-
1
-
-
0034635057
-
Human gene marker/therapy clinical protocols
-
Human gene marker/therapy clinical protocols. Hum. Gene Ther., 11: 2543-2619, 2000.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2543-2619
-
-
-
2
-
-
0035123128
-
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
-
DOI 10.1002/1097-4652(2001)9999:9999<::AID-JCP1060
-
Greco, O., and Dachs, G. U. Gene-directed enzyme/prodrug therapy of cancer: historical appraisal and future prospectives. J. Cell. Physiol., 187: 22-36, 2001. (Pubitemid 32195242)
-
(2001)
Journal of Cellular Physiology
, vol.187
, Issue.1
, pp. 22-36
-
-
Greco, O.1
Dachs, G.U.2
-
3
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten, F. L. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res., 46: 5276-5281, 1986. (Pubitemid 16008301)
-
(1986)
Cancer Research
, vol.46
, Issue.10
, pp. 5276-5281
-
-
Moolten, F.L.1
-
4
-
-
0033664464
-
Development of a novel enzyme/prodrug combination for gene therapy of cancer: Horseradish peroxidase/indole-3-acetic acid
-
Greco, O., Folkes, L. K., Wardman, P., Tozer, G. M., and Dachs, G. U. Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid. Cancer Gene Ther., 7: 1414-1420, 2000.
-
(2000)
Cancer Gene Ther.
, vol.7
, pp. 1414-1420
-
-
Greco, O.1
Folkes, L.K.2
Wardman, P.3
Tozer, G.M.4
Dachs, G.U.5
-
5
-
-
0033867776
-
Hypoxia modulated gene expression: Angiogenesis, metastasis and therapeutic exploitation
-
DOI 10.1016/S0959-8049(00)00159-3, PII S0959804900001593
-
Dachs, G. U., and Tozer, G. M. Hypoxia modulated gene expression: angiogenesis, metastasis and therapeutic exploitation. Eur. J. Cancer, 36: 1649-1660, 2000. (Pubitemid 30616369)
-
(2000)
European Journal of Cancer
, vol.36
, Issue.13
, pp. 1649-1660
-
-
Dachs, G.U.1
Tozer, G.M.2
-
6
-
-
0035863281
-
Oxidative activation of indole-3-acetic acids to cytotoxic species - A potential new role for plant auxins in cancer therapy
-
DOI 10.1016/S0006-2952(00)00498-6, PII S0006295200004986
-
Folkes, L. K., and Wardman, P. Oxidative activation of indole-3-acetic acids to cytotoxic species: a potential new role for plant auxins in cancer therapy. Biochem. Pharmacol., 61: 129-136, 2001. (Pubitemid 32121777)
-
(2001)
Biochemical Pharmacology
, vol.61
, Issue.2
, pp. 129-136
-
-
Folkes, L.K.1
Wardman, P.2
-
7
-
-
0030024847
-
Antibody-enzyme conjugates for cancer therapy
-
DOI 10.1093/jnci/88.3-4.153
-
Melton, R. G., and Sherwood, R. F. Antibody-enzyme conjugates for cancer therapy. J. Natl. Cancer Inst. (Bethesda), 88: 153-165, 1996. (Pubitemid 26065827)
-
(1996)
Journal of the National Cancer Institute
, vol.88
, Issue.3-4
, pp. 153-165
-
-
Melton, R.G.1
Sherwood, R.F.2
-
8
-
-
0029164573
-
The chemotherapy of colon cancer
-
Connors, T. A., Duncan, R., and Knox, R. J. The chemotherapy of colon cancer. Eur. J. Cancer, 31A: 1373-1378, 1995.
-
(1995)
Eur. J. Cancer
, vol.31 A
, pp. 1373-1378
-
-
Connors, T.A.1
Duncan, R.2
Knox, R.J.3
-
9
-
-
0000959189
-
Hypoglycemic action of indole-3-acetic acid by mouth in patients with diabetes mellitus
-
Mirsky, I. A., and Diengott, D. Hypoglycemic action of indole-3-acetic acid by mouth in patients with diabetes mellitus. Proc. Soc. Exp. Biol. Med., 93: 109-110, 1956.
-
(1956)
Proc. Soc. Exp. Biol. Med.
