The interaction between FOXO and SIRT1: Tipping the balance towards survival

Trends in Cell Biology

Volumn 14, Issue 8, 2004, Pages 408-412

  Giannakou, Maria E ^a   Partridge, Linda ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE; SILENT INFORMATION REGULATOR PROTEIN 2; SIRT1 PROTEIN; SIRTUIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXO; UNCLASSIFIED DRUG;

ACETYLATION; APOPTOSIS; CELL CYCLE; CELL METABOLISM; CELL SURVIVAL; DEACETYLATION; DNA REPAIR; GENE INTERACTION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; KNOCKOUT MOUSE; LIFESPAN; LONGEVITY; MAMMAL CELL; MOLECULAR INTERACTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REVIEW; SEQUENCE HOMOLOGY;

CAENORHABDITIS; CAENORHABDITIS ELEGANS; MAMMALIA; NEMATODA; SACCHAROMYCETALES;

EID: 4143050290     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2004.07.006     Document Type: Short Survey

References (26)

1. A. Dillin Timing requirements for insulin/IGF-1 signaling in C. elegans Science 298 2002 830 834
2. D.J. Clancy Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein Science 292 2001 104 106
3. H. Liang Genetic mouse models of extended lifespan Exp. Gerontol. 38 2003 1353 1364
4. S. Imai Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase Nature 403 2000 795 800
5. L. Guarente Sir2 links chromatin silencing, metabolism and aging Genes Dev. 14 2000 1021 1026
6. M. Kaeberlain The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms Genes Dev. 13 1999 2570 2580
7. H.A. Tissenbaum, and L. Guarente Nature 410 2001 227 230
8. S. Ogg The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans Nature 389 1997 994 999
9. K. Lin daf-16: an HNF-3/forkhead family member that can function to double the lifespan of Caenorhabditis elegans Science 278 1997 1319 1322
10. C. Kenyon A C. elegans mutant that lives twice as long as wild type Nature 366 1993 461 464
11. M.C. Motta Mammalian SIRT1 represses forkhead transcription factors Cell 116 2004 551 563
12. A. Brunet Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase Science 303 2004 2011 2015
13. SIRT1. J. Biol. Chem. 10.1074/jbc.M401138200 (www.jbc.org)
14. R.A. Frye Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins Biochem. Biophys. Res. Commun. 273 2000 793 798
15. J. Luo Negative control of p53 by Sir2a promotes cell survival under stress Cell 107 2001 137 148
16. N. Nasrin DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells Proc. Natl. Acad. Sci. U. S. A. 97 2000 10412 10417
17. M. Fukuoka Negative regulation of forkhead transcription factor AFX (FOXO4) by CBP-induced acetylation Int. J. Mol. Med. 12 2003 503 508
18. Y. Honda, and S. Honda The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans FASEB J. 13 1999 1385 1393
19. K.U. Birkenkamp, and P.J. Coffer Regulation of cell survival and proliferation by the FOXO (forkhead box, class O) subfamily of forkhead transcription factors Biochem. Soc. Trans. 31 2003 292 297
20. L.P. Van der Heide The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation Biochem. J. 380 2004 297 309
21. K. Howitz Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan Nature 425 2003 191 196
22. S.D. Tyner p53 mutant mice that display early ageing-associated phenotypes Nature 415 2002 45 52
23. H. Miyauchi Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway EMBO J. 23 2004 212 220
24. C. Kenyon Environmental factors and gene activities that influence life span D.L. Riddle C. elegans II 1997 Cold Spring Harbor Press 791 814
25. L. Partridge, and D. Gems Mechanisms of ageing: public or private? Nat. Rev. Genet. 3 2002 165 175
26. M. Tatar The endocrine regulation of aging by insulin-like signals Science 299 2003 1346 1351