Involvement of Fas (CD95/APO-1) and Fas ligand in apoptosis induced by ganciclovir treatment of tumor cells transduced with herpes simplex virus thymidine kinase

Gene Therapy

Volumn 6, Issue 3, 1999, Pages 420-431

  Wei, S J ^d   Chao, Y ^a   Shih, Y L ^b   Yang, D M ^b   Hung, Y M ^b   Yang, W K ^b,c  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^d NONE

Author keywords

Apoptosis; Caspase 3; Fas; FasL; Ganciclovir; HSVtk

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ANTIVIRUS AGENT; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CHIMERIC PROTEIN; FAS ANTIGEN; FAS LIGAND; GANCICLOVIR; PROTEIN P53; THYMIDINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; CULTURE MEDIUM; DOSE RESPONSE; FEMALE; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; IMMUNOBLOTTING; LIVER CELL CARCINOMA; MELANOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOMA; TUMOR CELL;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BIOLOGICAL MARKERS; CASPASE 3; CASPASES; ENZYME ACTIVATION; FAS LIGAND PROTEIN; FEMALE; GANCICLOVIR; GENE EXPRESSION; GENE THERAPY; IMMUNOBLOTTING; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; NEOPLASMS; PRODRUGS; SIGNAL TRANSDUCTION; THYMIDINE KINASE; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0033067561     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300817     Document Type: Article

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