메뉴 건너뛰기




Volumn 22, Issue 13, 2015, Pages 1111-1129

Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; CALCIUM ION; COMPLEMENT MEMBRANE ATTACK COMPLEX; CRYOPYRIN; DOUBLE STRANDED DNA; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MICRORNA; MITOCHONDRIAL DNA; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; POTASSIUM ION; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; CARRIER PROTEIN; NLRP3 PROTEIN, HUMAN;

EID: 84924034834     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2014.5994     Document Type: Review
Times cited : (697)

References (155)
  • 1
    • 84934313648 scopus 로고    scopus 로고
    • Contribution of guanine nucleotide exchange factor Vav2 to homocysteine- induced NLRP3 inflammasome activation in mouse podocytes
    • Abais JM, Xia M, Boini KM, and Li PL. Contribution of guanine nucleotide exchange factor Vav2 to homocysteine- induced NLRP3 inflammasome activation in mouse podocytes. FASEB J 28: 1063.6, 2014.
    • (2014) FASEB J , vol.28 , pp. 10636
    • Abais, J.M.1    Xia, M.2    Boini, K.M.3    Li, P.L.4
  • 2
    • 84907588640 scopus 로고    scopus 로고
    • Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein during hyperhomocysteinemia
    • Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, and Li PL. Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein during hyperhomocysteinemia. J Biol Chem 289: 27159, 2014.
    • (2014) J Biol Chem , vol.289
    • Abais, J.M.1    Xia, M.2    Li, G.3    Chen, Y.4    Conley, S.M.5    Gehr, T.W.6    Boini, K.M.7    Li, P.L.8
  • 3
    • 84888607647 scopus 로고    scopus 로고
    • Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia
    • Abais JM, Xia M, Li G, Gehr TW, Boini KM, and Li PL. Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia. Free Radic Biol Med 67: 211-220, 2014.
    • (2014) Free Radic Biol Med , vol.67 , pp. 211-220
    • Abais, J.M.1    Xia, M.2    Li, G.3    Gehr, T.W.4    Boini, K.M.5    Li, P.L.6
  • 4
    • 84875730240 scopus 로고    scopus 로고
    • NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia
    • Abais JM, Zhang C, Xia M, Liu Q, Gehr TW, Boini KM, and Li PL. NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal 18: 1537-1548, 2013.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1537-1548
    • Abais, J.M.1    Zhang, C.2    Xia, M.3    Liu, Q.4    Gehr, T.W.5    Boini, K.M.6    Li, P.L.7
  • 6
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, and Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20: 319-325, 2004.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 7
    • 84881344806 scopus 로고    scopus 로고
    • TNF-Alpha may mediate inflammasome activation in the absence of bacterial infection in more than one way
    • Alvarez S, Munoz-Fernandez MA. TNF-Alpha may mediate inflammasome activation in the absence of bacterial infection in more than one way. PLoS One 8: e71477, 2013.
    • (2013) PLoS One , vol.8
    • Alvarez, S.1    Munoz-Fernandez, M.A.2
  • 9
    • 80655144737 scopus 로고    scopus 로고
    • Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly
    • Bae JY and Park HH. Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly. J Biol Chem 286: 39528-39536, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 39528-39536
    • Bae, J.Y.1    Park, H.H.2
  • 11
    • 1642286961 scopus 로고    scopus 로고
    • The role of ROS and RNS in regulating life and death of blood monocytes
    • Baran CP, Zeigler MM, Tridandapani S, and Marsh CB. The role of ROS and RNS in regulating life and death of blood monocytes. Curr Pharm Des 10: 855-866, 2004.
    • (2004) Curr Pharm des , vol.10 , pp. 855-866
    • Baran, C.P.1    Zeigler, M.M.2    Tridandapani, S.3    Marsh, C.B.4
  • 14
    • 79960542894 scopus 로고    scopus 로고
    • Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
    • Bauernfeind F, Bartok E, Rieger A, Franchi L, Nunez G, and Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol 187: 613-617, 2011.
    • (2011) J Immunol , vol.187 , pp. 613-617
    • Bauernfeind, F.1    Bartok, E.2    Rieger, A.3    Franchi, L.4    Nunez, G.5    Hornung, V.6
  • 17
    • 51849103168 scopus 로고    scopus 로고
    • The microbial and danger signals that activate Nod-like receptors
    • Benko S, Philpott DJ, and Girardin SE. The microbial and danger signals that activate Nod-like receptors. Cytokine 43: 368-373, 2008.
    • (2008) Cytokine , vol.43 , pp. 368-373
    • Benko, S.1    Philpott, D.J.2    Girardin, S.E.3
  • 18
    • 84894385818 scopus 로고    scopus 로고
    • Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing
    • Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, and Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: effects of ASC gene deletion and silencing. Biochim Biophys Acta 1843: 836-845, 2014.
