메뉴 건너뛰기




Volumn 88, Issue 17, 1996, Pages 1193-1203

Radiosensitizing nucleosides

Author keywords

[No Author keywords available]

Indexed keywords

FLUDARABINE; FLUOROPYRIMIDINE DERIVATIVE; GEMCITABINE; HYDROXYUREA; RADIOSENSITIZING AGENT; THYMIDINE DERIVATIVE;

EID: 0029761745     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/88.17.1193     Document Type: Review
Times cited : (169)

References (107)
  • 1
    • 0029150822 scopus 로고
    • Current status of radiation sensitization by fluoropyrimidines
    • Pu AT, Robertson JM, Lawrence TS. Current status of radiation sensitization by fluoropyrimidines. Oncology 1995;9:707-14.
    • (1995) Oncology , vol.9 , pp. 707-714
    • Pu, A.T.1    Robertson, J.M.2    Lawrence, T.S.3
  • 2
    • 78651054955 scopus 로고
    • The blood supply of neoplasm in the liver
    • Breedis C, Young C. The blood supply of neoplasm in the liver. Am J Pathol 1954;30:969-74.
    • (1954) Am J Pathol , vol.30 , pp. 969-974
    • Breedis, C.1    Young, C.2
  • 3
    • 0018166964 scopus 로고
    • A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2′-deoxyuridine and 5-fluorouracil
    • Ensminger WD, Rosowsky A, Raso V, Levin DC, Glode M, Come S, et al. A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2′-deoxyuridine and 5-fluorouracil. Cancer Res 1978;38(11 Pt 1):3784-92.
    • (1978) Cancer Res , vol.38 , Issue.11 PART 1 , pp. 3784-3792
    • Ensminger, W.D.1    Rosowsky, A.2    Raso, V.3    Levin, D.C.4    Glode, M.5    Come, S.6
  • 4
    • 0344051547 scopus 로고    scopus 로고
    • Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer
    • Meta-Analysis Group In Cancer. Reappraisal of hepatic arterial infusion in the treatment of nonresectable liver metastases from colorectal cancer. J Natl Cancer Inst 1996;88:252-8.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 252-258
  • 7
    • 0024164649 scopus 로고
    • Fluorouracil: Biochemistry and pharmacology
    • Pinedo HM, Peters GF. Fluorouracil: biochemistry and pharmacology. J Clin Oncol 1988;6:1653-64.
    • (1988) J Clin Oncol , vol.6 , pp. 1653-1664
    • Pinedo, H.M.1    Peters, G.F.2
  • 8
    • 0024330933 scopus 로고
    • Effects of 5-fluorouracil on cytotoxicity and RNA metabolism in human colonic carcinoma cells
    • Greenhalgh DA, Parish JH. Effects of 5-fluorouracil on cytotoxicity and RNA metabolism in human colonic carcinoma cells. Cancer Chemother Pharmacol 1989;25:37-44.
    • (1989) Cancer Chemother Pharmacol , vol.25 , pp. 37-44
    • Greenhalgh, D.A.1    Parish, J.H.2
  • 9
    • 0021173119 scopus 로고
    • Lethality associated with incorporation of 5-fluorouracil into preribosomal RNA
    • Herrick D, Kufe DW. Lethality associated with incorporation of 5-fluorouracil into preribosomal RNA. Mol Pharmacol 1984;26:134-40.
    • (1984) Mol Pharmacol , vol.26 , pp. 134-140
    • Herrick, D.1    Kufe, D.W.2
  • 10
    • 0026709880 scopus 로고
    • The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumor cell repopulation
    • McGinn CJ, Kinsella TJ. The experimental and clinical rationale for the use of S-phase-specific radiosensitizers to overcome tumor cell repopulation. Semin Oncol 1992;19:21-8.
    • (1992) Semin Oncol , vol.19 , pp. 21-28
    • McGinn, C.J.1    Kinsella, T.J.2
  • 11
    • 0348049433 scopus 로고
    • Infusional fluoropyrimidines as radiation sensitizers: Clinical implications of laboratory findings
    • Lawrence TS, Maybaum J, Ensminger WD. Infusional fluoropyrimidines as radiation sensitizers: clinical implications of laboratory findings. Infusional Chemotherapy 1994;4:120-3.
    • (1994) Infusional Chemotherapy , vol.4 , pp. 120-123
    • Lawrence, T.S.1    Maybaum, J.2    Ensminger, W.D.3
  • 12
    • 0025651424 scopus 로고
    • Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells
    • Bruso CE, Shewach DS, Lawrence TS. Fluorodeoxyuridine-induced radiosensitization and inhibition of DNA double strand break repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 1990;19:1411-7.
    • (1990) Int J Radiat Oncol Biol Phys , vol.19 , pp. 1411-1417
    • Bruso, C.E.1    Shewach, D.S.2    Lawrence, T.S.3
  • 13
    • 0025986853 scopus 로고
    • The effect of fluorodeoxyuridine on sublethal damage repair in human colon cancer cells
    • Heimburger DK, Shewach DS, Lawrence TS. The effect of fluorodeoxyuridine on sublethal damage repair in human colon cancer cells. Int J Radiat Oncol Biol Phys 1991;21:983-7.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 983-987
    • Heimburger, D.K.1    Shewach, D.S.2    Lawrence, T.S.3
  • 14
    • 0029058456 scopus 로고
    • Dependence of fluorodeoxyuridine-mediated radiosensitization on S phase progression
    • Davis MA, Tang HY, Maybaum J, Lawrence TS. Dependence of fluorodeoxyuridine-mediated radiosensitization on S phase progression. Int J Radiat Biol 1995;67:509-17.
    • (1995) Int J Radiat Biol , vol.67 , pp. 509-517
    • Davis, M.A.1    Tang, H.Y.2    Maybaum, J.3    Lawrence, T.S.4
  • 15
    • 0028245382 scopus 로고
    • Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects
    • Lawrence TS, Davis MA, Maybaum J. Dependence of 5-fluorouracil-mediated radiosensitization on DNA-directed effects. Int J Radiat Oncol Biol Phys 1994;29:519-23.
