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Volumn 1, Issue 2, 2001, Pages 141-153

Thymidine phosphorylase: A two-face janus in anticancer chemotherapy

(2)  Pocher, F a   Spadari, S a  

a CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; ENDOTHELIAL CELL GROWTH FACTOR; ENZYME INHIBITOR; THYMIDINE PHOSPHORYLASE;

EID: 0035427998     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568009013334232     Document Type: Article
Times cited : (73)

References (90)
  • 2
    • 0029150237 scopus 로고
    • The Influence of Angiogenesis Research on Management of Patients with Breast Cancer
    • Folkman, J. The Influence of Angiogenesis Research on Management of Patients with Breast Cancer. Breast Cancer Res. Treat. 1995, 36, 109-118.
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 109-118
    • Folkman, J.1
  • 3
    • 0033650988 scopus 로고    scopus 로고
    • L. K. New Paradigms for the Treatment of Cancer: The Role of AntiAngiogenesis Agents
    • Cherrington, J. M; Strawn, L. M.; Shawver, L. K. New Paradigms for the Treatment of Cancer: The Role of AntiAngiogenesis Agents. Adv. Cancer Res. 2000, 79, 1-38.
    • (2000) Adv. Cancer Res. , vol.79 , pp. 1-38
    • Cherrington, J.M.1    Strawn, L.M.2    Shawver3
  • 4
    • 85013312416 scopus 로고
    • Tumor Angiogenesis: Therapeutic Implications
    • Folkman, J. Tumor Angiogenesis: Therapeutic Implications. N. Engl. J. Med. 1971,255, 1182-1186.
    • (1971) N. Engl. J. Med. , vol.255 , pp. 1182-1186
    • Folkman, J.1
  • 5
    • 0041440927 scopus 로고    scopus 로고
    • Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis
    • Seghezzi, G.; Patel, S.; Ren, C. J.; Gualandris, A.; Pintucci, G.; Robbins, E. S.; Shapiro, R. L.; Galloway, A. C.; Rifkin, D. B.; Mignatti, P. Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis. J. Cell. Biol. 1998, 29, 1659-1673.
    • (1998) J. Cell. Biol. , vol.29 , pp. 1659-1673
    • Seghezzi, G.1    Patel, S.2    Ren, C.J.3    Gualandris, A.4    Pintucci, G.5    Robbins, E.S.6    Shapiro, R.L.7    Galloway, A.C.8    Rifkin, D.B.9    Mignatti, P.10
  • 6
    • 0030851764 scopus 로고    scopus 로고
    • Signaling Vascular Morphogenesis and Maintenance
    • Hanahan, D. Signaling Vascular Morphogenesis and Maintenance. Science 1997, 277, 48-50.
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 7
    • 0023244025 scopus 로고
    • Purification and Properties of an Endothelial Cell Growth Factor from Human Platelets
    • Miyazono, K.; Okabe, T.; Urabe, A.; Takaku, F.; Heldin, C.-H. Purification and Properties of an Endothelial Cell Growth Factor from Human Platelets. J. Biol. Chem. 1987,262, 4098-4103.
    • (1987) J. Biol. Chem. , vol.262 , pp. 4098-4103
    • Miyazono, K.1    Okabe, T.2    Urabe, A.3    Takaku, F.4    Heldin, C.-H.5
  • 9
    • 0030636257 scopus 로고    scopus 로고
    • Angiogenesis and Angiogenesis Inhibition: An Overview
    • Folkman, J. Angiogenesis and Angiogenesis Inhibition: An Overview. EXS 1997, 79, 1-8.
    • (1997) EXS , vol.79 , pp. 1-8
    • Folkman, J.1
  • 12
    • 0024516772 scopus 로고
    • High-Yield Purification of Platelet-Derived Endothelial Cell Growth Factor: Structural Characterization and Establishment of a Specific Antiserum
    • Miyazono, K.; Heldin, C. H. High-Yield Purification of Platelet-Derived Endothelial Cell Growth Factor: Structural Characterization and Establishment of a Specific Antiserum. Biochemistry 1989,25, 1704-1710.
    • (1989) Biochemistry , vol.25 , pp. 1704-1710
    • Miyazono, K.1    Heldin, C.H.2
  • 15
    • 0027138218 scopus 로고
    • Crystallization and X-Ray Diffraction of Recombinant Platelet-Derived Endothelial Cell Growth Factor
    • Spraggon, G.; Stuart, D.; Ponting, C.; Finnis, C.; Sleep, D.; Jones, Y. Crystallization And X-Ray Diffraction of Recombinant Platelet-Derived Endothelial Cell Growth Factor. J. Mol. Biol. 1993, 234, 879-880.
    • (1993) J. Mol. Biol. , vol.234 , pp. 879-880
    • Spraggon, G.1    Stuart, D.2    Ponting, C.3    Finnis, C.4    Sleep, D.5    Jones, Y.6
  • 17
    • 0026690144 scopus 로고
    • Expression of PlateletDerived Endothelial Cell Growth Factor in Escherichia Coli and Confirmation of its Phosphorylase Activity
    • Moghaddam, A.; Bicknell, R. Expression of PlateletDerived Endothelial Cell Growth Factor in Escherichia Coli and Confirmation of its Phosphorylase Activity. Biochemistry 1992,31, 12141-12146.
