-
1
-
-
84934313648
-
Contribution of guanine nucleotide exchange factor Vav2 to homocysteine- induced NLRP3 inflammasome activation in mouse podocytes
-
Abais JM, Xia M, Boini KM, and Li PL. Contribution of guanine nucleotide exchange factor Vav2 to homocysteine- induced NLRP3 inflammasome activation in mouse podocytes. FASEB J 28: 1063.6, 2014.
-
(2014)
FASEB J
, vol.28
, pp. 10636
-
-
Abais, J.M.1
Xia, M.2
Boini, K.M.3
Li, P.L.4
-
2
-
-
84907588640
-
Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein during hyperhomocysteinemia
-
Abais JM, Xia M, Li G, Chen Y, Conley SM, Gehr TW, Boini KM, and Li PL. Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein during hyperhomocysteinemia. J Biol Chem 289: 27159, 2014.
-
(2014)
J Biol Chem
, vol.289
-
-
Abais, J.M.1
Xia, M.2
Li, G.3
Chen, Y.4
Conley, S.M.5
Gehr, T.W.6
Boini, K.M.7
Li, P.L.8
-
3
-
-
84888607647
-
Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia
-
Abais JM, Xia M, Li G, Gehr TW, Boini KM, and Li PL. Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia. Free Radic Biol Med 67: 211-220, 2014.
-
(2014)
Free Radic Biol Med
, vol.67
, pp. 211-220
-
-
Abais, J.M.1
Xia, M.2
Li, G.3
Gehr, T.W.4
Boini, K.M.5
Li, P.L.6
-
4
-
-
84875730240
-
NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia
-
Abais JM, Zhang C, Xia M, Liu Q, Gehr TW, Boini KM, and Li PL. NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid Redox Signal 18: 1537-1548, 2013.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1537-1548
-
-
Abais, J.M.1
Zhang, C.2
Xia, M.3
Liu, Q.4
Gehr, T.W.5
Boini, K.M.6
Li, P.L.7
-
5
-
-
0036745064
-
Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis
-
Aganna E, Martinon F, Hawkins PN, Ross JB, Swan DC, Booth DR, Lachmann HJ, Bybee A, Gaudet R, Woo P, Feighery C, Cotter FE, Thome M, Hitman GA, Tschopp J, and McDermott MF. Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. Arthritis Rheum 46: 2445-2452, 2002.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2445-2452
-
-
Aganna, E.1
Martinon, F.2
Hawkins, P.N.3
Ross, J.B.4
Swan, D.C.5
Booth, D.R.6
Lachmann, H.J.7
Bybee, A.8
Gaudet, R.9
Woo, P.10
Feighery, C.11
Cotter, F.E.12
Thome, M.13
Hitman, G.A.14
Tschopp, J.15
McDermott, M.F.16
-
6
-
-
1642285783
-
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
-
Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, and Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20: 319-325, 2004.
-
(2004)
Immunity
, vol.20
, pp. 319-325
-
-
Agostini, L.1
Martinon, F.2
Burns, K.3
McDermott, M.F.4
Hawkins, P.N.5
Tschopp, J.6
-
7
-
-
84881344806
-
TNF-Alpha may mediate inflammasome activation in the absence of bacterial infection in more than one way
-
Alvarez S, Munoz-Fernandez MA. TNF-Alpha may mediate inflammasome activation in the absence of bacterial infection in more than one way. PLoS One 8: e71477, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Alvarez, S.1
Munoz-Fernandez, M.A.2
-
8
-
-
84856403035
-
NLRP3 inflammasome- mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout
-
Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, and Teixeira MM. NLRP3 inflammasome- mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout. Arthritis Rheum 64: 474-484, 2012.
-
(2012)
Arthritis Rheum
, vol.64
, pp. 474-484
-
-
Amaral, F.A.1
Costa, V.V.2
Tavares, L.D.3
Sachs, D.4
Coelho, F.M.5
Fagundes, C.T.6
Soriani, F.M.7
Silveira, T.N.8
Cunha, L.D.9
Zamboni, D.S.10
Quesniaux, V.11
Peres, R.S.12
Cunha, T.M.13
Cunha, F.Q.14
Ryffel, B.15
Souza, D.G.16
Teixeira, M.M.17
-
9
-
-
80655144737
-
Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly
-
Bae JY and Park HH. Crystal structure of NALP3 protein pyrin domain (PYD) and its implications in inflammasome assembly. J Biol Chem 286: 39528-39536, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 39528-39536
-
-
Bae, J.Y.1
Park, H.H.2
-
10
-
-
84899934630
-
Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation
-
Bakker PJ, Butter LM, Kors L, Teske GJ, Aten J, Sutterwala FS, Florquin S, and Leemans JC. Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. Kidney Int 85: 1112-1122, 2014.