    • (1994) Int J Radiat Oncol Biol Phys , vol.29 , pp. 519-523
    • Lawrence, T.S.1    Davis, M.A.2    Maybaum, J.3
  • 16
    • 0027497460 scopus 로고
    • Fluoropyrimidines as radiation sensitizers
    • Lawrence TS, Maybaum J. Fluoropyrimidines as radiation sensitizers. Semin Radiat Oncol 1993;3:20-8.
    • (1993) Semin Radiat Oncol , vol.3 , pp. 20-28
    • Lawrence, T.S.1    Maybaum, J.2
  • 17
    • 0020393438 scopus 로고
    • Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays
    • Byfield JE, Calabro-Jones P, Klisak LL, Kulhanian F. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and x rays. Int J Radiat Oncol Biol Phys 1982;8:1923-33.
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1923-1933
    • Byfield, J.E.1    Calabro-Jones, P.2    Klisak, L.L.3    Kulhanian, F.4
  • 18
    • 85053094428 scopus 로고
    • Useful interactions between 5-fluorouracil and radiation in man: 5-fluorouracil as a radiosensitizer
    • Hill BT, Bellamy AS, editors. Boca Raton (FL): CRC Press
    • Byfield JE. Useful interactions between 5-fluorouracil and radiation in man: 5-fluorouracil as a radiosensitizer. In: Hill BT, Bellamy AS, editors. Antitumor drug-radiation interactions. Boca Raton (FL): CRC Press, 1990:87-105.
    • (1990) Antitumor Drug-radiation Interactions , pp. 87-105
    • Byfield, J.E.1
  • 19
    • 0026653689 scopus 로고
    • Radiosensitization by fluorodeoxyuridine: Effects of thymidylate synthase inhibition and cell synchronization
    • Miller EM, Kinsella TJ. Radiosensitization by fluorodeoxyuridine: effects of thymidylate synthase inhibition and cell synchronization. Cancer Res 1992;52:1687-94.
    • (1992) Cancer Res , vol.52 , pp. 1687-1694
    • Miller, E.M.1    Kinsella, T.J.2
  • 20
    • 0028019863 scopus 로고
    • The role of cell cycle redistribution in radiosensitization: Implications regarding the mechanism of fluorodeoxyuridine radiosensitization
    • McGinn CJ, Miller EM, Lindstrom MJ, Kunugi KA, Johnston PG, Kinsella TJ. The role of cell cycle redistribution in radiosensitization: implications regarding the mechanism of fluorodeoxyuridine radiosensitization. Int J Radiat Oncol Biol Phys 1994;30:851-9.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 851-859
    • McGinn, C.J.1    Miller, E.M.2    Lindstrom, M.J.3    Kunugi, K.A.4    Johnston, P.G.5    Kinsella, T.J.6
  • 21
    • 0014264750 scopus 로고
    • Cyclic x-ray responses in mammalian cells in vitro
    • Sinclair WK. Cyclic x-ray responses in mammalian cells in vitro. Radiat Res 1968;33:620-43.
    • (1968) Radiat Res , vol.33 , pp. 620-643
    • Sinclair, W.K.1
  • 22
    • 0002309215 scopus 로고
    • Variations in several responses of HeLa cells to X-irradiation during the division cycle
    • Terasima T, Tolmach LJ. Variations in several responses of HeLa cells to X-irradiation during the division cycle. Biophys J 1963;3:11-33.
    • (1963) Biophys J , vol.3 , pp. 11-33
    • Terasima, T.1    Tolmach, L.J.2
  • 23
    • 85035171945 scopus 로고    scopus 로고
    • Fluorodeoxyuridine-mediated cytotoxicity and radiosensitization require S-phase progression
    • In press
    • Lawrence TS, Davis MA, Tang HY, Maybaum J. Fluorodeoxyuridine-mediated cytotoxicity and radiosensitization require S-phase progression. Int J Radiat Biol. In press.
    • Int J Radiat Biol.
    • Lawrence, T.S.1    Davis, M.A.2    Tang, H.Y.3    Maybaum, J.4
  • 24
    • 0029987652 scopus 로고    scopus 로고
    • Fluoropyrimidine-mediated radiosensitization depends on cyclin E-dependent kinase activation
    • Lawrence TS, Davis MA, Looney TL. Fluoropyrimidine-mediated radiosensitization depends on cyclin E-dependent kinase activation. Cancer Res 1996;56:2303-6.
    • (1996) Cancer Res , vol.56 , pp. 2303-2306
    • Lawrence, T.S.1    Davis, M.A.2    Looney, T.L.3
  • 25
    • 0027500246 scopus 로고
    • Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents
    • published erratum appears in Oncogene 1993;8:2605.
    • Fritsche M, Haessler C, Brandner G. Induction of nuclear accumulation of the tumor-suppressor protein p53 by DNA-damaging agents [published erratum appears in Oncogene 1993;8:2605]. Oncogene 1993;8:307-18.
    • (1993) Oncogene , vol.8 , pp. 307-318
    • Fritsche, M.1    Haessler, C.2    Brandner, G.3
  • 26
    • 0027212267 scopus 로고
    • Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents
    • Tishler RB, Calderwood SK, Coleman CN, Price BD. Increases in sequence specific DNA binding by p53 following treatment with chemotherapeutic and DNA damaging agents. Cancer Res 1993;53(10 Suppl): 2212-6.
    • (1993) Cancer Res , vol.53 , Issue.10 SUPPL. , pp. 2212-2216
    • Tishler, R.B.1    Calderwood, S.K.2    Coleman, C.N.3    Price, B.D.4
  • 28
    • 0027893001 scopus 로고
    • Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage
    • Slichenmyer WJ, Nelson WG, Slebos RJ, Kastan MB. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. Cancer Res 1993;53:4164-8.
