-
1
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
DOI 10.1101/gad.938601
-
Ingham PW and McMahon AP: Hedgehog signaling in animal development: paradigms and principles. Genes Dev 15: 3059-3087, 2001. (Pubitemid 33115673)
-
(2001)
Genes and Development
, vol.15
, Issue.23
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
2
-
-
0036559186
-
Gli and hedgehog in cancer: Tumours, embryos and stem cells
-
Ruiz i Altaba A, Sanchez P and Dahmane N: Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer 2: 361-372, 2002. (Pubitemid 37328949)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.5
, pp. 361-372
-
-
Ruiz I, A.A.1
Sanchez, P.2
Dahmane, N.3
-
3
-
-
0035098013
-
An absolute requirement for Cubitus interruptus in Hedgehog signaling
-
Methot N and Basler K: An absolute requirement for Cubitus interruptus in Hedgehog signaling. Development 128: 733-742, 2001. (Pubitemid 32229250)
-
(2001)
Development
, vol.128
, Issue.5
, pp. 733-742
-
-
Methot, N.1
Basler, K.2
-
4
-
-
0242268525
-
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
-
DOI 10.1038/nature01972
-
Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gerstenblith MR, Briggs K, Parker AR, Shimada Y, Eshleman JR, Watkins DN and Beachy PA: Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425: 846-851, 2003. (Pubitemid 37351469)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 846-851
-
-
Berman, D.M.1
Karhadkar, S.S.2
Maitra, A.3
De Oca, R.M.4
Gerstenblith, M.R.5
Briggs, K.6
Parker, A.R.7
Shimada, Y.8
Eshleman, J.R.9
Watkins, D.N.10
Beachy, P.A.11
-
5
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
DOI 10.1038/nature02009
-
Thayer SP, di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, Lauwers GY, Qi YP, Gysin S, Fernandez-del Castillo C, Yajnik V, Antoniu B, McMahon M, Warshaw AL and Hebrok M: Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 425: 851-856, 2003. (Pubitemid 37355945)
-
(2003)
Nature
, vol.425
, Issue.6960
, pp. 851-856
-
-
Thayer, S.P.1
Di, M.M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del, C.C.9
Yajnik, V.10
Antoniu, B.11
McMahon, M.12
Warshaw, A.L.13
Hebrok, M.14
-
6
-
-
2942616380
-
Indian hedgehog signaling pathway: Expression and regulation in pancreatic cancer
-
DOI 10.1002/ijc.20194
-
Kayed H, Kleeff J, Keleg S, Guo J, Ketterer K, Berberat PO, Giese N, Esposito I, Giese T, Buchler MW and Friess H: Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer. Int J Cancer 110: 668-676, 2004. (Pubitemid 38746024)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.5
, pp. 668-676
-
-
Kayed, H.1
Kleeff, J.2
Keleg, S.3
Guo, J.4
Ketterer, K.5
Berberat, P.O.6
Giese, N.7
Esposito, I.8
Giese, T.9
Buchler, M.W.10
Friess, H.11
-
7
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
DOI 10.1038/nature01493
-
Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA and Baylin SB: Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422: 313-317, 2003. (Pubitemid 36378358)
-
(2003)
Nature
, vol.422
, Issue.6929
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
8
-
-
4344586961
-
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer
-
DOI 10.1158/0008-5472.CAN-04-0416
-
Kubo M, Nakamura M, Tasaki A, Yamanaka N, Nakashima H, Nomura M, Kuroki S and Katano M: Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer. Cancer Res 64: 6071-6074, 2004. (Pubitemid 39129406)
-
(2004)
Cancer Research
, vol.64
, Issue.17
, pp. 6071-6074
-
-
Kubo, M.1
Nakamura, M.2
Tasaki, A.3
Yamanaka, N.4
Nakashima, H.5
Nomura, M.6
Kuroki, S.7
Katano, M.8
-
9
-
-
4344659678
-
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
-
DOI 10.1073/pnas.0404956101
-
Sanchez P, Hernandez AM, Stecca B, Kahler AJ, DeGueme AM, Barrett A, Beyna M, Datta MW, Datta S and Ruiz i Altaba A: Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc Natl Acad Sci USA 101: 12561-12566, 2004. (Pubitemid 39122063)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.34
, pp. 12561-12566
-
-
Sanchez, P.1
Hernandez, A.M.2
Stecca, B.3
Kahler, A.J.4
DeGueme, A.M.5
Barrett, A.6
Beyna, M.7
Datta, M.W.8
Datta, S.9
Ruiz I, A.A.10
-
10
-
-
2942533929
-
Hedgehog signalling in colorectal tumour cells: Induction of apoptosis with cyclopamine treatment
-
DOI 10.1002/ijc.20227
-
Qualtrough D, Buda A, Gaffield W, Williams AC and Paraskeva C: Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Int J Cancer 110: 831-837, 2004. (Pubitemid 38758508)
