메뉴 건너뛰기




Volumn 4, Issue 9, 1997, Pages 909-917

Retinoids augment the bystander effect in vitro and in vivo in herpes simplex virus thymidine kinase/ganciclovir-mediated gene therapy

Author keywords

Bystander effect; Ganciclovir; Gap junctions; Gene therapy; HSV thymidine kinase; Retinoids

Indexed keywords

GANCICLOVIR; GAP JUNCTION PROTEIN; PRODRUG; RETINOID; THYMIDINE KINASE; VIRUS VECTOR;

EID: 0030801745     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300477     Document Type: Article
Times cited : (62)

References (39)
  • 1
    • 0028702018 scopus 로고
    • Drug sensitivity ('suicide') genes for selective cancer therapy
    • Moolten FL. Drug sensitivity ('suicide') genes for selective cancer therapy. Cancer Gene Ther 1994; 1: 279-287.
    • (1994) Cancer Gene Ther , vol.1 , pp. 279-287
    • Moolten, F.L.1
  • 2
    • 0026718123 scopus 로고
    • Human gene therapy comes of age
    • Miller AD. Human gene therapy comes of age. Nature 1992; 357: 455-460.
    • (1992) Nature , vol.357 , pp. 455-460
    • Miller, A.D.1
  • 3
    • 0027961080 scopus 로고
    • In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene
    • Guzman RJ et al. In vivo suppression of injury-induced vascular smooth muscle cell accumulation using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA 1994; 91: 10732-10736.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10732-10736
    • Guzman, R.J.1
  • 4
    • 0029171691 scopus 로고
    • Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery
    • Chang MW et al. Adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene inhibits vascular smooth muscle cell proliferation and neointima formation following balloon angioplasty of the rat carotid artery. Mol Med 1995; 1: 172-181.
    • (1995) Mol Med , vol.1 , pp. 172-181
    • Chang, M.W.1
  • 5
    • 0025241769 scopus 로고
    • Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
    • Moolten FL, Wells JM. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors. J Natl Cancer Inst 1990; 82: 297-300.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 297-300
    • Moolten, F.L.1    Wells, J.M.2
  • 6
    • 0024041143 scopus 로고
    • Antiviral activity and mechanism of action of ganciclovir
    • Matthews T, Boehme R. Antiviral activity and mechanism of action of ganciclovir. Rev Infect Dis 1988; 10: S490-S494.
    • (1988) Rev Infect Dis , vol.10
    • Matthews, T.1    Boehme, R.2
  • 7
    • 0028860037 scopus 로고
    • Bystander killing' induces apoptosis and is inhibited by forskolin
    • Samejima Y, Meruelo D. 'Bystander killing' induces apoptosis and is inhibited by forskolin. Gene Therapy 1995; 2: 50-58.
    • (1995) Gene Therapy , vol.2 , pp. 50-58
    • Samejima, Y.1    Meruelo, D.2
  • 8
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver KW et al. In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science 1992; 256: 1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1
  • 9
    • 0027483695 scopus 로고
    • The bystander effect: Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman SM et al. The bystander effect: tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-5283.
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
    • Freeman, S.M.1
  • 10
    • 0028340984 scopus 로고
    • Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma
    • Smythe WR et al. Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. Ann Thor Surg 1994; 57: 1395-1401.
    • (1994) Ann Thor Surg , vol.57 , pp. 1395-1401
    • Smythe, W.R.1
  • 11
    • 0029340302 scopus 로고
    • Gene therapy using adenovirus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer
    • Hwang HC et al. Gene therapy using adenovirus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer. Am J Respir Cell Mol Biol 1995; 13: 7-16.
    • (1995) Am J Respir Cell Mol Biol , vol.13 , pp. 7-16
    • Hwang, H.C.1
  • 12
    • 0029076201 scopus 로고
    • Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene
    • Smythe WR et al. Treatment of experimental human mesothelioma using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg 1995; 222: 78-86.
    • (1995) Ann Surg , vol.222 , pp. 78-86
    • Smythe, W.R.1
  • 13
    • 0030046154 scopus 로고    scopus 로고
    • Treatment of malignant pleural mesothelioma in an immunocompetent rat model utilizing adenovirus-mediated gene therapy
    • Elshami AA et al. Treatment of malignant pleural mesothelioma in an immunocompetent rat model utilizing adenovirus-mediated gene therapy. Hum Gene Ther 1996; 7: 141-148.
    • (1996) Hum Gene Ther , vol.7 , pp. 141-148
    • Elshami, A.A.1
  • 14
    • 0025899005 scopus 로고
    • Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene
