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Volumn 1, Issue 4, 2005, Pages 0480-0488

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Author keywords

[No Author keywords available]

Indexed keywords

GLI3 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; NERVE PROTEIN; SONIC HEDGEHOG PROTEIN; TG737RPW PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GLI2; TUMOR SUPPRESSOR PROTEIN;

EID: 40749144679     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0010053     Document Type: Article
Times cited : (743)

References (33)
  • 1
    • 0345255945 scopus 로고    scopus 로고
    • Intraflagellar transport
    • Scholey JM (2003) Intraflagellar transport. Annu Rev Cell Dev Biol 19: 423-443.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 423-443
    • Scholey, J.M.1
  • 2
    • 0034735526 scopus 로고    scopus 로고
    • Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene Tg737, are required for assembly of cilia and flagella
    • Pazour GJ, Dickert BL, Vucica Y, Seeley ES, Rosenbaum JL, et al. (2000) Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene Tg737, are required for assembly of cilia and flagella. J Cell Biol 151: 709-718.
    • (2000) J Cell Biol , vol.151 , pp. 709-718
    • Pazour, G.J.1    Dickert, B.L.2    Vucica, Y.3    Seeley, E.S.4    Rosenbaum, J.L.5
  • 3
    • 0034042763 scopus 로고    scopus 로고
    • The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination
    • Murcia NS, Richards WG, Yoder BK, Mucenski ML, Dunlap JR, et al. (2000) The Oak Ridge Polycystic Kidney (orpk) disease gene is required for left-right axis determination. Development 127: 2347-2355.
    • (2000) Development , vol.127 , pp. 2347-2355
    • Murcia, N.S.1    Richards, W.G.2    Yoder, B.K.3    Mucenski, M.L.4    Dunlap, J.R.5
  • 4
    • 0028322016 scopus 로고
    • Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice
    • Moyer JH, Lee-Tischler MJ, Kwon HY, Schrick JJ, Avner ED, et al. (1994) Candidate gene associated with a mutation causing recessive polycystic kidney disease in mice. Science 264: 1329-1333.
    • (1994) Science , vol.264 , pp. 1329-1333
    • Moyer, J.H.1    Lee-Tischler, M.J.2    Kwon, H.Y.3    Schrick, J.J.4    Avner, E.D.5
  • 7
    • 0037389087 scopus 로고    scopus 로고
    • Patterning systems - From one end of the limb to the other
    • Tickle C (2003) Patterning systems - From one end of the limb to the other. Dev Cell 4: 449-458.
    • (2003) Dev Cell , vol.4 , pp. 449-458
    • Tickle, C.1
  • 8
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • Ingham PW, McMahon AP (2001) Hedgehog signaling in animal development: Paradigms and principles. Genes Dev 15: 3059-3087.
    • (2001) Genes Dev , vol.15 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 9
    • 0034681266 scopus 로고    scopus 로고
    • Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
    • Wang B, Fallon JF, Beachy PA (2000) Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100: 423-434.
    • (2000) Cell , vol.100 , pp. 423-434
    • Wang, B.1    Fallon, J.F.2    Beachy, P.A.3
  • 10
    • 0031020221 scopus 로고    scopus 로고
    • Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development
    • Mo R, Freer AM, Zinyk DL, Crackower MA, Michaud J, et al. (1997) Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124: 113-123.
    • (1997) Development , vol.124 , pp. 113-123
    • Mo, R.1    Freer, A.M.2    Zinyk, D.L.3    Crackower, Ma.4    Michaud, J.5
  • 11
    • 0034055649 scopus 로고    scopus 로고
    • Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
    • Park HL, Bai C, Platt KA, Matise MP, Beeghly A, et al. (2000) Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 127: 1593-1605.
    • (2000) Development , vol.127 , pp. 1593-1605
