Prodrugs in genetic chemoradiotherapy

Current Pharmaceutical Design

Volumn 9, Issue 26, 2003, Pages 2131-2154

  Patterson, Adam V ^a   Saunders, Mark P ^b   Greco, Olga ^c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c WAYNE STATE UNIVERSITY   (United States)

Author keywords

GDEPT; Gene therapy; Molecular chemotherapy; Prodrugs; Radiosensitization; Radiotherapy; Suicide genes

Indexed keywords

1,4 BIS[[2 (DIMETHYLAMINO N OXIDE)ETHYL]AMINO] 5,8 DIHYDROXYANTHRAQUINONE; 5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; 5 (2 BROMOVINYL) 2' DEOXYURIDINE; ACICLOVIR; ANTINEOPLASTIC AGENT; AZIRIDINE DERIVATIVE; CAPECITABINE; CARBOXYPEPTIDASE G2; CISPLATIN; CYCLOPHOSPHAMIDE; CYTARABINE; CYTOCHROME P450 2B1; CYTOSINE DEAMINASE; CYTOTOXIC AGENT; DEOXYCYTIDINE KINASE; FLUCYTOSINE; FLUOROURACIL; GANCICLOVIR; GEMCITABINE; HORSERADISH PEROXIDASE; IFOSFAMIDE; INDOLEACETIC ACID; IRINOTECAN; MITOMYCIN C; N [4 [(2 CHLOROETHYL)(2 MESYLOXYETHYL)AMINO]BENZOYL]GLUTAMIC ACID; NITROREDUCTASE; PRODRUG; RADIOSENSITIZING AGENT; THYMIDINE KINASE; UNINDEXED DRUG;

ANTINEOPLASTIC ACTIVITY; BYSTANDER EFFECT; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CYTOTOXICITY; DNA MODIFICATION; DRUG DIFFUSION; DRUG STRUCTURE; ESCHERICHIA COLI; GENE DIRECTED ENZYME PRODRUG THERAPY; GENE TARGETING; GENE THERAPY; HERPES SIMPLEX VIRUS; HUMAN; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RADIOSENSITIZATION; RETROSPECTIVE STUDY; REVIEW; RNA TRANSLATION; SOLID TUMOR; SUICIDE GENE; TARGET CELL;

ANIMALS; COMBINED MODALITY THERAPY; ENZYMES; GENE THERAPY; HUMANS; NEOPLASMS; PRODRUGS; RADIATION-SENSITIZING AGENTS; RADIOTHERAPY, ADJUVANT;

EID: 0141649374     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/1381612033454117     Document Type: Review

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