    • (1993) Cancer Res , vol.53 , pp. 4164-4168
    • Slichenmyer, W.J.1    Nelson, W.G.2    Slebos, R.J.3    Kastan, M.B.4
  • 29
    • 0027176479 scopus 로고
    • p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
    • see comment citations in Medline
    • Brachman DG, Becken M, Graves D, Haraf D, Vokes E, Weichselbaum RR. p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines [see comment citations in Medline]. Cancer Res 1993;53:3667-9.
    • (1993) Cancer Res , vol.53 , pp. 3667-3669
    • Brachman, D.G.1    Becken, M.2    Graves, D.3    Haraf, D.4    Vokes, E.5    Weichselbaum, R.R.6
  • 30
    • 0026488680 scopus 로고
    • Mutations in the p53 gene in radiationsensitive and -resistant human squamous carcinoma cells
    • Jung M, Notario V, Dritschilo A. Mutations in the p53 gene in radiationsensitive and -resistant human squamous carcinoma cells. Cancer Res 1992;52:6390-3.
    • (1992) Cancer Res , vol.52 , pp. 6390-6393
    • Jung, M.1    Notario, V.2    Dritschilo, A.3
  • 32
    • 0028859453 scopus 로고
    • p53 status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: A novel hypothesis based on clinical findings
    • Jansson T, Inganas M, Sjogren S, Norberg T, Lindgren A, Holmberg L, et al. p53 status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: a novel hypothesis based on clinical findings. J Clin Oncol 1995;13:2745-51.
    • (1995) J Clin Oncol , vol.13 , pp. 2745-2751
    • Jansson, T.1    Inganas, M.2    Sjogren, S.3    Norberg, T.4    Lindgren, A.5    Holmberg, L.6
  • 33
    • 0028019247 scopus 로고
    • Treatment of locally advanced cancer of the head and neck with 5′-iododeoxyuridine and hyperfractionated radiation therapy: Measurement of cell labeling and thymidine replacement
    • Epstein AH, Lebovics RS, Goffman T, Teague D, Fuetsch ES, Glatstein E, et al. Treatment of locally advanced cancer of the head and neck with 5′-iododeoxyuridine and hyperfractionated radiation therapy: measurement of cell labeling and thymidine replacement. J Natl Cancer Inst 1994; 86:1775-80.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1775-1780
    • Epstein, A.H.1    Lebovics, R.S.2    Goffman, T.3    Teague, D.4    Fuetsch, E.S.5    Glatstein, E.6
  • 34
    • 0028911680 scopus 로고
    • Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine and vincristine for the treatment of anaplastic gliomas
    • Levin VA, Prados MD, Wara WM, Davis RL, Gutin PH, Phillips TL, et al. Radiation therapy and bromodeoxyuridine chemotherapy followed by procarbazine, lomustine and vincristine for the treatment of anaplastic gliomas. Int J Radiat Oncol Biol Phys 1995;32:75-83.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 75-83
    • Levin, V.A.1    Prados, M.D.2    Wara, W.M.3    Davis, R.L.4    Gutin, P.H.5    Phillips, T.L.6
  • 35
    • 0023767406 scopus 로고
    • Intra-arterial bromodeoxyuridine radiosensitization and radiation in treatment of malignant astrocytomas
    • Greenberg HS, Chandler WF, Diaz RF, Ensminger WD, Junck L, Page MA, et al. Intra-arterial bromodeoxyuridine radiosensitization and radiation in treatment of malignant astrocytomas. J Neurosurg 1988;69:500-5.
    • (1988) J Neurosurg , vol.69 , pp. 500-505
    • Greenberg, H.S.1    Chandler, W.F.2    Diaz, R.F.3    Ensminger, W.D.4    Junck, L.5    Page, M.A.6
  • 36
    • 0028021915 scopus 로고
    • National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: Results in anaplastic astrocytoma
    • Sullivan FJ, Herscher LL, Cook JA, Smith J, Steinberg SM, Epstein AH, et al. National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma. Int J Radiat Oncol Biol Phys 1994;30:583-90.
    • (1994) Int J Radiat Oncol Biol Phys , vol.30 , pp. 583-590
    • Sullivan, F.J.1    Herscher, L.L.2    Cook, J.A.3    Smith, J.4    Steinberg, S.M.5    Epstein, A.H.6
  • 37
    • 0025942266 scopus 로고
    • Evaluation of bromodeoxyuridine in glioblastoma multiforme: A Northern California Cancer Center Phase II study
    • see comment citations in Medline
    • Phillips TL, Levin VA, Ahn DK, Gutin PH, Davis RL, Wilson CB, et al. Evaluation of bromodeoxyuridine in glioblastoma multiforme: a Northern California Cancer Center Phase II study [see comment citations in Medline]. Int J Radiat Oncol Biol Phys 1991;21:709-14.
    • (1991) Int J Radiat Oncol Biol Phys , vol.21 , pp. 709-714
    • Phillips, T.L.1    Levin, V.A.2    Ahn, D.K.3    Gutin, P.H.4    Davis, R.L.5    Wilson, C.B.6
  • 38
    • 0029114147 scopus 로고
    • Results of a randomized comparison of radiotherapy and bromodeoxyuridine with radiotherapy alone for brain metastases: Report of RTOG trial 89-05
    • Phillips TL, Scott CB, Leibel SA, Rotman M, Weigensberg IJ. Results of a randomized comparison of radiotherapy and bromodeoxyuridine with radiotherapy alone for brain metastases: report of RTOG trial 89-05. Int J Radiat Oncol Biol Phys 1995;33:339-48.
    • (1995) Int J Radiat Oncol Biol Phys , vol.33 , pp. 339-348
    • Phillips, T.L.1    Scott, C.B.2    Leibel, S.A.3    Rotman, M.4    Weigensberg, I.J.5
  • 39
    • 0025979284 scopus 로고
    • Primary treatment of large and massive adult sarcomas with iododeoxyuridine and aggressive hyperfractionated irradiation
    • Goffman T, Tochner Z, Glatstein E. Primary treatment of large and massive adult sarcomas with iododeoxyuridine and aggressive hyperfractionated irradiation. Cancer 1991;67:572-6.