    • (2014) Biochim Biophys Acta , vol.1843 , pp. 836-845
    • Boini, K.M.1    Xia, M.2    Abais, J.M.3    Li, G.4    Pitzer, A.L.5    Gehr, T.W.6    Zhang, Y.7    Li, P.L.8
  • 19
    • 31744441475 scopus 로고    scopus 로고
    • Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
    • Boyden ED and Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 38: 240-244, 2006.
    • (2006) Nat Genet , vol.38 , pp. 240-244
    • Boyden, E.D.1    Dietrich, W.F.2
  • 20
    • 0037443542 scopus 로고    scopus 로고
    • Ca2 + stores and Ca2 + entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages
    • Brough D, Le Feuvre RA, Wheeler RD, Solovyova N, Hilfiker S, Rothwell NJ, and Verkhratsky A. Ca2 + stores and Ca2 + entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. J Immunol 170: 3029-3036, 2003.
    • (2003) J Immunol , vol.170 , pp. 3029-3036
    • Brough, D.1    Le Feuvre, R.A.2    Wheeler, R.D.3    Solovyova, N.4    Hilfiker, S.5    Rothwell, N.J.6    Verkhratsky, A.7
  • 21
    • 79952184583 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1- associated periodic syndrome (TRAPS)
    • Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, and Siegel RM. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1- associated periodic syndrome (TRAPS). J Exp Med 208: 519-533, 2011.
    • (2011) J Exp Med , vol.208 , pp. 519-533
    • Bulua, A.C.1    Simon, A.2    Maddipati, R.3    Pelletier, M.4    Park, H.5    Kim, K.Y.6    Sack, M.N.7    Kastner, D.L.8    Siegel, R.M.9
  • 22
    • 79961013790 scopus 로고    scopus 로고
    • The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering
    • Carta S, Tassi S, Pettinati I, Delfino L, Dinarello CA, and Rubartelli A. The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering. J Biol Chem 286: 27069-27080, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 27069-27080
    • Carta, S.1    Tassi, S.2    Pettinati, I.3    Delfino, L.4    Dinarello, C.A.5    Rubartelli, A.6
  • 24
    • 77749304033 scopus 로고    scopus 로고
    • Sterile inflammatory responses mediated by the NLRP3 inflammasome
    • Cassel SL and Sutterwala FS. Sterile inflammatory responses mediated by the NLRP3 inflammasome. Eur J Immunol 40: 607-611, 2010.
    • (2010) Eur J Immunol , vol.40 , pp. 607-611
    • Cassel, S.L.1    Sutterwala, F.S.2
  • 25
    • 66149156413 scopus 로고    scopus 로고
    • Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein
    • Chen J, Cha-Molstad H, Szabo A, and Shalev A. Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein. Am J Physiol Endocrinol Metab 296: E1133-E1139, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E1133-E1139
    • Chen, J.1    Cha-Molstad, H.2    Szabo, A.3    Shalev, A.4
  • 26
    • 84934313649 scopus 로고    scopus 로고
    • High mobility group box protein 1 as a novel vascular permeability factor derived from endothelial inflammasome activation during obesity
    • Chen Y, Pitzer AL, Li X, Xu M, Zhang Y, and Li PL. High mobility group box protein 1 as a novel vascular permeability factor derived from endothelial inflammasome activation during obesity. FASEB J 28: 688.5, 2014.
    • (2014) FASEB J , vol.28 , pp. 6885
    • Chen, Y.1    Pitzer, A.L.2    Li, X.3    Xu, M.4    Zhang, Y.5    Li, P.L.6
  • 27
    • 79955114904 scopus 로고    scopus 로고
    • Methotrexate in atherogenesis and cholesterol metabolism
    • Coomes E, Chan ES, and Reiss AB. Methotrexate in atherogenesis and cholesterol metabolism. Cholesterol 2011: 503028, 2011.
    • (2011) Cholesterol , vol.2011
    • Coomes, E.1    Chan, E.S.2    Reiss, A.B.3
  • 28
    • 34047261260 scopus 로고    scopus 로고
    • ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
    • Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, and Ojcius DM. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem 282: 2871-2879, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 2871-2879
    • Cruz, C.M.1    Rinna, A.2    Forman, H.J.3    Ventura, A.L.4    Persechini, P.M.5    Ojcius, D.M.6
  • 29
    • 54749122149 scopus 로고    scopus 로고
    • Immunoregulatory effects of homocysteine on cardiovascular diseases
    • Dai J and Wang X. Immunoregulatory effects of homocysteine on cardiovascular diseases. Sheng Li Xue Bao 59: 585-592, 2007.
    • (2007) Sheng Li Xue Bao , vol.59 , pp. 585-592
    • Dai, J.1    Wang, X.2
  • 30
    • 84890367292 scopus 로고    scopus 로고
    • New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease
    • De Nardo D, De Nardo CM, and Latz E. New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. Am J Pathol 184: 42-54, 2014.
