-
1
-
-
0035852715
-
Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3
-
Anderson M.J., Shelton G.D., Cavenee W.K., Arden K.C. Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3. Proc. Natl. Acad. Sci. USA. 98:2001;1589-1594
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1589-1594
-
-
Anderson, M.J.1
Shelton, G.D.2
Cavenee, W.K.3
Arden, K.C.4
-
2
-
-
0037323903
-
Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors
-
Birkenkamp K.U., Coffer P.J. Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors. Biochem. Soc. Trans. 31:2003;292-297
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 292-297
-
-
Birkenkamp, K.U.1
Coffer, P.J.2
-
3
-
-
0037416153
-
FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts
-
Bois P.R., Grosveld G.C. FKHR (FOXO1a) is required for myotube fusion of primary mouse myoblasts. EMBO J. 22:2003;1147-1157
-
(2003)
EMBO J.
, vol.22
, pp. 1147-1157
-
-
Bois, P.R.1
Grosveld, G.C.2
-
4
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A., Sweeney L.B., Sturgill J.F., Chua K.F., Greer P.L., Lin Y., Tran H., Ross S.E., Mostoslavsky R., Cohen H.Y., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science. 303:2004;2011-2015
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
5
-
-
0036629251
-
Cell cycle and death control: Long live Forkheads
-
Burgering B.M., Kops G.J. Cell cycle and death control. long live Forkheads Trends Biochem. Sci. 27:2002;352-360
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 352-360
-
-
Burgering, B.M.1
Kops, G.J.2
-
6
-
-
0037464510
-
Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults
-
Calle E.E., Rodriguez C., Walker-Thurmond K., Thun M.J. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N. Engl. J. Med. 348:2003;1625-1638
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 1625-1638
-
-
Calle, E.E.1
Rodriguez, C.2
Walker-Thurmond, K.3
Thun, M.J.4
-
7
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon D.H., Miao L., Kollipara R., Horner J.W., DePinho R.A. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science. 301:2003;215-218
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
Depinho, R.A.5
-
9
-
-
0043244921
-
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
-
Fulco M., Schiltz R.L., Iezzi S., King M.T., Zhao P., Kashiwaya Y., Hoffman E., Veech R.L., Sartorelli V. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol. Cell. 12:2003;51-62
-
(2003)
Mol. Cell
, vol.12
, pp. 51-62
-
-
Fulco, M.1
Schiltz, R.L.2
Iezzi, S.3
King, M.T.4
Zhao, P.5
Kashiwaya, Y.6
Hoffman, E.7
Veech, R.L.8
Sartorelli, V.9
-
10
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka T., Biggs W.H. 3rd, Tieu D., Boyer A.D., Varki N.M., Cavenee W.K., Arden K.C. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc. Natl. Acad. Sci. USA. 101:2004;2975-2980
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs III, W.H.2
Tieu, D.3
Boyer, A.D.4
Varki, N.M.5
Cavenee, W.K.6
Arden, K.C.7
-
11
-
-
0042477748
-
Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors
-
Hribal M.L., Nakae J., Kitamura T., Shutter J.R., Accili D. Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors. J. Cell Biol. 162:2003;535-541
-
(2003)
J. Cell Biol.
, vol.162
, pp. 535-541
-
-
Hribal, M.L.1
Nakae, J.2
Kitamura, T.3
Shutter, J.R.4
Accili, D.5
-
12
-
-
11144357466
-
IkB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu M.C.-T., Lee D.F., Xia W., Golfman L., Ou-Yang F., Hu L.S., Yang J.-Y., Zou Y., Bao S., Hanada N., et al. IkB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell. 117:2004;225-237
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.-T.1
Lee, D.F.2
Xia, W.3
Golfman, L.4
Ou-Yang, F.5
Hu, L.S.6
Yang, J.-Y.7
Zou, Y.8
Bao, S.9
Hanada, N.10
-
13
-
-
0242539698
-
The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling
-
Junger M.A., Rintelen F., Stocker H., Wasserman J.D., Vegh M., Radimerski T., Greenberg M.E., Hafen E. The Drosophila Forkhead transcription factor FOXO mediates the reduction in cell number associated with reduced insulin signaling. J. Biol. 2:2003;20
-
(2003)
