.S.; Hotte, S.; Lukka, H. Non-hormonal systemic therapy in men with hormonerefractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group. BMC. Cancer, 2006, 6(1), 112.
    • (2006) BMC. Cancer , vol.6 , Issue.1 , pp. 112
    • Winquist, E.1    Waldron, T.2    Berry, S.3    Ernst, D.S.4    Hotte, S.5    Lukka, H.6
  • 195
    • 18844368532 scopus 로고    scopus 로고
    • Interference with HH-GLI signaling inhibits prostate cancer
    • Stecca, B.; Mas, C.; Altaba, A.R. Interference with HH-GLI signaling inhibits prostate cancer. Trends Mol. Med., 2005, 11(5), 199-203.
    • (2005) Trends Mol. Med. , vol.11 , Issue.5 , pp. 199-203
    • Stecca, B.1    Mas, C.2    Altaba, A.R.3
  • 196
    • 33645083201 scopus 로고    scopus 로고
    • Sonic Hedgehog signaling in advanced prostate cancer
    • Datta, S.; Datta, M.W. Sonic Hedgehog signaling in advanced prostate cancer. Cell Mol. Life Sci., 2006, 63(4), 435-448.
    • (2006) Cell Mol. Life Sci. , vol.63 , Issue.4 , pp. 435-448
    • Datta, S.1    Datta, M.W.2
  • 198
    • 67649948804 scopus 로고    scopus 로고
    • WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics
    • Bisson, I.; Prowse, D.M. WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics. Cell Res., 2009, 19(6), 683-697.
    • (2009) Cell Res. , vol.19 , Issue.6 , pp. 683-697
    • Bisson, I.1    Prowse, D.M.2
  • 199
    • 70449721175 scopus 로고    scopus 로고
    • Characterization of non-malignant and malignant prostatic stem/progenitor cells by Hoecsht side population method
    • Mimeault, M.; Batra, S.K. Characterization of non-malignant and malignant prostatic stem/progenitor cells by Hoecsht side population method. Methods Mol. Biol., 2009, 568, 139-149.
    • (2009) Methods Mol. Biol. , vol.568 , pp. 139-149
    • Mimeault, M.1    Batra, S.K.2
  • 200
    • 33745570865 scopus 로고    scopus 로고
    • Quality of life and pain in advanced stage prostate cancer: Results of a Southwest Oncology Group randomized trial comparing docetaxel and estramustine to mitoxantrone and prednisone
    • Berry, D.L.; Moinpour, C.M.; Jiang, C.S.; Ankerst, D.P.; Petrylak, D.P.; Vinson, L.V.; Lara, P.N.; Jones, S.; Taplin, M.E.; Burch, P.A.; Hussain, M.H.; Crawford, E.D. Quality of life and pain in advanced stage prostate cancer: results of a Southwest Oncology Group randomized trial comparing docetaxel and estramustine to mitoxantrone and prednisone. J. Clin. Oncol., 2006, 24(18), 2828-2835.
    • (2006) J. Clin. Oncol. , vol.24 , Issue.18 , pp. 2828-2835
    • Berry, D.L.1    Moinpour, C.M.2    Jiang, C.S.3    Ankerst, D.P.4    Petrylak, D.P.5    Vinson, L.V.6    Lara, P.N.7    Jones, S.8    Taplin, M.E.9    Burch, P.A.10    Hussain, M.H.11    Crawford, E.D.12
  • 202
    • 33751413048 scopus 로고    scopus 로고
    • Current indications for chemotherapy in prostate cancer patients
    • Calabro, F.; Sternberg, C.N. Current indications for chemotherapy in prostate cancer patients. Eur. Urol., 2007, 51(1), 17-26.
    • (2007) Eur. Urol. , vol.51 , Issue.1 , pp. 17-26
    • Calabro, F.1    Sternberg, C.N.2
  • 203
    • 34547681208 scopus 로고    scopus 로고
    • Castration resistant, taxane naive metastatic prostate cancer: Current clinical approaches and future directions
    • Gignac, G.A.; Morris, M.J.; Hussain, M. Castration resistant, taxane naive metastatic prostate cancer: Current clinical approaches and future directions. J. Urol., 2007, 178(3 Pt 2), S30-S35.