    • (2014) Am J Pathol , vol.184 , pp. 42-54
    • De Nardo, D.1    De Nardo, C.M.2    Latz, E.3
  • 31
  • 32
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27: 519-550, 2009.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 33
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, and Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677, 2008.
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 34
    • 0034668833 scopus 로고    scopus 로고
    • Mitochondria and calcium: From cell signalling to cell death
    • Duchen MR. Mitochondria and calcium: from cell signalling to cell death. J Physiol 529 Pt 1: 57-68, 2000.
    • (2000) J Physiol , vol.529 , pp. 57-68
    • Duchen, M.R.1
  • 40
    • 84886674980 scopus 로고    scopus 로고
    • Fatty acidinduced mitochondrial uncoupling elicits inflammasomeindependent IL-1alpha and sterile vascular inflammation in atherosclerosis
    • Freigang S, Ampenberger F, Weiss A, Kanneganti TD, Iwakura Y, Hersberger M, and Kopf M. Fatty acidinduced mitochondrial uncoupling elicits inflammasomeindependent IL-1alpha and sterile vascular inflammation in atherosclerosis. Nat Immunol 14: 1045-1053, 2013.
    • (2013) Nat Immunol , vol.14 , pp. 1045-1053
    • Freigang, S.1    Ampenberger, F.2    Weiss, A.3    Kanneganti, T.D.4    Iwakura, Y.5    Hersberger, M.6    Kopf, M.7
  • 41
    • 0038359740 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
    • Fubini B and Hubbard A. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34: 1507-1516, 2003.
    • (2003) Free Radic Biol Med , vol.34 , pp. 1507-1516
    • Fubini, B.1    Hubbard, A.2
  • 46
    • 1042290321 scopus 로고    scopus 로고
    • Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
    • Hawkins PN, Lachmann HJ, Aganna E, and McDermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 50: 607-612, 2004.
    • (2004) Arthritis Rheum , vol.50 , pp. 607-612
    • Hawkins, P.N.1    Lachmann, H.J.2    Aganna, E.3    McDermott, M.F.4
  • 47
    • 84871514528 scopus 로고    scopus 로고
    • HMGB1 promotes the synthesis of pro-IL-1beta and pro- IL-18 by activation of p38 MAPK and NF-kappaB through receptors for advanced glycation end-products in macrophages
    • He Q, You H, Li XM, Liu TH, Wang P, and Wang BE. HMGB1 promotes the synthesis of pro-IL-1beta and pro- IL-18 by activation of p38 MAPK and NF-kappaB through receptors for advanced glycation end-products in macrophages. Asian Pac J Cancer Prev 13: 1365-1370, 2012.
    • (2012) Asian Pac J Cancer Prev , vol.13 , pp. 1365-1370
    • He, Q.1    You, H.2    Li, X.M.3    Liu, T.H.4    Wang, P.5    Wang, B.E.6
  • 51
    • 50249090764 scopus 로고    scopus 로고
    • A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes
    • Hewinson J, Moore SF, Glover C, Watts AG, and MacKenzie AB. A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes. J Immunol 180: 8410-8420, 2008.
    • (2008) J Immunol , vol.180 , pp. 8410-8420
    • Hewinson, J.1    Moore, S.F.2    Glover, C.3    Watts, A.G.4    Mackenzie, A.B.5
  • 52
    • 79751493607 scopus 로고    scopus 로고
    • Linking the inflammasome to obesity-related disease
    • Horng T and Hotamisligil GS. Linking the inflammasome to obesity-related disease. Nat Med 17: 164-165, 2011.
    • (2011) Nat Med , vol.17 , pp. 164-165
    • Horng, T.1    Hotamisligil, G.S.2
  • 54
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140: 900-917, 2010.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 55
    • 60549112774 scopus 로고    scopus 로고
    • Inflammasome recognition of influenza virus is essential for adaptive immune responses
    • Ichinohe T, Lee HK, Ogura Y, Flavell R, and Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 206: 79-87, 2009.
    • (2009) J Exp Med , vol.206 , pp. 79-87
    • Ichinohe, T.1    Lee, H.K.2    Ogura, Y.3    Flavell, R.4    Iwasaki, A.5
  • 57
    • 79960427714 scopus 로고    scopus 로고
    • Lipid raft redox signaling: Molecular mechanisms in health and disease
    • Jin S, Zhou F, Katirai F, and Li PL. Lipid raft redox signaling: molecular mechanisms in health and disease. Antioxid Redox Signal 15: 1043-1083, 2011.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1043-1083
    • Jin, S.1    Zhou, F.2    Katirai, F.3    Li, P.L.4
  • 59
    • 70349317039 scopus 로고    scopus 로고
    • Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
    • Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, and Sutterwala FS. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J Immunol 183: 3578-3581, 2009.