    • (1991) Cancer , vol.67 , pp. 572-576
    • Goffman, T.1    Tochner, Z.2    Glatstein, E.3
  • 41
    • 0024541879 scopus 로고
    • A phase I study of intraarterial iododeoxyuridine in patients with colorectal liver metastases
    • Chang AE, Collins JM, Speth PA, Smith R, Rowland JB, Walton L, et al. A phase I study of intraarterial iododeoxyuridine in patients with colorectal liver metastases. J Clin Oncol 1989;7:662-8.
    • (1989) J Clin Oncol , vol.7 , pp. 662-668
    • Chang, A.E.1    Collins, J.M.2    Speth, P.A.3    Smith, R.4    Rowland, J.B.5    Walton, L.6
  • 42
    • 0010638865 scopus 로고
    • A phase I/II study of bromodeoxyuridine (BrdU) and radiation therapy (RT) for locally advanced cervix cancer
    • Robertson JR, Johnston CM, Eisbruch A, Reynolds K, Roberts J, Lawrence TS. A phase I/II study of bromodeoxyuridine (BrdU) and radiation therapy (RT) for locally advanced cervix cancer. Proc ASCO 1995; 14:201.
    • (1995) Proc ASCO , vol.14 , pp. 201
    • Robertson, J.R.1    Johnston, C.M.2    Eisbruch, A.3    Reynolds, K.4    Roberts, J.5    Lawrence, T.S.6
  • 43
    • 0025239917 scopus 로고
    • Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report
    • Levin VA, Silver P, Hannigan J, Wara WM, Gutin PH, Davis RL, et al. Superiority of post-radiotherapy adjuvant chemotherapy with CCNU, procarbazine, and vincristine (PCV) over BCNU for anaplastic gliomas: NCOG 6G61 final report. Int J Radiat Oncol Biol Phys 1990;18:321-4.
    • (1990) Int J Radiat Oncol Biol Phys , vol.18 , pp. 321-324
    • Levin, V.A.1    Silver, P.2    Hannigan, J.3    Wara, W.M.4    Gutin, P.H.5    Davis, R.L.6
  • 44
    • 0014639058 scopus 로고
    • Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. II. Pulse-and steady state radiolysis of bromouracil-substituted and unsubstituted DNA
    • Zimbrick JD, Ward JF, Myers LS Jr. Studies on the chemical basis of cellular radiosensitization by 5-bromouracil substitution in DNA. II. Pulse-and steady state radiolysis of bromouracil-substituted and unsubstituted DNA. Int J Radial Biol Relat Stud Phys Chem Med 1969;16:525-34.
    • (1969) Int J Radial Biol Relat Stud Phys Chem Med , vol.16 , pp. 525-534
    • Zimbrick, J.D.1    Ward, J.F.2    Myers Jr., L.S.3
  • 45
    • 0026593802 scopus 로고
    • Decrease in TTP pools mediated by 5-bromo-2′-deoxyuridine exposure in a human glioblastoma cell line
    • Shewach DS, Ellero J, Mancini WR, Ensminger WD. Decrease in TTP pools mediated by 5-bromo-2′-deoxyuridine exposure in a human glioblastoma cell line. Biochem Pharmacol 1992;43:1579-85.
    • (1992) Biochem Pharmacol , vol.43 , pp. 1579-1585
    • Shewach, D.S.1    Ellero, J.2    Mancini, W.R.3    Ensminger, W.D.4
  • 46
    • 0019829553 scopus 로고
    • Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance
    • Ashman CR, Davidson RL. Bromodeoxyuridine mutagenesis in mammalian cells is related to deoxyribonucleotide pool imbalance. Mol Cell Biol 1981;1:254-60.
    • (1981) Mol Cell Biol , vol.1 , pp. 254-260
    • Ashman, C.R.1    Davidson, R.L.2
  • 47
    • 0025058784 scopus 로고
    • Radiosensitization of Chinese hamster V79 cells by bromodeoxyuridine substitution of thymidine: Enhancement of radiation-induced toxicity and DNA strand break production by monofilar and bifilar substitution
    • Ling LL, Ward JF. Radiosensitization of Chinese hamster V79 cells by bromodeoxyuridine substitution of thymidine: enhancement of radiation-induced toxicity and DNA strand break production by monofilar and bifilar substitution. Radiat Res 1990;121:76-83.
    • (1990) Radiat Res , vol.121 , pp. 76-83
    • Ling, L.L.1    Ward, J.F.2
  • 48
    • 0026633463 scopus 로고
    • Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine
    • Miller EM, Fowler JF, Kinsella TJ. Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. I. Radiosensitization of human colon cancer cells by iododeoxyuridine. Radiat Res 1992;131:81-9.
    • (1992) Radiat Res , vol.131 , pp. 81-89
    • Miller, E.M.1    Fowler, J.F.2    Kinsella, T.J.3
  • 49
    • 0026647385 scopus 로고
    • Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. II. Radiosensitization of human colon cancer cells by bromodeoxyuridine
    • Miller EM, Fowler JF, Kinsella TJ. Linear-quadratic analysis of radiosensitization by halogenated pyrimidines. II. Radiosensitization of human colon cancer cells by bromodeoxyuridine. Radiat Res 1992;131:90-7.
    • (1992) Radiat Res , vol.131 , pp. 90-97
    • Miller, E.M.1    Fowler, J.F.2    Kinsella, T.J.3
  • 50
    • 0025742796 scopus 로고
    • Mechanism of radiosensitization by halogenated pyrimidines: Bromodeoxyuridine and alpha-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells
    • Iliakis G, Kurtzman S. Mechanism of radiosensitization by halogenated pyrimidines: bromodeoxyuridine and alpha-arabinofuranosyladenine affect similar subsets of radiation-induced potentially lethal lesions in plateau-phase Chinese hamster ovary cells. Radiat Res 1991;127:45-51.