    • (1992) Biochemistry , vol.31 , pp. 12141-12146
    • Moghaddam, A.1    Bicknell, R.2
  • 18
    • 0027530691 scopus 로고
    • Thymidine Phosphorylase Activity of Platelet-Derived Endothelial Cell Growth Factor is Responsible for Endothelial Cell Mitogenicity
    • Finnis, C.; Dodsworth, N.; Pollitt, C. E.; Sleep, D. Thymidine Phosphorylase Activity of Platelet-Derived Endothelial Cell Growth Factor is Responsible for Endothelial Cell Mitogenicity. Enr. J. Biochem. 1993, 2/2, 201-210.
    • (1993) Enr. J. Biochem. , vol.2 , pp. 201-210
    • Finnis, C.1    Dodsworth, N.2    Pollitt, C.E.3    Sleep, D.4
  • 19
    • 0032529047 scopus 로고    scopus 로고
    • Thymidine Phosphorylase, 2Deoxy-D-Ribose and Angiogenesis
    • Brown, N. S.; Bicknell, R. Thymidine Phosphorylase, 2Deoxy-D-Ribose and Angiogenesis. Biochem. J. 1998, 334, 1-8.
    • (1998) Biochem. J. , vol.334 , pp. 1-8
    • Brown, N.S.1    Bicknell, R.2
  • 20
    • 0026012529 scopus 로고
    • Platelet-Derived Endothelial Cell Growth Factor: Structure and Function
    • Miyazono, K.; Takaku, F. Platelet-Derived Endothelial Cell Growth Factor: Structure and Function. Jpn. Cire. J. 1991,55, 1022-1026.
    • (1991) Jpn. Cire. J. , vol.55 , pp. 1022-1026
    • Miyazono, K.1    Takaku, F.2
  • 21
    • 77049164570 scopus 로고
    • The Enzymatic Synthesis of Nucleosides. Thymidine Phosphorylase in Mammalian Tissue
    • Friedkin, M.; Roberts, D. The Enzymatic Synthesis of Nucleosides. Thymidine Phosphorylase in Mammalian Tissue. J. Biol. Chem. 1953, 207, 245-256.
    • (1953) J. Biol. Chem. , vol.207 , pp. 245-256
    • Friedkin, M.1    Roberts, D.2
  • 23
    • 0028296454 scopus 로고
    • DNA Replication and Chemotherapy
    • Hübscher, U.; Spadari, S. DNA Replication and Chemotherapy. Physiol. Rev. 1994, 74, 259-304.
    • (1994) Physiol. Rev. , vol.74 , pp. 259-304
    • Hübscher, U.1    Spadari, S.2
  • 24
    • 0019404119 scopus 로고
    • Catabolism of Thymidine in Human Blood Platelets. Purification and Properties of Thymidine Phosphorylase
    • Desgranges, C.; Razaka, G.; Rabaud, M.; Bricaud, H. Catabolism of Thymidine in Human Blood Platelets. Purification and Properties of Thymidine Phosphorylase. Biochim. Biophys. Ada 1981, 054, 211218.
    • (1981) Biochim. Biophys. Ada , vol.54 , pp. 211-218
    • Desgranges, C.1    Razaka, G.2    Rabaud, M.3    Bricaud, H.4
  • 25
    • 0019984646 scopus 로고
    • Biochemical Basis for the Differential Sensitivity of Human T- And B-Lymphocyte Lines to 5-FIuorouracil
    • Piper, A. A.; Fox, R. M. Biochemical Basis for the Differential Sensitivity of Human T- and B-Lymphocyte Lines to 5-FIuorouracil. Cancer Res. 1982,42, 37533760.
    • (1982) Cancer Res. , vol.42 , pp. 3753-3760
    • Piper, A.A.1    Fox, R.M.2
  • 26
    • 0021019292 scopus 로고
    • Phosphorolysis of (E)-5-(2Bromovinyl)-2'-Deoxyuridine (BVDU) and other 5-Substituted-2'-Deoxyuridines by Purified Human Thymidine Phosphorylase and Intact Blood Platelets
    • Desgranges, C.; Razaka, G.; Rabaud, M.; Bricaud, H.; Balzarini, J.; De Clercq, E. Phosphorolysis Of (E)-5-(2Bromovinyl)-2'-Deoxyuridine (BVDU) and other 5-Substituted-2'-Deoxyuridines by Purified Human Thymidine Phosphorylase and Intact Blood Platelets. Biochem. Pharmacol. 1983, 32, 3583-3590.