-
(2004)
International Journal of Cancer
, vol.110
, Issue.6
, pp. 831-837
-
-
Qualtrough, D.1
Buda, A.2
Gaffield, W.3
Williams, A.C.4
Paraskeva, C.5
-
11
-
-
0034053069
-
Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus
-
DOI 10.1126/science.287.5458.1606
-
Peifer M and Polakis P: Wnt signaling in oncogenesis and embryogenesis - a look outside the nucleus. Science 287: 1606-1609, 2000. (Pubitemid 30127755)
-
(2000)
Science
, vol.287
, Issue.5458
, pp. 1606-1609
-
-
Peifer, M.1
Polakis, P.2
-
12
-
-
4344584730
-
WNT and β-catenin signalling: Diseases and therapies
-
DOI 10.1038/nrg1427
-
Moon RT, Kohn AD, De Ferrari GV and Kaykas A: WNT and β-catenin signalling: diseases and therapies. Nat Rev Genet 5: 691-701, 2004. (Pubitemid 39150127)
-
(2004)
Nature Reviews Genetics
, vol.5
, Issue.9
, pp. 691-701
-
-
Moon, R.T.1
Kohn, A.D.2
De Ferrari, G.V.3
Kaykas, A.4
-
13
-
-
3042665321
-
Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling
-
DOI 10.1038/sj.onc.1207605
-
Taylor MD, Zhang X, Liu L, Hui CC, Mainprize TG, Scherer SW, Wainwright B, Hogg D and Rutka JT: Failure of a medulloblastoma-derived mutant of SUFU to suppress WNT signaling. Oncogene 23: 4577-4583, 2004. (Pubitemid 38850405)
-
(2004)
Oncogene
, vol.23
, Issue.26
, pp. 4577-4583
-
-
Taylor, M.D.1
Zhang, X.2
Liu, L.3
Hui, C.-C.4
Mainprize, T.G.5
Scherer, S.W.6
Wainwright, B.7
Hogg, D.8
Rutka, J.T.9
-
14
-
-
0033583035
-
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3
-
Dai P, Akimaru H, Tanaka Y, Maekawa T, Nakafuku M and Ishii S: Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem 274: 8143-8152, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 8143-8152
-
-
Dai, P.1
Akimaru, H.2
Tanaka, Y.3
Maekawa, T.4
Nakafuku, M.5
Ishii, S.6
-
15
-
-
0344255675
-
β-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion
-
Usami N, Sekido Y, Maeda O, Yamamoto K, Minna JD, Hasegawa Y, Yoshioka H, Imaizumi M, Ueda Y, Takahashi M and Shimokata K: β-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion. Oncogene 22: 7923-7930, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 7923-7930
-
-
Usami, N.1
Sekido, Y.2
Maeda, O.3
Yamamoto, K.4
Minna, J.D.5
Hasegawa, Y.6
Yoshioka, H.7
Imaizumi, M.8
Ueda, Y.9
Takahashi, M.10
Shimokata, K.11
-
16
-
-
1342343924
-
Plakoglobin (gamma-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line
-
DOI 10.1038/sj.onc.1207254
-
Maeda O, Usami N, Kondo M, Takahashi M, Goto H, Shimokata K, Kusugami K and Sekido Y: Plakoglobin (γ-catenin) has TCF/LEF family-dependent transcriptional activity in β-catenin-deficient cell line. Oncogene 23: 964-972, 2004. (Pubitemid 38250942)
-
(2004)
Oncogene
, vol.23
, Issue.4
, pp. 964-972
-
-
Maeda, O.1
Usami, N.2
Kondo, M.3
Takahashi, M.4
Goto, H.5
Shimokata, K.6
Kusugami, K.7
Sekido, Y.8
-
17
-
-
0030891148
-
A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro
-
Sasaki H, Hui C, Nakafuku M and Kondoh H: A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 124: 1313-1322, 1997. (Pubitemid 27190104)
-
(1997)
Development
, vol.124
, Issue.7
, pp. 1313-1322
-
-
Sasaki, H.1
Hui, C.-C.2
Nakafuku, M.3
Kondoh, H.4
-
18
-
-
26444577884
-
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2
-
DOI 10.1093/hmg/ddi222
-
Roessler E, Ermilov AN, Grange DK, Wang A, Grachtchouk M, Dlugosz AA and Muenke M: A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. Hum Mol Genet 14: 2181-2188, 2005. (Pubitemid 41418017)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.15
, pp. 2181-2188
-
-
Roessler, E.1
Ermilov, A.N.2
Grange, D.K.3
Wang, A.4
Grachtchouk, M.5
Dlugosz, A.A.6
Muenke, M.7
-
19
-
-
0025743732
-
'Touchdown' PCR to circumvent spurious priming during gene amplification
-
Don RH, Cox PT, Wainwright BJ, Baker K and Mattick JS: 'Touchdown' PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res 19: 4008, 1991.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 4008
-
-
Don, R.H.1
Cox, P.T.2
Wainwright, B.J.3
Baker, K.4
Mattick, J.S.5
-
20
-
-
0036697802
-
Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor
-
Sekido Y, Sato M, Usami N, Shigemitsu K, Mori S, Maeda O, Yokoi T, Hasegawa Y, Yoshioka H and Shimokata K: Establishment of a large cell lung cancer cell line (Y-ML-1B) producing granulocyte colony-stimulating factor. Cancer Genet Cytogenet 137: 33-42, 2002.
