5-Fluoroindole-3-acetic acid: A prodrug activated by a peroxidase with potential for use in targeted cancer therapy

Biochemical Pharmacology

Volumn 63, Issue 2, 2002, Pages 265-272

  Folkes, Lisa K ^a   Greco, Olga ^a   Dachs, Gabi U ^a   Stratford, Michael R L ^a   Wardman, Peter ^a  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

Author keywords

5 Fluoroindole 3 acetic acid; Horseradish peroxidase; Indole 3 acetic acid; Peroxidase; Prodrug: 3 Methylene 2 oxindole

Indexed keywords

5 FLUORO 3 METHYLENE 2 OXINDOLE; 5 FLUOROINDOLE 3 ACETIC ACID; ACETIC ACID DERIVATIVE; DNA; GLUTATHIONE; HORSERADISH PEROXIDASE; INDOLE DERIVATIVE; INDOLEACETIC ACID; PRODRUG; THIOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CANCER THERAPY; CARCINOMA CELL; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EFFECT; DRUG OXIDATION; DRUG TARGETING; FEMALE; FLUORINATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; FEMALE; FLUORINE; GLUTATHIONE; HT29 CELLS; HUMANS; INDOLEACETIC ACIDS; MICE; MICE, INBRED CBA; NEOPLASMS, EXPERIMENTAL; OXIDATION-REDUCTION; PEROXIDASES; PRODRUGS;

EID: 0037081743     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00868-1     Document Type: Article

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