Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes

Journal of Clinical Investigation

Volumn 118, Issue 10, 2008, Pages 3378-3389

  Song, Benbo ^a   Scheuner, Donalyn ^a   Ron, David ^b   Pennathur, Subramaniam ^a   Kaufman, Randal J ^a,c  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL FUNCTION; CELL ISOLATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DIABETES MELLITUS; GLYCEMIC CONTROL; INSULIN RESISTANCE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DIET; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION; INSULIN-SECRETING CELLS; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MUTATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; TRANSCRIPTION FACTOR CHOP;

EID: 55849096988     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI34587     Document Type: Article

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