, vol.93
, pp. 109-110
-
-
Mirsky, I.A.1
Diengott, D.2
-
10
-
-
0031742232
-
Toward targeted 'oxidation therapy' of cancer: Peroxidase-catalysed cytotoxicity of indole-3-acetic acids
-
DOI 10.1016/S0360-3016(98)00297-1, PII S0360301698002971
-
Folkes, L. K., Candeias, L. P., and Wardman, P. Towards targeted "oxidation therapy" of cancer: peroxidase-catalyzed cytotoxicity of indole-3-acetic acids. Int. J. Radiat. Oncol. Biol. Phys., 42: 917-920, 1998. (Pubitemid 28559443)
-
(1998)
International Journal of Radiation Oncology Biology Physics
, vol.42
, Issue.4
, pp. 917-920
-
-
Folkes, L.K.1
Candeias, L.P.2
Wardman, P.3
-
11
-
-
0009415389
-
Peroxidase activity may play a role in the cytotoxic effect of indole acetic acid
-
Pires de Melo, M., Pithon Curi, T. C., Curi, R., Di Mascio, P., and Cilento, G. Peroxidase activity may play a role in the cytotoxic effect of indole acetic acid. Photochem. Photobiol., 65: 338-341, 1997.
-
(1997)
Photochem. Photobiol.
, vol.65
, pp. 338-341
-
-
Pires De Melo, M.1
Pithon Curi, T.C.2
Curi, R.3
Di Mascio, P.4
Cilento, G.5
-
12
-
-
0032189889
-
Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil
-
DOI 10.1016/S0306-3623(98)00032-9, PII S0306362398000329
-
Pires de Melo, M., Curi, T. C., Miyasaka, C. K., Palanch, A. C., and Curi, R. Effect of indole acetic acid on oxygen metabolism in cultured rat neutrophil. Gen. Pharmacol., 31: 573-578, 1998. (Pubitemid 28458926)
-
(1998)
General Pharmacology
, vol.31
, Issue.4
, pp. 573-578
-
-
De Melo, M.P.1
Curi, T.C.P.2
Miyasaka, C.K.3
Palanch, A.C.4
Curi, R.5
-
13
-
-
0026677532
-
HMEC-1: Establishment of an immortalized human microvascular endothelial cell line
-
Ades, E. W., Candal, F. J., Swerlick, R. A., George, V. G., Summers, S., Bosse, D. C., and Lawley, T. J. HMEC-1: establishment of an immortalised human microvascular endothelial cell line. J. Investig. Dermatol., 99: 683-690, 1992. (Pubitemid 23002027)
-
(1992)
Journal of Investigative Dermatology
, vol.99
, Issue.6
, pp. 683-690
-
-
Ades, E.W.1
Candal, F.J.2
Swerlick, R.A.3
George, V.G.4
Summers, S.5
Bosse, D.C.6
Lawley, T.J.7
-
14
-
-
0027997875
-
Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase
-
DOI 10.1083/jcb.127.3.641
-
Connolly, C. N., Futter, C. E., Gibson, A., Hopkins, C. R., and Cutler, D. F. Transport into and out the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase. J. Cell Biol., 127: 641-652, 1994. (Pubitemid 24332962)
-
(1994)
Journal of Cell Biology
, vol.127
, Issue.3
, pp. 641-652
-
-
Connolly, C.N.1
Futter, C.E.2
Gibson, A.3
Hopkins, C.R.4
Cutler, D.F.5
-
15
-
-
0033869074
-
Gene delivery to hypoxic cells in vitro
-
Dachs, G. U., Coralli, C., Hart, S. L., and Tozer, G. M. Gene delivery to hypoxic cells in vitro. Br. J. Cancer, 83: 662-667, 2000. (Pubitemid 30636310)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.5
, pp. 662-667
-
-
Dachs, G.U.1
Coralli, C.2
Hart, S.L.3
Tozer, G.M.4
-
16
-
-
17344374068
-
Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector
-
Hart, S. L., Arancibia-Cárcamo, C. V., Wolfert, M. A., O'Reilly, N. J., Ali, R. R., Coutelle, C., George, A. J., Harbottle, R. P., Knight, A. M., Larkin, D. F., Levinsky, R. J., Seymour, L. W., Thrasher, A. J., and Kinnon, C. Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector. Hum. Gene Ther., 9: 575-585, 1998.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 575-585
-
-
Hart, S.L.1
Arancibia-Cárcamo, C.V.2
Wolfert, M.A.3
O'Reilly, N.J.4
