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Volumn 6, Issue 1, 1999, Pages 12-21

Intercellular delivery of thymidine kinase prodrug activating enzyme by the herpes simplex virus protein, VP22

Author keywords

GCV; HSV 1; Protein delivery; tk; VP22

Indexed keywords

CARRIER PROTEIN; GANCICLOVIR; PRODRUG; THYMIDINE KINASE; VIRUS FUSION PROTEIN;

EID: 0032896455     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300838     Document Type: Article
Times cited : (162)

References (26)
  • 1
    • 0030984929 scopus 로고    scopus 로고
    • The TMC Worldwide Gene Therapy Enrollment Report, end 1996
    • Marcel T, Grausz JD. The TMC Worldwide Gene Therapy Enrollment Report, end 1996. Hum Gene Ther 1997; 8: 775-800.
    • (1997) Hum Gene Ther , vol.8 , pp. 775-800
    • Marcel, T.1    Grausz, J.D.2
  • 2
    • 0031463632 scopus 로고    scopus 로고
    • Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells
    • Ram Z et al. Therapy of malignant brain tumors by intratumoral implantation of retroviral vector-producing cells. Nature Med 1997; 3: 1354-1361.
    • (1997) Nature Med , vol.3 , pp. 1354-1361
    • Ram, Z.1
  • 3
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy problems, promises and prospects
    • Verma I, Somia N. Gene therapy problems, promises and prospects. Nature 1997; 389: 239-242.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.1    Somia, N.2
  • 4
    • 0027787053 scopus 로고
    • In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy
    • Bi WL, Parysek LM, Warnick R, Stambrook PJ. In vitro evidence that metabolic cooperation is responsible for the bystander effect observed with HSVtk retroviral gene therapy. Hum Gene Ther 1993; 4: 725-731.
    • (1993) Hum Gene Ther , vol.4 , pp. 725-731
    • Bi, W.L.1    Parysek, L.M.2    Warnick, R.3    Stambrook, P.J.4
  • 5
    • 0027483695 scopus 로고
    • The 'bystander effect': Tumor regression when a fraction of the tumor mass is genetically modified
    • Freeman SM et al. The 'bystander effect': tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-5283.
    • (1993) Cancer Res , vol.53 , pp. 5274-5283
    • Freeman, S.M.1
  • 6
    • 0030937485 scopus 로고    scopus 로고
    • Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo
    • Dilber MS et al. Gap junctions promote the bystander effect of herpes simplex virus thymidine kinase in vivo. Cancer Res 1997; 57: 1523-1528.
    • (1997) Cancer Res , vol.57 , pp. 1523-1528
    • Dilber, M.S.1
  • 7
    • 0030996607 scopus 로고    scopus 로고
    • Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment
    • Ishii-Morita H et al. Mechanism of 'bystander effect' killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment. Gene Therapy 1997; 4: 244-251.
    • (1997) Gene Therapy , vol.4 , pp. 244-251
    • Ishii-Morita, H.1
  • 8
    • 0028278801 scopus 로고
    • The role of gap junctional intercellular communication in neoplasia
    • Ruch RJ. The role of gap junctional intercellular communication in neoplasia. Ann Clin Lab Sci 1994; 24: 216-231.
    • (1994) Ann Clin Lab Sci , vol.24 , pp. 216-231
    • Ruch, R.J.1
  • 9
    • 15844409182 scopus 로고    scopus 로고
    • Protein and messenger RNA expression of connexin43 in astrocytomas: Implications in brain tumor gene therapy
    • Shinoura N et al. Protein and messenger RNA expression of connexin43 in astrocytomas: implications in brain tumor gene therapy. J Neurosurg 1996; 84: 839-845.
    • (1996) J Neurosurg , vol.84 , pp. 839-845
    • Shinoura, N.1
  • 10
    • 0031471203 scopus 로고    scopus 로고
    • Intercellular trafficking and protein delivery by a herpesvirus structural protein
    • Elliott G, O'Hare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 1997; 88: 223-233.
    • (1997) Cell , vol.88 , pp. 223-233
    • Elliott, G.1    O'Hare, P.2
  • 11
    • 0030757097 scopus 로고    scopus 로고
    • The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk:) gene is dependent on connexin expression and cell communication via gap junctions
    • Vrionis FD et al. The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk:) gene is dependent on connexin expression and cell communication via gap junctions. Gene Therapy 1997; 4: 577-585.
    • (1997) Gene Therapy , vol.4 , pp. 577-585
    • Vrionis, F.D.1
  • 12
    • 17344382938 scopus 로고    scopus 로고
    • Tissue-specific expression of HSVtk gene can induce efficient antitumor effect and protective immunity to wild-type hepatocellular carcinoma
    • Kuriyama S et al. Tissue-specific expression of HSVtk gene can induce efficient antitumor effect and protective immunity to wild-type hepatocellular carcinoma. Int J Cancer 1997; 71: 470-475.
    • (1997) Int J Cancer , vol.71 , pp. 470-475
    • Kuriyama, S.1
  • 13
    • 0027255414 scopus 로고
    • Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA
    • Vile RG, Hart IR. Use of tissue-specific expression of the herpes simplex virus thymidine kinase gene to inhibit growth of established murine melanomas following direct intratumoral injection of DNA. Cancer Res 1993; 53: 3860-3864.
    • (1993) Cancer Res , vol.53 , pp. 3860-3864
    • Vile, R.G.1    Hart, I.R.2
