Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

Nature Medicine

Volumn 20, Issue 12, 2014, Pages 1417-1426

  Hasnain, Sumaira Z ^a   Borg, Danielle J ^a   Harcourt, Brooke E ^a   Tong, Hui ^a   Sheng, Yonghua H ^a   Ng, Choa Ping ^a   Das, Indrajit ^a   Wang, Ran ^a   Chen, Alice C H ^a   Loudovaris, Thomas ^b   Kay, Thomas W ^b   Thomas, Helen E ^b   Whitehead, Jonathan P ^a   Forbes, Josephine M ^a   Prins, Johannes B ^a   McGuckin, Michael A ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b St Vincent's Research Institute   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 24; INTERLEUKIN 33; PROINSULIN; CYTOKINE; GLUCOSE BLOOD LEVEL; IL33 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; INTERLEUKIN-24; INTERLEUKIN-33, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INFLAMMATION; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SYNTHESIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; METABOLISM; PANCREAS ISLET; SECRETION (PROCESS);

MUS;

ANIMALS; BLOOD GLUCOSE; CYTOKINES; DIABETES MELLITUS, TYPE 2; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTERLEUKIN-23; INTERLEUKINS; ISLETS OF LANGERHANS; MICE; OXIDATIVE STRESS;

EID: 84925581887     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3705     Document Type: Article

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