-
1
-
-
0020530463
-
Activation of 5′-deoxy-5-fluorouridine by thymidine phosphorylase in human tumor tissues
-
Tokyo
-
Kono, H., Hara, Y., Sugata, S. Karube, Y., Matsushima, Y., and Ishitsuka, H. Activation of 5′-deoxy-5-fluorouridine by thymidine phosphorylase in human tumor tissues. Chem. Pharm. Bull. (Tokyo), 31: 175-178, 1983.
-
(1983)
Chem. Pharm. Bull.
, vol.31
, pp. 175-178
-
-
Kono, H.1
Hara, Y.2
Sugata, S.3
Karube, Y.4
Matsushima, Y.5
Ishitsuka, H.6
-
2
-
-
0032127244
-
Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentrated in human liver and cancer tissue
-
in press
-
Miwa, M., Ura, M., Nishida, M., Sawada, N., Ishikawa, T., Mori, K., Shimma, N., Umeda, I., and Ishitsuka, H. Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumors by enzymes concentrated in human liver and cancer tissue. Eur. J. Cancer, in press, 1998.
-
(1998)
Eur. J. Cancer
-
-
Miwa, M.1
Ura, M.2
Nishida, M.3
Sawada, N.4
Ishikawa, T.5
Mori, K.6
Shimma, N.7
Umeda, I.8
Ishitsuka, H.9
-
3
-
-
0028957177
-
Role of thymidine phosphorylase activity in the angiogenic effect of platelet-derived endothelial cell growth factor/thymidine phosphorylase
-
Miyadera, K., Sumizawa, T., Haraguchi, M., Yoshida, H., Konstanty, W., Yamada, Y., and Akiyama, S. Role of thymidine phosphorylase activity in the angiogenic effect of platelet-derived endothelial cell growth factor/thymidine phosphorylase. Cancer Res., 55: 1687-1690, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 1687-1690
-
-
Miyadera, K.1
Sumizawa, T.2
Haraguchi, M.3
Yoshida, H.4
Konstanty, W.5
Yamada, Y.6
Akiyama, S.7
-
4
-
-
0030027519
-
The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium
-
Fox, S. B., Westwood, M., Moghaddam, A., Comley, M., Turley, H., Whitehouse, R. M., Bicknell, R., Gatter, K. C., and Harris, A. L. The angiogenic factor platelet-derived endothelial cell growth factor/thymidine phosphorylase is up-regulated in breast cancer epithelium and endothelium. Br. J. Cancer, 73: 275-280, 1996.
-
(1996)
Br. J. Cancer
, vol.73
, pp. 275-280
-
-
Fox, S.B.1
Westwood, M.2
Moghaddam, A.3
Comley, M.4
Turley, H.5
Whitehouse, R.M.6
Bicknell, R.7
Gatter, K.C.8
Harris, A.L.9
-
5
-
-
0029806438
-
Preparation of anti-human thymidine phosphorylase monoclonal antibody useful for detecting the enzyme levels in tumor tissues
-
Nishida, M., Hino, A., Mori, K., Matsumoto, T., Yoshikubo, T., and Ishitsuka, H. Preparation of anti-human thymidine phosphorylase monoclonal antibody useful for detecting the enzyme levels in tumor tissues. Biol. Pharm. Bull., 19: 1407-1411, 1996.
-
(1996)
Biol. Pharm. Bull.
, vol.19
, pp. 1407-1411
-
-
Nishida, M.1
Hino, A.2
Mori, K.3
Matsumoto, T.4
Yoshikubo, T.5
Ishitsuka, H.6
-
6
-
-
0029790295
-
Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma
-
Takebayashi, Y., Akiyama, S., Akiba, S., Yamada, K., Miyadera, K., Sumizawa, T., Yamada, Y., Murata, F., and Aikou, T. Clinicopathologic and prognostic significance of an angiogenic factor, thymidine phosphorylase, in human colorectal carcinoma. J. Natl. Cancer Inst., 88: 1110-1117, 1996.