    • (2009) J Immunol , vol.183 , pp. 3578-3581
    • Joly, S.1    Ma, N.2    Sadler, J.J.3    Soll, D.R.4    Cassel, S.L.5    Sutterwala, F.S.6
  • 60
    • 84867770402 scopus 로고    scopus 로고
    • Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
    • Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, and Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem 287: 36617-36622, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 36617-36622
    • Juliana, C.1    Fernandes-Alnemri, T.2    Kang, S.3    Farias, A.4    Qin, F.5    Alnemri, E.S.6
  • 61
    • 4243897255 scopus 로고    scopus 로고
    • Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy
    • Khan N and Swartz H. Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy. Mol Cell Biochem 234-235: 341-357, 2002.
    • (2002) Mol Cell Biochem , vol.234-235 , pp. 341-357
    • Khan, N.1    Swartz, H.2
  • 62
    • 80053379974 scopus 로고    scopus 로고
    • Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
    • Kofoed EM and Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477: 592-595, 2011.
    • (2011) Nature , vol.477 , pp. 592-595
    • Kofoed, E.M.1    Vance, R.E.2
  • 65
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • Lamkanfi M. Emerging inflammasome effector mechanisms. Nat Rev Immunol 11: 213-220, 2011.
    • (2011) Nat Rev Immunol , vol.11 , pp. 213-220
    • Lamkanfi, M.1
  • 67
    • 34547897044 scopus 로고    scopus 로고
    • Lipid raft redox signaling platforms in endothelial dysfunction
    • Li PL, Zhang Y, and Yi F. Lipid raft redox signaling platforms in endothelial dysfunction. Antioxid Redox Signal 9: 1457-1470, 2007.
    • (2007) Antioxid Redox Signal , vol.9 , pp. 1457-1470
    • Li, P.L.1    Zhang, Y.2    Yi, F.3
  • 68
    • 84898470805 scopus 로고    scopus 로고
    • The role of the inflammasome in cardiovascular diseases
    • Li X, Deroide N, and Mallat Z. The role of the inflammasome in cardiovascular diseases. J Mol Med (Berl) 92: 307-319, 2014.
    • (2014) J Mol Med (Berl) , vol.92 , pp. 307-319
    • Li, X.1    Deroide, N.2    Mallat, Z.3
  • 69
    • 84900301850 scopus 로고    scopus 로고
    • Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: Implication of a novel role of inflammasome in atherogenesis
    • Li X, Zhang Y, Xia M, Gulbins E, Boini KM, and Li PL. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. PLoS One 9: e87552, 2014.
    • (2014) PLoS One , vol.9
    • Li, X.1    Zhang, Y.2    Xia, M.3    Gulbins, E.4    Boini, K.M.5    Li, P.L.6
  • 70
    • 84872290052 scopus 로고    scopus 로고
    • Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase- 1-mediated interleukin-1beta secretion
    • Liao PC, Chao LK, Chou JC, Dong WC, Lin CN, Lin CY, Chen A, Ka SM, Ho CL, and Hua KF. Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase- 1-mediated interleukin-1beta secretion. Inflamm Res 62: 89-96, 2013.
    • (2013) Inflamm Res , vol.62 , pp. 89-96
    • Liao, P.C.1    Chao, L.K.2    Chou, J.C.3    Dong, W.C.4    Lin, C.N.5    Lin, C.Y.6    Chen, A.7    Ka, S.M.8    Ho, C.L.9    Hua, K.F.10
  • 72
    • 79952076264 scopus 로고    scopus 로고
    • Ricin toxin activates the NALP3 inflammasome
    • Lindauer M, Wong J, and Magun B. Ricin toxin activates the NALP3 inflammasome. Toxins (Basel) 2: 1500-1514, 2010.
    • (2010) Toxins (Basel) , vol.2 , pp. 1500-1514
    • Lindauer, M.1    Wong, J.2    Magun, B.3
  • 75
    • 34247165763 scopus 로고    scopus 로고
    • ASC Ipaf and Cryopyrin/Nalp3: Bona fide intracellular adapters of the caspase-1 inflammasome
    • Mariathasan S. ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome. Microbes Infect 9: 664-671, 2007.
    • (2007) Microbes Infect , vol.9 , pp. 664-671
    • Mariathasan, S.1
  • 77
    • 77749304032 scopus 로고    scopus 로고
    • Signaling by ROS drives inflammasome activation
    • Martinon F. Signaling by ROS drives inflammasome activation. Eur J Immunol 40: 616-619, 2010.
    • (2010) Eur J Immunol , vol.40 , pp. 616-619
    • Martinon, F.1
  • 78
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
    • Martinon F, Agostini L, Meylan E, and Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol 14: 1929-1934, 2004.
    • (2004) Curr Biol , vol.14 , pp. 1929-1934
    • Martinon, F.1    Agostini, L.2    Meylan, E.3    Tschopp, J.4
  • 79
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F, Burns K, and Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426, 2002.
    • (2002) Mol Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 80
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, and Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241, 2006.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 81
    • 22444433175 scopus 로고    scopus 로고
    • NLRs join TLRs as innate sensors of pathogens
    • Martinon F and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26: 447-454, 2005.
