The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis

Journal of Clinical Investigation

Volumn 115, Issue 2, 2005, Pages 268-281

  Zhang, Kezhong ^a   Wong, Hetty N ^a   Song, Benbo ^a   Miller, Corey N ^a   Scheuner, Donalyn ^a   Kaufman, Randal J ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD45 ANTIGEN; IMMUNOGLOBULIN; LEUKOSIALIN; MESSENGER RNA; PROTEIN IRE1; PROTEIN IRE1ALPHA; PROTEIN KINASE R; PROTEIN SERINE THREONINE KINASE; RAG2 PROTEIN; RIBONUCLEASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; ERN2 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; NUCLEAR PROTEIN; RAG2 PROTEIN, MOUSE; SPLICING ENDONUCLEASE; TRE BINDING PROTEIN; TRE-BINDING PROTEIN; V(D)J RECOMBINATION ACTIVATING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE DIFFERENTIATION; CELL MATURATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FETUS; GENE; GENE REARRANGEMENT; IMMUNOGLOBULIN PRODUCTION; LIVER DEVELOPMENT; LYMPHOPOIESIS; MOUSE; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; RAG2 GENE; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; TRANSLATION REGULATION; UNFOLDED PROTEIN RESPONSE; WESTERN BLOTTING; ANIMAL; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; GENETICS; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; PROTEIN DENATURATION; RNA SPLICING;

ANIMALS; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; DNA-BINDING PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENDORIBONUCLEASES; GENE REARRANGEMENT, B-LYMPHOCYTE; IMMUNOGLOBULINS; LYMPHOPOIESIS; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NUCLEAR PROTEINS; PLASMA CELLS; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, ANTIGEN, B-CELL; RNA SPLICING; SIGNAL TRANSDUCTION;

EID: 14944371187     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200521848     Document Type: Article

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