-
(2014)
Kidney Int
, vol.85
, pp. 1112-1122
-
-
Bakker, P.J.1
Butter, L.M.2
Kors, L.3
Teske, G.J.4
Aten, J.5
Sutterwala, F.S.6
Florquin, S.7
Leemans, J.C.8
-
11
-
-
1642286961
-
The role of ROS and RNS in regulating life and death of blood monocytes
-
Baran CP, Zeigler MM, Tridandapani S, and Marsh CB. The role of ROS and RNS in regulating life and death of blood monocytes. Curr Pharm Des 10: 855-866, 2004.
-
(2004)
Curr Pharm des
, vol.10
, pp. 855-866
-
-
Baran, C.P.1
Zeigler, M.M.2
Tridandapani, S.3
Marsh, C.B.4
-
12
-
-
84862270214
-
P2X7 receptorstimulation causes fever via PGE2 and IL-1beta release
-
Barbera-Cremades M, Baroja-Mazo A, Gomez AI, Machado F, Di Virgilio F, and Pelegrin P. P2X7 receptorstimulation causes fever via PGE2 and IL-1beta release. FASEB J 26: 2951-2962, 2012.
-
(2012)
FASEB J
, vol.26
, pp. 2951-2962
-
-
Barbera-Cremades, M.1
Baroja-Mazo, A.2
Gomez, A.I.3
Machado, F.4
Di Virgilio, F.5
Pelegrin, P.6
-
13
-
-
79951578449
-
Inflammasomes: Current understanding and open questions
-
Bauernfeind F, Ablasser A, Bartok E, Kim S, Schmid- Burgk J, Cavlar T, and Hornung V. Inflammasomes: current understanding and open questions. Cell Mol Life Sci 68: 765-783, 2011.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 765-783
-
-
Bauernfeind, F.1
Ablasser, A.2
Bartok, E.3
Kim, S.4
Schmid-Burgk, J.5
Cavlar, T.6
Hornung, V.7
-
14
-
-
79960542894
-
Cutting edge: Reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
Bauernfeind F, Bartok E, Rieger A, Franchi L, Nunez G, and Hornung V. Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome. J Immunol 187: 613-617, 2011.
-
(2011)
J Immunol
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
15
-
-
84867304098
-
NLRP3 inflammasome activity is negatively controlled by miR-223
-
Bauernfeind F, Rieger A, Schildberg FA, Knolle PA, Schmid-Burgk JL, and Hornung V. NLRP3 inflammasome activity is negatively controlled by miR-223. J Immunol 189: 4175-4181, 2012.
-
(2012)
J Immunol
, vol.189
, pp. 4175-4181
-
-
Bauernfeind, F.1
Rieger, A.2
Schildberg, F.A.3
Knolle, P.A.4
Schmid-Burgk, J.L.5
Hornung, V.6
-
16
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, Mac- Donald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, and Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol 183: 787-791, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
Macdonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
17
-
-
51849103168
-
The microbial and danger signals that activate Nod-like receptors
-
Benko S, Philpott DJ, and Girardin SE. The microbial and danger signals that activate Nod-like receptors. Cytokine 43: 368-373, 2008.
-
(2008)
Cytokine
, vol.43
, pp. 368-373
-
-
Benko, S.1
Philpott, D.J.2
Girardin, S.E.3
-
18
-
-
84894385818
-
Activation of inflammasomes in podocyte injury of mice on the high fat diet: Effects of ASC gene deletion and silencing
-
Boini KM, Xia M, Abais JM, Li G, Pitzer AL, Gehr TW, Zhang Y, and Li PL. Activation of inflammasomes in podocyte injury of mice on the high fat diet: effects of ASC gene deletion and silencing. Biochim Biophys Acta 1843: 836-845, 2014.
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 836-845
-
-
Boini, K.M.1
Xia, M.2
Abais, J.M.3
Li, G.4
Pitzer, A.L.5
Gehr, T.W.6
Zhang, Y.7
Li, P.L.8
-
19
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
Boyden ED and Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet 38: 240-244, 2006.
-
(2006)
Nat Genet
, vol.38
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
20
-
-
0037443542
-
Ca2 + stores and Ca2 + entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages
-
Brough D, Le Feuvre RA, Wheeler RD, Solovyova N, Hilfiker S, Rothwell NJ, and Verkhratsky A. Ca2 + stores and Ca2 + entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. J Immunol 170: 3029-3036, 2003.