    • (2005) Trends Immunol , vol.26 , pp. 447-454
    • Martinon, F.1    Tschopp, J.2
  • 82
    • 84882285470 scopus 로고    scopus 로고
    • Specific inflammasomes in complex diseases
    • Masters SL. Specific inflammasomes in complex diseases. Clin Immunol 147: 223-228, 2013.
    • (2013) Clin Immunol , vol.147 , pp. 223-228
    • Masters, S.L.1
  • 84
    • 0034939382 scopus 로고    scopus 로고
    • Elevated interleukin-18 levels in the urine of nephrotic patients
    • Matsumoto K and Kanmatsuse K. Elevated interleukin-18 levels in the urine of nephrotic patients. Nephron 88: 334-339, 2001.
    • (2001) Nephron , vol.88 , pp. 334-339
    • Matsumoto, K.1    Kanmatsuse, K.2
  • 85
    • 47849120473 scopus 로고    scopus 로고
    • Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
    • Meissner F, Molawi K, and Zychlinsky A. Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat Immunol 9: 866-872, 2008.
    • (2008) Nat Immunol , vol.9 , pp. 866-872
    • Meissner, F.1    Molawi, K.2    Zychlinsky, A.3
  • 86
    • 77956601381 scopus 로고    scopus 로고
    • Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease
    • Meissner F, Seger RA, Moshous D, Fischer A, Reichenbach J, and Zychlinsky A. Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease. Blood 116: 1570-1573, 2010.
    • (2010) Blood , vol.116 , pp. 1570-1573
    • Meissner, F.1    Seger, R.A.2    Moshous, D.3    Fischer, A.4    Reichenbach, J.5    Zychlinsky, A.6
  • 89
    • 84893663061 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet
    • Mohamed IN, Hafez SS, Fairaq A, Ergul A, Imig JD, and El-Remessy AB. Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet. Diabetologia 57: 413-423, 2014.
    • (2014) Diabetologia , vol.57 , pp. 413-423
    • Mohamed, I.N.1    Hafez, S.S.2    Fairaq, A.3    Ergul, A.4    Imig, J.D.5    El-Remessy, A.B.6
  • 90
    • 0035209916 scopus 로고    scopus 로고
    • Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1
    • Monack DM, Detweiler CS, and Falkow S. Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1. Cell Microbiol 3: 825-837, 2001.
    • (2001) Cell Microbiol , vol.3 , pp. 825-837
    • Monack, D.M.1    Detweiler, C.S.2    Falkow, S.3
  • 91
    • 73649189052 scopus 로고
    • Wellsm. Urticaria deafness, and amyloidosis: A new heredo-familial syndrome
    • Muckle TJ, Wellsm. Urticaria, deafness, and amyloidosis: a new heredo-familial syndrome. Q J Med 31: 235-248, 1962.
    • (1962) Q J Med , vol.31 , pp. 235-248
    • Muckle, T.J.1
  • 92
    • 84903768213 scopus 로고    scopus 로고
    • GSK's darapladib failures dim hopes for antiinflammatory heart drugs
    • Mullard A. GSK's darapladib failures dim hopes for antiinflammatory heart drugs. Nat Rev Drug Discov 13: 481-482, 2014.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 481-482
    • Mullard, A.1
  • 93
    • 84879596906 scopus 로고    scopus 로고
    • K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
    • Munoz-Planillo R, Kuffa P, Martinez-Colon G, Smith BL, Rajendiran TM, and Nunez G. K( + ) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38: 1142-1153, 2013.
    • (2013) Immunity , vol.38 , pp. 1142-1153
    • Munoz-Planillo, R.1    Kuffa, P.2    Martinez-Colon, G.3    Smith, B.L.4    Rajendiran, T.M.5    Nunez, G.6
  • 97
    • 78650988141 scopus 로고    scopus 로고
    • Involvement of xanthine oxidase and hypoxiainducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta
    • Nicholas SA, Bubnov VV, Yasinska IM, and Sumbayev VV. Involvement of xanthine oxidase and hypoxiainducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta. Cell Mol Life Sci 68: 151-158, 2011.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 151-158
    • Nicholas, S.A.1    Bubnov, V.V.2    Yasinska, I.M.3    Sumbayev, V.V.4
  • 99
    • 84875730197 scopus 로고    scopus 로고
    • Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status
    • Nishi Y, Satoh M, Nagasu H, Kadoya H, Ihoriya C, Kidokoro K, Sasaki T, and Kashihara N. Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status. Kidney Int 83: 662-673, 2013.
    • (2013) Kidney Int , vol.83 , pp. 662-673
    • Nishi, Y.1    Satoh, M.2    Nagasu, H.3    Kadoya, H.4    Ihoriya, C.5    Kidokoro, K.6    Sasaki, T.7    Kashihara, N.8
  • 100
    • 0346350694 scopus 로고    scopus 로고
    • Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties
    • O'Connor W, Jr., Harton JA, Zhu X, Linhoff MW, and Ting JP. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. J Immunol 171: 6329-6333, 2003.
