-
1
-
-
0035856920
-
Global and societal implications of the diabetes epidemic
-
Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature 2001;414:782-7.
-
(2001)
Nature
, vol.414
, pp. 782-787
-
-
Zimmet, P.1
Alberti, K.G.2
Shaw, J.3
-
2
-
-
0023924773
-
Impaired glucose tolerance as a disorder of insulin action: Longitudinal and cross-sectional studies in Pima Indians
-
Lillioja S, Mott DM, Howard BV, et al. Impaired glucose tolerance as a disorder of insulin action: longitudinal and cross-sectional studies in Pima Indians. N Engl J Med 1988;318:1217-25.
-
(1988)
N Engl J Med
, vol.318
, pp. 1217-1225
-
-
Lillioja, S.1
Mott, D.M.2
Howard, B.V.3
-
3
-
-
0027762766
-
Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus: Prospective studies of Pima Indians
-
Lillioja S, Mott DM, Spraul M, et al. Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus: prospective studies of Pima Indians. N Engl J Med 1993;329:1988-92.
-
(1993)
N Engl J Med
, vol.329
, pp. 1988-1992
-
-
Lillioja, S.1
Mott, D.M.2
Spraul, M.3
-
5
-
-
0025663581
-
Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic patients
-
Warram JH, Martin BC, Krolewski AS, Soeldner JS, Kahn CR. Slow glucose removal rate and hyperinsulinemia precede the development of type II diabetes in the offspring of diabetic patients. Ann Intern Med 1990; 113:909-15.
-
(1990)
Ann Intern Med
, vol.113
, pp. 909-915
-
-
Warram, J.H.1
Martin, B.C.2
Krolewski, A.S.3
Soeldner, J.S.4
Kahn, C.R.5
-
6
-
-
0029787329
-
Intramuscular triglyceride and muscle insulin sensitivity: Evidence for a relationship in nondiabetic subjects
-
Phillips DI, Caddy S, Ilic V, et al. Intramuscular triglyceride and muscle insulin sensitivity: evidence for a relationship in nondiabetic subjects. Metabolism 1996;45:947-50.
-
(1996)
Metabolism
, vol.45
, pp. 947-950
-
-
Phillips, D.I.1
Caddy, S.2
Ilic, V.3
-
7
-
-
0032934826
-
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: A 1H NMR spectroscopy study
-
Krssak M, Falk Petersen K, Dresner A, et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999;42:113-6. [Errata, Diabetologia 1999; 42:386, 1269.]
-
(1999)
Diabetologia
, vol.42
, pp. 113-116
-
-
Krssak, M.1
Falk Petersen, K.2
Dresner, A.3
-
8
-
-
0033032777
-
Errata
-
Krssak M, Falk Petersen K, Dresner A, et al. Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia 1999;42:113-6. [Errata, Diabetologia 1999; 42:386, 1269.]
-
(1999)
Diabetologia
, vol.42
, pp. 386
-
-
-
9
-
-
0032764784
-
Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: A 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents
-
Perseghin G, Scifo P, De Cobelli F, et al. Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents. Diabetes 1999;48:1600-6.
-
(1999)
Diabetes
, vol.48
, pp. 1600-1606
-
-
Perseghin, G.1
Scifo, P.2
De Cobelli, F.3
-
10
-
-
0033007207
-
Measurement of intracellular triglyceride stores by H spectroscopy: Validation in vivo
-
Szczepaniak LS, Babcock EE, Schick F, et al. Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol 1999;276:E977-E989.
-
(1999)
Am J Physiol
, vol.276
-
-
Szczepaniak, L.S.1
Babcock, E.E.2
Schick, F.3
-
11
-
-
0030941820
-
Metabolic defects in lean nondiabetic offspring of NIDDM parents: A cross-sectional study
-
Perseghin G, Ghosh S, Gerow K, Shulman GI. Metabolic defects in lean nondiabetic offspring of NIDDM parents: a cross-sectional study. Diabetes 1997;46:1001-9.
-
(1997)
Diabetes
, vol.46
, pp. 1001-1009
-
-
Perseghin, G.1
Ghosh, S.2
Gerow, K.3
Shulman, G.I.4
-
12
-
-
0345086474
-
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade
-
Griffin ME, Marcucci MJ, Cline GW, et al. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 1999;48:1270-4.
-
(1999)
Diabetes
, vol.48
, pp. 1270-1274
-
-
Griffin, M.E.1
Marcucci, M.J.2
Cline, G.W.3
-
13
-
-
0032954778
-
Effect of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
-
Dresner A, Laurent D, Marcucci M, et al. Effect of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest 1999;103:253-9.
-
(1999)
J Clin Invest
, vol.103
, pp. 253-259
-
-
Dresner, A.1
Laurent, D.2
Marcucci, M.3
-
14
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
Yu C, Chen Y, Cline GW, et al. Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J Biol Chem 2002;277: 50230-6.