    • Ezzedine ZD et al. Selective killing of glioma cells in culture and in vivo by retrovirus transfer of the herpes simplex virus thymidine kinase gene. New Biol 1991; 3: 608-614.
    • (1991) New Biol , vol.3 , pp. 608-614
    • Ezzedine, Z.D.1
  • 15
    • 0028116059 scopus 로고
    • Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by type-specific expression of herpes simplex thymidine kinase gene
    • Osaki T et al. Gene therapy for carcinoembryonic antigen-producing human lung cancer cells by type-specific expression of herpes simplex thymidine kinase gene. Cancer Res 1994; 53: 5258-5261.
    • (1994) Cancer Res , vol.53 , pp. 5258-5261
    • Osaki, T.1
  • 16
    • 0029913138 scopus 로고    scopus 로고
    • Gap junctions play a role in the bystander effect of the herpes simplex virus thymidine kinase/ganciclovir system in vitro
    • Elshami AA et al. Gap junctions play a role in the bystander effect of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Therapy 1996; 3: 85-92.
    • (1996) Gene Therapy , vol.3 , pp. 85-92
    • Elshami, A.A.1
  • 17
    • 0027787053 scopus 로고
    • In vivo evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy
    • Li Bi W, Parysek LM, Warnick R, Stambrook PJ. In vivo evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy. Hum Gene Ther 1993; 4: 725-731.
    • (1993) Hum Gene Ther , vol.4 , pp. 725-731
    • Li Bi, W.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 18
    • 0028864786 scopus 로고
    • The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro
    • Fick J et al. The extent of heterocellular communication mediated by gap junctions is predictive of bystander tumor cytotoxicity in vitro. Proc Natl Acad Sci USA 1995; 92: 11071-11075.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11071-11075
    • Fick, J.1
  • 19
    • 0029996360 scopus 로고    scopus 로고
    • Bystander killing of cancer by herpes simplex virus thymidine kinase gene is mediated by connexins
    • Mesnil M et al. Bystander killing of cancer by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc Natl Acad Sci USA 1996; 93: 1831-1835.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1831-1835
    • Mesnil, M.1
  • 20
    • 0025963272 scopus 로고
    • Gap junctions: New tools, new answers, new questions
    • Bennett MVL et al. Gap junctions: new tools, new answers, new questions. Neuron 1991; 6: 305-320.
    • (1991) Neuron , vol.6 , pp. 305-320
    • Bennett, M.V.L.1
  • 21
    • 0027410499 scopus 로고
    • Gap junctions in the brain: Where, what type, how many and why?
    • Dermietzel R, Spray DC. Gap junctions in the brain: where, what type, how many and why? Trends Neurosci 1993; 16: 186-192.
    • (1993) Trends Neurosci , vol.16 , pp. 186-192
    • Dermietzel, R.1    Spray, D.C.2
  • 22
    • 0027945565 scopus 로고
    • Expression of cell adhesion molecules and connexins in gap junctional intercellular communication deficient human mesothelioma tumour cell lines and communication competent primary mesothelial cells
    • Pelin K, Hirvonen A, Linnainmaa K. Expression of cell adhesion molecules and connexins in gap junctional intercellular communication deficient human mesothelioma tumour cell lines and communication competent primary mesothelial cells. Carcinogenesis 1994; 15: 2673-2675.
    • (1994) Carcinogenesis , vol.15 , pp. 2673-2675
    • Pelin, K.1    Hirvonen, A.2    Linnainmaa, K.3
  • 23
    • 0028951684 scopus 로고
    • Upregulation of gap junctional communication and connexin43 gene expression by carotenoids in human dermal fibroblasts but not in human keratinocytes
    • Zhang L, Acevedo P, Guo H, Bertram JS. Upregulation of gap junctional communication and connexin43 gene expression by carotenoids in human dermal fibroblasts but not in human keratinocytes. Mol Carcinogenesis 1995; 12: 50-58.
    • (1995) Mol Carcinogenesis , vol.12 , pp. 50-58
    • Zhang, L.1    Acevedo, P.2    Guo, H.3    Bertram, J.S.4
  • 24
    • 0026674833 scopus 로고
    • Gap-junctional protein connexin43 is expressed in dermis and epidermis of human skin: Differential modulation by retinoids
    • Guo H, Acevedo P, Parsa FD, Bertram JS. Gap-junctional protein connexin43 is expressed in dermis and epidermis of human skin: differential modulation by retinoids. J Invest Dermatol 1992; 99: 460-467.
    • (1992) J Invest Dermatol , vol.99 , pp. 460-467
    • Guo, H.1    Acevedo, P.2    Parsa, F.D.3    Bertram, J.S.4
  • 25
    • 0025775260 scopus 로고
    • Differential regulation of communication by retinoic acid in homologous and heterologous junctions between normal and transformed cells
    • Mehta PP, Loewenstein WR. Differential regulation of communication by retinoic acid in homologous and heterologous junctions between normal and transformed cells. J Cell Biol 1991; 113: 371-379.
