Enzymology of tirapazamine metabolism: A review

Anti-Cancer Drug Design

Volumn 13, Issue 6, 1998, Pages 541-573

  Patterson, A V ^a   Saunders, M P ^a   Chinje, E C ^a   Patterson, L H ^a   Stratford, I J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Cytotoxicity; Enzymology; Free radical; Hypoxia; One electron bioactivation; Tirapazamine

Indexed keywords

ANTINEOPLASTIC AGENT; OXIDOREDUCTASE; TIRAPAZAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; CELLULAR DISTRIBUTION; DRUG METABOLISM; ENZYME LOCALIZATION; ENZYMOLOGY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SOLID TUMOR; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; CYTOCHROME P-450 ENZYME SYSTEM; CYTOCHROME REDUCTASES; CYTOCHROME-B(5) REDUCTASE; HUMANS; MICROSOMES, LIVER; MITOCHONDRIA, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDOREDUCTASES; TRIAZINES;

EID: 0031656983     PISSN: 02669536     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (178)