    • (1983) Biochem. Pharmacol. , vol.32 , pp. 3583-3590
    • Desgranges, C.1    Razaka, G.2    Rabaud, M.3    Bricaud, H.4    Balzarini, J.5    De Clercq, E.6
  • 28
    • 0031822118 scopus 로고    scopus 로고
    • Molecular Basis for the Antiviral and Anticancer Activities of Unnatural L-Nucleosides
    • Spadari, S.; Maga, G.; Verri, A.; Focher, F. Molecular Basis for the Antiviral and Anticancer Activities of Unnatural L-Nucleosides. Exp. Opin. Invest. Drugs 1998, 7. 1285-1300.
    • (1998) Exp. Opin. Invest. Drugs , vol.7 , pp. 1285-1300
    • Spadari, S.1    Maga, G.2    Verri, A.3    Focher, F.4
  • 29
    • 0029036828 scopus 로고
    • 5-Iodo-2'-Deoxy-L-Uridine (L-IDU) and (E)-5-(2-Bromovinyl)2'-deoxy-L-uridine (L-BVDU): Selective Phosphorylation by Herpes Simplex Virus Type 1 Thymidine Kinase, Antiherpetic Activity and Cytotoxicity Studies
    • Spadari, S.; Ciarrocchi, G.; Focher, F.; Verri, A.; Maga, G.; Arcamone, F.; lafrate, E.; Manzini, S.; Garbesi, A.; Tondelli, L. 5-Iodo-2'-Deoxy-L-Uridine (L-IDU) and (E)-5-(2-Bromovinyl)2'-deoxy-L-uridine (L-BVDU): Selective Phosphorylation by Herpes Simplex Virus Type 1 Thymidine Kinase, Antiherpetic Activity and Cytotoxicity Studies. Mol. Pharmacol. 1995, 47, 12311238.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1231-1238
    • Spadari, S.1    Ciarrocchi, G.2    Focher, F.3    Verri, A.4    Maga, G.5    Arcamone, F.6    Lafrate, E.7    Manzini, S.8    Garbesi, A.9    Tondelli, L.10
  • 30
    • 0032516763 scopus 로고    scopus 로고
    • Structural and Theoretical Studies Suggest Domain Movement Produces an Active Conformation of Thymidine Phosphorylase
    • Pugmire, M. J.; Cook, W. J.; Jasanoff, A.; Walter, M. R.; Ealick, S. E. Structural and Theoretical Studies Suggest Domain Movement Produces an Active Conformation of Thymidine Phosphorylase. J. Mol. Biol. 1998,281, 285299.
    • (1998) J. Mol. Biol. , vol.281 , pp. 285-299
    • Pugmire, M.J.1    Cook, W.J.2    Jasanoff, A.3    Walter, M.R.4    Ealick, S.E.5
  • 32
    • 0019965353 scopus 로고
    • The Human Blood Platelet: A Cellular Model to Study the Degradation of Thymidine and its Inhibition
    • Desgranges, C.; Razaka, G.; Rabaud, M.; Picard, P.; Dupuch, F.; Bricaud, H. The Human Blood Platelet: A Cellular Model to Study the Degradation of Thymidine and its Inhibition. Biochem. Pharmacol. 1982, 17, 2755-2759.
    • (1982) Biochem. Pharmacol. , vol.17 , pp. 2755-2759
    • Desgranges, C.1    Razaka, G.2    Rabaud, M.3    Picard, P.4    Dupuch, F.5    Bricaud, H.6
  • 33
    • 0025459566 scopus 로고
    • Localization of Platelet-Derived Endothelial Cell Growth Factor in Human Placenta and Purification of an Alternatively Processed Form
    • Usuki, K.; Norberg., L.; Larsson, E.; Miyazono, K.; Hellman, U. W., C.; Rubin, K.; Heldin, C.-H. Localization of Platelet-Derived Endothelial Cell Growth Factor in Human Placenta and Purification of an Alternatively Processed Form. Cell Regvl. 1990, 577596.
    • (1990) Cell Regvl. , pp. 577-596
    • Usuki, K.1    Norberg, L.2    Larsson, E.3    Miyazono, K.4    Hellman, U.W.C.5    Rubin, K.6    Heldin, C.-H.7
  • 34
    • 0025214992 scopus 로고    scopus 로고
    • Purification and Tissue Distribution of Human Thymidine Phosphorylase: High Espression in Lymphocytes, Reticulocytes and Tumors
    • Yoshimura, A.; Kuwazuru, Y.; Furukawa, T.; Yoshida, H.; Yamada, K.; Akiyama, S. Purification and Tissue Distribution of Human Thymidine Phosphorylase: High Espression in Lymphocytes, Reticulocytes and Tumors. Biochim. Biophys. Acta l990, 1034, 107-113.
    • Biochim. Biophys. Acta , vol.1034 , pp. 107-113
    • Yoshimura, A.1    Kuwazuru, Y.2    Furukawa, T.3    Yoshida, H.4    Yamada, K.5    Akiyama, S.6
  • 35
    • 0028961523 scopus 로고
    • Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer
    • O'Brien, T.; Cranston, D.; Fuggle, S.; Biçknell, R.; Harris, A. L. Different Angiogenic Pathways Characterize Superficial and Invasive Bladder Cancer. Cancer Res. 1995, 55, 510-513.
