Biallelic Inactivation of Fumarate Hydratase (FH) Occurs in Nonsyndromic Uterine Leiomyomas but Is Rare in Other Tumors

American Journal of Pathology

Volumn 164, Issue 1, 2004, Pages 17-22

  Lehtonen, Rainer ^a   Kiuru, Maija ^a   Vanharanta, Sakari ^a   Sjöberg, Jari ^b   Aaltonen, Leena Maija ^a,b   Aittomäki, Kristiina ^a,b   Arola, Johanna ^a   Butzow, Ralf ^a,b   Eng, Charis ^g   Husgafvel Pursiainen, Kirsti ^c   Isola, Jorma ^d   Järvinen, Heikki ^b   Koivisto, Pasi ^e   Mecklin, Jukka Pekka ^f   Peltomäki, Päivi ^a   Salovaara, Reijo ^a   Wasenius, Veli Matti ^b   Karhu, Auli ^a   Launonen, Virpi ^a   Nupponen, Nina N ^a   Aaltonen, Lauri A ^a,h   more..

^a UNIVERSITY OF HELSINKI   (Finland)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^d TAMPERE UNIVERSITY HOSPITAL   (Finland)

^e TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^f JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^g OHIO STATE UNIVERSITY   (United States)

^h UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; FUMARATE HYDRATASE; THREONINE;

ALLELE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; EXON; FEMALE; GENE DELETION; GENE INACTIVATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC PREDISPOSITION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; LEIOMYOSARCOMA; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PAPILLARY CARCINOMA; PRIORITY JOURNAL; SOMATIC MUTATION; UTERUS MYOMA; COMPARATIVE STUDY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEIOMYOMA; MALE; MUTATION; POLYMERASE CHAIN REACTION; UTERUS CANCER;

BASE SEQUENCE; CARCINOMA, RENAL CELL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA MUTATIONAL ANALYSIS; FEMALE; FUMARATE HYDRATASE; HUMANS; LEIOMYOMA; LOSS OF HETEROZYGOSITY; MALE; MUTATION; POLYMERASE CHAIN REACTION; UTERINE NEOPLASMS;

EID: 1542469716     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63091-X     Document Type: Article

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