Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture

Neurobiology of Disease

Volumn 15, Issue 1, 2004, Pages 29-39

  Trimmer, Patricia A ^b   Keeney, Paula M ^b   Borland, M Kate ^b   Simon, Frederic A ^b   Almeida, Jatanna ^b   Swerdlow, Russell H ^b   Parks, Janice P ^b   Parker Jr , W Davis ^b   Bennett Jr , James P ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b NONE

Author keywords

Alzheimer's disease; Bioenergetic phenotype; Cybrids; mtDNA; Replicative advantage

Indexed keywords

BROXURIDINE; CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA;

ALZHEIMER DISEASE; ARTICLE; BIOENERGY; CELL COUNT; CELL CULTURE; CELL DAMAGE; CELL FUNCTION; CELL METABOLISM; CELL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYBRID; DISEASE EXACERBATION; DNA REPLICATION; ENZYME ACTIVITY; EXPERIMENTAL MODEL; GENE DELETION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; MEMBRANE POTENTIAL; MITOCHONDRIAL GENETICS; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SAMPLING; THROMBOCYTE;

EID: 1642578313     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2003.09.011     Document Type: Article

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