    • (2007) J. Urol. , vol.178 , Issue.3 PART 2
    • Gignac, G.A.1    Morris, M.J.2    Hussain, M.3
  • 205
    • 34347231279 scopus 로고    scopus 로고
    • Biology and clinical management of prostate cancer bone metastasis
    • Ye, X.C.; Choueiri, M.; Tu, S.M.; Lin, S.H. Biology and clinical management of prostate cancer bone metastasis. Front. Biosci., 2007, 12, 3273-3286.
    • (2007) Front. Biosci. , vol.12 , pp. 3273-3286
    • Ye, X.C.1    Choueiri, M.2    Tu, S.M.3    Lin, S.H.4
  • 206
    • 38849154330 scopus 로고    scopus 로고
    • Prostate cancer: Screening, diagnosis and management in 2007
    • Grubb, R.L.; III; Kibel, A.S. Prostate cancer: screening, diagnosis and management in 2007. Mol. Med., 2007, 104(5), 408-413.
    • (2007) Mol. Med. , vol.104 , Issue.5 , pp. 408-413
    • Grubb Iii, R.L.1    Kibel, A.S.2
  • 207
    • 58049196759 scopus 로고    scopus 로고
    • Mechanisms mediating androgen receptor reactivation after castration
    • Yuan, X.; Balk, S.P. Mechanisms mediating androgen receptor reactivation after castration. Urol. Oncol., 2009, 27(1), 36-41.
    • (2009) Urol. Oncol. , vol.27 , Issue.1 , pp. 36-41
    • Yuan, X.1    Balk, S.P.2
  • 209
    • 33746932180 scopus 로고    scopus 로고
    • Management of the spectrum of hormone refractory prostate cancer
    • Clarke, N.W. Management of the spectrum of hormone refractory prostate cancer. Eur. Urol., 2006, 50(3), 428-438.
    • (2006) Eur. Urol. , vol.50 , Issue.3 , pp. 428-438
    • Clarke, N.W.1
  • 210
    • 54949124918 scopus 로고    scopus 로고
    • Aging of the prostate epithelial stem/progenitor cell
    • Zenzmaier, C.; Untergasser, G.; Berger, P. Aging of the prostate epithelial stem/progenitor cell. Exp. Gerontol., 2008, 43(11), 981-985.
    • (2008) Exp. Gerontol. , vol.43 , Issue.11 , pp. 981-985
    • Zenzmaier, C.1    Untergasser, G.2    Berger, P.3
  • 211
    • 34250315214 scopus 로고    scopus 로고
    • Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo
    • Gu, G.; Yuan, J.; Wills, M.; Kasper, S. Prostate cancer cells with stem cell characteristics reconstitute the original human tumor in vivo. Cancer Res., 2007, 67(10), 4807-4815.
    • (2007) Cancer Res. , vol.67 , Issue.10 , pp. 4807-4815
    • Gu, G.1    Yuan, J.2    Wills, M.3    Kasper, S.4
  • 212
    • 42049121143 scopus 로고    scopus 로고
    • Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies against advanced prostate cancers
    • Mimeault, M.; Mehta, P.P.; Hauke, R.; Batra, S.K. Functions of normal and malignant prostatic stem/progenitor cells in tissue regeneration and cancer progression and novel targeting therapies against advanced prostate cancers. Endocr. Rev., 2008, 29(2), 234-252.
    • (2008) Endocr. Rev. , vol.29 , Issue.2 , pp. 234-252
    • Mimeault, M.1    Mehta, P.P.2    Hauke, R.3    Batra, S.K.4
  • 213
    • 17044420819 scopus 로고    scopus 로고
    • Selective reduction of estrogen receptor (ER) positive breast cancer occurrence by estrogen receptor modulators supports etiological distinction between ER positive and ER negative breast cancers
    • Kurbel, S. Selective reduction of estrogen receptor (ER) positive breast cancer occurrence by estrogen receptor modulators supports etiological distinction between ER positive and ER negative breast cancers. Med. Hypotheses, 2005, 64(6), 1182-1187.