Ali, R.R.5
Coutelle, C.6
George, A.J.7
Harbottle, R.P.8
Knight, A.M.9
Larkin, D.F.10
Levinsky, R.J.11
Seymour, L.W.12
Thrasher, A.J.13
Kinnon, C.14
-
17
-
-
12644258541
-
2. 1. Indole-3-acetamides
-
DOI 10.1021/jm960485v
-
Dillard, R. D., Bach, N. J., Draheim, S. E., Berry, D. R., Carlson, D. G., Chirgadze, N. Y., Clawson, D. K., Hartley, L. W., Johnson, L. M., Jones, N. D., McKinney, E. R., Mihelich, E. D., Olkowski, J. L., Schevitz, R. W., Smith, A. C., Snyder, D. W., Sommers, C. D., and Wery, J. P. Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides. J. Med. Chem., 39: 5119-5136, 1996. (Pubitemid 27008959)
-
(1996)
Journal of Medicinal Chemistry
, vol.39
, Issue.26
, pp. 5119-5136
-
-
Dillard, R.D.1
Bach, N.J.2
Draheim, S.E.3
Berry, D.R.4
Carlson, D.G.5
Chirgadze, N.Y.6
Clawson, D.K.7
Hartley, L.W.8
Johnson, L.M.9
Jones, N.D.10
McKinney, E.R.11
Mihelich, E.D.12
Olkowski, J.L.13
Schevitz, R.W.14
Smith, A.C.15
Snyder, D.W.16
Sommers, C.D.17
Wery, J.-P.18
-
18
-
-
0000545669
-
Indoles from 2-methylnitrobenzenes by condensation with formamide acetals followed by reduction: 4-benzyloxyindole
-
Batcho, A. D., and Leimgruber, W. Indoles from 2-methylnitrobenzenes by condensation with formamide acetals followed by reduction: 4-benzyloxyindole. Organic Syntheses, 63: 214-225, 1985.
-
(1985)
Organic Syntheses
, vol.63
, pp. 214-225
-
-
Batcho, A.D.1
Leimgruber, W.2
-
19
-
-
85036933577
-
Synthesis of 6- and 7-arylindoles via palladium-catalyzed cross-coupling of 6- and 7-bromoindole with arylboronic acids
-
Carrera, G. M., and Sheppard, G. S. Synthesis of 6- and 7-arylindoles via palladium-catalyzed cross-coupling of 6- and 7-bromoindole with arylboronic acids. Synlett, 93-94, 1994.
-
(1994)
Synlett
, pp. 93-94
-
-
Carrera, G.M.1
Sheppard, G.S.2
-
20
-
-
0028809910
-
Normal p53 status and function despite the development of drug resistance in human breast cancer cells
-
Wosikowski, K., Regis, J. T., Robey, R. W., Alvarez, M., Buters, J. T., Gudas, J. M., and Bates, S. E. Normal p53 status and function despite the development of drug resistance in human breast cancer cells. Cell Growth Differ., 6: 1395-1403, 1995.
-
(1995)
Cell Growth Differ.
, vol.6
, pp. 1395-1403
-
-
Wosikowski, K.1
Regis, J.T.2
Robey, R.W.3
Alvarez, M.4
Buters, J.T.5
Gudas, J.M.6
Bates, S.E.7
-
21
-
-
0027006607
-
Status of the p53 tumor suppressor gene in human squamous carcinoma cell lines
-
Reiss, M., Brash, D. E., Munoz-Antonia, T., Simon, J. A., Ziegler, A., Vellucci, V. F., and Zhou, Z. L. Status of the p53 tumor suppressor gene in human squamous carcinoma cell lines. Oncol. Res., 4: 349-357, 1992. (Pubitemid 23167119)
-
(1992)
Oncology Research
, vol.4
, Issue.8-9
, pp. 349-357
-
-
Reiss, M.1
Brash, D.E.2
Munoz-Antonia, T.3
Simon, J.A.4
Ziegler, A.5
Vellucci, V.F.6
Zhou, Z.-L.7
-
22
-
-
0029846455
-
Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations
-
DOI 10.1002/(SICI)1097-0215(19961115)68:4<501::AID
-
Kawasaki, T., Tomita, Y., Bilim, V., Takeda, M., Takahashi, K., and Kumanishi, T. Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p21/WAF1/CIP1 and/or p53 gene alterations. Int. J. Cancer, 68: 501-505, 1996. (Pubitemid 26414506)
-
(1996)
International Journal of Cancer
, vol.68
, Issue.4
, pp. 501-505
-
-
Kawasaki, T.1
Tomita, Y.2
Bilim, V.3
Takeda, M.4
Takahashi, K.5
Kumanishi, T.6
-
23
-
-
0029913138
-
Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro
-