    • (1995) Cancer Res. , vol.55 , pp. 510-513
    • O'Brien, T.1    Cranston, D.2    Fuggle, S.3    Biçknell, R.4    Harris, A.L.5
  • 37
    • 0032146088 scopus 로고    scopus 로고
    • Expression of two Angiogenic Factors, Vascular Endothelial Growth Factor and PlateletDerived Endothelial Cell Growth Factor in Human Pancreatic Cancer, and its Relationship to Angiogenesis
    • Fujimoto, K.; Hosotani, R.; Wada, M.; Lee, J. U.; Koshiba, T.; Miyamoto, Y.; Tsuji, S.; Nakajima, S.; Doi, R.; Imamura, M. Expression of two Angiogenic Factors, Vascular Endothelial Growth Factor and PlateletDerived Endothelial Cell Growth Factor in Human Pancreatic Cancer, and its Relationship to Angiogenesis. Etir. J. Cancer 1998, 34, 1439-1447.
    • (1998) Etir. J. Cancer , vol.34 , pp. 1439-1447
    • Fujimoto, K.1    Hosotani, R.2    Wada, M.3    Lee, J.U.4    Koshiba, T.5    Miyamoto, Y.6    Tsuji, S.7    Nakajima, S.8    Doi, R.9    Imamura, M.10
  • 38
    • 0030679665 scopus 로고    scopus 로고
    • Combined Analysis of Vascular Endothelial Growth Factor and PlateletDerived Endothelial Cell Growth Factor Expression in Gastric Carcinoma
    • Maeda, K.; Kang, S. M.; Ogawa, M.; Sawada, T.; Nakata, B.; Kato, Y.; Chung, Y. S.; Sowa, M. Combined Analysis of Vascular Endothelial Growth Factor and PlateletDerived Endothelial Cell Growth Factor Expression in Gastric Carcinoma. Int. J. Cancer 1997, 74, 545-550.
    • (1997) Int. J. Cancer , vol.74 , pp. 545-550
    • Maeda, K.1    Kang, S.M.2    Ogawa, M.3    Sawada, T.4    Nakata, B.5    Kato, Y.6    Chung, Y.S.7    Sowa, M.8
  • 39
    • 0031203910 scopus 로고    scopus 로고
    • Correlation between Expression of Platelt-Derived Endothelial Cell Growth Factor (Thymidine Phosphorylase) and Microvessel Density in Early-Stage Human Colon Carcinomas
    • Saeki, T.; Tanada, M.; Takashima, S.; Saeki, H.; Takiyama, W.; Nishimoto, N.; Moriwaki, S. Correlation Between Expression of Platelt-Derived Endothelial Cell Growth Factor (Thymidine Phosphorylase) and Microvessel Density in Early-Stage Human Colon Carcinomas. Jpn. J. Clin. Oncol. 1997, 27, 227-230.
    • (1997) Jpn. J. Clin. Oncol. , vol.27 , pp. 227-230
    • Saeki, T.1    Tanada, M.2    Takashima, S.3    Saeki, H.4    Takiyama, W.5    Nishimoto, N.6    Moriwaki, S.7
  • 40
    • 0030869384 scopus 로고    scopus 로고
    • Expression of Thymidine Phosphorylase in Uterine Sarcoma and Uterine Leiomyoma: Association with Microvessel Density and Doppler Blood Flow Analysis
    • Hâta, K.; Hâta, T.; lida, K.; Miyazaki, K. Expression of Thymidine Phosphorylase in Uterine Sarcoma and Uterine Leiomyoma: Association with Microvessel Density and Doppler Blood Flow Analysis. Ultrasound Obstet. Gynecol. 1997, 10, 54-58.
    • (1997) Ultrasound Obstet. Gynecol. , vol.10 , pp. 54-58
    • Hâta, K.1    Hâta, T.2    Lida, K.3    Miyazaki, K.4
  • 42
    • 0031038068 scopus 로고    scopus 로고
    • Expression of the Angiogenic Factors Vascular Endothelial Cell Growth Factor, Acidic and Basic Fibroblast Growth Factor Beta-1, Platelet-Derived Endothelial Cell Growth Factor, Placenta Growth Factor, and Pleiotrophin in Human Primary Breast Cancer and its Relation to Angiogenesis
    • Reif, M.; LeJeune, S.; Scott, P. A.; Fox, S.; Smith, K.; Moghaddam, A.; Whitehouse, R.; Bicknell, R.; Harris, A. L. Expression of the Angiogenic Factors Vascular Endothelial Cell Growth Factor, Acidic and Basic Fibroblast Growth Factor Beta-1, Platelet-Derived Endothelial Cell Growth Factor, Placenta Growth Factor, and Pleiotrophin in Human Primary Breast Cancer and its Relation to Angiogenesis. Cancer Res. 1997, 57, 963-969.