    • (2005) Med. Hypotheses , vol.64 , Issue.6 , pp. 1182-1187
    • Kurbel, S.1
  • 214
    • 33749017910 scopus 로고    scopus 로고
    • Signaling pathways in self-renewing hematopoietic and leukemic stem cells: Do all stem cells need a niche?
    • Rizo, A.; Vellenga, E.; de Haan G.; Schuringa, J.J. Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche? Hum. Mol. Genet., 2006, 15(Spec No 2), R210-R219.
    • (2006) Hum. Mol. Genet. , vol.15 , Issue.SPEC NO 2
    • Rizo, A.1    Vellenga, E.2    De Haan, G.3    Schuringa, J.J.4
  • 215
    • 34247578315 scopus 로고    scopus 로고
    • ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance
    • de Jonge-Peeters, S.D.; Kuipers, F.; de Vries, E.G.; Vellenga, E. ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance. Crit. Rev. Oncol. Hematol., 2007, 62(3), 214-226.
    • (2007) Crit. Rev. Oncol. Hematol. , vol.62 , Issue.3 , pp. 214-226
    • De Jonge-Peeters, S.D.1    Kuipers, F.2    De Vries, E.G.3    Vellenga, E.4
  • 216
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • Beachy, P.A.; Karhadkar, S.S.; Berman, D.M. Tissue repair and stem cell renewal in carcinogenesis. Nature, 2004, 432(7015), 324-331.
    • (2004) Nature , vol.432 , Issue.7015 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 217
    • 42449161959 scopus 로고    scopus 로고
    • Recent advances on the molecular mechanisms involved in drug-resistance of cancer cells and novel targeting therapies
    • Mimeault, M.; Hauke, R.; Batra, S.K. Recent advances on the molecular mechanisms involved in drug-resistance of cancer cells and novel targeting therapies. Clin. Pharmacol. Ther., 2008, 83(5), 673-691.
    • (2008) Clin. Pharmacol. Ther. , vol.83 , Issue.5 , pp. 673-691
    • Mimeault, M.1    Hauke, R.2    Batra, S.K.3
  • 218
    • 50849090600 scopus 로고    scopus 로고
    • Recent progress on tissue-resident adult stem cell biology and their therapeutic implications
    • Mimeault, M.; Batra, S.K. Recent progress on tissue-resident adult stem cell biology and their therapeutic implications. Stem Cell Rev., 2008, 4(1), 27-49.
    • (2008) Stem Cell Rev. , vol.4 , Issue.1 , pp. 27-49
    • Mimeault, M.1    Batra, S.K.2
  • 219
    • 65549140597 scopus 로고    scopus 로고
    • Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach
    • Kawasaki, B.T.; Hurt, E.M.; Kalathur, M.; Duhagon, M.A.; Milner, J.A.; Kim, Y.S.; Farrar, W.L. Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach. Prostate, 2009, 69(8), 827-837.
    • (2009) Prostate , vol.69 , Issue.8 , pp. 827-837
    • Kawasaki, B.T.1    Hurt, E.M.2    Kalathur, M.3    Duhagon, M.A.4    Milner, J.A.5    Kim, Y.S.6    Farrar, W.L.7
  • 221
    • 34248372925 scopus 로고    scopus 로고
    • The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia
    • Carriere, C.; Seeley, E.S.; Goetze, T.; Longnecker, D.S.; Korc, M. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proc. Natl. Acad. Sci. U S.A., 2007, 104(11), 4437-4442.
    • (2007) Proc. Natl. Acad. Sci. U S.A. , vol.104 , Issue.11 , pp. 4437-4442
    • Carriere, C.1    Seeley, E.S.2    Goetze, T.3    Longnecker, D.S.4    Korc, M.5
  • 222
    • 33751209187 scopus 로고    scopus 로고
    • Hedgehog/Ras interactions regulate early stages of pancreatic cancer
    • Pasca di, M.M.; Sekine, S.; Ermilov, A.; Ferris, J.; Dlugosz, A.A.; Hebrok, M. Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev., 2006, 20(22), 3161-3173.