    • (2003) J Immunol , vol.171 , pp. 6329-6333
    • O'Connor, W.1    Harton, J.A.2    Zhu, X.3    Linhoff, M.W.4    Ting, J.P.5
  • 103
  • 104
    • 33750473352 scopus 로고    scopus 로고
    • Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor
    • Pelegrin P and Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor. EMBO J 25: 5071-5082, 2006.
    • (2006) EMBO J , vol.25 , pp. 5071-5082
    • Pelegrin, P.1    Surprenant, A.2
  • 105
    • 67651172779 scopus 로고    scopus 로고
    • Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates
    • Pelegrin P and Surprenant A. Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates. EMBO J 28: 2114-2127, 2009.
    • (2009) EMBO J , vol.28 , pp. 2114-2127
    • Pelegrin, P.1    Surprenant, A.2
  • 106
    • 36849095530 scopus 로고    scopus 로고
    • The inflammasome, autoinflammatory diseases, and gout
    • Petrilli V and Martinon F. The inflammasome, autoinflammatory diseases, and gout. Joint Bone Spine 74: 571-576, 2007.
    • (2007) Joint Bone Spine , vol.74 , pp. 571-576
    • Petrilli, V.1    Martinon, F.2
  • 107
    • 34548027736 scopus 로고    scopus 로고
    • Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
    • Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, and Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14: 1583-1589, 2007.
    • (2007) Cell Death Differ , vol.14 , pp. 1583-1589
    • Petrilli, V.1    Papin, S.2    Dostert, C.3    Mayor, A.4    Martinon, F.5    Tschopp, J.6
  • 109
    • 54149111582 scopus 로고    scopus 로고
    • Homocysteine up-regulates vascular transmembrane chemokine CXCL16 and induces CXCR6 + lymphocyte recruitment in vitro and in vivo
    • Postea O, Koenen RR, Hristov M, Weber C, and Ludwig A. Homocysteine up-regulates vascular transmembrane chemokine CXCL16 and induces CXCR6 + lymphocyte recruitment in vitro and in vivo. J Cell Mol Med 12: 1700-1709, 2008.
    • (2008) J Cell Mol Med , vol.12 , pp. 1700-1709
    • Postea, O.1    Koenen, R.R.2    Hristov, M.3    Weber, C.4    Ludwig, A.5
  • 110
    • 84872782298 scopus 로고    scopus 로고
    • Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
    • Py BF, Kim MS, Vakifahmetoglu-Norberg H, and Yuan J. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell 49: 331-338, 2013.
    • (2013) Mol Cell , vol.49 , pp. 331-338
    • Py, B.F.1    Kim, M.S.2    Vakifahmetoglu-Norberg, H.3    Yuan, J.4
  • 112
    • 84870781498 scopus 로고    scopus 로고
    • Phospholipase A2 enzymes and the risk of atherosclerosis
    • Rosenson RS and Hurt-Camejo E. Phospholipase A2 enzymes and the risk of atherosclerosis. Eur Heart J 33: 2899-2909, 2012.
    • (2012) Eur Heart J , vol.33 , pp. 2899-2909
    • Rosenson, R.S.1    Hurt-Camejo, E.2
  • 115
    • 37549002511 scopus 로고    scopus 로고
    • The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
    • Shao W, Yeretssian G, Doiron K, Hussain SN, and Saleh M. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 282: 36321-36329, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 36321-36329
    • Shao, W.1    Yeretssian, G.2    Doiron, K.3    Hussain, S.N.4    Saleh, M.5
  • 117
    • 40649094344 scopus 로고    scopus 로고
    • Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells
    • Silva JP, Proenca F, and Coutinho OP. Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells. Free Radic Res 42: 57-69, 2008.
    • (2008) Free Radic Res , vol.42 , pp. 57-69
    • Silva, J.P.1    Proenca, F.2    Coutinho, O.P.3
  • 120
    • 84876237736 scopus 로고    scopus 로고
    • The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
    • Subramanian N, Natarajan K, Clatworthy MR, Wang Z, and Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell 153: 348-361, 2013.
    • (2013) Cell , vol.153 , pp. 348-361
    • Subramanian, N.1    Natarajan, K.2    Clatworthy, M.R.3    Wang, Z.4    Germain, R.N.5
  • 121
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • Surprenant A, Rassendren F, Kawashima E, North RA, and Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272: 735-738, 1996.
    • (1996) Science , vol.272 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 122
    • 34547743231 scopus 로고    scopus 로고
    • The inflammasome in pathogen recognition and inflammation
    • Sutterwala FS, Ogura Y, and Flavell RA. The inflammasome in pathogen recognition and inflammation. J Leukoc Biol 82: 259-264, 2007.