    • (1991) Radiat Res , vol.127 , pp. 45-51
    • Iliakis, G.1    Kurtzman, S.2
  • 51
    • 0024371774 scopus 로고
    • Mechanism of radiosensitization by halogenated pyrimidines: Effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing
    • Iliakis G, Kurtzman S, Pantelias G, Okayasu R. Mechanism of radiosensitization by halogenated pyrimidines: effect of BrdU on radiation induction of DNA and chromosome damage and its correlation with cell killing, Radiat Res 1989;119:286-304.
    • (1989) Radiat Res , vol.119 , pp. 286-304
    • Iliakis, G.1    Kurtzman, S.2    Pantelias, G.3    Okayasu, R.4
  • 52
    • 0028821922 scopus 로고
    • Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed-field gel electrophoresis
    • Lawrence TS, Davis MA, Normolle DP. Effect of bromodeoxyuridine on radiation-induced DNA damage and repair based on DNA fragment size using pulsed-field gel electrophoresis. Radiat Res 1995;144:282-7.
    • (1995) Radiat Res , vol.144 , pp. 282-287
    • Lawrence, T.S.1    Davis, M.A.2    Normolle, D.P.3
  • 54
    • 0025128324 scopus 로고
    • The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells
    • Lawrence TS, Davis MA, Maybaum J, Stetson PL, Ensminger WD. The effect of single versus double-strand substitution on halogenated pyrimidine-induced radiosensitization and DNA strand breakage in human tumor cells. Radiat Res 1990;123:192-8.
    • (1990) Radiat Res , vol.123 , pp. 192-198
    • Lawrence, T.S.1    Davis, M.A.2    Maybaum, J.3    Stetson, P.L.4    Ensminger, W.D.5
  • 56
    • 0029163013 scopus 로고
    • Incorporation of 5-bromo-2′-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion
    • Knol JA, Walker SC, Robertson JM, Yang Z, DeRemer S, Stetson PL. et al. Incorporation of 5-bromo-2′-deoxyuridine into colorectal liver metastases and liver in patients receiving a 7-day hepatic arterial infusion. Cancer Res 1995;55:3687-91.
    • (1995) Cancer Res , vol.55 , pp. 3687-3691
    • Knol, J.A.1    Walker, S.C.2    Robertson, J.M.3    Yang, Z.4    Deremer, S.5    Stetson, P.L.6
  • 57
    • 0026508766 scopus 로고
    • Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine
    • Cook JA, Glass J, Lebovics R, Bobo H, Pass H, DeLaney TF, et al. Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine. Cancer Res 1992;52:719-25.
    • (1992) Cancer Res , vol.52 , pp. 719-725
    • Cook, J.A.1    Glass, J.2    Lebovics, R.3    Bobo, H.4    Pass, H.5    Delaney, T.F.6
  • 59
    • 0023767241 scopus 로고
    • Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells
    • Ackland SP, Schilsky RL, Beckett MA, Weichselbaum RR. Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells. Cancer Res 1988;48:4244-9.
    • (1988) Cancer Res , vol.48 , pp. 4244-4249
    • Ackland, S.P.1    Schilsky, R.L.2    Beckett, M.A.3    Weichselbaum, R.R.4
  • 60
    • 0028301189 scopus 로고
    • Iododeoxyuridine chemosensitization of cis-diamminedichloroplatinum(II) in human bladder cancer cells
    • Chi KH, Kunugi KA, Kinsella TJ. Iododeoxyuridine chemosensitization of cis-diamminedichloroplatinum(II) in human bladder cancer cells. Cancer Res 1994;54:2701-6.
    • (1994) Cancer Res , vol.54 , pp. 2701-2706
    • Chi, K.H.1    Kunugi, K.A.2    Kinsella, T.J.3
  • 61
    • 0029087491 scopus 로고
    • Adjuvant chemotherapy for soft-tissue sarcoma: Review and meta-analysis of the published results of randomised clinical trials
    • Tierney JF, Mosseri V, Stewart LA, Souhami RL, Parmar MK. Adjuvant chemotherapy for soft-tissue sarcoma: review and meta-analysis of the published results of randomised clinical trials. Br J Cancer 1995;72:469-75.
    • (1995) Br J Cancer , vol.72 , pp. 469-475
    • Tierney, J.F.1    Mosseri, V.2    Stewart, L.A.3    Souhami, R.L.4    Parmar, M.K.5
  • 62
    • 0028284681 scopus 로고
    • Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo
    • Lawrence TS, Davis MA, Stetson PL, Maybaum J, Ensminger WD. Kinetics of bromodeoxyuridine elimination from human colon cancer cells in vitro and in vivo. Cancer Res 1994;54:2964-8.
    • (1994) Cancer Res , vol.54 , pp. 2964-2968
    • Lawrence, T.S.1    Davis, M.A.2    Stetson, P.L.3    Maybaum, J.4    Ensminger, W.D.5
  • 64
    • 0026778383 scopus 로고
    • Mechanism of action of hydroxyurea
    • Yarbro JW. Mechanism of action of hydroxyurea. Semin Oncol 1992; 19(3 Suppl 9):1-10.
    • (1992) Semin Oncol , vol.193 , Issue.9 SUPPL. , pp. 1-10
    • Yarbro, J.W.1
  • 65
    • 0026755811 scopus 로고
    • An overview of the clinical experience with hydroxyurea
    • Donehower RC. An overview of the clinical experience with hydroxyurea. Semin Oncol 1992;19(3 Suppl 9):11-9.
    • (1992) Semin Oncol , vol.19 , Issue.3 SUPPL. 9 , pp. 11-19
    • Donehower, R.C.1
  • 66
    • 0017764766 scopus 로고
    • Concomitant hydroxyurea and irradiation. Clinical experience with 100 patients with advanced head and neck cancer at Pennsylvania hospital
    • Lerner HJ. Concomitant hydroxyurea and irradiation. Clinical experience with 100 patients with advanced head and neck cancer at Pennsylvania hospital. Am J Surg 1977;134:505-9.
