TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages

Nature Immunology

Volumn 11, Issue 5, 2010, Pages 411-418

  Martinon, Fabio ^a   Chen, Xi ^a   Lee, Ann Hwee ^a,b   Glimcher, Laurie H ^a,b,c  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b Department of Medicine ^*  (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN IRE1; PROTEIN IRE1ALPHA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM STRESS; FRANCISELLA TULARENSIS; HOST RESISTANCE; IMMUNOREGULATION; INNATE IMMUNITY; MACROPHAGE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; TRANSCRIPTION INITIATION;

ANIMALS; CELL LINE; CYTOKINES; DNA-BINDING PROTEINS; ENDORIBONUCLEASES; FRANCISELLA TULARENSIS; IMMUNITY, INNATE; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MYELOID DIFFERENTIATION FACTOR 88; NADPH OXIDASE; PROTEIN SPLICING; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTOR CHOP; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TULAREMIA; TUNICAMYCIN;

EID: 77951290227     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.1857     Document Type: Article

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