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Volumn 33, Issue 9, 2002, Pages 1194-1199

Amyloid-β and τ serve antioxidant functions in the aging and Alzheimer brain

Author keywords

Alzheimer disease; Amyloid ; Antioxidant; Free radical; Phosphorylation; Redox active metals; Tau

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; TAU PROTEIN;

EID: 0036829434     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)01021-3     Document Type: Article
Times cited : (186)

References (57)
  • 1
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian Z.S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1985;1097-1105.
    • (1985) Arch. Neurol. , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 2
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra S.S., Heyman A., McKeel D., Sumi S.M., Crain B.J., Brownlee L.M., Vogel F.S., Hughes J.P., van Belle G., Berg L. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Crain, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    Van Belle, G.9    Berg, L.10
  • 3
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid β-protein: A reanalysis of a therapeutic hypothesis
    • Selkoe D.J. Alzheimer's disease results from the cerebral accumulation and cytotoxicity of amyloid β-protein a reanalysis of a therapeutic hypothesis . J. Alzheimer's Dis. 3:2001;75-81.
    • (2001) J. Alzheimer's Dis. , vol.3 , pp. 75-81
    • Selkoe, D.J.1
  • 4
    • 0031593784 scopus 로고    scopus 로고
    • Aβ associated neuropil changes: Correlation with neuronal loss and dementia
    • Knowles R.B., Gomez-Isla T., Hyman B.T. Aβ associated neuropil changes correlation with neuronal loss and dementia . J. Neuropathol. Exp. Neurol. 57:1998;1122-1130.
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 1122-1130
    • Knowles, R.B.1    Gomez-Isla, T.2    Hyman, B.T.3
  • 5
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes, phenotypes, and treatments
    • Selkoe D.J. Alzheimer's disease genotypes, phenotypes, and treatments . Science. 275:1997;630-631.
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 6
    • 0034502428 scopus 로고    scopus 로고
    • Arson: Tracking the culprit in Alzheimer's disease
    • Smith M.A., Joseph J.A., Perry G. Arson tracking the culprit in Alzheimer's disease . Ann. NY Acad. Sci. 924:2000;35-38.
    • (2000) Ann. NY Acad. Sci. , vol.924 , pp. 35-38
    • Smith, M.A.1    Joseph, J.A.2    Perry, G.3
  • 9
    • 0029076397 scopus 로고
    • Non-enzymatically glycated τ in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide
    • Yan S.D., Yan S.F., Chen X., Fu J., Chen M., Kuppusamy P., Smith M.A., Perry G., Godman G.C., Nawroth P. Non-enzymatically glycated τ in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide. Nat. Med. 1:1995;693-699.
    • (1995) Nat. Med. , vol.1 , pp. 693-699
    • Yan, S.D.1    Yan, S.F.2    Chen, X.3    Fu, J.4    Chen, M.5    Kuppusamy, P.6    Smith, M.A.7    Perry, G.8    Godman, G.C.9    Nawroth, P.10
  • 12
    • 0025733411 scopus 로고
    • Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures
    • Pike C.J., Walencewicz A.J., Glabe C.G., Cotman C.W. Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. Eur. J. Pharmacol. 207:1991;367-368.
    • (1991) Eur. J. Pharmacol. , vol.207 , pp. 367-368
    • Pike, C.J.1    Walencewicz, A.J.2    Glabe, C.G.3    Cotman, C.W.4
  • 13
    • 0023737806 scopus 로고
    • A4 amyloid protein deposition and the diagnosis of Alzheimer's disease: Prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques
    • Davies L., Wolska B., Hilbich C., Multhaup G., Martins R., Simms G., Beyreuther K., Masters C.L. A4 amyloid protein deposition and the diagnosis of Alzheimer's disease prevalence in aged brains determined by immunocytochemistry compared with conventional neuropathologic techniques . Neurology. 38:1988;1688-1693.