    • Park, H.L.1    Bai, C.2    Platt, K.A.3    Matise, M.P.4    Beeghly, A.5
  • 12
    • 0029117749 scopus 로고
    • A duplicated zone of polarizing activity in polydactylous mouse mutants
    • Masuya H, Sagai T, Wakana S, Moriwaki K, Shiroishi T (1995) A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes Dev 9: 1645-1653.
    • (1995) Genes Dev , vol.9 , pp. 1645-1653
    • Masuya, H.1    Sagai, T.2    Wakana, S.3    Moriwaki, K.4    Shiroishi, T.5
  • 13
    • 0037194765 scopus 로고    scopus 로고
    • Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity
    • Litingtung Y, Dahn RD, Li Y, Fallon JF, Chiang C (2002) Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity. Nature 418: 979-983.
    • (2002) Nature , vol.418 , pp. 979-983
    • Litingtung, Y.1    Dahn, R.D.2    Li, Y.3    Fallon, J.F.4    Chiang, C.5
  • 14
    • 0037174679 scopus 로고    scopus 로고
    • Progression of vertebrate limb development through SHH-mediated counteraction of GLI3
    • te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, et al. (2002) Progression of vertebrate limb development through SHH-mediated counteraction of GLI3. Science 298: 827-830.
    • (2002) Science , vol.298 , pp. 827-830
    • Welscher, P.1    Zuniga, A.2    Kuijper, S.3    Drenth, T.4    Goedemans, H.J.5
  • 15
    • 0033491071 scopus 로고    scopus 로고
    • Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
    • Stone DM, Murone M, Luoh S, Ye W, Armanini MP, et al. (1999) Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. J Cell Sci 112: 4437-4448.
    • (1999) J Cell Sci , vol.112 , pp. 4437-4448
    • Stone, D.M.1    Murone, M.2    Luoh, S.3    Ye, W.4    Armanini, M.P.5
  • 16
    • 0033533714 scopus 로고    scopus 로고
    • Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
    • Ding Q, Fukami S, Meng X, Nishizaki Y, Zhang X, et al. (1999) Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 9: 1119-1122.
    • (1999) Curr Biol , vol.9 , pp. 1119-1122
    • Ding, Q.1    Fukami, S.2    Meng, X.3    Nishizaki, Y.4    Zhang, X.5
  • 17
    • 0038813753 scopus 로고    scopus 로고
    • Characterization of the physical interaction of Gli proteins with SUFU proteins
    • Dunaeva M, Michelson P, Kogerman P, Toftgard R (2003) Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem 278: 5116-5122.
    • (2003) J Biol Chem , vol.278 , pp. 5116-5122
    • Dunaeva, M.1    Michelson, P.2    Kogerman, P.3    Toftgard, R.4
  • 18
    • 0242581681 scopus 로고    scopus 로고
    • Hedgehog signalling in the mouse requires intraflagellar transport proteins
    • Huangfu D, Liu A, Rakeman AS, Murcia NS, Niswander L, et al. (2003) Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 426: 83-87.
    • (2003) Nature , vol.426 , pp. 83-87
    • Huangfu, D.1    Liu, A.2    Rakeman, A.S.3    Murcia, N.S.4    Niswander, L.5
  • 19
    • 23144466931 scopus 로고    scopus 로고
    • Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
    • Liu A, Wang B, Niswander LA (2005) Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132: 3103-3111.
    • (2005) Development , vol.132 , pp. 3103-3111
    • Liu, A.1    Wang, B.2    Niswander, L.A.3
  • 20
    • 23844485210 scopus 로고    scopus 로고
    • Cilia and Hedgehog responsiveness in the mouse
    • Huangfu D, Anderson KV (2005) Cilia and Hedgehog responsiveness in the mouse. Proc Natl Acad Sci U S A 102: 11325-11330.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 11325-11330
    • Huangfu, D.1    Anderson, K.V.2
  • 21
    • 0346888543 scopus 로고    scopus 로고
    • Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction
    • Buttitta L, Mo R, Hui CC, Fan CM (2003) Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development 130: 6233-6243.
    • (2003) Development , vol.130 , pp. 6233-6243
    • Buttitta, L.1    Mo, R.2    Hui, C.C.3    Fan, C.M.4
