-
2
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri A, Yarden Y. EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol 2006; 7: 505-16.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
3
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, Normanno N. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995; 19: 183-232.
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
Normanno, N.4
-
4
-
-
0032478998
-
Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
-
Rubin Grandis J, Melhem MF, Gooding WE, Day R, Holst VA, Wagener MM. Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J Natl Cancer Inst 1998; 90: 824-32.
-
(1998)
J Natl Cancer Inst
, vol.90
, pp. 824-832
-
-
Rubin Grandis, J.1
Melhem, M.F.2
Gooding, W.E.3
Day, R.4
Holst, V.A.5
Wagener, M.M.6
-
5
-
-
33746485766
-
Epidermal growth factor receptor targeting in cancer
-
Mendelsohn J, Baselga J. Epidermal growth factor receptor targeting in cancer. Semin Oncol 2006; 33: 369-85.
-
(2006)
Semin Oncol
, vol.33
, pp. 369-385
-
-
Mendelsohn, J.1
Baselga, J.2
-
6
-
-
0034486406
-
On receptor inhibitors and chemotherapy
-
Ryan PD, Chabner BA. On receptor inhibitors and chemotherapy. Clin Cancer Res 2000; 6: 4607-9.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4607-4609
-
-
Ryan, P.D.1
Chabner, B.A.2
-
7
-
-
0027290650
-
Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies
-
Baselga J, Norton L, Masui H, et al. Antitumor effects of doxorubicin in combination with anti-epidermal growth factor receptor monoclonal antibodies. J Natl Cancer Inst 1993; 85: 1327-33.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1327-1333
-
-
Baselga, J.1
Norton, L.2
Masui, H.3
-
8
-
-
0028116305
-
Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells
-
Fan Z, Lu Y, Wu X, Mendelsohn J. Antibody-induced epidermal growth factor receptor dimerization mediates inhibition of autocrine proliferation of A431 squamous carcinoma cells. J Biol Chem 1994; 269: 27595-602.
-
(1994)
J Biol Chem
, vol.269
, pp. 27595-27602
-
-
Fan, Z.1
Lu, Y.2
Wu, X.3
Mendelsohn, J.4
-
9
-
-
0030324626
-
The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma
-
Prewett M, Rockwell P, Rockwell RF, et al. The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma. J Immunother Emphasis Tumor Immunol 1996; 19: 419-27.
-
(1996)
J Immunother Emphasis Tumor Immunol
, vol.19
, pp. 419-427
-
-
Prewett, M.1
Rockwell, P.2
Rockwell, R.F.3
-
10
-
-
0032904485
-
Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225
-
Ciardiello F, Bianco R, DamianoV, et al. Antitumor activity of sequential treatment with topotecan and anti-epidermal growth factor receptor monoclonal antibody C225. Clin Cancer Res 1999; 5: 909-16.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 909-916
-
-
Ciardiello, F.1
Bianco, R.2
DamianoV3
-
11
-
-
18844473781
-
Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms
-
Bruns CJ, Harbison MT, Davis DW, et al. Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms. Clin Cancer Res 2000; 6: 1936-48.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 1936-1948
-
-
Bruns, C.J.1
Harbison, M.T.2
Davis, D.W.3
-
12
-
-
0345098557
-
Monoclonal antibodies in human cancer
-
Mellstedt H. Monoclonal antibodies in human cancer. Drugs Today (Barc) 2003; 39: 1-16.
-
(2003)
Drugs Today (Barc)
, vol.39
, pp. 1-16
-
-
Mellstedt, H.1
-
13
-
-
33846564399
-
Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma
-
Kawaguchi Y, Kono K, Mimura K, Sugai H, Akaike H, Fujii H. Cetuximab induce antibody-dependent cellular cytotoxicity against EGFR-expressing esophageal squamous cell carcinoma. Int J Cancer 2007; 120: 781-7.
-
(2007)
Int J Cancer
, vol.120
, pp. 781-787
-
-
Kawaguchi, Y.1
Kono, K.2
Mimura, K.3
Sugai, H.4
Akaike, H.5
Fujii, H.6
-
14
-
-
28444453967
-
Inhibition of radiation-induced EGFR nuclear import by C225 (cetuximab) suppresses DNA-PK activity
-
Dittmann K, Mayer C, Rodemann HP. Inhibition of radiation-induced EGFR nuclear import by C225 (cetuximab) suppresses DNA-PK activity. Radiother Oncol 2005; 76: 157-61.
-
(2005)
Radiother Oncol
, vol.76
, pp. 157-161
-
-
Dittmann, K.1
Mayer, C.2
Rodemann, H.P.3
-
15
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
Huang SM, Bock JM, Harari PM. Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 1999; 59: 1935-40.
-
(1999)
Cancer Res
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
16
-
-
0034329308
-
Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers
-
Bonner JA, Raisch KP, Trummell HQ, et al. Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers. J Clin Oncol 2000; 18: 47S-53S.
-
(2000)
J Clin Oncol
, vol.18
-
-
Bonner, J.A.1
Raisch, K.P.2
Trummell, H.Q.3
-
17
-
-
17344382185
-
Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation
-
Saleh MN, Raisch KP, Stackhouse MA, et al. Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation. Cancer Biother Radiopharm 1999; 14: 451-63.