    • (1988) Neurology , vol.38 , pp. 1688-1693
    • Davies, L.1    Wolska, B.2    Hilbich, C.3    Multhaup, G.4    Martins, R.5    Simms, G.6    Beyreuther, K.7    Masters, C.L.8
  • 15
    • 16944365745 scopus 로고    scopus 로고
    • Enhanced production and oligomerization of the 42-residue amyloid beta- protein by Chinese hamster ovary cells stably expressing mutant presenilins
    • Xia W., Zhang J., Kholodenko D., Citron M., Podlisny M.B., Teplow D.B., Haass C., Seubert P., Koo E.H., Selkoe D.J. Enhanced production and oligomerization of the 42-residue amyloid beta- protein by Chinese hamster ovary cells stably expressing mutant presenilins. J. Biol. Chem. 272:1997;7977-7982.
    • (1997) J. Biol. Chem. , vol.272 , pp. 7977-7982
    • Xia, W.1    Zhang, J.2    Kholodenko, D.3    Citron, M.4    Podlisny, M.B.5    Teplow, D.B.6    Haass, C.7    Seubert, P.8    Koo, E.H.9    Selkoe, D.J.10
  • 16
    • 0037041426 scopus 로고    scopus 로고
    • Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
    • Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416:2002;535-539.
    • (2002) Nature , vol.416 , pp. 535-539
    • Walsh, D.M.1    Klyubin, I.2    Fadeeva, J.V.3    Cullen, W.K.4    Anwyl, R.5    Wolfe, M.S.6    Rowan, M.J.7    Selkoe, D.J.8
  • 17
    • 0032189767 scopus 로고    scopus 로고
    • Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits
    • Joseph J.A., Shukitt-Hale B., Denisova N.A., Prior R.L., Cao G., Martin A., Taglialatela G., Bickford P.C. Long-term dietary strawberry, spinach, or vitamin E supplementation retards the onset of age-related neuronal signal-transduction and cognitive behavioral deficits. J. Neurosci. 18:1998;8047-8055.
    • (1998) J. Neurosci. , vol.18 , pp. 8047-8055
    • Joseph, J.A.1    Shukitt-Hale, B.2    Denisova, N.A.3    Prior, R.L.4    Cao, G.5    Martin, A.6    Taglialatela, G.7    Bickford, P.C.8
  • 18
    • 0033568849 scopus 로고    scopus 로고
    • Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
    • Joseph J.A., Shukitt-Hale B., Denisova N.A., Bielinski D., Martin A., McEwen J.J., Bickford P.C. Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation. J. Neurosci. 19:1999;8114-8121.
    • (1999) J. Neurosci. , vol.19 , pp. 8114-8121
    • Joseph, J.A.1    Shukitt-Hale, B.2    Denisova, N.A.3    Bielinski, D.4    Martin, A.5    McEwen, J.J.6    Bickford, P.C.7
  • 23
    • 0031944692 scopus 로고    scopus 로고
    • Evidence of oxidative stress and in vivo neurotoxicity of β-amyloid in a transgenic mouse model of Alzheimer's disease: A chronic oxidative paradigm for testing antioxidant therapies in vivo
    • Pappolla M.A., Chyan Y.-J., Omar R.A., Hsiao K., Perry G., Smith M.A., Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of β-amyloid in a transgenic mouse model of Alzheimer's disease a chronic oxidative paradigm for testing antioxidant therapies in vivo . Am. J. Pathol. 152:1998;871-877.
    • (1998) Am. J. Pathol. , vol.152 , pp. 871-877
    • Pappolla, M.A.1    Chyan, Y.-J.2    Omar, R.A.3    Hsiao, K.4    Perry, G.5    Smith, M.A.6    Bozner, P.7
  • 25
    • 0035875690 scopus 로고    scopus 로고
    • Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis
    • Praticó D., Uryu U., Leight S., Trojanowski J.Q., Lee V.M.-Y. Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis. J. Neurosci. 21:2001;4183-4187.
