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Volumn 20, Issue 53, 2001, Pages 7797-7803

Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954

(8) Plumb, Jane A a Bilsland, Alan a Kakani, Rania a Zhao, Jiangqin a Glasspool, Rosalind M a Knox, Richard J b Evans, T R Jeffry a Keith, W Nicol a

a UNIVERSITY OF GLASGOW (United Kingdom)

b Enact Pharma PLC (United Kingdom)

Author keywords

GDEPT; Gene therapy; HTERT; HTR; Nitroreductase; Telomerase

Indexed keywords

5 (1 AZIRIDINYL) 2,4 DINITROBENZAMIDE; GENE PRODUCT; NITROREDUCTASE; PRODRUG; PROTEIN HTR; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CANCER GROWTH; CANCER THERAPY; CONTROLLED STUDY; DNA VECTOR; DRUG ACTIVITY; DRUG TARGETING; ENZYME ACTIVATION; GENE ACTIVITY; GENE EXPRESSION; GENE THERAPY; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SUICIDE GENE; XENOGRAFT;

EID: 0035936001 PISSN: 09509232 EISSN: None Source Type: Journal
DOI: 10.1038/sj.onc.1204954 Document Type: Article

Times cited : (99)

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