Noncanonical binding of BiP ATPase domain to Ire1 and Perk is dissociated by unfolded protein CH1 to initiate ER stress signaling

eLife

Volumn 2015, Issue 4, 2015, Pages

  Carrara, Marta ^a   Prischi, Filippo ^a   Nowak, Piotr R ^a   Kopp, Megan C ^a   Ali, Maruf M U ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; GLUCOSE REGULATED PROTEIN 78; PEPTIDES AND PROTEINS; PERK PROTEIN; PROTEIN IRE1; UNCLASSIFIED DRUG; EIF2AK3 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; MOLECULAR CHAPERONE GRP78; PROTEIN BINDING; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LIGHT SCATTERING; NONCANONICAL BINDING; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; METABOLISM;

EIF-2 KINASE; ENDORIBONUCLEASES; HEAT-SHOCK PROTEINS; HUMANS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; UNFOLDED PROTEIN RESPONSE;

EID: 84964698311     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.03522     Document Type: Article

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