    • (2001) J. Neurosci. , vol.21 , pp. 4183-4187
    • Praticó, D.1    Uryu, U.2    Leight, S.3    Trojanowski, J.Q.4    Lee, V.M.-Y.5
  • 27
    • 0023140474 scopus 로고
    • Ubiquitin is a component of paired helical filaments in Alzheimer's disease
    • Mori H., Kondo J., Ihara Y. Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science. 235:1987;1641-1644.
    • (1987) Science , vol.235 , pp. 1641-1644
    • Mori, H.1    Kondo, J.2    Ihara, Y.3
  • 28
    • 0001521232 scopus 로고
    • Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains
    • Perry G., Friedman R., Shaw G., Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc. Natl. Acad. Sci. USA. 84:1987;3033-3036.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3033-3036
    • Perry, G.1    Friedman, R.2    Shaw, G.3    Chau, V.4
  • 30
    • 0026635173 scopus 로고
    • Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid
    • Frautschy S.A., Cole G.M., Baird A. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am. J. Pathol. 140:1992;1389-1399.
    • (1992) Am. J. Pathol. , vol.140 , pp. 1389-1399
    • Frautschy, S.A.1    Cole, G.M.2    Baird, A.3
  • 32
    • 18144453796 scopus 로고    scopus 로고
    • Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease
    • DeWitt D.A., Perry G., Cohen M., Doller C., Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp. Neurol. 149:1998;329-340.
    • (1998) Exp. Neurol. , vol.149 , pp. 329-340
    • DeWitt, D.A.1    Perry, G.2    Cohen, M.3    Doller, C.4    Silver, J.5
  • 33
    • 0033401851 scopus 로고    scopus 로고
    • In vitro and in vivo protein oxidation induced by Alzheimer's disease amyloid β-peptide (1-42)
    • Butterfield D.A., Yatin S.M., Link C.D. In vitro and in vivo protein oxidation induced by Alzheimer's disease amyloid β-peptide (1-42). Ann. NY Acad. Sci. 893:1999;265-268.
    • (1999) Ann. NY Acad. Sci. , vol.893 , pp. 265-268
    • Butterfield, D.A.1    Yatin, S.M.2    Link, C.D.3
  • 34
    • 0032867538 scopus 로고    scopus 로고
    • Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease
    • Butterfield D.A., Yatin S.M., Varadarajan S., Koppal T. Amyloid beta-peptide-associated free radical oxidative stress, neurotoxicity, and Alzheimer's disease. Methods Enzymol. 309:1999;746-768.
    • (1999) Methods Enzymol , vol.309 , pp. 746-768
    • Butterfield, D.A.1    Yatin, S.M.2    Varadarajan, S.3    Koppal, T.4
  • 35
    • 0031589214 scopus 로고    scopus 로고
    • Alzheimer's disease amyloid beta peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions
    • Walter M.F., Mason P.E., Mason R.P. Alzheimer's disease amyloid beta peptide 25-35 inhibits lipid peroxidation as a result of its membrane interactions. Biochem. Biophys. Res. Commun. 233:1997;760-764.
    • (1997) Biochem. Biophys. Res. Commun. , vol.233 , pp. 760-764
    • Walter, M.F.1    Mason, P.E.2    Mason, R.P.3
  • 40
    • 0036955813 scopus 로고    scopus 로고
    • Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation
    • Kril J.J., Patel S., Harding A.J., Halliday G.M. Neuron loss from the hippocampus of Alzheimer's disease exceeds extracellular neurofibrillary tangle formation. Acta Neuropathol. (Berl.). 103:2002;370-376.
    • (2002) Acta Neuropathol. (Berl.) , vol.103 , pp. 370-376
    • Kril, J.J.1    Patel, S.2    Harding, A.J.3    Halliday, G.M.4
  • 43
    • 0030989545 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease
    • Sayre L.M., Zelasko D.A., Harris P.L.R., Perry G., Salomon R.G., Smith M.A. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J. Neurochem. 68:1997;2092-2097.
