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Volumn 385, Issue 1, 2001, Pages 203-208

Demonstration of the activation of prodrug CB 1954 using human DT-diaphorase mutant Q104Y-transfected MDA-MB-231 cells and mouse xenograft model

(4) Wu, Kebin a Eng, Elizabeth a Knox, Richard b Chen, Shiuan a

a CITY OF HOPE NATIONAL MEDICAL CENTER (United States)

b UNIVERSITY OF GREENWICH (United Kingdom)

Author keywords

CB 1954; DT diaphorase; MDA MB 231 cells; Mouse xenograft; Prodrug activation

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; COMPLEMENTARY DNA; DIHYDROLIPOAMIDE DEHYDROGENASE; GLUTAMINE; PRODRUG; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BREAST CANCER; CANCER CELL; CATALYSIS; CELL CLONE; CELL KILLING; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; EXPRESSION VECTOR; FEMALE; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; XENOGRAFT;

MUS MUSCULUS;

EID: 0034779947 PISSN: 00039861 EISSN: None Source Type: Journal
DOI: 10.1006/abbi.2000.2144 Document Type: Article

Times cited : (11)

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