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Volumn 426, Issue 6962, 2003, Pages 83-87

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Author keywords

[No Author keywords available]

Indexed keywords

ALGAE; BIOCHEMISTRY; GROWTH KINETICS; MUTAGENESIS; PROTEINS; TRANSPORT PROPERTIES;

EID: 0242581681     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02061     Document Type: Article
Times cited : (1145)

References (30)
  • 2
    • 0037020216 scopus 로고    scopus 로고
    • Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of Dispatched
    • Ma, Y. et al. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of Dispatched. Cell, 111, 63-75 (2002).
    • (2002) Cell , vol.111 , pp. 63-75
    • Ma, Y.1
  • 3
    • 0037125938 scopus 로고    scopus 로고
    • Mouse Dispatched homologl is required for long-range, but not juxtacrine, Hh signaling
    • Caspary, T. et al. Mouse Dispatched homologl is required for long-range, but not juxtacrine, Hh signaling. Curr. Biol. 12, 1628-1632 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 1628-1632
    • Caspary, T.1
  • 4
    • 0034042763 scopus 로고    scopus 로고
    • The Oak Ridge polycystic kidney (orpk) disease gene is required for left right axis determination
    • Murcia, N. S. et al. The Oak Ridge polycystic kidney (orpk) disease gene is required for left right axis determination. Development 127, 2347-2355 (2000).
    • (2000) Development , vol.127 , pp. 2347-2355
    • Murcia, N.S.1
  • 5
    • 0029993646 scopus 로고    scopus 로고
    • Relationship between asymmetric nodal expression and the direction of embryonic turning
    • Collignon, J., Varlet, I. & Robertson, E. J. Relationship between asymmetric nodal expression and the direction of embryonic turning. Nature 381, 155-158 (1996).
    • (1996) Nature , vol.381 , pp. 155-158
    • Collignon, J.1    Varlet, I.2    Robertson, E.J.3
  • 6
    • 0033865564 scopus 로고    scopus 로고
    • Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells
    • Schimenti, J. C. et al. Interdigitated deletion complexes on mouse chromosome 5 induced by irradiation of embryonic stem cells. Genome Res. 10, 1043-1050 (2000).
    • (2000) Genome Res. , vol.10 , pp. 1043-1050
    • Schimenti, J.C.1
  • 7
    • 0037706929 scopus 로고    scopus 로고
    • Differential requirement for Gli 2 and Gli3 in ventral neural cell fate specification
    • Motoyama, J. et al. Differential requirement for Gli2 and Gli3 in ventral neural cell fate specification. Dev. Biol. 259, 150-161 (2003).
    • (2003) Dev. Biol. , vol.259 , pp. 150-161
    • Motoyama, J.1
  • 8
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
    • Chiang, C. et al. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413 (1996).
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1
  • 9
    • 0033779316 scopus 로고    scopus 로고
    • Control of Shh activity and signaling in the neural tube
    • Litingtung, Y. & Chiang, C. Control of Shh activity and signaling in the neural tube. Dev. Dyn. 219, 143-154 (2000).
    • (2000) Dev. Dyn. , vol.219 , pp. 143-154
    • Litingtung, Y.1    Chiang, C.2
  • 10
    • 0033577894 scopus 로고    scopus 로고
    • -/- mice analysis
    • -/- mice analysis. J. Cell Biol. 145, 825-836 (1999).
    • (1999) J. Cell Biol. , vol.145 , pp. 825-836
    • Takeda, S.1
  • 11
    • 0033609103 scopus 로고    scopus 로고
    • Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II
    • Marszalek, J. R., Ruiz-Lozano, P., Roberts, E., Chien, K. R. & Goldstein, L. S. Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II. Proc. Natl Acad. Sci. USA 96, 5043-5048 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 5043-5048
    • Marszalek, J.R.1    Ruiz-Lozano, P.2    Roberts, E.3    Chien, K.R.4    Goldstein, L.S.5
  • 12
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • Goodrich, L. V., Milenkovic, L., Higgins, K. M. & Scott, M. P. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277, 1109-1113 (1997).
    • (1997) Science , vol.277 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3    Scott, M.P.4
  • 13
    • 0035849901 scopus 로고    scopus 로고
    • Rab 23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway
    • Eggenschwiler, J. T., Espinoza, E. & Anderson, K. V. Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature 412, 194-198 (2001).
    • (2001) Nature , vol.412 , pp. 194-198
    • Eggenschwiler, J.T.1    Espinoza, E.2    Anderson, K.V.3
  • 14
    • 0034669084 scopus 로고    scopus 로고
    • Dorsal and lateral fates in the mouse neural tube require the cell-autonomous activity of the open brain gene
    • Eggenschwiler, J. T. & Anderson, K. V. Dorsal and lateral fates in the mouse neural tube require the cell-autonomous activity of the open brain gene. Dev. Biol. 227, 648-660 (2000).
    • (2000) Dev. Biol. , vol.227 , pp. 648-660
    • Eggenschwiler, J.T.1    Anderson, K.V.2
  • 15
    • 0034681266 scopus 로고    scopus 로고
    • Hedgehog-regulated processing of Gli3 produces an anterior/ posterior repressor gradient in the developing vertebrate limb
    • Wang, B., Fallon, J. F. & Beachy, P. A. Hedgehog-regulated processing of Gli3 produces an anterior/ posterior repressor gradient in the developing vertebrate limb. Cell 100, 423-434 (2000).