-
(2002)
J Biol Chem
, vol.277
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
-
15
-
-
0036300538
-
Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha
-
Itani SI, Ruderman NB, Schmieder F, Boden G. Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes 2002;51:2005-11.
-
(2002)
Diabetes
, vol.51
, pp. 2005-2011
-
-
Itani, S.I.1
Ruderman, N.B.2
Schmieder, F.3
Boden, G.4
-
16
-
-
0028342686
-
Mechanisms of fatty acid-induced inhibition of glucose uptake
-
Boden G, Chen X, Kuiz J, White JV, Rossetti L. Mechanisms of fatty acid-induced inhibition of glucose uptake. J Clin Invest 1994;93:2438-46.
-
(1994)
J Clin Invest
, vol.93
, pp. 2438-2446
-
-
Boden, G.1
Chen, X.2
Kuiz, J.3
White, J.V.4
Rossetti, L.5
-
17
-
-
0029948212
-
Mechanism of free fatty acid-induced insulin resistance in humans
-
Roden M, Price TB, Perseghin G, et al. Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest 1996; 97:2859-65.
-
(1996)
J Clin Invest
, vol.97
, pp. 2859-2865
-
-
Roden, M.1
Price, T.B.2
Perseghin, G.3
-
18
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
19
-
-
0035023128
-
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
-
Kern PA, Ranganathan S, Li C, Wood L, Ranganathan G. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001;280:E745-E751.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Kern, P.A.1
Ranganathan, S.2
Li, C.3
Wood, L.4
Ranganathan, G.5
-
20
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature 2001;409:307-12.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
-
21
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauehi T, Kamon J, Waki H, et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001;7:941-6.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauehi, T.1
Kamon, J.2
Waki, H.3
-
22
-
-
0020417197
-
A short questionnaire for the measurement of habitual physical activity in epidemiological studies
-
Baecke JA, Burema J, Frijters JE. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 1982;36:936-42.
-
(1982)
Am J Clin Nutr
, vol.36
, pp. 936-942
-
-
Baecke, J.A.1
Burema, J.2
Frijters, J.E.3
-
23
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing: Comparison with the euglycemic insulin clamp
-
Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22: 1462-70.
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1470
-
-
Matsuda, M.1
DeFronzo, R.A.2
-
24
-
-
0027288808
-
Glucose metabolism during the menstrual cycle: Assessment with the euglycemic, hyperinsulinemic clamp
-
Diamond MP, Jacob K, Connolly-Diamond M, DeFronzo RA. Glucose metabolism during the menstrual cycle: assessment with the euglycemic, hyperinsulinemic clamp. J Reprod Med 1993;38:417-21.
-
(1993)
J Reprod Med
, vol.38
, pp. 417-421
-
-
Diamond, M.P.1
Jacob, K.2
Connolly-Diamond, M.3
DeFronzo, R.A.4
-
25
-
-
0020666381
-
A microfluorometric method for the determination of free fatty acids in plasma
-
Miles J, Glasscock R, Aikens J, Gerieh J, Raymond M. A microfluorometric method for the determination of free fatty acids in plasma. J Lipid Res 1983;24:96-9.
-
(1983)
J Lipid Res
, vol.24
, pp. 96-99
-
-
Miles, J.1
Glasscock, R.2
Aikens, J.3
Gerieh, J.4
Raymond, M.5
-
26
-
-
0036310037
-
The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
-
Mayerson AB, Hundal RS, Dufour S, et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 2002;51:797-802.
-
(2002)
Diabetes
, vol.51
, pp. 797-802
-
-
Mayerson, A.B.1
Hundal, R.S.2
Dufour, S.3
-
27
-
-
0032005178
-
Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: A randomized, double-blind, placebo-controlled trial
-
Maggs DG, Buchanan TA, Burant CF, et al. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998;128:176-85.
-
(1998)
Ann Intern Med
, vol.128
, pp. 176-185
-
-
Maggs, D.G.1
Buchanan, T.A.2
Burant, C.F.3
-
28
-
-
0031594368
-
13C/31P NMR studies on the mechanism of insulin resistance in obesity
-
Petersen KF, Hendler R, Price T, et al. 13C/31P NMR studies on the mechanism of insulin resistance in obesity. Diabetes 1998; 47:381-6.
-
(1998)
Diabetes
, vol.47
, pp. 381-386
-
-
Petersen, K.F.1
Hendler, R.2
Price, T.3
-
29
-
-
0034799676
-
Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle
-
Lebon V, Dufour S, Petersen KF, et al. Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle. J Clin Invest 2001;108:733-7.
-
(2001)
J Clin Invest
, vol.108
, pp. 733-737
-
-
Lebon, V.1
Dufour, S.2
Petersen, K.F.3
-
30
-
-
0022031580
-
Phosphorus nuclear magnetic resonance of fast- and slow-twitch muscle
-
Meyer RA, Brown TR, Kushmerick MJ. Phosphorus nuclear magnetic resonance of fast- and slow-twitch muscle. Am J Physiol 1985;248:C279-C287.
