Protein misfolding in the endoplasmic reticulum as a conduit to human disease

Nature

Volumn 529, Issue 7586, 2016, Pages 326-335

  Wang, Miao ^a   Kaufman, Randal J ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CYTOKINE; HORMONE; PROTEIN;

CELLS AND CELL COMPONENTS; DISEASE; ETIOLOGY; EUKARYOTE; HOMEOSTASIS; PROTEIN;

CELL DEATH; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL GROWTH; CELL METABOLISM; CELL ORGANELLE; CELL SURVIVAL; DEGENERATIVE DISEASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENETIC DISORDER; HOMEOSTASIS; HUMAN; INFLAMMATION; MALIGNANT NEOPLASTIC DISEASE; METABOLIC DISORDER; MOLECULAR PATHOLOGY; MOLECULARLY TARGETED THERAPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN HOMEOSTASIS; PROTEIN SECRETION; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ANIMAL; CHEMISTRY; DISEASES; METABOLISM; PATHOLOGY;

EUKARYOTA;

ANIMALS; DISEASE; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; HUMANS; MOLECULAR TARGETED THERAPY; PROTEIN FOLDING; PROTEINS; UNFOLDED PROTEIN RESPONSE;

EID: 84955445779     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17041     Document Type: Review

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