J. Biol.
, vol.2
, pp. 20
-
-
Junger, M.A.1
Rintelen, F.2
Stocker, H.3
Wasserman, J.D.4
Vegh, M.5
Radimerski, T.6
Greenberg, M.E.7
Hafen, E.8
-
14
-
-
0347747970
-
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
-
Kau T.R., Schroeder F., Ramaswamy S., Wojciechowski C.L., Zhao J.J., Roberts T.M., Clardy J., Sellers W.R., Silver P.A. A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells. Cancer Cell. 4:2003;463-476
-
(2003)
Cancer Cell
, vol.4
, pp. 463-476
-
-
Kau, T.R.1
Schroeder, F.2
Ramaswamy, S.3
Wojciechowski, C.L.4
Zhao, J.J.5
Roberts, T.M.6
Clardy, J.7
Sellers, W.R.8
Silver, P.A.9
-
15
-
-
0036950665
-
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth
-
Kitamura T., Nakae J., Kitamura Y., Kido Y., Biggs W.H. 3rd, Wright C.V., White M.F., Arden K.C., Accili D. The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth. J. Clin. Invest. 110:2002;1839-1847
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1839-1847
-
-
Kitamura, T.1
Nakae, J.2
Kitamura, Y.3
Kido, Y.4
Biggs III, W.H.5
Wright, C.V.6
White, M.F.7
Arden, K.C.8
Accili, D.9
-
16
-
-
0036787919
-
Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors
-
Lagutina I., Conway S.J., Sublett J., Grosveld G.C. Pax3-FKHR knock-in mice show developmental aberrations but do not develop tumors. Mol. Cell. Biol. 22:2002;7204-7216
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7204-7216
-
-
Lagutina, I.1
Conway, S.J.2
Sublett, J.3
Grosveld, G.C.4
-
17
-
-
0037466652
-
DAF-16 target genes that control C. elegans life-span and metabolism
-
Lee S.S., Kennedy S., Tolonen A.C., Ruvkun G. DAF-16 target genes that control C. elegans life-span and metabolism. Science. 300:2003;644-647
-
(2003)
Science
, vol.300
, pp. 644-647
-
-
Lee, S.S.1
Kennedy, S.2
Tolonen, A.C.3
Ruvkun, G.4
-
18
-
-
0033785487
-
Role of the forkhead transcription family member, FKHR, in thymocyte differentiation
-
Leenders H., Whiffield S., Benoist C., Mathis D. Role of the forkhead transcription family member, FKHR, in thymocyte differentiation. Eur. J. Immunol. 30:2000;2980-2990
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2980-2990
-
-
Leenders, H.1
Whiffield, S.2
Benoist, C.3
Mathis, D.4
-
19
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell. 107:2001;137-148
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
20
-
-
0037033005
-
FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer
-
Modur V., Nagarajan R., Evers B.M., Milbrandt J. FOXO proteins regulate tumor necrosis factor-related apoptosis inducing ligand expression. Implications for PTEN mutation in prostate cancer. J. Biol. Chem. 277:2002;47928-47937
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 47928-47937
-
-
Modur, V.1
Nagarajan, R.2
Evers, B.M.3
Milbrandt, J.4
-
21
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta M.C., Divecha N., Lemieux M., Kamel C., Chen D., Gu W., Bultsma Y., McBurney M., Guarente L. Mammalian SIRT1 represses forkhead transcription factors. Cell. 116:2004;551-563
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
22
-
-
0042092531
-
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy C.T., McCarroll S.A., Bargmann C.I., Fraser A., Kamath R.S., Ahringer J., Li H., Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature. 424:2003;277-283
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
McCarroll, S.A.2
Bargmann, C.I.3
Fraser, A.4
Kamath, R.S.5
Ahringer, J.6
Li, H.7
Kenyon, C.8
-
23
-
-
0036787607
-
Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1
-
Nakae J., Biggs W.H., Kitamura T., Cavenee W.K., Wright C.V., Arden K.C., Accili D. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat. Genet. 32:2002;245-253
-
(2002)
Nat. Genet.
, vol.32
, pp. 245-253
-
-
Nakae, J.1
Biggs, W.H.2
Kitamura, T.3
Cavenee, W.K.4
Wright, C.V.5
Arden, K.C.6
Accili, D.7
-
24
-
-
0037237279
-
The forkhead transcription factor foxo1 regulates adipocyte differentiation
-
Nakae J., Kitamura T., Kitamura Y., Biggs W.H., Arden K.C., Accili D. The forkhead transcription factor foxo1 regulates adipocyte differentiation. Dev. Cell. 4:2003;119-129
-
(2003)
Dev. Cell
, vol.4
, pp. 119-129
-
-
Nakae, J.1
Kitamura, T.2
Kitamura, Y.3
Biggs, W.H.4
Arden, K.C.5
Accili, D.6
-
25
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North B.J., Marshall B.L., Borra M.T., Denu J.M., Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell. 11:2003;437-444
-
(2003)
Mol. Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
26
-
-
0042161896
-
Control of cell number by Drosophila FOXO: Downstream and feedback regulation of the insulin receptor pathway
-
Puig O., Marr M.T., Ruhf M.L., Tjian R. Control of cell number by Drosophila FOXO. downstream and feedback regulation of the insulin receptor pathway Genes Dev. 17:2003;2006-2020
-
(2003)
Genes Dev.