-
(1985)
Am J Physiol
, vol.248
-
-
Meyer, R.A.1
Brown, T.R.2
Kushmerick, M.J.3
-
31
-
-
0028968189
-
Energy-rich phosphates in slow and fast human skeletal muscle
-
Vandenborne K, Walter G, Ploutz-Snyder L, et al. Energy-rich phosphates in slow and fast human skeletal muscle. Am J Physiol 1995;268:C869-C876.
-
(1995)
Am J Physiol
, vol.268
-
-
Vandenborne, K.1
Walter, G.2
Ploutz-Snyder, L.3
-
32
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats
-
Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ, Storlien LH. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 1991;40:1397-403.
-
(1991)
Diabetes
, vol.40
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
Daley, E.A.4
Chisholm, D.J.5
Storlien, L.H.6
-
33
-
-
0035912744
-
Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance
-
Kim JK, Fillmore JJ, Chen Y, et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc Natl Acad Sci U S A 2001;98:7522-7.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 7522-7527
-
-
Kim, J.K.1
Fillmore, J.J.2
Chen, Y.3
-
34
-
-
0030669471
-
Evidence of an increased number of type IIb muscle fibers in insulin-resistant first-degree relatives of patients with NIDDM
-
Nyholm B, Qu Z, Kaal A, et al. Evidence of an increased number of type IIb muscle fibers in insulin-resistant first-degree relatives of patients with NIDDM. Diabetes 1997;46: 1822-8.
-
(1997)
Diabetes
, vol.46
, pp. 1822-1828
-
-
Nyholm, B.1
Qu, Z.2
Kaal, A.3
-
35
-
-
0036134187
-
Resistin and obesity-associated insulin resistance
-
Steppan CM, Lazar MA. Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 2002;13:18-23.
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 18-23
-
-
Steppan, C.M.1
Lazar, M.A.2
-
36
-
-
0037066603
-
ACRP30, a new hormone controlling fat and glucose metabolism
-
Tsao TS, Lodish HF, Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Eur J Pharmacol 2002;440:213-21.
-
(2002)
Eur J Pharmacol
, vol.440
, pp. 213-221
-
-
Tsao, T.S.1
Lodish, H.F.2
Fruebis, J.3
-
37
-
-
0041519355
-
Adiponectin: Systemic contributor to insulin sensitivity
-
Pajvani UB, Scherer PE. Adiponectin: systemic contributor to insulin sensitivity. Curr Diab Rep 2003;3:207-13.
-
(2003)
Curr Diab Rep
, vol.3
, pp. 207-213
-
-
Pajvani, U.B.1
Scherer, P.E.2
-
38
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002;8: 1288-95.
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
-
39
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen KF, Befroy D, Dufour S, et al. Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 2003; 300:1140-2.
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
-
40
-
-
0027924013
-
Mitokondriernas patofysiologi: Från Lufts sjukdom till åldrande och diabetes
-
Luft R, Luthman H. Mitokondriernas patofysiologi: från Lufts sjukdom till åldrande och diabetes. Lakartidningen 1993;90:2770-5.
-
(1993)
Lakartidningen
, vol.90
, pp. 2770-2775
-
-
Luft, R.1
Luthman, H.2
-
41
-
-
0033538473
-
Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1
-
Wu Z, Puigserver P, Andersson U, et al. Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1. Cell 1999;98: 115-24.
-
(1999)
Cell
, vol.98
, pp. 115-124
-
-
Wu, Z.1
Puigserver, P.2
Andersson, U.3
-
42
-
-
0035676129
-
Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus
-
Ek J, Andersen G, Urhammer SA, et al. Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus. Diabetologia 2001;44:2220-6.
-
(2001)
Diabetologia
, vol.44
, pp. 2220-2226
-
-
Ek, J.1
Andersen, G.2
Urhammer, S.A.3
-
43
-
-
0037340930
-
A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians
-
Muller YL, Bogardus C, Pedersen O, Baier L. A Gly482Ser missense mutation in the peroxisome proliferator-activated receptor gamma coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians. Diabetes 2003;52:895-8.
-
(2003)
Diabetes
, vol.52
, pp. 895-898
-
-
Muller, Y.L.1
Bogardus, C.2
Pedersen, O.3
Baier, L.4
-
44
-
-
0038054341
-
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
-
Mootha VK, Lindgren CM, Eriksson KF, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003;34:267-73.
-
(2003)
Nat Genet
, vol.34
, pp. 267-273
-
-
Mootha, V.K.1
Lindgren, C.M.2
Eriksson, K.F.3
-
45
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
Patti ME, Butte AJ, Crunkhorn S, et al. Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A 2003; 100:8466-71.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
|