    • (2006) Genes Dev. , vol.20 , Issue.22 , pp. 3161-3173
    • Pasca Di, M.M.1    Sekine, S.2    Ermilov, A.3    Ferris, J.4    Dlugosz, A.A.5    Hebrok, M.6
  • 225
    • 33751209187 scopus 로고    scopus 로고
    • Hedgehog/Ras interactions regulate early stages of pancreatic cancer
    • Pasca di, M.M.; Sekine, S.; Ermilov, A.; Ferris, J.; Dlugosz, A.A.; Hebrok, M. Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev., 2006, 20(22), 3161-3173.
    • (2006) Genes Dev. , vol.20 , Issue.22 , pp. 3161-3173
    • Pasca Di, M.M.1    Sekine, S.2    Ermilov, A.3    Ferris, J.4    Dlugosz, A.A.5    Hebrok, M.6
  • 227
    • 34248228180 scopus 로고    scopus 로고
    • Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties
    • Gou, S.; Liu, T.; Wang, C.; Yin, T.; Li, K.; Yang, M.; Zhou, J. Establishment of clonal colony-forming assay for propagation of pancreatic cancer cells with stem cell properties. Pancreas, 2007, 34(4), 429-435.
    • (2007) Pancreas , vol.34 , Issue.4 , pp. 429-435
    • Gou, S.1    Liu, T.2    Wang, C.3    Yin, T.4    Li, K.5    Yang, M.6    Zhou, J.7
  • 229
    • 27644549557 scopus 로고    scopus 로고
    • Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies
    • Mimeault, M.; Brand, R.E.; Sasson, A.A.; Batra, S.K. Recent advances on the molecular mechanisms involved in pancreatic cancer progression and therapies. Pancreas, 2005, 31(4), 301-316.
    • (2005) Pancreas , vol.31 , Issue.4 , pp. 301-316
    • Mimeault, M.1    Brand, R.E.2    Sasson, A.A.3    Batra, S.K.4
  • 230
    • 67349117952 scopus 로고    scopus 로고
    • Treatment of advanced pancreatic cancer: From gemcitabine single agent to combinations and targeted therapy
    • Rivera, F.; Lopez-Tarruella, S.; Vega-Villegas, M.A.; Salcedo, M. Treatment of advanced pancreatic cancer: From gemcitabine single agent to combinations and targeted therapy. Cancer Treat. Rev., 2009, 35(4), 335-339.
    • (2009) Cancer Treat. Rev. , vol.35 , Issue.4 , pp. 335-339
    • Rivera, F.1    Lopez-Tarruella, S.2    Vega-Villegas, M.A.3    Salcedo, M.4
  • 231
    • 61449119672 scopus 로고    scopus 로고
    • Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer
    • El Maalouf G.; Le, T.C.; Batty, G.N.; Faivre, S.; Raymond, E. Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer. Cancer Treat. Rev., 2009, 35(2), 167-174.
    • (2009) Cancer Treat. Rev. , vol.35 , Issue.2 , pp. 167-174
    • El Maalouf, G.1    Le, T.C.2    Batty, G.N.3    Faivre, S.4    Raymond, E.5
  • 232
    • 34247569912 scopus 로고    scopus 로고
    • Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients
    • Bai, J.; Sata, N.; Nagai, H. Gene expression analysis for predicting gemcitabine sensitivity in pancreatic cancer patients. HPB (Oxford), 2007, 9(2), 150-155.
    • (2007) HPB (Oxford) , vol.9 , Issue.2 , pp. 150-155
    • Bai, J.1    Sata, N.2    Nagai, H.3
  • 233
    • 70349873330 scopus 로고    scopus 로고
    • CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells
    • Hong, S.P.; Wen, J.; Bang, S.; Park, S.; Song, S.Y. CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells. Int. J. Cancer, 2009, 125(10), 2323-2331.
