Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 3, 2003, Pages 1116-1121

  Zhang, Jin ^a   Asin Cayuela, Jordi ^a   Fish, Jennifer ^a   Michikawa, Yuichi ^a,e   Bonafé, Massimiliano ^b   Olivieri, Fabiola ^c   Passarino, Giuseppe ^d   De Benedictis, Giovanna ^d   Franceschi, Claudio ^b   Attardi, Giuseppe ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c INRCA   (Italy)

^d UNIVERSITY OF CALABRIA   (Italy)

^e NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOCHONDRIAL DNA;

AGED; AGING; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; DIZYGOTIC TWINS; DNA REPLICATION; DNA SCREENING; DNA STRAND; DNA SYNTHESIS; FEMALE; FIBROBLAST; GENE CONTROL; GENE MUTATION; HUMAN; HUMAN CELL; LEUKOCYTE; LONGEVITY; MAJOR CLINICAL STUDY; MALE; MONOZYGOTIC TWINS; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOMATIC CELL GENETICS; SURVIVAL; TWINS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; ALLELES; DNA, MITOCHONDRIAL; FEMALE; FIBROBLASTS; GENE LIBRARY; GRANULOCYTES; HUMANS; LEUKOCYTES; LONGEVITY; LYMPHOCYTES; MALE; MIDDLE AGED; MODELS, GENETIC; MONOCYTES; MUTATION; REPLICATION ORIGIN; TWIN STUDIES; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 0037417898     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.242719399     Document Type: Article

References (24)

1. Michikawa, Y., Mazzucchelli, F., Bresolin, N., Scarlato, G. & Attardi, G. (1999) Science 286, 774-779.
2. Wang, Y., Michikawa, Y., Mallidis, C., Bai, Y., Woodhouse, L., Kevin, E., Yarasheski, K. E., Miller, C. A., Askanas, V., Engel, W. K., et al. (2001) Proc. Natl. Acad. Sci. USA 98, 4022-4027.
3. Michikawa, Y., Laderman, K., Richter, K. & Attardi, G. (2002) Somatic Cell Mol. Genet. 25, 333-342.
4. Attardi, G. (1985) Int. Rev. Cytol. 93, 93-145.
5. Chang, D. D. & Clayton, D. A. (1985) Proc. Natl. Acad. Sci. USA 82, 351-355.
6. Walberg, M. W. & Clayton, D. A. (1981) Nucleic Acids Res. 9, 5411-5421.
7. Boyum, A. (1964) Nature 204, 793-794.
8. Boyum, A. (1968) Scand. J. Clin. Lab. Invest. 21 (Suppl. 97), 9-29.
9. Boyum, A. (1968) Scand. J. Clin. Lab. Invest. 21 (Suppl. 97), 50.
10. Louie, L. G. & King, M. C. (1991) Am. J. Hum. Genet. 48, 637-638.
11. Anderson, S., Bakier, A. T., Barrell, B. G., de-Bruijn, M. H. L., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., Sanger, F., et al. (1981) Nature 290, 457-465.
12. Michikawa, Y. & Attardi, G. (2002) in Methods in Molecular Biology, ed. Copeland, W. C. (Humana, Totowa, NJ), Vol. 197, pp. 75-92.
13. Hothaus, G. & Attardi, G. (1995) Mol. Cell. Biol. 15, 964-974.
14. Crews, S., Ojala, D., Posakony, J., Nichiguchi, J. & Attardi, G. (1979) Nature 277, 192-198.
15. Kang, D., Miyako, K., Kai, Y., Irie, T. & Takeshige, K. (1997) J. Biol. Chem. 272, 15275-15279.
16. MITOMAP: A Human Mitochondrial Genome Database (2002) www.mitomap.org.
17. Bonafé, M., Cardelli, M., Marchegiani, F., Cavallone, L., Giovagnetti, S., Olivieri, F., Lisa, R., Pieri, C. & Franceschi, C. (2001) Exp. Gerontol. 36, 1063-1073.
18. Slagboom, P. E., Droog, S. & Boomsma, D. I. (1994) Am. J. Hum. Genet. 55, 876-882.
19. Spellacy, W. N., Handler, A. & Ferre, C. D. (1990) Obstet. Gynecol. 75, 168-171.
20. Kiley, J. (1990) Bull. N.Y. Acad. Med. 66, 618-637.
21. Kinzler, W. L., Ananth, C. V. & Vintzileos, A. M. (2000) J. Soc. Gynecol. Invest. 7, 321-327.
22. Flory, P. J., Jr., & Vinograd, J. (1973) J. Mol. Biol. 74, 81-94.
23. Wiseman, A. & Attardi, G. (1978) Mol. Gen. Genet. 167, 51-63.
24. Laderman, K. A., Penny, J. R., Mazzucchelli, F., Bresolin, N., Scarlato, G. & Attardi, G. (1996) J. Biol. Chem. 271, 15891-15897.