-
(1996)
J. Natl. Cancer Inst.
, vol.88
, pp. 1110-1117
-
-
Takebayashi, Y.1
Akiyama, S.2
Akiba, S.3
Yamada, K.4
Miyadera, K.5
Sumizawa, T.6
Yamada, Y.7
Murata, F.8
Aikou, T.9
-
7
-
-
0027445159
-
Sensitivity of human KB cells expressing platelet-derived endothelial cell growth factor to pyrimidine antimetabolites
-
Haraguchi, M., Furukawa, T., Sumizawa, T., and Akiyama, S. Sensitivity of human KB cells expressing platelet-derived endothelial cell growth factor to pyrimidine antimetabolites. Cancer Res., 53: 5680-5682, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 5680-5682
-
-
Haraguchi, M.1
Furukawa, T.2
Sumizawa, T.3
Akiyama, S.4
-
8
-
-
0022969597
-
Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells
-
Tokyo
-
Miwa, M., Cook, A., and Ishitsuka, H. Enzymatic cleavage of various fluorinated pyrimidine nucleosides to 5-fluorouracil and their antiproliferative activities in human and murine tumor cells. Chem. Pharm. Bull. (Tokyo), 34: 4225-4232, 1986.
-
(1986)
Chem. Pharm. Bull.
, vol.34
, pp. 4225-4232
-
-
Miwa, M.1
Cook, A.2
Ishitsuka, H.3
-
9
-
-
0027313603
-
Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine
-
Eda, H., Fujimoto, K., Watanabe, S., Ura, M., Hino, A., Tanaka, Y., Wada, K., and Ishitsuka, H. Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine. Cancer Chemother. Pharmacol., 32: 333-338, 1993.
-
(1993)
Cancer Chemother. Pharmacol.
, vol.32
, pp. 333-338
-
-
Eda, H.1
Fujimoto, K.2
Watanabe, S.3
Ura, M.4
Hino, A.5
Tanaka, Y.6
Wada, K.7
Ishitsuka, H.8
-
10
-
-
0027509829
-
Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5′-deoxy-5-fluorouridine
-
Eda, H., Fujimoto, K., Watanabe, S., Ishikawa, T., Ohiwa, T., Tatsuno, K., Tanaka, Y., and Ishitsuka, H. Cytokines induce uridine phosphorylase in mouse colon 26 carcinoma cells and make the cells more susceptible to 5′-deoxy-5-fluorouridine. Jpn. J. Cancer Res., 84: 341-347, 1993.
-
(1993)
Jpn. J. Cancer Res.
, vol.84
, pp. 341-347
-
-
Eda, H.1
Fujimoto, K.2
Watanabe, S.3
Ishikawa, T.4
Ohiwa, T.5
Tatsuno, K.6
Tanaka, Y.7
Ishitsuka, H.8
-
11
-
-
0026556166
-
Interactions of interferon-α2a with 5′-deoxy-5-fluorouridine in colorectal cancer cells in vitro
-
Tevaerai, H. T., Laurent, P. L., Suardet, L., Eliason, J. F., Givel, J. C., and Odartchenko, N. Interactions of interferon-α2a with 5′-deoxy-5-fluorouridine in colorectal cancer cells in vitro. Eur. J. Cancer, 28: 368-372, 1992.
-
(1992)
Eur. J. Cancer
, vol.28
, pp. 368-372
-
-
Tevaerai, H.T.1
Laurent, P.L.2
Suardet, L.3
Eliason, J.F.4
Givel, J.C.5
Odartchenko, N.6
-
12
-
-
0026600296
-
Stimulation of 5-fluorouracil metabolic activation by interferon-α2a in human colon carcinoma cells
-
Schwartz, E. L., Hoffman, M., O'Connor, C. J., and Walder, S. Stimulation of 5-fluorouracil metabolic activation by interferon-α2a in human colon carcinoma cells. Biochem. Biophys. Res. Commun., 182: 1232-1239, 1992.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.182
, pp. 1232-1239
-
-
Schwartz, E.L.1
Hoffman, M.2
O'Connor, C.J.3
Walder, S.4
-
13
-
-
0344814477
-
Augmentation of antitumor activity of 5′-deoxy-5-fluorouridine by IL-12 through the up-regulation of pyrimidine nucleoside phosphorylase in murine tumor models
-
Tanaka, Y., Endo, M., Ouchi, K., Mori, K., and Ishitsuka, H. Augmentation of antitumor activity of 5′-deoxy-5-fluorouridine by IL-12 through the up-regulation of pyrimidine nucleoside phosphorylase in murine tumor models. Eur. J. Cancer, 33 (Suppl. 8): S176-S177, 1997.
-
(1997)
Eur. J. Cancer
, vol.33
, Issue.8 SUPPL.