  • 14
    • 0031983980 scopus 로고    scopus 로고
    • In vitro and in vivo antitumor effects of retrovirus-mediated herpes simplex thymidine kinase gene-transfer in human medulloblastoma
    • Rosolen A et al. In vitro and in vivo antitumor effects of retrovirus-mediated herpes simplex thymidine kinase gene-transfer in human medulloblastoma. Gene Therapy 1998; 5: 113-120.
    • (1998) Gene Therapy , vol.5 , pp. 113-120
    • Rosolen, A.1
  • 15
    • 0030729896 scopus 로고    scopus 로고
    • HSV-1 thymidine kinase gene therapy for colorectal adenocarcinoma-derived peritoneal carcinomatosis
    • Lechanteur C et al. HSV-1 thymidine kinase gene therapy for colorectal adenocarcinoma-derived peritoneal carcinomatosis. Gene Therapy 1997; 4: 1189-1194.
    • (1997) Gene Therapy , vol.4 , pp. 1189-1194
    • Lechanteur, C.1
  • 16
    • 0031836938 scopus 로고    scopus 로고
    • Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression
    • Melcher A et al. Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression. Nature Med 1998; 4: 581-587.
    • (1998) Nature Med , vol.4 , pp. 581-587
    • Melcher, A.1
  • 17
    • 0029977047 scopus 로고    scopus 로고
    • Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpes virus thymidine kinase occurs by p53-independent apoptosis
    • Wallace H et al. Ganciclovir-induced ablation non-proliferating thyrocytes expressing herpes virus thymidine kinase occurs by p53-independent apoptosis. Oncogens 1996; 13: 55-61.
    • (1996) Oncogens , vol.13 , pp. 55-61
    • Wallace, H.1
  • 18
    • 0029997766 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells
    • Hamel W, Magnelli L, Chiarugi VP, Isreal MA. Herpes simplex virus thymidine kinase/ganciclovir-mediated apoptotic death of bystander cells. Cancer Res 1996; 56: 2697-2702.
    • (1996) Cancer Res , vol.56 , pp. 2697-2702
    • Hamel, W.1    Magnelli, L.2    Chiarugi, V.P.3    Isreal, M.A.4
  • 19
    • 0028075655 scopus 로고
    • Systemic gene therapy of murine melanoma using tissue-specific expression of the HSVtk gene involves an immune component
    • Vile RG et al. Systemic gene therapy of murine melanoma using tissue-specific expression of the HSVtk gene involves an immune component. Cancer Res 1994; 54: 6228-6234.
    • (1994) Cancer Res , vol.54 , pp. 6228-6234
    • Vile, R.G.1
  • 20
    • 0030047790 scopus 로고    scopus 로고
    • Gene therapy for metastatic malignant melanoma: Evaluation of tolerance to intratumoral injection of cells producing recombinant retroviruses carrying the herpes simplex virus type 1 thymidine kinase gene, to be followed by ganciclovir administration
    • Klatzmann D. Gene therapy for metastatic malignant melanoma: evaluation of tolerance to intratumoral injection of cells producing recombinant retroviruses carrying the herpes simplex virus type 1 thymidine kinase gene, to be followed by ganciclovir administration. Hum Gene Ther 1996; 7: 255-267.
    • (1996) Hum Gene Ther , vol.7 , pp. 255-267
    • Klatzmann, D.1
  • 21
    • 0030007803 scopus 로고    scopus 로고
    • In vivo analysis of the 'bystander effect': A cytokine cascade
    • Ramesh R et al. In vivo analysis of the 'bystander effect': a cytokine cascade. Exp Hematol 1996; 24: 829-838.
    • (1996) Exp Hematol , vol.24 , pp. 829-838
    • Ramesh, R.1
  • 22
    • 0031953510 scopus 로고    scopus 로고
    • Intercellular delivery of functional p53 by the herpes virus protein VP22
    • Phelan A, Elliott G, O'Hare P. Intercellular delivery of functional p53 by the herpes virus protein VP22. Nat Biotechnol 1998; 16: 440-443.
    • (1998) Nat Biotechnol , vol.16 , pp. 440-443
    • Phelan, A.1    Elliott, G.2    O'Hare, P.3
  • 23
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • Miller AD, Rosman GJ. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989; 7: 980-990.
    • (1989) Biotechniques , vol.7 , pp. 980-990
    • Miller, A.D.1    Rosman, G.J.2
  • 24
    • 0027236954 scopus 로고
    • Production of high-liter helper-free retroviruses by transient transfection
    • Pear WS, Nolan GP, Scott ML, Baltimore MA. Production of high-liter helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 1993; 90: 8392-6.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, M.A.4
  • 25
    • 0029160083 scopus 로고
    • A versatile vector for gene and oligonucleotide transfer into cells in culture and in invo: Polyethylenimine
    • Boussif O et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in invo: polyethylenimine. Proc Natl Acnd Sci USA 1995; 92: 7297-7301.
    • (1995) Proc Natl Acnd Sci USA , vol.92 , pp. 7297-7301
    • Boussif, O.1
  • 26
    • 0020065752 scopus 로고
    • Comparison of thymidine kinase activities induced in cells productively infected with herpes virus saimiri and herpes simplex virus
    • Honess RW, O'Hare P, Young D. Comparison of thymidine kinase activities induced in cells productively infected with herpes virus saimiri and herpes simplex virus. J Gen Virol 1982; 58: 237-249.
    • (1982) J Gen Virol , vol.58 , pp. 237-249
    • Honess, R.W.1    O'Hare, P.2    Young, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.