-
(2002)
Cancer Genet Cytogenet
, vol.137
, pp. 33-42
-
-
Sekido, Y.1
Sato, M.2
Usami, N.3
Shigemitsu, K.4
Mori, S.5
Maeda, O.6
Yokoi, T.7
Hasegawa, Y.8
Yoshioka, H.9
Shimokata, K.10
-
21
-
-
17944377840
-
Genetic alteration of the β-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion
-
DOI 10.1038/sj.onc.1204557
-
Shigemitsu K, Sekido Y, Usami N, Mori S, Sato M, Horio Y, Hasegawa Y, Bader SA, Gazdar AF, Minna JD, Hida T, Yoshioka H, Imaizumi M, Ueda Y, Takahashi M and Shimokata K: Genetic alteration of the β-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion. Oncogene 20: 4249-4257, 2001. (Pubitemid 32762199)
-
(2001)
Oncogene
, vol.20
, Issue.31
, pp. 4249-4257
-
-
Shigemitsu, K.1
Sekido, Y.2
Usami, N.3
Mori, S.4
Sato, M.5
Horio, Y.6
Hasegawa, Y.7
Bader, S.A.8
Gazdar, A.F.9
Minna, J.D.10
Hida, T.11
Yoshioka, H.12
Imaizumi, M.13
Ueda, Y.14
Takahashi, M.15
Shimokata, K.16
-
22
-
-
0033754122
-
The sonic hedgehog-patched-gli pathway in human development and disease
-
Villavicencio EH, Walterhouse DO and Iannaccone PM: The sonic hedgehog-patched-gli pathway in human development and disease. Am J Hum Genet 67: 1047-1054, 2000.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 1047-1054
-
-
Villavicencio, E.H.1
Walterhouse, D.O.2
Iannaccone, P.M.3
-
23
-
-
0032808138
-
Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
-
Ruiz i Altaba A: Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126: 3205-3216, 1999.
-
(1999)
Development
, vol.126
, pp. 3205-3216
-
-
Ruiz I Altaba, A.1
-
24
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang B, Fallon JF and Beachy PA: Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434, 2000.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
25
-
-
0142153787
-
The hedgehog signaling network
-
Cohen MM Jr: The hedgehog signaling network. Am J Med Genet A 123: 5-28, 2003.
-
(2003)
Am J Med Genet A
, vol.123
, pp. 5-28
-
-
Cohen Jr., M.M.1
-
26
-
-
0030844141
-
Activation of the transcription factor Gli1 and the sonic hedgehog signalling pathway in skin tumours
-
DOI 10.1038/39918
-
Dahmane N, Lee J, Robins P, Heller P and Ruiz i Altaba A: Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 389: 876-881, 1997. (Pubitemid 27462984)
-
(1997)
Nature
, vol.389
, Issue.6653
, pp. 876-881
-
-
Dahmane, N.1
Lee, J.2
Robins, P.3
Heller, P.4
Ruiz I, A.A.5
-
27
-
-
0033561641
-
GLI gene expression in bone and soft tissue sarcomas of adult patients correlates with tumor grade
-
Stein U, Eder C, Karsten U, Haensch W, Walther W and Schlag PM: GLI gene expression in bone and soft tissue sarcomas of adult patients correlates with tumor grade. Cancer Res 59: 1890-1895, 1999. (Pubitemid 29186162)
-
(1999)
Cancer Research
, vol.59
, Issue.8
, pp. 1890-1895
-
-
Stein, U.1
Eder, C.2
Karsten, U.3
Haensch, W.4
Walther, W.5
Schlag, P.M.6
-
28
-
-
10744233571
-
Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation
-
DOI 10.1038/ng1304
-
Van den Brink GR, Bleuming SA, Hardwick JC, Schepman BL, Offerhaus GJ, Keller JJ, Nielsen C, Gaffield W, Van Deventer SJ, Roberts DJ and Peppelenbosch MP: Indian Hedgehog is an antagonist of Wnt signaling in colonic epithelial cell differentiation. Nat Genet 36: 277-282, 2004. (Pubitemid 38282753)
-
(2004)
Nature Genetics
, vol.36
, Issue.3
, pp. 277-282
-
-
Van Den, B.G.R.1
Bleuming, S.A.2
Hardwick, J.C.H.3
Schepman, B.L.4
Offerhaus, G.J.5
Keller, J.J.6
Nielsen, C.7
Gaffield, W.8
Van Deventer, S.J.H.9
Roberts, D.J.10
Peppelenbosch, M.P.11
|