-
(1999)
Cancer Biother Radiopharm
, vol.14
, pp. 451-463
-
-
Saleh, M.N.1
Raisch, K.P.2
Stackhouse, M.A.3
-
18
-
-
0033966576
-
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
-
Milas L, Mason K, Hunter N, et al. In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res 2000; 6: 701-8.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 701-708
-
-
Milas, L.1
Mason, K.2
Hunter, N.3
-
19
-
-
0035479052
-
C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability
-
Nasu S, Ang KK, Fan Z, Milas L. C225 antiepidermal growth factor receptor antibody enhances tumor radiocurability. Int J Radiat Oncol Biol Phys 2001; 51: 474-7.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.51
, pp. 474-477
-
-
Nasu, S.1
Ang, K.K.2
Fan, Z.3
Milas, L.4
-
20
-
-
0037111274
-
Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation
-
Buchsbaum DJ, Bonner JA, Grizzle WE, et al. Treatment of pancreatic cancer xenografts with Erbitux (IMC-C225) anti-EGFR antibody, gemcitabine, and radiation. Int J Radiat Oncol Biol Phys 2002; 54: 1180-93.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1180-1193
-
-
Buchsbaum, D.J.1
Bonner, J.A.2
Grizzle, W.E.3
-
21
-
-
0027428571
-
Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts
-
Fan Z, Baselga J, Masui H, Mendelsohn J. Antitumor effect of anti-epidermal growth factor receptor monoclonal antibodies plus cis-diamminedichloroplatinum on well established A431 cell xenografts. Cancer Res 1993; 53: 4637-42.
-
(1993)
Cancer Res
, vol.53
, pp. 4637-4642
-
-
Fan, Z.1
Baselga, J.2
Masui, H.3
Mendelsohn, J.4
-
22
-
-
0036096775
-
Inhibition of angiogenesis by the anti epidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice
-
Karashima T, Sweeney P, Slaton JW, et al. Inhibition of angiogenesis by the anti epidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice. Clin Cancer Res 2002; 8: 1253-64.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1253-1264
-
-
Karashima, T.1
Sweeney, P.2
Slaton, J.W.3
-
23
-
-
0036094194
-
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts
-
Prewett MC, Hooper AT, Bassi R, Ellis LM, Waksal HW, Hicklin DJ. Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts. Clin Cancer Res 2002; 8: 994-1003.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 994-1003
-
-
Prewett, M.C.1
Hooper, A.T.2
Bassi, R.3
Ellis, L.M.4
Waksal, H.W.5
Hicklin, D.J.6
-
24
-
-
13844288284
-
Dose-dependent inhibition of the EGFR and signalling pathways with the anti-EGFR monoclonal antibody (Mab) EMD 72000 administered every three weeks (q3w). A phase I pharmacokinetic/pharmcodynamic (PK/PD) study to define the optimal biological dose (OBD)
-
Abstract
-
Salazar R, Tabernero J, Rojo F, et al. Dose-dependent inhibition of the EGFR and signalling pathways with the anti-EGFR monoclonal antibody (Mab) EMD 72000 administered every three weeks (q3w). A phase I pharmacokinetic/pharmcodynamic (PK/PD) study to define the optimal biological dose (OBD). Proc Am Soc Clin Oncol 2004; Abstract 2002.
-
(2002)
Proc Am Soc Clin Oncol
-
-
Salazar, R.1
Tabernero, J.2
Rojo, F.3
-
25
-
-
0035117355
-
Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody for cancer therapy
-
Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG. Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody for cancer therapy. Crit Rev Oncol Hematol 2001; 38: 17-23.
-
(2001)
Crit Rev Oncol Hematol
, vol.38
, pp. 17-23
-
-
Yang, X.D.1
Jia, X.C.2
Corvalan, J.R.3
Wang, P.4
Davis, C.G.5
-
26
-
-
0033559606
-
Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy
-
Yang XD, Jia XC, Corvalan JR, Wang P, Davis CG, Jakobovits A. Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy. Cancer Res 1999; 59: 1236-43.
-
(1999)
Cancer Res
, vol.59
, pp. 1236-1243
-
-
Yang, X.D.1
Jia, X.C.2
Corvalan, J.R.3
Wang, P.4
Davis, C.G.5
Jakobovits, A.6
-
27
-
-
0037374686
-
Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD 1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells
-
Di Gennaro E, Barbarino M, Bruzzese F, et al. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD 1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells. J Cell Physiol 2003; 1: 139-50.
-
(2003)
J Cell Physiol
, vol.1
, pp. 139-150
-
-
Di Gennaro, E.1
Barbarino, M.2
Bruzzese, F.3
-
28
-
-
0035423120
-
Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors
-
Lichtner RB, Menrad A, Sommer A, Klar U, Schneider MR. Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors. Cancer Res 2001; 61: 5790-5.
-
(2001)
Cancer Res
, vol.61
, pp. 5790-5795
-
-
Lichtner, R.B.1
Menrad, A.2
Sommer, A.3
Klar, U.4
Schneider, M.R.5
-
29
-
-
0034068319
-
Antitumor effect and potentiation of cytotoxic drug activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor selective tyrosine kinase inhibitor
-
Ciardiello F, Caputo R, Bianco R, et al. Antitumor effect and potentiation of cytotoxic drug activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor selective tyrosine kinase inhibitor. Clin Cancer Res 2000; 6: 2053-63.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2053-2063
-
-
Ciardiello, F.1
Caputo, R.2
Bianco, R.3
|