-
-
Tanaka, Y.1
Endo, M.2
Ouchi, K.3
Mori, K.4
Ishitsuka, H.5
-
14
-
-
0007522090
-
Capecitabine and the dThdPase up-regulators IFNγ or Taxol showed synergistic activity in human cancer xenografts
-
Ishitsuka H., Ishikawa, T., Fukase, Y., Sawada, N., Tanaka, Y., Ouchi, K., Yoshikubo, T., and Nishida, M. Capecitabine and the dThdPase up-regulators IFNγ or Taxol showed synergistic activity in human cancer xenografts. Proc. Am. Assoc. Cancer Res., 37: 2766, 1996.
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 2766
-
-
Ishitsuka, H.1
Ishikawa, T.2
Fukase, Y.3
Sawada, N.4
Tanaka, Y.5
Ouchi, K.6
Yoshikubo, T.7
Nishida, M.8
-
15
-
-
0025319864
-
Shared actions of endotoxin and Taxol on TNF receptors and TNF release
-
Washington DC
-
Ding, A. H., Porteu, F., Sanchez, E., and Nathan C. N. Shared actions of endotoxin and Taxol on TNF receptors and TNF release. Science (Washington DC), 248: 370-372, 1990.
-
(1990)
Science
, vol.248
, pp. 370-372
-
-
Ding, A.H.1
Porteu, F.2
Sanchez, E.3
Nathan, C.N.4
-
16
-
-
0026686641
-
Taxol, a microtubule-stabilizing antineo-plastic agent, induces expression of tumor necrosis factor α and interleukin-1 in macrophages
-
Bogdan, C., and Ding, A. Taxol, a microtubule-stabilizing antineo-plastic agent, induces expression of tumor necrosis factor α and interleukin-1 in macrophages. J. Leukocyte Biol., 52: 119-121, 1992.
-
(1992)
J. Leukocyte Biol.
, vol.52
, pp. 119-121
-
-
Bogdan, C.1
Ding, A.2
-
17
-
-
0028061972
-
Relationship between the structure of Taxol and other taxanes on induction of tumor necrosis factor-α gene expression and cytotoxicity
-
Burkhart, C. A., Berman, J. W., Swindell, C. S., and Horwitz, S. B. Relationship between the structure of Taxol and other taxanes on induction of tumor necrosis factor-α gene expression and cytotoxicity. Cancer Res., 54: 5779-5782, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 5779-5782
-
-
Burkhart, C.A.1
Berman, J.W.2
Swindell, C.S.3
Horwitz, S.B.4
-
18
-
-
0025263860
-
Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice
-
Tanaka, Y., Eda, H., Tanaka, T., Udagawa, T., Ishikawa, T., Horii, I., and Ishitsuka, H. Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res., 50: 2290-2295, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 2290-2295
-
-
Tanaka, Y.1
Eda, H.2
Tanaka, T.3
Udagawa, T.4
Ishikawa, T.5
Horii, I.6
Ishitsuka, H.7
-
19
-
-
0004306765
-
-
European Patent Application No. 92121538.0, 1992
-
Arasaki, M., Ishitsuka, H., Kuruma, I., Miwa, M., Murasaki, C., Shimma, N., and Umeda, I. N-Oxycarbonyl substituted 5′-deoxy-5-fluorocytidines. European Patent Application No. 92121538.0, 1992.
-
N-Oxycarbonyl Substituted 5′-deoxy-5-fluorocytidines
-
-
Arasaki, M.1
Ishitsuka, H.2
Kuruma, I.3
Miwa, M.4
Murasaki, C.5
Shimma, N.6
Umeda, I.7
-
20
-
-
0345169368
-
Characteristics of human colon cancer cells transfected with thymidine phosphorylase gene
-
Eda, H., Hasegawa, M., Tatsuno, K., Matsumoto, T., Watanabe, S., Uchida, T., and Ishitsuka, H. Characteristics of human colon cancer cells transfected with thymidine phosphorylase gene (in Japanese). J. Jpn. Soc. Cancer Ther., 29: 164, 1994.
-
(1994)
J. Jpn. Soc. Cancer Ther.
, vol.29
, pp. 164
-
-
Eda, H.1
Hasegawa, M.2
Tatsuno, K.3
Matsumoto, T.4
Watanabe, S.5
Uchida, T.6
Ishitsuka, H.7
-
21
-
-
71849104860
-
Protein measurement with the Folin phenol reagent
-
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem., 193: 265-275, 1951.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosebrough, N.J.2
Farr, A.L.3
Randall, R.J.4
|