Human homolog of patched, a candidate gene for the basal cell nevus syndrome

Science

Volumn 272, Issue 5268, 1996, Pages 1668-1671

  Johnson, Ronald L ^a   Rothman, Alana L ^b   Xie, Jingwu ^b   Goodrich, Lisa V ^a   Bare, John W ^b   Bonifas, Jeannette M ^b   Quinn, Anthony G ^b,c   Myers, Richard M ^a   Cox, David R ^a   Epstein Jr , Ervin H ^b   Scott, Matthew P ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN;

ADULT; ANIMAL TISSUE; ARTICLE; BASAL CELL CARCINOMA; BASAL CELL NEVUS SYNDROME; CANCER GENETICS; CANCER INHIBITION; CONTROLLED STUDY; DROSOPHILA; EMBRYO DEVELOPMENT; FEMALE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE;

EID: 15844381336     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.272.5268.1668     Document Type: Article

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70. We thank the patients and family members who contributed samples and the physicians who helped us obtain patient materials. We also thank J. Fletcher for help in the genesis of the project; R. Gorlin and J. B. Howell for encouragement; J. Hooper for insights and ideas; G. Barsh, S. Kim, D. Kingsley, and A. Oro for comments on the manuscript; X. Zhang for assistance; and M. Nguyen and A. Smith for sequencing. Supported by the Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation Fellowship (DRG 1218) and a Walter Berry Fellowship to R.L.J., NIH grant AR3995 to E.H.E., a Dermatology Foundation Fellowship to J.X., a Medical Research Council Traveling Fellowship to A.G.Q., and a Howard Hughes Medical Institute (HHMI) Predoctoral Fellowship to L.V.G. M.P.S. is an Investigator of the HHMI.