    • (1997) J. Neurochem. , vol.68 , pp. 2092-2097
    • Sayre, L.M.1    Zelasko, D.A.2    Harris, P.L.R.3    Perry, G.4    Salomon, R.G.5    Smith, M.A.6
  • 44
    • 0033836580 scopus 로고    scopus 로고
    • In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of τ induced by 4-hydroxy-2-nonenal modification
    • Takeda A., Smith M.A., Avilá J., Nunomura A., Siedlak S.L., Zhu X., Perry G., Sayre L.M. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of τ induced by 4-hydroxy-2-nonenal modification. J. Neurochem. 75:2000;1234-1241.
    • (2000) J. Neurochem. , vol.75 , pp. 1234-1241
    • Takeda, A.1    Smith, M.A.2    Avilá, J.3    Nunomura, A.4    Siedlak, S.L.5    Zhu, X.6    Perry, G.7    Sayre, L.M.8
  • 45
    • 0032905632 scopus 로고    scopus 로고
    • Protein-bound acrolein: A novel marker of oxidative stress in Alzheimer's disease
    • Calingasan N.Y., Uchida K., Gibson G.E. Protein-bound acrolein a novel marker of oxidative stress in Alzheimer's disease . J. Neurochem. 72:1999;751-756.
    • (1999) J. Neurochem. , vol.72 , pp. 751-756
    • Calingasan, N.Y.1    Uchida, K.2    Gibson, G.E.3
  • 46
  • 48
    • 0033782845 scopus 로고    scopus 로고
    • Activation of p38 kinase links τ phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
    • Zhu X., Rottkamp C.A., Boux H., Takeda A., Perry G., Smith M.A. Activation of p38 kinase links τ phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J. Neuropathol. Exp. Neurol. 59:2000;880-888.
    • (2000) J. Neuropathol. Exp. Neurol. , vol.59 , pp. 880-888
    • Zhu, X.1    Rottkamp, C.A.2    Boux, H.3    Takeda, A.4    Perry, G.5    Smith, M.A.6
  • 49
  • 50
    • 0035142804 scopus 로고    scopus 로고
    • Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease
    • Zhu X., Raina A.K., Rottkamp C.A., Aliev G., Perry G., Boux H., Smith M.A. Activation and redistribution of c-Jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J. Neurochem. 76:2001;435-441.
    • (2001) J. Neurochem. , vol.76 , pp. 435-441
    • Zhu, X.1    Raina, A.K.2    Rottkamp, C.A.3    Aliev, G.4    Perry, G.5    Boux, H.6    Smith, M.A.7
  • 54
    • 0033922393 scopus 로고    scopus 로고
    • Phosphorylation of τ alters its association with the plasma membrane
    • Ekinci F.J., Shea T.B. Phosphorylation of τ alters its association with the plasma membrane. Cell. Mol. Neurobiol. 20:2000;497-508.
    • (2000) Cell. Mol. Neurobiol. , vol.20 , pp. 497-508
    • Ekinci, F.J.1    Shea, T.B.2
  • 56
    • 0037172424 scopus 로고    scopus 로고
    • Predicting the failure of the amyloid-β vaccine
    • Smith M.A., Atwood C.S., Joseph J.A., Perry G. Predicting the failure of the amyloid-β vaccine. Lancet. 359:2002;1864-1865.
    • (2002) Lancet , vol.359 , pp. 1864-1865
    • Smith, M.A.1    Atwood, C.S.2    Joseph, J.A.3    Perry, G.4
  • 57
    • 0035997240 scopus 로고    scopus 로고
    • The state versus amyloid-β: The trial of the most wanted criminal in Alzheimer disease
    • Rottkamp C.A., Atwood C.S., Joseph J.A., Nunomura A., Perry G., Smith M.A. The state versus amyloid-β the trial of the most wanted criminal in Alzheimer disease . Peptides. 23:2002;1333-1341.
    • (2002) Peptides , vol.23 , pp. 1333-1341
    • Rottkamp, C.A.1    Atwood, C.S.2    Joseph, J.A.3    Nunomura, A.4    Perry, G.5    Smith, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.