Elshami, A. A., Saavedra, A., Zhang, H., Kucharczuk, J. C., Spray, D. C., Fishman, G. I., Amin, K. M., Kaiser, L. R., and Albeda, S. M. Gap junctions play a role in the "bystander effect" of the herpes simplex virus thymidine kinase ganciclovir system in vitro. Gene Ther., 3: 85-92, 1996. (Pubitemid 26088496)
-
(1996)
Gene Therapy
, vol.3
, Issue.1
, pp. 85-92
-
-
Elshami, A.A.1
Saavedra, A.2
Zhang, H.3
Kucharczuk, J.C.4
Spray, D.C.5
Fishman, G.I.6
Amin, K.M.7
Kaiser, L.R.8
Albelda, S.M.9
-
24
-
-
0027483695
-
The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman, S. M., Abboud, C. N., Whartenby, K. A., Packman, C. H., Koeplin, D. S., Moolten, F. L., and Abraham, G. N. The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res., 53: 5274-5283, 1993. (Pubitemid 23333399)
-
(1993)
Cancer Research
, vol.53
, Issue.21
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whartenby, K.A.3
Packman, C.H.4
Koeplin, D.S.5
Moolten, F.L.6
Abraham, G.N.7
-
25
-
-
0028108469
-
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: Significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
-
Huber, B. E., Austin, E. A., Richards, C. A., Davis, S. T., and Good, S. S. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc. Natl. Acad. Sci. USA, 91: 8302-8306, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8302-8306
-
-
Huber, B.E.1
Austin, E.A.2
Richards, C.A.3
Davis, S.T.4
Good, S.S.5
-
26
-
-
0030956976
-
The bystander effect of the Nitroreductase/CB 1954 Enzyme/Prodrug system is due to a cell-permeable metabolite
-
Bridgewater, J. A., Knox, R. J., Pitts, J. D., Collins, M. K., and Springer, C. J. The bystander effect of the nitroreductase/CB1954 enzyme/prodrug system is due to a cell-permeable metabolite. Hum. Gene Ther., 8: 709-717, 1997. (Pubitemid 27202057)
-
(1997)
Human Gene Therapy
, vol.8
, Issue.6
, pp. 709-717
-
-
Bridgewater, J.A.1
Knox, R.J.2
Pitts, J.D.3
Collins, M.K.4
Springer, C.J.5
-
27
-
-
0032526178
-
Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine
-
Lawrence, T. S., Rehemtulla, A., Ng, E. Y., Wilson, M., Trosko, J. E., and Stetson, P. L. Preferential cytotoxicity of cells transduced with cytosine deaminase compared to bystander cells after treatment with 5-flucytosine. Cancer Res., 58: 2588-2593, 1998. (Pubitemid 28275430)
-
(1998)
Cancer Research
, vol.58
, Issue.12
, pp. 2588-2593
-
-
Lawrence, T.S.1
Rehemtulla, A.2
Ng, E.Y.3
Wilson, M.4
Trosko, J.E.5
Stetson, P.L.6
-
28
-
-
0035399802
-
Appropriate subcellular localisation of prodrug-activating enzymes has important consequences for suicide gene therapy
-
DOI 10.1002/ijc.1288
-
Spooner, R. A., Maycroft, K. A., Paterson, H., Friedlos, F., Springer, C. J., and Marais, R. Appropriate subcellular localisation of prodrug-activating enzymes important consequences for suicide gene therapy. Int. J. Cancer, 93: 123-130, 2001. (Pubitemid 32539511)
-
(2001)
International Journal of Cancer
, vol.93
, Issue.1
, pp. 123-130
-
-
Spooner, R.A.1
Maycroft, K.A.2
Paterson, H.3
Friedlos, F.4
Springer, C.J.5
Marais, R.6
-
29
-
-
0030968939
-
Targeting gene expression to hypoxic tumor cells
-
Dachs, G. U., Patterson, A. V., Firth, J. D., Ratcliffe, P. J., Townsend, K. M., Stratford, I. J., and Harris, A. L. Targeting gene expression to hypoxic tumor cells. Nat. Med., 3: 515-520, 1997. (Pubitemid 27198648)
-
(1997)
Nature Medicine
, vol.3
, Issue.5
, pp. 515-520
-
-
Dachs, G.U.1
Patterson, A.V.2
Firth, J.D.3
Ratcliffe, P.J.4
Stuart, T.K.M.5
Stratford, I.J.6
Harris, A.L.7
|