    • (2000) Cell , vol.100 , pp. 423-434
    • Wang, B.1    Fallon, J.F.2    Beachy, P.A.3
  • 16
    • 0033808256 scopus 로고    scopus 로고
    • Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli 3
    • Litingtung, Y. & Chiang, C. Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3. Nature Neurosci. 3, 979-985 (2000).
    • (2000) Nature Neurosci. , vol.3 , pp. 979-985
    • Litingtung, Y.1    Chiang, C.2
  • 17
  • 18
    • 0030754171 scopus 로고    scopus 로고
    • Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway
    • Sisson, J. C., Ho, K. S., Suyama, K. & Scott, M. P. Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway. Cell 90, 235-245 (1997).
    • (1997) Cell , vol.90 , pp. 235-245
    • Sisson, J.C.1    Ho, K.S.2    Suyama, K.3    Scott, M.P.4
  • 19
    • 0033230363 scopus 로고    scopus 로고
    • Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila
    • Ray, K. et al. Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. J. Cell Biol. 147, 507-518 (1999).
    • (1999) J. Cell Biol. , vol.147 , pp. 507-518
    • Ray, K.1
  • 20
    • 0141480791 scopus 로고    scopus 로고
    • Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm
    • Han, Y., Kwok, B. H. & Kernan, M. J. Intraflagellar transport is required in Drosophila to differentiate sensory cilia but not sperm. Curr. Biol. 13, 1679-1686 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 1679-1686
    • Han, Y.1    Kwok, B.H.2    Kernan, M.J.3
  • 21
    • 0036406843 scopus 로고    scopus 로고
    • Hedgehog signaling and human disease
    • Bale, A. E. Hedgehog signaling and human disease. Annu. Rev. Genom. Hum. Genet. 3, 47-65 (2002).
    • (2002) Annu. Rev. Genom. Hum. Genet. , vol.3 , pp. 47-65
    • Bale, A.E.1
  • 22
    • 0036250552 scopus 로고    scopus 로고
    • A healthy understanding of intraflagellar transport
    • Sloboda, R. D. A healthy understanding of intraflagellar transport. Cell Motil. Cytoskeleton 52, 1-8 (2002).
    • (2002) Cell Motil. Cytoskeleton , vol.52 , pp. 1-8
    • Sloboda, R.D.1
  • 23
    • 0032560518 scopus 로고    scopus 로고
    • A phenotype-based screen for embryonic lethal mutations in the mouse
    • Kasarskis, A., Manova, K. & Anderson, K. V. A phenotype-based screen for embryonic lethal mutations in the mouse. Proc. Natl Acad. Sci. USA 95, 7485-7490 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 7485-7490
    • Kasarskis, A.1    Manova, K.2    Anderson, K.V.3
  • 24
    • 0027478216 scopus 로고
    • A mouse model of Greig cephalopolysyndactyly syndrome: The extra-toes mutation contains an intragenic deletion of the Gli 3 gene
    • Hui, C. C. & Joyner, A. L. A mouse model of Greig cephalopolysyndactyly syndrome: the extra-toes mutation contains an intragenic deletion of the Gli3 gene. Nature Genet. 3, 241-246 (1993).
    • (1993) Nature Genet. , vol.3 , pp. 241-246
    • Hui, C.C.1    Joyner, A.L.2
  • 25
    • 0033574071 scopus 로고    scopus 로고
    • Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT 3 gene
    • Cole, T. B., Wenzel, H. J., Kafer, K. E., Schwartzkroin, P. A. & Palmiter, R. D. Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene. Proc. Nalt Acad. Sci. USA 96, 1716-1721 (1999).
    • (1999) Proc. Nalt Acad. Sci. USA , vol.96 , pp. 1716-1721
    • Cole, T.B.1    Wenzel, H.J.2    Kafer, K.E.3    Schwartzkroin, P.A.4    Palmiter, R.D.5
  • 26
    • 0036699527 scopus 로고    scopus 로고
    • Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior
    • Vetter, D. E. et al. Urocortin-deficient mice show hearing impairment and increased anxiety-like behavior. Nature Genet. 31, 363-369 (2002).
    • (2002) Nature Genet. , vol.31 , pp. 363-369
    • Vetter, D.E.1
  • 27
    • 0025091459 scopus 로고
    • Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome
    • Weiher, H., Noda, T., Gray, D. A., Sharpe, A. H. & Jaenisch, R. Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome. Cell 62, 425-434 (1990).
    • (1990) Cell , vol.62 , pp. 425-434
    • Weiher, H.1    Noda, T.2    Gray, D.A.3    Sharpe, A.H.4    Jaenisch, R.5
  • 28
    • 0033432692 scopus 로고    scopus 로고
    • Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: A sequestration mechanism in metabolic regulation
    • Farrelly, D et al. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation. Proc Natl Acad. Sci. USA 96, 14511-14516 (1999).
    • (1999) Proc Natl Acad. Sci. USA , vol.96 , pp. 14511-14516
    • Farrelly, D.1
  • 29
    • 0034607996 scopus 로고    scopus 로고
    • Identification ofa conserved protein that interacts with specific LIM homeodomain transcription factors
    • Howard, P. W. & Maurer, R. A. Identification ofa conserved protein that interacts with specific LIM homeodomain transcription factors. J. Biol. Chem. 275, 13336-13342 (2000).
    • (2000) J. Biol. Chem. , vol.275 , pp. 13336-13342
    • Howard, P.W.1    Maurer, R.A.2
  • 30
    • 0027985756 scopus 로고
    • Morphogenesis of the murine node and notochordal plate
    • Sulik, K. et al. Morphogenesis of the murine node and notochordal plate. Dev. Dyn. 201, 260-278 (1994).
    • (1994) Dev. Dyn. , vol.201 , pp. 260-278
    • Sulik, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.