, vol.17
, pp. 2006-2020
-
-
Puig, O.1
Marr, M.T.2
Ruhf, M.L.3
Tjian, R.4
-
27
-
-
0038187621
-
Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction
-
Puigserver P., Rhee J., Donovan J., Walkey C.J., Yoon J.C., Oriente F., Kitamura Y., Altomonte J., Dong H., Accili D., Spiegelman B.M. Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction. Nature. 423:2003;550-555
-
(2003)
Nature
, vol.423
, pp. 550-555
-
-
Puigserver, P.1
Rhee, J.2
Donovan, J.3
Walkey, C.J.4
Yoon, J.C.5
Oriente, F.6
Kitamura, Y.7
Altomonte, J.8
Dong, H.9
Accili, D.10
Spiegelman, B.M.11
-
28
-
-
0347384010
-
The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo
-
Relaix F., Polimeni M., Rocancourt D., Ponzetto C., Schafer B.W., Buckingham M. The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo. Genes Dev. 17:2003;2950-2965
-
(2003)
Genes Dev.
, vol.17
, pp. 2950-2965
-
-
Relaix, F.1
Polimeni, M.2
Rocancourt, D.3
Ponzetto, C.4
Schafer, B.W.5
Buckingham, M.6
-
29
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri M., Sandri C., Gilbert A., Skurk C., Calabria E., Picard A., Walsh K., Schiaffino S., Lecker S.H., Goldberg A.L. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell. 117:2004;399-412
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skurk, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
30
-
-
1642332084
-
Integration of Smad and Forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation
-
Seoane J., Le H.-V., Shen L., Anderson S.A., Massagué J. Integration of Smad and Forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation. Cell. 117:2004;211-223
-
(2004)
Cell
, vol.117
, pp. 211-223
-
-
Seoane, J.1
Le H., -V.2
Shen, L.3
Anderson, S.A.4
Massagué, J.5
-
31
-
-
0037438589
-
Common mechanism for oncogenic activation of MLL by forkhead family proteins
-
So C.W., Cleary M.L. Common mechanism for oncogenic activation of MLL by forkhead family proteins. Blood. 101:2003;633-639
-
(2003)
Blood
, vol.101
, pp. 633-639
-
-
So, C.W.1
Cleary, M.L.2
-
32
-
-
0347457075
-
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
-
Starai V.J., Celic I., Cole R.N., Boeke J.D., Escalante-Semerena J.C. Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine. Science. 298:2002;2390-2392
-
(2002)
Science
, vol.298
, pp. 2390-2392
-
-
Starai, V.J.1
Celic, I.2
Cole, R.N.3
Boeke, J.D.4
Escalante-Semerena, J.C.5
-
33
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligasaes by inhibiting Foxo transcription factors
-
in press.
-
Stitt, T.N., Drujan, D., Clarke, B.A., and Panaro, F.T.Y., Kline, W.O., Gonzales, M., Yancopoulos, G.D., and Glass, D.J. (2004). The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligasaes by inhibiting Foxo transcription factors. Mol. Cell 14, in press.
-
(2004)
Mol. Cell
, vol.14
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.T.Y.4
Kline, W.O.5
Gonzales, M.6
Yancopoulos, G.D.7
Glass, D.J.8
-
34
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell. 107:2001;149-159
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
36
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of 1(kappa)B kinase-beta
-
Yin M.J., Yamamoto Y., Gaynor R.B. The anti-inflammatory agents aspirin and salicylate inhibit the activity of 1(kappa)B kinase-beta. Nature. 396:1998;77-80
-
(1998)
Nature
, vol.396
, pp. 77-80
-
-
Yin, M.J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
37
-
-
0035979775
-
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
-
Yuan M., Konstantopoulos N., Lee J., Hansen L., Li Z.W., Karin M., Shoelson S.E. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta. Science. 293:2001;1673-1677
-
(2001)
Science
, vol.293
, pp. 1673-1677
-
-
Yuan, M.1
Konstantopoulos, N.2
Lee, J.3
Hansen, L.4
Li, Z.W.5
Karin, M.6
Shoelson, S.E.7
|