Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3525-3529

  Black, Margaret E ^a,b   Newcomb, Terry G ^a   Wilson, Heather Marie P ^a   Loeb, Lawrence A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b Darwin Molecular Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; GANCICLOVIR; NUCLEOSIDE ANALOG; THYMIDINE KINASE; VIRUS ENZYME;

ANIMAL CELL; ARTICLE; CANCER THERAPY; CONTROLLED STUDY; DRUG SENSITIVITY; ESCHERICHIA COLI; GENE THERAPY; HERPES SIMPLEX VIRUS 1; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PRIORITY JOURNAL;

ACYCLOVIR; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; DNA; DRUG RESISTANCE, MICROBIAL; ESCHERICHIA COLI; GANCICLOVIR; GENE THERAPY; HERPESVIRUS 1, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; THYMIDINE KINASE; TRANSFECTION;

EID: 0029883624     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3525     Document Type: Article

References (31)

1. Gentry, G. L. (1992) Pharmacol. Ther. 54, 319-355.
2. Boehme, R. E. (1984) J. Biol. Chem. 259, 12346-12349.
3. Miller, W. H. & Miller, R. L. (1980) J. Biol. Chem. 255, 7204-7207.
4. Reardon, J. E. (1989) J. Biol. Chem. 264, 19039-19044.
5. Furman, P. A., St. Clair, M. H. & Spector, T. (1984) J. Biol. Chem. 259, 9575-9579.
6. Culver, K. W., Ram, Z., Wallbridge, S., Ishii, H., Oldfield, E. H. & Blaese, R. M. (1992) Science 256, 1550-1552.
7. Ram, Z., Culver, K. W., Wallbridge, S., Blaese, R. M. & Oldfield, E. H. (1993) Cancer Res. 53, 83-88.
8. Chen, S.-H., Shine, H. D., Goodman, J. C., Grossman, R. G. & Woo, S. L. C. (1994) Proc. Natl. Acad. Sci. USA 91, 3054-3057.
9. O'Malley, B. W., Jr., Chen, S.-H., Schwartz, M. R. & Woo, S. L. C. (1995) Cancer Res. 55, 1080-1085.
10. Chambers, R., Gillespie, G. Y., Soroceanu, L., Andreansky, S., Chatterjee, S., Chou, J., Roizman, B. & Whitley, R. J. (1995) Proc. Natl. Acad. Sci. USA 92, 1411-1415.
11. Takamiya, Y., Short, M. P., Ezzeddine, Z. D., Moolten, F. L., Breakefield, X. O. & Martuza, R. L. (1992) J. Neurosci. Res. 33, 493-503.
12. Vile, R. G. & Hart, I. R. (1993) Cancer Res. 53, 3860-3864.
13. Caruso, M., Partis, Y., Gagandeep, S., Houssin, D., Salzmann, J.-L. & Klatzmann, D. (1993) Proc. Natl. Acad. Sci. USA 90, 7024-7028.
14. Oldfield, E. H., Ram, Z., Culver, K. W., Blaese, R. M. & DeVroom, H. (1993) Hum. Gene Ther. 4, 39-69.
15. Culver, K. W., Van Gilder, J., Link, C. J., Carlstrom, T., Buroker, T., Yuh, W., Koch, K., Schabold, K., Doornbas, S. & Wetjen, B. (1994) Hum. Gene Ther. 5, 343-379.
16. Raffel, C., Culver, K., Kohn, D., Nelson, M., Siegel, S., Gillis, F., Link, C. J. & Villablanca, J. (1994) Hum. Gene Ther. 5, 863-890.
17. Munir, K. M., French, D. C., Dube, D. K. & Loeb, L. A. (1994) Prot. Eng. 7, 83-89.
18. Balzarini, J., Bohman, C. & De Clerq, E. (1993) J. Biol. Chem. 268, 6332-6337.
19. Field, A. K., Davies, M. E., DeWitt, C., Perry, H. C., Liou, R., Germershausen, J., Karkas, J. D., Ashton, W. T., Johnston, D. B. S. & Tolman, R. L. (1983) Proc. Natl. Acad. Sci. USA 80, 4139-4143.
20. Summers, W. C. & Raskin, P. (1993) J. Bacteriol. 175, 6049-6051.
21. Black, M. E. & Hruby, D. E. (1990) J. Biol. Chem. 265, 17584-17594.
22. Black, M. E. & Loeb, L. A. (1993) Biochemistry 32, 11618-11626.
23. Munir, K. M., French, D. C., Dube, D. K. & Loeb, L. A. (1992) J. Biol. Chem. 267, 6584-6589.
24. Duhe, D. K., Parker, J. D., French, D. C., Cahill, D. S., Dube, S., Horwitz, M. S. Z., Munir, K. M. & Loeb, L. A. (1991) Biochemistry 30, 11760-11767.
25. MacGregor, G. R. & Caskey, C. T. (1989) Nucleic Acids Res. 17, 2365.
26. Chen, C. & Okayama, H. (1987) Mol. Cell. Biol. 7, 2745-2752.
27. Southern, P. J. & Berg, P. (1982) J. Mol. Appl. Genet. 1, 327-341.
28. Balasubramaniam, N. K., Veerisetty, V. & Gentry, G. A. (1990) J. Gen. Virol. 71, 2979-2987.
29. Mildvan, A. S., Weber, D. J. & Kuliopulos, A. (1992) Arch. Biochem. Biophys. 294, 327-340.
30. Wild, K., Bohner, T., Aubry, A., Folkers, G. & Schultz, G. E. (1995) FEBS Lett. 368, 289-292.
31. Brown, D. G., Visse, R., Sandhu, G., Davies, A., Rizkallah, P. J., Melitz, C., Summers, W. C. & Sanderson, M. R. (1995) Nature Struct. Biol. 2, 876-881.