  • 22
    • 0032808138 scopus 로고    scopus 로고
    • Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
    • Ruiz i Altaba A (1999) Gli proteins encode context-dependent positive and negative functions: Implications for development and disease. Development 126: 3205-3216.
    • (1999) Development , vol.126 , pp. 3205-3216
    • Ruiz I Altaba, A.1
  • 23
    • 0027478216 scopus 로고
    • A mouse model of Greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene
    • Hui CC, Joyner AL (1993) A mouse model of Greig cephalopolysyndactyly syndrome: The extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nat Genet 3: 241-246.
    • (1993) Nat Genet , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 24
    • 12344273107 scopus 로고    scopus 로고
    • Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice
    • Zhang Q, Davenport JR, Croyle MJ, Haycraft CJ, Yoder BK (2005) Disruption of IFT results in both exocrine and endocrine abnormalities in the pancreas of Tg737(orpk) mutant mice. Lab Invest 85: 45-64.
    • (2005) Lab Invest , vol.85 , pp. 45-64
    • Zhang, Q.1    Davenport, J.R.2    Croyle, M.J.3    Haycraft, C.J.4    Yoder, B.K.5
  • 25
    • 0036134643 scopus 로고    scopus 로고
    • High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion
    • Maynard TM, Jain MD, Balmer CW, LaMantia AS (2002) High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion. Mamm Genome 13: 58-61.
    • (2002) Mamm Genome , vol.13 , pp. 58-61
    • Maynard, T.M.1    Jain, M.D.2    Balmer, C.W.3    Lamantia, A.S.4
  • 27
    • 0030027059 scopus 로고    scopus 로고
    • Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog
    • Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP (1996) Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by Hedgehog. Genes Dev 10: 301-312.
    • (1996) Genes Dev , vol.10 , pp. 301-312
    • Goodrich, L.V.1    Johnson, R.L.2    Milenkovic, L.3    McMahon, J.A.4    Scott, M.P.5
  • 28
    • 0028281306 scopus 로고
    • Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development
    • Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL (1994) Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol 162: 402-413.
    • (1994) Dev Biol , vol.162 , pp. 402-413
    • Hui, C.C.1    Slusarski, D.2    Platt, K.A.3    Holmgren, R.4    Joyner, A.L.5
  • 29
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S
    • McLeod MJ (1980) Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology 22: 299-301.
    • (1980) Teratology , vol.22 , pp. 299-301
    • McLeod, M.J.1
  • 30
    • 0035822098 scopus 로고    scopus 로고
    • A freely diffusible form of Sonic hedgehog mediates long-range signalling
    • Zeng X, Goetz JA, Suber LM, Scott WJ Jr, Schreiner CM, et al. (2001) A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature 411: 716-720.
    • (2001) Nature , vol.411 , pp. 716-720
    • Zeng, X.1    Goetz, J.A.2    Suber, L.M.3    Scott Jr., W.J.4    Schreiner, C.M.5
  • 31
    • 0037447892 scopus 로고    scopus 로고
    • The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord
    • Meyer NP, Roelink H (2003) The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. Dev Biol 257: 343-355.
    • (2003) Dev Biol , vol.257 , pp. 343-355
    • Meyer, N.P.1    Roelink, H.2
  • 32
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 33
    • 0035159015 scopus 로고    scopus 로고
    • Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia
    • Taulman PD, Haycraft CJ, Balkovetz DF, Yoder BK (2001) Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia. Mol Biol Cell 12: 589-599.
    • (2001) Mol Biol Cell , vol.12 , pp. 589-599
    • Taulman, P.D.1    Haycraft, C.J.2    Balkovetz, D.F.3    Yoder, B.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.