Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation

Development

Volumn 127, Issue 8, 2000, Pages 1593-1605

  Park, H L ^a,b   Bai, C ^a   Platt, K A ^a,e   Matise, M P ^a   Beeghly, A ^a   Hui, C C ^c,d   Nakashima, M ^a,f   Joyner, A L ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e LEXICON PHARMACEUTICALS INC   (United States)

^f KYUSHU UNIVERSITY   (Japan)

Author keywords

Anteroposterior patterning; CNS; Gli1; Mouse; Polydactyly; Sonic Hedgehog

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DNA BINDING; EXON; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; LIMB DEVELOPMENT; MOUSE; MOUSE MUTANT; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PHENOTYPE; POLYDACTYLY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINAL CORD NERVE CELL; TRANSGENIC MOUSE;

ABNORMALITIES, MULTIPLE; ALLELES; ANIMALS; BINDING SITES; BRAIN; COS CELLS; DIENCEPHALON; DNA; DNA-BINDING PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; EXTREMITIES; GENE EXPRESSION; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LUNG; MICE; MICE, TRANSGENIC; MUTAGENESIS; NERVE TISSUE PROTEINS; NOTOCHORD; NUCLEAR PROTEINS; ONCOGENE PROTEINS; PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; SPINAL CORD; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; XENOPUS PROTEINS; ZINC FINGERS;

ANIMALIA; ERINACEIDAE; MAMMALIA; MUS MUSCULUS; VERTEBRATA;

EID: 0034055649     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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