    • (1997) Cancer Res. , vol.57 , pp. 963-969
    • Reif, M.1    Lejeune, S.2    Scott, P.A.3    Fox, S.4    Smith, K.5    Moghaddam, A.6    Whitehouse, R.7    Bicknell, R.8    Harris, A.L.9
  • 44
    • 0030027519 scopus 로고    scopus 로고
    • The Angiogenic Factor Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase is Up-Regulated in Breast Cancer Epithelium and Endothelium
    • Fox, S. B.; Westwood, M.; Moghaddam, A.; Comley, M.; Turley, H.; Whitehouse, R. M.; Bicknell, R.; Gatter, K. C.; Harris, A. L. The Angiogenic Factor Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase is Up-Regulated in Breast Cancer Epithelium and Endothelium. Br. J. Cancer 1996, 73, 275-280.
    • (1996) Br. J. Cancer , vol.73 , pp. 275-280
    • Fox, S.B.1    Westwood, M.2    Moghaddam, A.3    Comley, M.4    Turley, H.5    Whitehouse, R.M.6    Bicknell, R.7    Gatter, K.C.8    Harris, A.L.9
  • 45
    • 14444267310 scopus 로고    scopus 로고
    • The Expression of Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor is Correlated to Angiogenesis in Breast Cancer
    • Yonenaga, F.; Takasaki, T.; Ohi, Y.; Sagara, Y.; Akiba, S.; Yoshinaka, H.; Aikou, T.; Miyadera, K.; Akiyama, S.; Yoshida, H. The Expression of Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor is Correlated to Angiogenesis in Breast Cancer. Pathol. Int. 1998, 48, 850-856.
    • (1998) Pathol. Int. , vol.48 , pp. 850-856
    • Yonenaga, F.1    Takasaki, T.2    Ohi, Y.3    Sagara, Y.4    Akiba, S.5    Yoshinaka, H.6    Aikou, T.7    Miyadera, K.8    Akiyama, S.9    Yoshida, H.10
  • 46
    • 0031993150 scopus 로고    scopus 로고
    • Stromal Angiogenesis in Human Glioma: A Role of PlateletDerived Endothelial Cell Growth Factor
    • Nakayama, Y.; Sueishi K; Oka K; Kono S; M., T. Stromal Angiogenesis in Human Glioma: A Role of PlateletDerived Endothelial Cell Growth Factor. Surg. Neural. 1998,49, 181-188.
    • (1998) Surg. Neural. , vol.49 , pp. 181-188
    • Nakayama, Y.1    Sueishi, K.2    Oka, K.3    Kono, S.4
  • 48
    • 0029790296 scopus 로고    scopus 로고
    • Platelet-Derived Endothelial Cell Growth Factor in Human Colon Cancer Angiogenesis: Role of Infiltrating Cells
    • Takahashi, Y.; Bucana, C D.; Liu, W.; Yoneda, J.; Kitadai, Y.; Cleary, K. R.; Ellis, L. M. Platelet-Derived Endothelial Cell Growth Factor in Human Colon Cancer Angiogenesis: Role of Infiltrating Cells. J. Natl. Cancer Inst.1996,88, 1146-1151.
    • (1996) J. Natl. Cancer Inst. , vol.88 , pp. 1146-1151
    • Takahashi, Y.1    Bucana, C.D.2    Liu, W.3    Yoneda, J.4    Kitadai, Y.5    Cleary, K.R.6    Ellis, L.M.7
  • 50
    • 0031449585 scopus 로고    scopus 로고
    • Overexpression of the Angiogenic Factor PlateletDerived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Psoriatic Epidermis
    • Creamer, D.; Jaggar, R.; Alien, M.; Bicknell, R.; Barker, J. Overexpression of the Angiogenic Factor PlateletDerived Endothelial Cell Growth Factor/Thymidine Phosphorylase in Psoriatic Epidermis. Br. J. Dermatol. 1997,137, 851-855.
    • (1997) Br. J. Dermatol. , vol.137 , pp. 851-855
    • Creamer, D.1    Jaggar, R.2    Alien, M.3    Bicknell, R.4    Barker, J.5
  • 51
    • 0030815830 scopus 로고    scopus 로고
    • Evidence for Participation of Gliostatin/Platelet-Derived Endothelial Cell Growth Factor in Gastric Ulcer Healing
    • Kasugai, K.; Joh, T.; Kataoka, H.; Sasaki, M.; Tada, T.; Asai, K.;'Kato, T.; Itoh, M. Evidence For Participation of Gliostatin/Platelet-Derived Endothelial Cell Growth Factor in Gastric Ulcer Healing. Life Sei. 1997,61, 1899-1906.
    • (1997) Life Sei. , vol.61 , pp. 1899-1906
    • Kasugai, K.1    Joh, T.2    Kataoka, H.3    Sasaki, M.4    Tada, T.5    Asai, K.6    Kato, T.7    Itoh, M.8
  • 53
    • 0028017433 scopus 로고
    • Structural Properties of 3.0 kb and 3.2 kb Transcripts Encoding Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in A431 Cells
    • Usuki, K.; Gonez, L. J.; Wernstedt, C.; Moren, A.; Miyazono, K.; Claesson-Welsh, L.; Heldin, C. H. Structural Properties of 3.0 kb and 3.2 kb Transcripts Encoding Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase in A431 Cells. Biochim. Biophys. Acta 1994, 1222, 411-414.