    • (2007) J Leukoc Biol , vol.82 , pp. 259-264
    • Sutterwala, F.S.1    Ogura, Y.2    Flavell, R.A.3
  • 123
    • 84860792654 scopus 로고    scopus 로고
    • Role of the inflammasome in myocardial infarction
    • Takahashi M. Role of the inflammasome in myocardial infarction. Trends Cardiovasc Med 21: 37-41, 2011.
    • (2011) Trends Cardiovasc Med , vol.21 , pp. 37-41
    • Takahashi, M.1
  • 124
    • 70249117528 scopus 로고    scopus 로고
    • Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response
    • Tassi S, Carta S, Vene R, Delfino L, Ciriolo MR, and Rubartelli A. Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response. J Immunol 183: 1456-1462, 2009.
    • (2009) J Immunol , vol.183 , pp. 1456-1462
    • Tassi, S.1    Carta, S.2    Vene, R.3    Delfino, L.4    Ciriolo, M.R.5    Rubartelli, A.6
  • 126
    • 84880651157 scopus 로고    scopus 로고
    • The complement membrane attack complex triggers intracellular Ca2 + fluxes leading to NLRP3 inflammasome activation
    • Triantafilou K, Hughes TR, Triantafilou M, and Morgan BP. The complement membrane attack complex triggers intracellular Ca2 + fluxes leading to NLRP3 inflammasome activation. J Cell Sci 126: 2903-2913, 2013.
    • (2013) J Cell Sci , vol.126 , pp. 2903-2913
    • Triantafilou, K.1    Hughes, T.R.2    Triantafilou, M.3    Morgan, B.P.4
  • 127
    • 77649179433 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
    • Tschopp J and Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 10: 210-215, 2010.
    • (2010) Nat Rev Immunol , vol.10 , pp. 210-215
    • Tschopp, J.1    Schroder, K.2
  • 133
    • 84862235344 scopus 로고    scopus 로고
    • Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation
    • Wang C, Pan Y, Zhang QY, Wang FM, and Kong LD. Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation. PLoS One 7: e38285, 2012.
    • (2012) PLoS One , vol.7
    • Wang, C.1    Pan, Y.2    Zhang, Q.Y.3    Wang, F.M.4    Kong, L.D.5
  • 134
    • 0036847780 scopus 로고    scopus 로고
    • Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: Role of chemokine and adhesion molecules
    • Wang G, Woo CW, Sung FL, Siow YL, and O K. Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules. Arterioscler Thromb Vasc Biol 22: 1777-1783, 2002.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 1777-1783
    • Wang, G.1    Woo, C.W.2    Sung, F.L.3    Siow, Y.L.4
  • 135
    • 67349106386 scopus 로고    scopus 로고
    • Protection by tetrahydroxystilbene glucoside against cerebral ischemia: Involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation
    • Wang T, Gu J, Wu PF, Wang F, Xiong Z, Yang YJ, Wu WN, Dong LD, and Chen JG. Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radic Biol Med 47: 229-240, 2009.
    • (2009) Free Radic Biol Med , vol.47 , pp. 229-240
    • Wang, T.1    Gu, J.2    Wu, P.F.3    Wang, F.4    Xiong, Z.5    Yang, Y.J.6    Wu, W.N.7    Dong, L.D.8    Chen, J.G.9
  • 136
    • 84879357128 scopus 로고    scopus 로고
    • Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
    • Wang W, Wang C, Ding XQ, Pan Y, Gu TT, Wang MX, Liu YL, Wang FM, Wang SJ, and Kong LD. Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. Br J Pharmacol 169: 1352-1371, 2013.
    • (2013) Br J Pharmacol , vol.169 , pp. 1352-1371
    • Wang, W.1    Wang, C.2    Ding, X.Q.3    Pan, Y.4    Gu, T.T.5    Wang, M.X.6    Liu, Y.L.7    Wang, F.M.8    Wang, S.J.9    Kong, L.D.10
  • 138
    • 76249088729 scopus 로고    scopus 로고
    • ROS-dependent signaling mechanisms for hypoxic Ca(2 + ) responses in pulmonary artery myocytes
    • Wang YX and Zheng YM. ROS-dependent signaling mechanisms for hypoxic Ca(2 + ) responses in pulmonary artery myocytes. Antioxid Redox Signal 12: 611-623, 2010.
    • (2010) Antioxid Redox Signal , vol.12 , pp. 611-623
    • Wang, Y.X.1    Zheng, Y.M.2
  • 140
    • 79955038882 scopus 로고    scopus 로고
    • Fatty acid-induced NLRP3- ASC inflammasome activation interferes with insulin signaling
    • Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, and Ting JP. Fatty acid-induced NLRP3- ASC inflammasome activation interferes with insulin signaling. Nat Immunol 12: 408-415, 2011.
    • (2011) Nat Immunol , vol.12 , pp. 408-415
    • Wen, H.1    Gris, D.2    Lei, Y.3    Jha, S.4    Zhang, L.5    Huang, M.T.6    Brickey, W.J.7    Ting, J.P.8
  • 141
    • 68149100523 scopus 로고    scopus 로고
    • NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasomedependent and -independent pathways
    • Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, and Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasomedependent and -independent pathways. J Immunol 183: 2008-2015, 2009.