    • (2009) Int. J. Cancer , vol.125 , Issue.10 , pp. 2323-2331
    • Hong, S.P.1    Wen, J.2    Bang, S.3    Park, S.4    Song, S.Y.5
  • 234
    • 69849110542 scopus 로고    scopus 로고
    • A side population of cells from a human pancreatic carcinoma cell line harbors cancer stem cell characteristics
    • Wang, Y.H.; Li, F.; Luo, B.; Wang, X.H.; Sun, H.C.; Liu, S.; Cui, Y.Q.; Xu, X.X. A side population of cells from a human pancreatic carcinoma cell line harbors cancer stem cell characteristics. Neoplasma, 2009, 56(5), 371-378.
    • (2009) Neoplasma , vol.56 , Issue.5 , pp. 371-378
    • Wang, Y.H.1    Li, F.2    Luo, B.3    Wang, X.H.4    Sun, H.C.5    Liu, S.6    Cui, Y.Q.7    Xu, X.X.8
  • 235
    • 77950828177 scopus 로고    scopus 로고
    • MUC4 down-regulation reverse chemoresistance of pancreatic cancer stem/progenitor cells and their progenies
    • in press
    • Mimeault, M.; Johansson, S.L.; Senapati, S.; Momi, N.; Chakraborty, S.; Batra, S.K. MUC4 down-regulation reverse chemoresistance of pancreatic cancer stem/progenitor cells and their progenies. Cancer Lett., 2010, (in press).
    • (2010) Cancer Lett.
    • Mimeault, M.1    Johansson, S.L.2    Senapati, S.3    Momi, N.4    Chakraborty, S.5    Batra, S.K.6
  • 237
    • 77954829252 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway is critical for survival and proliferation of pancreatic cancer stem-like side population cells
    • Zhou, J.; Wang, C.Y.; Liu, T.; Wu, H.S.; Zhou, F.; Xiong, J.X.; Zhao, G.; Yang, M.; Yin, T.; & Zhou, M.T. Phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway is critical for survival and proliferation of pancreatic cancer stem-like side population cells. Zhonghua Yi. Xue. Za Zhi., 2008, 88(42), 2994-2998.
    • (2008) Zhonghua Yi. Xue. Za Zhi. , vol.88 , Issue.42 , pp. 2994-2998
    • Zhou, J.1    Wang, C.Y.2    Liu, T.3    Wu, H.S.4    Zhou, F.5    Xiong, J.X.6    Zhao, G.7    Yang, M.8    Yin, T.9    Zhou, M.T.10
  • 239
    • 65549141305 scopus 로고    scopus 로고
    • Acquisition of epithelial-mesenchymal transition phenotype of gemcitabineresistant pancreatic cancer cells is linked with activation of the notch signaling pathway
    • Wang, Z.; Li, Y.; Kong, D.; Banerjee, S.; Ahmad, A.; Azmi, A.S.; Ali, S.; Abbruzzese, J.L.; Gallick, G.E.; arkar, F.H. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabineresistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res., 2009, 69(6), 2400-2407.
    • (2009) Cancer Res. , vol.69 , Issue.6 , pp. 2400-2407
    • Wang, Z.1    Li, Y.2    Kong, D.3    Banerjee, S.4    Ahmad, A.5    Azmi, A.S.6    Ali, S.7    Abbruzzese, J.L.8    Gallick, G.E.9    Arkar, F.H.10
  • 240
    • 75149117750 scopus 로고    scopus 로고
    • Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop
    • Levina, V.; Marrangoni, A.; Wang, T.; Parikh, S.; Su, Y.; Herberman, R.; Lokshin, A.; Gorelik, E. Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop. Cancer Res., 2009, 70(1), 338-346.
    • (2009) Cancer Res. , vol.70 , Issue.1 , pp. 338-346
    • Levina, V.1    Marrangoni, A.2    Wang, T.3    Parikh, S.4    Su, Y.5    Herberman, R.6    Lokshin, A.7    Gorelik, E.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.