Osteogenic oxysterol, 20( S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells

Journal of Bone and Mineral Research

Volumn 25, Issue 4, 2010, Pages 782-795

  Kim, Woo Kyun ^a   Meliton, Vicente ^a   Tetradis, Sotirios ^b   Weinmaster, Gerry ^a   Hahn, Theodore J ^c   Carlson, Marc ^a   Nelson, Stanley F ^a   Parhami, Farhad ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCLA SCHOOL OF DENTISTRY   (United States)

^c VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

Author keywords

Hedgehog; Mesenchymal stem cells; Notch; Osteogenesis; Oxysterol

Indexed keywords

20 HYDROXYCHOLESTEROL; CHOLESTEROL DERIVATIVE; CYCLOPAMINE; LIVER X RECEPTOR; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; NOTCH RECEPTOR; OXYSTEROL; SMALL INTERFERING RNA; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HEY 1; TRANSCRIPTION FACTOR HEY 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC TRANSFECTION; MOUSE; NONHUMAN; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; STROMA CELL;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE MARROW CELLS; CELL CULTURE TECHNIQUES; CELL CYCLE PROTEINS; FIBROBLASTS; GENE EXPRESSION; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; HYDROXYCHOLESTEROLS; MICE; ORPHAN NUCLEAR RECEPTORS; OSTEOGENESIS; RECEPTORS, NOTCH; RNA, MESSENGER; STROMAL CELLS; VERATRUM ALKALOIDS;

EID: 77953372061     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.091024     Document Type: Article

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