    • (1994) Biochim. Biophys. Acta , vol.1222 , pp. 411-414
    • Usuki, K.1    Gonez, L.J.2    Wernstedt, C.3    Moren, A.4    Miyazono, K.5    Claesson-Welsh, L.6    Heldin, C.H.7
  • 54
    • 0030753430 scopus 로고    scopus 로고
    • Spl Recognition Sites in the Proximal Promoter of the Human Vascular Endothelial Growth Factor Gene are Essential Forplatelet-Derived Growth Factor-Induced Gene Expression
    • Finkenzeller, G.; Sparacio, A.; Technau, A.; Marme, D.; Siemeister, G. Spl Recognition Sites in The Proximal Promoter of The Human Vascular Endothelial Growth Factor Gene are Essential Forplatelet-Derived Growth Factor-Induced Gene Expression. Oncogene 1997, 15, 669-676.
    • (1997) Oncogene , vol.15 , pp. 669-676
    • Finkenzeller, G.1    Sparacio, A.2    Technau, A.3    Marme, D.4    Siemeister, G.5
  • 55
    • 0035863390 scopus 로고    scopus 로고
    • Interferon Gamma-Dependent Induction of Thymidine Phosphorylase/Platelet-Derived Endothelial Growth Factor through Gamma-Activated SequenceLike Element in Human Macrophages
    • Goto, H.; Kohno, K.; Sone, S.; Akiyama, S.; Kuwano, M.; Ono, M. Interferon Gamma-Dependent Induction of Thymidine Phosphorylase/Platelet-Derived Endothelial Growth Factor Through Gamma-Activated SequenceLike Element in Human Macrophages. Cancer Res. 2001, 61, 469-473.
    • (2001) Cancer Res. , vol.61 , pp. 469-473
    • Goto, H.1    Kohno, K.2    Sone, S.3    Akiyama, S.4    Kuwano, M.5    Ono, M.6
  • 56
    • 0029102247 scopus 로고
    • 5-Ethoxy-2'-Deoxyuridine, a Novel Substrate for Thymidine Phosphorylase, Potentiates the Antitumor Activity of 5-Fluorouracil when Used in Combination with Interferon, an Inducer of Thymidine Phosphorylase Expression
    • Schwanz, E. L.; Baptiste, N.; Megati, S.; VVadler, S.; Otter, B. A. 5-Ethoxy-2'-Deoxyuridine, a Novel Substrate for Thymidine Phosphorylase, Potentiates the Antitumor Activity of 5-Fluorouracil when Used in Combination with Interferon, an Inducer of Thymidine Phosphorylase Expression. Cancer Res. 1995, 55, 35433550.
    • (1995) Cancer Res. , vol.55 , pp. 3543-3550
    • Schwanz, E.L.1    Baptiste, N.2    Megati, S.3    Vvadler, S.4    Otter, B.A.5
  • 57
    • 0030993629 scopus 로고    scopus 로고
    • Interferon Induces Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor Expression in Vivo
    • Makower, D.; Wadler, S.; Haynes, H.; L., S. E. Interferon Induces Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor Expression In Vivo. Clin. Cancer Res. 1997, 3, 923-929.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 923-929
    • Makower, D.1    Wadler, S.2    Haynes, H.L.3
  • 58
    • 0032054223 scopus 로고    scopus 로고
    • Regulation of Expression of Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor in Human Colon Carcinoma Cells
    • Schwanz, E. L.; Wan, E.; Wang, F. S.; Baptiste, N. Regulation Of Expression Of Thymidine Phosphorylase/Platelet-Derived Endothelial Cell Growth Factor in Human Colon Carcinoma Cells. Cancer Res. 1998, 58, 1551-1557.
    • (1998) Cancer Res. , vol.58 , pp. 1551-1557
    • Schwanz, E.L.1    Wan, E.2    Wang, F.S.3    Baptiste, N.4
  • 59
    • 0025836938 scopus 로고
    • Covalent Linkage between Nucleotides and Platelet-Derived Endothelial Cell Growth Factor
    • Usuki, K.; Miyazono, K.; Heldin, C.-H. Covalent Linkage Between Nucleotides and Platelet-Derived Endothelial Cell Growth Factor. J. Biol. Chem. 1991, 266, 20525-20531.
    • (1991) J. Biol. Chem. , vol.266 , pp. 20525-20531
    • Usuki, K.1    Miyazono, K.2    Heldin, C.-H.3
  • 62
    • 0028957177 scopus 로고
    • Role of Thymidine Phosphorylase Activity in the Angiogenic Effect of Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase
    • Miyadera, K.; Sumizawa, T.; Haraguchi, M.; Yoshida, H.; Konstanty, W.; Yamada, Y.; Akiyama, S. Role of Thymidine Phosphorylase Activity in the Angiogenic Effect of Platelet-Derived Endothelial Cell Growth Factor/Thymidine Phosphorylase. Cancer Res. 1995, 55, 1687-1690.