    • (1991) J Cell Biol , vol.113 , pp. 371-379
    • Mehta, P.P.1    Loewenstein, W.R.2
  • 26
    • 0027318152 scopus 로고
    • Specificity of gap junction communication among human mammary cells and connexin transfectants in culture
    • Tomasetto C et al. Specificity of gap junction communication among human mammary cells and connexin transfectants in culture. J Cell Biol 1993; 122: 157-167.
    • (1993) J Cell Biol , vol.122 , pp. 157-167
    • Tomasetto, C.1
  • 27
    • 0023188916 scopus 로고
    • Retinoids as preventive and therapeutic anticancer agents (part I)
    • Lippman SM, Kessler JF, Meyskens FL. Retinoids as preventive and therapeutic anticancer agents (part I). Cancer Treat Rep 1987; 4: 391-405.
    • (1987) Cancer Treat Rep , vol.4 , pp. 391-405
    • Lippman, S.M.1    Kessler, J.F.2    Meyskens, F.L.3
  • 28
    • 0025132840 scopus 로고
    • Transport and storage of vitamin A
    • Blomhoff R et al. Transport and storage of vitamin A. Science 1990; 250: 399-404.
    • (1990) Science , vol.250 , pp. 399-404
    • Blomhoff, R.1
  • 29
    • 0022001964 scopus 로고
    • Quantification of retinoic acid by gas-liquid chromatography-mass spectrometry: Total versus all-trans-retinoic acid in human plasma
    • Napoli JL et al. Quantification of retinoic acid by gas-liquid chromatography-mass spectrometry: total versus all-trans-retinoic acid in human plasma. J Lipid Res 1985; 26: 387-392.
    • (1985) J Lipid Res , vol.26 , pp. 387-392
    • Napoli, J.L.1
  • 31
    • 0025611734 scopus 로고
    • Retinoid-enhanced gap junctional communication is achieved by increased levels of connexin 43 mRNA and protein
    • Rogers M et al. Retinoid-enhanced gap junctional communication is achieved by increased levels of connexin 43 mRNA and protein. Mol Carcinogenesis 1990; 3: 335-343.
    • (1990) Mol Carcinogenesis , vol.3 , pp. 335-343
    • Rogers, M.1
  • 32
    • 0017612451 scopus 로고
    • Inhibitory effects of retinoic acid or retinyl acetate on the growth of untransformed, transformed, and tumor cells in vitro
    • Lotan R, Nicolson GL. Inhibitory effects of retinoic acid or retinyl acetate on the growth of untransformed, transformed, and tumor cells in vitro. J Natl Cancer Inst 1977; 59: 1717-1722.
    • (1977) J Natl Cancer Inst , vol.59 , pp. 1717-1722
    • Lotan, R.1    Nicolson, G.L.2
  • 33
    • 0024563451 scopus 로고
    • The actions of retinoids on cellular growth correlate with their actions on gap junctional communication
    • Mehta PP, Bertram JS, Loewenstein WR. The actions of retinoids on cellular growth correlate with their actions on gap junctional communication. J Cell Biol 1989; 108: 1053-1065.
    • (1989) J Cell Biol , vol.108 , pp. 1053-1065
    • Mehta, P.P.1    Bertram, J.S.2    Loewenstein, W.R.3
  • 34
    • 0028340984 scopus 로고
    • Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma
    • Smythe WR et al. Successful adenovirus-mediated gene transfer in an in vivo model of human malignant mesothelioma. Ann Thorac Surg 1994; 57: 1395-1401.
    • (1994) Ann Thorac Surg , vol.57 , pp. 1395-1401
    • Smythe, W.R.1
  • 35
    • 0026620586 scopus 로고
    • Establishment of a murine model of malignant mesothelioma
    • Davis MR et al. Establishment of a murine model of malignant mesothelioma. Int J Cancer 1992; 52: 881-887.
    • (1992) Int J Cancer , vol.52 , pp. 881-887
    • Davis, M.R.1
  • 36
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • Miller AD, Rosman GJ. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989; 7: 980-990.
    • (1989) Biotechniques , vol.7 , pp. 980-990
    • Miller, A.D.1    Rosman, G.J.2
  • 37
    • 0027255704 scopus 로고
    • Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenovirus
    • Englehardt JF et al. Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenovirus. Nat Genet 1993; 4: 27-34.
    • (1993) Nat Genet , vol.4 , pp. 27-34
    • Englehardt, J.F.1
  • 38
    • 0028348372 scopus 로고
    • Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: An effective in vitro drug sensitization system
    • Smythe WR et al. Use of recombinant adenovirus to transfer the herpes simplex virus thymidine kinase (HSVtk) gene to thoracic neoplasms: an effective in vitro drug sensitization system. Cancer Res 1994; 54: 2055-2059.
    • (1994) Cancer Res , vol.54 , pp. 2055-2059
    • Smythe, W.R.1
  • 39
    • 84965822602 scopus 로고
    • Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay
    • Alley MC et al. Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay. Cancer Res 1988; 48: 589-601.
    • (1988) Cancer Res , vol.48 , pp. 589-601
    • Alley, M.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.