    • (1977) Am J Surg , vol.134 , pp. 505-509
    • Lerner, H.J.1
  • 67
    • 0017761499 scopus 로고
    • Hydroxyurea as a radiation sensitizer in women with carcinoma of the uterine cervix
    • Piver MS, Barlow JJ, Vongtama V, Blumenson L. Hydroxyurea as a radiation sensitizer in women with carcinoma of the uterine cervix. Am J Obstet Gynecol 1977;129:379-83.
    • (1977) Am J Obstet Gynecol , vol.129 , pp. 379-383
    • Piver, M.S.1    Barlow, J.J.2    Vongtama, V.3    Blumenson, L.4
  • 68
    • 0029039072 scopus 로고
    • Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer
    • Vokes EE, Stupp R, Haraf D, Moran W, Malone D, Wenig B, et al. Hydroxyurea with continuous infusion paclitaxel, 5-fluorouracil, and concomitant radiotherapy for poor-prognosis head and neck cancer. Semin Oncol 1995;22:47-52.
    • (1995) Semin Oncol , vol.22 , pp. 47-52
    • Vokes, E.E.1    Stupp, R.2    Haraf, D.3    Moran, W.4    Malone, D.5    Wenig, B.6
  • 69
    • 0023234589 scopus 로고
    • Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer
    • Piver MS, Vongtama V, Emrich LJ. Hydroxyurea plus pelvic radiation versus placebo plus pelvic radiation in surgically staged stage IIIB cervical cancer. J Surg Oncol 1987;35:129-34.
    • (1987) J Surg Oncol , vol.35 , pp. 129-134
    • Piver, M.S.1    Vongtama, V.2    Emrich, L.J.3
  • 70
    • 0024376548 scopus 로고
    • Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer
    • Piver MS, Khalil M, Emrich LJ. Hydroxyurea plus pelvic irradiation versus placebo plus pelvic irradiation in nonsurgically staged stage IIIB cervical cancer. J Surg Oncol 1989;42:120-5.
    • (1989) J Surg Oncol , vol.42 , pp. 120-125
    • Piver, M.S.1    Khalil, M.2    Emrich, L.J.3
  • 71
    • 0027165660 scopus 로고
    • Hydroxyurea versus misonidazole with radiation in cervical carcinoma: Long-term follow-up of a Gynecologic Oncology Group trial
    • Stehman FB, Bundy BN, Thomas G, Keys HM, d'Ablaing G 3d, Fowlder WC Jr, et al. Hydroxyurea versus misonidazole with radiation in cervical carcinoma: long-term follow-up of a Gynecologic Oncology Group trial. J Clin Oncol 1993;11:1523-8.
    • (1993) J Clin Oncol , vol.11 , pp. 1523-1528
    • Stehman, F.B.1    Bundy, B.N.2    Thomas, G.3    Keys, H.M.4    D'Ablaing III, G.5    Fowlder Jr., W.C.6
  • 72
    • 0019441168 scopus 로고
    • Hydroxyurea revisited: A decade of clinical effects studies
    • Sinclair WK. Hydroxyurea revisited: a decade of clinical effects studies. Int J Radiat Oncol Biol Phys 1981;7:631-7.
    • (1981) Int J Radiat Oncol Biol Phys , vol.7 , pp. 631-637
    • Sinclair, W.K.1
  • 73
    • 0009476179 scopus 로고
    • Enhancement of radiosensitivity by pre-irradiation and post-irradiation exposure to hydroxyurea in a human cervical carcinoma cell line, Caski
    • Kuo ML, Kinsella TJ. Enhancement of radiosensitivity by pre-irradiation and post-irradiation exposure to hydroxyurea in a human cervical carcinoma cell line, Caski. Proc Am Assoc Cancer Res 1994;35:A3685.
    • (1994) Proc Am Assoc Cancer Res , vol.35
    • Kuo, M.L.1    Kinsella, T.J.2
  • 74
    • 0029025552 scopus 로고
    • The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells
    • Kuo ML, Kunugi KA, Lindstrom MJ, Kinsella TJ. The interaction of hydroxyurea and iododeoxyuridine on the radiosensitivity of human bladder cancer cells. Cancer Res 1995;55:2800-5.
    • (1995) Cancer Res , vol.55 , pp. 2800-2805
    • Kuo, M.L.1    Kunugi, K.A.2    Lindstrom, M.J.3    Kinsella, T.J.4
  • 75
    • 0026475008 scopus 로고
    • EPR stopped-flow studies of the reaction of the tyrosyl radical of protein R2 from ribonucleotide reductase with hydroxyurea
    • Lassmann G, Thelander L, Graslund A. EPR stopped-flow studies of the reaction of the tyrosyl radical of protein R2 from ribonucleotide reductase with hydroxyurea. Biochem Biophys Res Commun 1992;188:879-87.
    • (1992) Biochem Biophys Res Commun , vol.188 , pp. 879-887
    • Lassmann, G.1    Thelander, L.2    Graslund, A.3
  • 76
    • 0027605113 scopus 로고
    • DNA damage and cell cycle regulation of ribonucleotide reductase
    • Elledge SJ, Zhou Z, Allen JB, Navas TA. DNA damage and cell cycle regulation of ribonucleotide reductase. Bioessays 1993;15:333-9.
    • (1993) Bioessays , vol.15 , pp. 333-339
    • Elledge, S.J.1    Zhou, Z.2    Allen, J.B.3    Navas, T.A.4
  • 77
    • 0025296739 scopus 로고
    • Allosteric interaction of components of the replitase complex is responsible for enzyme cross-inhibition
    • Plucinski TM, Fager RS, Reddy GP. Allosteric interaction of components of the replitase complex is responsible for enzyme cross-inhibition. Mol Pharmacol 1990;38:114-20.