    • (1995) Cancer Res. , vol.55 , pp. 1687-1690
    • Miyadera, K.1    Sumizawa, T.2    Haraguchi, M.3    Yoshida, H.4    Konstanty, W.5    Yamada, Y.6    Akiyama, S.7
  • 65
    • 0033692793 scopus 로고    scopus 로고
    • Thymidine Phosphorylase Induces Carcinoma Cell Oxidative Stress and Promotes Secretion of Angiogenic Factors
    • Brown, N. S.; Jones, A.; Fujiyama, C.; Harris, A. L.; Bicknell, R. Thymidine Phosphorylase Induces Carcinoma Cell Oxidative Stress and Promotes Secretion of Angiogenic Factors. Cancer Res. 2000, 60, 62986302.
    • (2000) Cancer Res. , vol.60 , pp. 6298-6302
    • Brown, N.S.1    Jones, A.2    Fujiyama, C.3    Harris, A.L.4    Bicknell, R.5
  • 66
    • 0025373091 scopus 로고
    • Non Enzymatic Glycosylation, the Maillard Reaction and the Aging Process
    • Monnier, V. M. Non Enzymatic Glycosylation, the Maillard Reaction and the Aging Process. J. Gerontol. 1990, BIOS-Bill.
    • (1990) J. Gerontol.
    • Monnier, V.M.1
  • 68
    • 0029943568 scopus 로고    scopus 로고
    • Plasminogen Activators and Matrix Metalloproteinases in Angiogenesis
    • Mignatti, P.; Rifkin, D. B. Plasminogen Activators and Matrix Metalloproteinases in Angiogenesis. Enzyme Protein 1996, 49, 117-137.
    • (1996) Enzyme Protein , vol.49 , pp. 117-137
    • Mignatti, P.1    Rifkin, D.B.2
  • 70
    • 0022475937 scopus 로고
    • Enzymatic Cleavage of 5-Substituted-2'-Deoxyuridines by Pyrimidine Nucleoside Phosphorylases
    • Veres, Z.; Szabolcs, A.; Szinai, I.; Denes, G.; Jeney, A. Enzymatic Cleavage of 5-Substituted-2'-Deoxyuridines by Pyrimidine Nucleoside Phosphorylases. Biochem. Pharmacol. 1986, 35, 1057-1059.
    • (1986) Biochem. Pharmacol. , vol.35 , pp. 1057-1059
    • Veres, Z.1    Szabolcs, A.2    Szinai, I.3    Denes, G.4    Jeney, A.5
  • 71
    • 0027306127 scopus 로고
    • Differences in Activities and Substrate Specificity of Human and Murine Pyrimidine Nucleoside Phosphorylases: Implications for Chemotherapy with 5Fluoropyrimidines
    • el Kouni, M. H.; el Kouni, M. M.; Naguib, F. N. Differences in Activities and Substrate Specificity of Human and Murine Pyrimidine Nucleoside Phosphorylases: Implications for Chemotherapy with 5Fluoropyrimidines. Cancer Res. 1993, 53, 3687-3693.
    • (1993) Cancer Res. , vol.53 , pp. 3687-3693
    • Kouni, M.H.1    El Kouni, M.M.2    Naguib, F.N.3
  • 72
    • 0027445159 scopus 로고
    • Sensitivity of Human KB Cells Expressing PlateletDerived Endothelial Cell Growth Factor to Pyrimidine Antimetabolites
    • Haraguchi, M.; Furukawa, T.; Sumizawa, T.; Akiyama, S. Sensitivity of Human KB Cells Expressing PlateletDerived Endothelial Cell Growth Factor to Pyrimidine Antimetabolites. Cancer Res. 1993, 53, 5680-5682.
    • (1993) Cancer Res. , vol.53 , pp. 5680-5682
    • Haraguchi, M.1    Furukawa, T.2    Sumizawa, T.3    Akiyama, S.4
  • 73
    • 0027313603 scopus 로고
    • Cytokines Induce Thymidine Phosphorylase Expression in Tumor Cells and Make them more Susceptible to 5'-Deoxy-5fluorouridine
    • Eda, H.; Fujimoto, K.; Watanabe, S.; Ura, M.; Hino, A.; Tanaka, Y.; Wada, K.; Ishitsuka, H. Cytokines Induce Thymidine Phosphorylase Expression in Tumor Cells and Make them More Susceptible to 5'-Deoxy-5fluorouridine. Cancer Chemother. Pharmacol. 1993, 32, 333-338.