    • (2009) J Immunol , vol.183 , pp. 2008-2015
    • Willingham, S.B.1    Allen, I.C.2    Bergstralh, D.T.3    Brickey, W.J.4    Huang, M.T.5    Taxman, D.J.6    Duncan, J.A.7    Ting, J.P.8
  • 142
    • 84875464393 scopus 로고    scopus 로고
    • Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury
    • Wu J, Yan Z, Schwartz DE, Yu J, Malik AB, and Hu G. Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury. J Immunol 190: 3590-3599, 2013.
    • (2013) J Immunol , vol.190 , pp. 3590-3599
    • Wu, J.1    Yan, Z.2    Schwartz, D.E.3    Yu, J.4    Malik, A.B.5    Hu, G.6
  • 143
    • 84899564349 scopus 로고    scopus 로고
    • Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin
    • Xia M, Boini KM, Abais JM, Xu M, Zhang Y, and Li PL. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am J Pathol 184: 1617-1628, 2014.
    • (2014) Am J Pathol , vol.184 , pp. 1617-1628
    • Xia, M.1    Boini, K.M.2    Abais, J.M.3    Xu, M.4    Zhang, Y.5    Li, P.L.6
  • 144
    • 78751475177 scopus 로고    scopus 로고
    • Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin
    • Xia M, Zhang C, Boini KM, Thacker AM, and Li PL. Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res 89: 401-409, 2011.
    • (2011) Cardiovasc Res , vol.89 , pp. 401-409
    • Xia, M.1    Zhang, C.2    Boini, K.M.3    Thacker, A.M.4    Li, P.L.5
  • 146
    • 67649831360 scopus 로고    scopus 로고
    • NLRP3/cryopyrin is necessary for interleukin- 1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
    • Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, Grant EP, Coyle AJ, Misaghi A, Hoffman HM, and Gallo RL. NLRP3/cryopyrin is necessary for interleukin- 1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem 284: 12762-12771, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 12762-12771
    • Yamasaki, K.1    Muto, J.2    Taylor, K.R.3    Cogen, A.L.4    Audish, D.5    Bertin, J.6    Grant, E.P.7    Coyle, A.J.8    Misaghi, A.9    Hoffman, H.M.10    Gallo, R.L.11
  • 148
    • 38349003348 scopus 로고    scopus 로고
    • Mechanisms of homocysteine-induced glomerular injury and sclerosis
    • Yi F and Li PL. Mechanisms of homocysteine-induced glomerular injury and sclerosis. Am J Nephrol 28: 254-264, 2008.
    • (2008) Am J Nephrol , vol.28 , pp. 254-264
    • Yi, F.1    Li, P.L.2
  • 150
    • 84865820621 scopus 로고    scopus 로고
    • Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia
    • Zhang C, Boini KM, Xia M, Abais JM, Li X, Liu Q, and Li PL. Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension 60: 154-162, 2012.
    • (2012) Hypertension , vol.60 , pp. 154-162
    • Zhang, C.1    Boini, K.M.2    Xia, M.3    Abais, J.M.4    Li, X.5    Liu, Q.6    Li, P.L.7
  • 151
    • 77950520014 scopus 로고    scopus 로고
    • Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene
    • Zhang C, Hu JJ, Xia M, Boini KM, Brimson CA, Laperle LA, and Li PL. Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. Free Radic Biol Med 48: 1109-1117, 2010.
    • (2010) Free Radic Biol Med , vol.48 , pp. 1109-1117
    • Zhang, C.1    Hu, J.J.2    Xia, M.3    Boini, K.M.4    Brimson, C.A.5    Laperle, L.A.6    Li, P.L.7
  • 152
    • 84934313650 scopus 로고    scopus 로고
    • Coronary endothelial dysfunction induced by Nlrp3 inflammasome activation during hypercholesterolemia: Beyond inflammation
    • Zhang Y, Li X, Pitzer AL, and Li PL. Coronary endothelial dysfunction induced by Nlrp3 inflammasome activation during hypercholesterolemia: beyond inflammation. FASEB J 28: 851.13, 2014.
    • (2014) FASEB J , vol.28 , pp. 85113
    • Zhang, Y.1    Li, X.2    Pitzer, A.L.3    Li, P.L.4
  • 153
    • 80053349020 scopus 로고    scopus 로고
    • The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
    • Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, and Shao F. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477: 596-600, 2011.
    • (2011) Nature , vol.477 , pp. 596-600
    • Zhao, Y.1    Yang, J.2    Shi, J.3    Gong, Y.N.4    Lu, Q.5    Xu, H.6    Liu, L.7    Shao, F.8
  • 154
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • Zhou R, Tardivel A, Thorens B, Choi I, and Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11: 136-140, 2010.
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 155
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R, Yazdi AS, Menu P, and Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 469: 221-225, 2011.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.