Potentiation of cytochrome P450/cyclophosphamide-based cancer gene therapy by coexpression of the P450 reductase gene

Cancer Research

Volumn 57, Issue 21, 1997, Pages 4830-4837

  Chen, Ling ^a,b   Yu, Li J ^a,c   Waxman, David J ^a  

^a Boston University   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHOSPHAMIDE; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; DIPHENYLENEIODONIUM CHLORIDE; FLAVOPROTEIN; METYRAPONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER SURVIVAL; CHEMOSENSITIVITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME ANALYSIS; FEMALE; GENE THERAPY; GENE TRANSFER; GROWTH INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOVIRIDAE; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL COMMUNICATION; CYCLOPHOSPHAMIDE; CYTOCHROME P-450 CYP2B1; FEMALE; GENE THERAPY; GENETIC VECTORS; GLIOSARCOMA; METYRAPONE; NADH, NADPH OXIDOREDUCTASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; NEOPLASM PROTEINS; PRODRUGS; RATS; RATS, INBRED F344; TUMOR CELLS, CULTURED; TUMOR STEM CELL ASSAY;

EID: 0030810198     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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