    • (1993) Cancer Chemother. Pharmacol. , vol.32 , pp. 333-338
    • Eda, H.1    Fujimoto, K.2    Watanabe, S.3    Ura, M.4    Hino, A.5    Tanaka, Y.6    Wada, K.7    Ishitsuka, H.8
  • 74
    • 0029051690 scopus 로고
    • Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil
    • Schwartz, E. L.; Baptiste, N.; Wadler, S.; Makower, D. Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil. J. Biol. Chem. 1995, 270, 19073-19077.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19073-19077
    • Schwartz, E.L.1    Baptiste, N.2    Wadler, S.3    Makower, D.4
  • 75
    • 0030993629 scopus 로고    scopus 로고
    • Interferon Induces Thymidine Phosphorylase/PlateletDerived Endothelial Cell Growth Factor Expression in Vivo
    • Makower, D.; Wadler, S.; Haynes, H.; Schwartz, E. L. Interferon Induces Thymidine Phosphorylase/PlateletDerived Endothelial Cell Growth Factor Expression In Vivo. Clin. Cancer Res. 1997, 3, 923-929.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 923-929
    • Makower, D.1    Wadler, S.2    Haynes, H.3    Schwartz, E.L.4
  • 76
    • 0033402735 scopus 로고    scopus 로고
    • Interferons as Biomodulators of Fluoropyrimidines in the Treatment of Colorectal Cancer
    • Makower, D.; Wadler, S. Interferons as Biomodulators of Fluoropyrimidines in the Treatment of Colorectal Cancer. Semin. Oncol. 1999,26, 663-671.
    • (1999) Semin. Oncol. , vol.26 , pp. 663-671
    • Makower, D.1    Wadler, S.2
  • 77
    • 0014197030 scopus 로고
    • Inhibition of Thymidine Phosphorylase by 6Aminothymine and Derivatives of 6-Aminouracil
    • Langen, P.; Etzold, G.; Bärwolff, D.; Preusel, B. Inhibition of Thymidine Phosphorylase by 6Aminothymine and Derivatives of 6-Aminouracil. Biochem. Pharmacol. 1967,16, 1833-1837.
    • (1967) Biochem. Pharmacol. , vol.16 , pp. 1833-1837
    • Langen, P.1    Etzold, G.2    Bärwolff, D.3    Preusel, B.4
  • 80
    • 0034729729 scopus 로고    scopus 로고
    • Novel Non-Substrate Inhibitors of Human Thymidine Phosphorylase, a Potential Target for Tumor-Dependent Angiogenesis
    • Focher, F.; Spadari, S.; Ubiali, D.; Pregnolato, M.; Zhi, C.; Gambino, J.; Wright, G. E. Novel Non-Substrate Inhibitors of Human Thymidine Phosphorylase, a Potential Target for Tumor-Dependent Angiogenesis. J. Med. Chem. 2000, 43, 2601-2607.
    • (2000) J. Med. Chem. , vol.43 , pp. 2601-2607
    • Focher, F.1    Spadari, S.2    Ubiali, D.3    Pregnolato, M.4    Zhi, C.5    Gambino, J.6    Wright, G.E.7
  • 81
    • 0034624754 scopus 로고    scopus 로고
    • Design, Synthesis, and Enzymatic Evaluation of Multisubstrate Analogue Inhibitors of Escherichia Coli Thymidine Phosphorylase
    • Esteban-Gamboa, A.; Balzarini, J.; Esnouf, R.; De Clercq, E.; Camarasa, M. J.; Perez-Perez, M. J. Design, Synthesis, and Enzymatic Evaluation of Multisubstrate Analogue Inhibitors of Escherichia Coli Thymidine Phosphorylase. J. Med. Chem.2000,43, 971-983.
    • (2000) J. Med. Chem. , vol.43 , pp. 971-983
    • Esteban-Gamboa, A.1    Balzarini, J.2    Esnouf, R.3    De Clercq, E.4    Camarasa, M.J.5    Perez-Perez, M.J.6
  • 85
    • 0028301915 scopus 로고
    • Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): Clinical, Biochemical, and Genetic Features of an Autosomal Recessive Mitochondrial Disorder
    • Hirano, M.; Silvestri, G.; Blake, D. M.; Lombes, A.; Minetti, C.; Bonilla, E.; Hays, A. P.; Lovelace, R. E.; Butler, I.; Bertorini, T. E. Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE): Clinical, Biochemical, and Genetic Features of an Autosomal Recessive Mitochondrial Disorder. Neurology 1994, 44, 721-727.
    • (1994) Neurology , vol.44 , pp. 721-727
    • Hirano, M.1    Silvestri, G.2    Blake, D.M.3    Lombes, A.4    Minetti, C.5    Bonilla, E.6    Hays, A.P.7    Lovelace, R.E.8    Butler, I.9    Bertorini, T.E.10
  • 87
    • 0033613865 scopus 로고    scopus 로고
    • Thymidine Phosphorylase Gene Mutations in MNGIE, a Human Mitochondrial Disorder
    • Nishino, I.; Spinazzola, A.; Hirano, M. Thymidine Phosphorylase Gene Mutations in MNGIE, a Human Mitochondrial Disorder. Science 1999, 283, 689-692.
    • (1999) Science , vol.283 , pp. 689-692
    • Nishino, I.1    Spinazzola, A.2    Hirano, M.3
  • 90
    • 0033945199 scopus 로고    scopus 로고
    • Defects of Intergenomic Communication: Where do we Stand?
    • Hirano, M.; Vu, T. H. Defects of Intergenomic Communication: Where do we Stand? Brain Pathol. 2000,10, 451-461.
    • (2000) Brain Pathol. , vol.10 , pp. 451-461
    • Hirano, M.1    Vu, T.H.2


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