    • (1990) Mol Pharmacol , vol.38 , pp. 114-120
    • Plucinski, T.M.1    Fager, R.S.2    Reddy, G.P.3
  • 78
    • 0025214461 scopus 로고
    • Ribonucleotide reductases: Amazing and confusing
    • Stubbe J. Ribonucleotide reductases: amazing and confusing. J Biol Chem 1990;265:5329-32.
    • (1990) J Biol Chem , vol.265 , pp. 5329-5332
    • Stubbe, J.1
  • 79
    • 0019948137 scopus 로고
    • Therapeutic response of leukemic mice treated with fluorinated pyrimidines and inhibitors of deoxyuridylate synthesis
    • Moran RG, Danenberg PV, Heidelberger C. Therapeutic response of leukemic mice treated with fluorinated pyrimidines and inhibitors of deoxyuridylate synthesis. Biochem Pharmacol 1982;31:2929-35.
    • (1982) Biochem Pharmacol , vol.31 , pp. 2929-2935
    • Moran, R.G.1    Danenberg, P.V.2    Heidelberger, C.3
  • 80
    • 0028022127 scopus 로고
    • Gemcitabine: Current status of phase I and II trials
    • Kaye SB. Gemcitabine: current status of phase I and II trials. J Clin Oncol 1994;12:1527-31.
    • (1994) J Clin Oncol , vol.12 , pp. 1527-1531
    • Kaye, S.B.1
  • 81
    • 0000635437 scopus 로고
    • A randomized trial of gemcitabine (GEM) versus 5FU as first-line therapy in advanced pancreatic cancer
    • Moore M, Andersen J, Burris H, Tarassoff P, Green M, Casper E, et al. A randomized trial of gemcitabine (GEM) versus 5FU as first-line therapy in advanced pancreatic cancer. Proc ASCO 1995;14:A473.
    • (1995) Proc ASCO , vol.14
    • Moore, M.1    Andersen, J.2    Burris, H.3    Tarassoff, P.4    Green, M.5    Casper, E.6
  • 82
    • 0028033227 scopus 로고
    • Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: A phase II study
    • Anderson H, Lund B, Bach F, Thatcher N, Walling J, Hansen HH. Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 1994;12:1821-6.
    • (1994) J Clin Oncol , vol.12 , pp. 1821-1826
    • Anderson, H.1    Lund, B.2    Bach, F.3    Thatcher, N.4    Walling, J.5    Hansen, H.H.6
  • 83
    • 0027993707 scopus 로고
    • Efficacy and safety profile of gemcitabine in non-small-cell lung cancer: A phase II study
    • Abratt RP, Bezwoda WR, Falkson G, Goedhals L, Hacking D, Rugg TA. Efficacy and safety profile of gemcitabine in non-small-cell lung cancer: a phase II study. J Clin Oncol 1994;12:1535-40.
    • (1994) J Clin Oncol , vol.12 , pp. 1535-1540
    • Abratt, R.P.1    Bezwoda, W.R.2    Falkson, G.3    Goedhals, L.4    Hacking, D.5    Rugg, T.A.6
  • 84
    • 0028241688 scopus 로고
    • A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group
    • Catimel G, Vermerken JB, Clavel M, de Mulder P, Judson I, Sessa C, et al. A phase II study of Gemcitabine (LY 188011) in patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol 1994;5:543-7.
    • (1994) Ann Oncol , vol.5 , pp. 543-547
    • Catimel, G.1    Vermerken, J.B.2    Clavel, M.3    De Mulder, P.4    Judson, I.5    Sessa, C.6
  • 85
    • 0005894287 scopus 로고
    • Difluorodeoxycytidine (GEMCITABINE): A phase II study in patients with advanced breast cancer
    • Carmichael J, Possinger K, Philip P, Beykirch M, Kerr H, Walling J, et al. Difluorodeoxycytidine (GEMCITABINE): a phase II study in patients with advanced breast cancer. Proc ASCO 1993;12:A57.
    • (1993) Proc ASCO , vol.12
    • Carmichael, J.1    Possinger, K.2    Philip, P.3    Beykirch, M.4    Kerr, H.5    Walling, J.6
  • 86
    • 0023783698 scopus 로고
    • Comparision of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine
    • Heinemann V, Hertel LW, Grindey GB, Plunkett W. Comparision of the cellular pharmacokinetics and toxicity of 2′,2′-difluorodeoxycytidine and 1-β-D-arabinofuranosylcytosine. Cancer Res 1988;48:4024-31.
    • (1988) Cancer Res , vol.48 , pp. 4024-4031
    • Heinemann, V.1    Hertel, L.W.2    Grindey, G.B.3    Plunkett, W.4
  • 87
    • 0027085703 scopus 로고
    • Nucleotide specificity of human deoxycytidine kinase
    • Shewach DS, Reynolds KK, Hertel L. Nucleotide specificity of human deoxycytidine kinase. Mol Pharmacol 1992;42:518-24.
    • (1992) Mol Pharmacol , vol.42 , pp. 518-524
    • Shewach, D.S.1    Reynolds, K.K.2    Hertel, L.3
  • 89
    • 0029060757 scopus 로고
    • Fludarabine- and gemcitabine-induced apoptosis: Incorporation of analogs into DNA is a critical event
    • Huang P, Plunkett W. Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event. Cancer Chemother Pharmacol 1995;36:181-8.
    • (1995) Cancer Chemother Pharmacol , vol.36 , pp. 181-188
    • Huang, P.1    Plunkett, W.2
  • 90
    • 0025049372 scopus 로고
    • Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine
    • Heinemann V, Xu YZ, Chubb S, Sen A, Hertel LW, Grindey GB, et al. Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2′,2′-difluorodeoxycytidine. Mol Pharmacol 1990;38:567-72.
    • (1990) Mol Pharmacol , vol.38 , pp. 567-572
    • Heinemann, V.1    Xu, Y.Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6
  • 91
    • 0027429568 scopus 로고
    • Effect of a template-located 2′,2′-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3′→5′exonuclease-) fragment
    • Schy WE, Hertel LW, Kroin JS, Bloom LB, Goodman MF, Richardson FC. Effect of a template-located 2′,2′-difluorodeoxycytidine on the kinetics and fidelity of base insertion by Klenow (3′→5′exonuclease-) fragment. Cancer Res 1993;53:4582-7.
    • (1993) Cancer Res , vol.53 , pp. 4582-4587
    • Schy, W.E.1    Hertel, L.W.2    Kroin, J.S.3    Bloom, L.B.4    Goodman, M.F.5    Richardson, F.C.6
  • 92
    • 0026571795 scopus 로고
    • Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation
    • Heinemann V, Xu YZ, Chubb S, Sen A, Hertel LW, Grindey GB, et al. Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: a mechanism of self-potentiation. Cancer Res 1992;52:533-9.
    • (1992) Cancer Res , vol.52 , pp. 533-539
    • Heinemann, V.1    Xu, Y.Z.2    Chubb, S.3    Sen, A.4    Hertel, L.W.5    Grindey, G.B.6
  • 93
    • 0026984625 scopus 로고
    • Effect of 2′,2′-difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro
    • Rockwell S, Grindey GB. Effect of 2′,2′-difluorodeoxycytidine on the viability and radiosensitivity of EMT6 cells in vitro. Oncol Res 1992;4: 151-5.
    • (1992) Oncol Res , vol.4 , pp. 151-155
    • Rockwell, S.1    Grindey, G.B.2
  • 94
    • 0028240063 scopus 로고
    • Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells
    • Shewach DS, Hahn TM, Chang E, Hertel LW, Lawrence TS. Metabolism of 2′,2′-difluoro-2′-deoxycytidine and radiation sensitization of human colon carcinoma cells. Cancer Res 1994;54:3218-23.
    • (1994) Cancer Res , vol.54 , pp. 3218-3223
    • Shewach, D.S.1    Hahn, T.M.2    Chang, E.3    Hertel, L.W.4    Lawrence, T.S.5
  • 96
    • 0024371477 scopus 로고
    • Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: Comparison with fixation of PLD
    • Iliakis G, Pantelias G, Okayasu R, Seaner R. Comparative studies on repair inhibition by araA, araC and aphidicolin of radiation induced DNA and chromosome damage in rodent cells: comparison with fixation of PLD. Int J Radiat Oncol Biol Phys 1989;16:1261-5.
    • (1989) Int J Radiat Oncol Biol Phys , vol.16 , pp. 1261-1265
    • Iliakis, G.1    Pantelias, G.2    Okayasu, R.3    Seaner, R.4
  • 98
    • 0027436016 scopus 로고
    • Fludarabine: Pharmacokinetics, mechanisms of action, and rationales for combination therapies
    • Plunkett W, Gandhi V, Huang P, Robertson LE, Yang LY, Gregoire V, et al. Fludarabine: pharmacokinetics, mechanisms of action, and rationales for combination therapies. Semin Oncol 1993;20(5 Suppl 7):2-12.
    • (1993) Semin Oncol , vol.20 , Issue.5 SUPPL. 7 , pp. 2-12
    • Plunkett, W.1    Gandhi, V.2    Huang, P.3    Robertson, L.E.4    Yang, L.Y.5    Gregoire, V.6
  • 99
    • 0024495782 scopus 로고
    • Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides
    • Huang P, Siciliano MJ, Plunkett W. Gene deletion, a mechanism of induced mutation by arabinosyl nucleosides. Mutat Res 1989;210:291-301.
    • (1989) Mutat Res , vol.210 , pp. 291-301
    • Huang, P.1    Siciliano, M.J.2    Plunkett, W.3
  • 100
    • 0022498513 scopus 로고
    • The potentiation of radiation response on murine tumor by fludarabine phosphate
    • Kim JH, Alfieri AA, Kim SH, Fuks Z. The potentiation of radiation response on murine tumor by fludarabine phosphate. Cancer Lett 1986; 31:69-76.
    • (1986) Cancer Lett , vol.31 , pp. 69-76
    • Kim, J.H.1    Alfieri, A.A.2    Kim, S.H.3    Fuks, Z.4
  • 102
    • 0028032726 scopus 로고
    • The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumor radiation response in vivo
    • Gregoire V, Van NT, Stephens LC, Brock WA, Milas L, Plunkett W, et al. The role of fludarabine-induced apoptosis and cell cycle synchronization in enhanced murine tumor radiation response in vivo. Cancer Res 1994;54:6201-9.
    • (1994) Cancer Res , vol.54 , pp. 6201-6209
    • Gregoire, V.1    Van, N.T.2    Stephens, L.C.3    Brock, W.A.4    Milas, L.5    Plunkett, W.6
  • 104
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • O'Connell MJ, Martenson JA, Wieand HS, Krook JE, MacDonald JS, Haller DG, et al. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 1994;331:502-7.
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3    Krook, J.E.4    MacDonald, J.S.5    Haller, D.G.6
  • 106
    • 44949278031 scopus 로고
    • Invited response to letter by Dr. Rodriguez and colleagues
    • Lawrence TS, Ensminger WD. Invited response to letter by Dr. Rodriguez and colleagues. Int J Radiat Oncol Biol Phys 1991;20:1379-82.
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , pp. 1379-1382
    • Lawrence, T.S.1    Ensminger, W.D.2
  • 107
    • 0027054126 scopus 로고
    • The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines
    • Vokes EE, Beckett M, Karrison T, Weichselbaum RR. The interaction of 5-fluorouracil, hydroxyurea, and radiation in two human head and neck cancer cell lines. Oncology 1992;49:454-60.
    • (1992) Oncology , vol.49 , pp. 454-460
    • Vokes, E.E.1    Beckett, M.2    Karrison, T.3    Weichselbaum, R.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.