-
(2003)
J Immunol
, vol.170
, pp. 3029-3036
-
-
Brough, D.1
Le Feuvre, R.A.2
Wheeler, R.D.3
Solovyova, N.4
Hilfiker, S.5
Rothwell, N.J.6
Verkhratsky, A.7
-
21
-
-
79952184583
-
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1- associated periodic syndrome (TRAPS)
-
Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, and Siegel RM. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1- associated periodic syndrome (TRAPS). J Exp Med 208: 519-533, 2011.
-
(2011)
J Exp Med
, vol.208
, pp. 519-533
-
-
Bulua, A.C.1
Simon, A.2
Maddipati, R.3
Pelletier, M.4
Park, H.5
Kim, K.Y.6
Sack, M.N.7
Kastner, D.L.8
Siegel, R.M.9
-
22
-
-
79961013790
-
The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering
-
Carta S, Tassi S, Pettinati I, Delfino L, Dinarello CA, and Rubartelli A. The rate of interleukin-1beta secretion in different myeloid cells varies with the extent of redox response to Toll-like receptor triggering. J Biol Chem 286: 27069-27080, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 27069-27080
-
-
Carta, S.1
Tassi, S.2
Pettinati, I.3
Delfino, L.4
Dinarello, C.A.5
Rubartelli, A.6
-
23
-
-
47849132947
-
The Nalp3 inflammasome is essential for the development of silicosis
-
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, and Sutterwala FS. The Nalp3 inflammasome is essential for the development of silicosis. Proc Natl Acad Sci U S A 105: 9035-9040, 2008.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 9035-9040
-
-
Cassel, S.L.1
Eisenbarth, S.C.2
Iyer, S.S.3
Sadler, J.J.4
Colegio, O.R.5
Tephly, L.A.6
Carter, A.B.7
Rothman, P.B.8
Flavell, R.A.9
Sutterwala, F.S.10
-
24
-
-
77749304033
-
Sterile inflammatory responses mediated by the NLRP3 inflammasome
-
Cassel SL and Sutterwala FS. Sterile inflammatory responses mediated by the NLRP3 inflammasome. Eur J Immunol 40: 607-611, 2010.
-
(2010)
Eur J Immunol
, vol.40
, pp. 607-611
-
-
Cassel, S.L.1
Sutterwala, F.S.2
-
25
-
-
66149156413
-
Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein
-
Chen J, Cha-Molstad H, Szabo A, and Shalev A. Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein. Am J Physiol Endocrinol Metab 296: E1133-E1139, 2009.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, pp. E1133-E1139
-
-
Chen, J.1
Cha-Molstad, H.2
Szabo, A.3
Shalev, A.4
-
26
-
-
84934313649
-
High mobility group box protein 1 as a novel vascular permeability factor derived from endothelial inflammasome activation during obesity
-
Chen Y, Pitzer AL, Li X, Xu M, Zhang Y, and Li PL. High mobility group box protein 1 as a novel vascular permeability factor derived from endothelial inflammasome activation during obesity. FASEB J 28: 688.5, 2014.
-
(2014)
FASEB J
, vol.28
, pp. 6885
-
-
Chen, Y.1
Pitzer, A.L.2
Li, X.3
Xu, M.4
Zhang, Y.5
Li, P.L.6
-
27
-
-
79955114904
-
Methotrexate in atherogenesis and cholesterol metabolism
-
Coomes E, Chan ES, and Reiss AB. Methotrexate in atherogenesis and cholesterol metabolism. Cholesterol 2011: 503028, 2011.
-
(2011)
Cholesterol
, vol.2011
-
-
Coomes, E.1
Chan, E.S.2
Reiss, A.B.3
-
28
-
-
34047261260
-
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
-
Cruz CM, Rinna A, Forman HJ, Ventura AL, Persechini PM, and Ojcius DM. ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J Biol Chem 282: 2871-2879, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 2871-2879
-
-
Cruz, C.M.1
Rinna, A.2
Forman, H.J.3
Ventura, A.L.4
Persechini, P.M.5
Ojcius, D.M.6
-
29
-
-
54749122149
-
Immunoregulatory effects of homocysteine on cardiovascular diseases
-
Dai J and Wang X. Immunoregulatory effects of homocysteine on cardiovascular diseases. Sheng Li Xue Bao 59: 585-592, 2007.
-
(2007)
Sheng Li Xue Bao
, vol.59
, pp. 585-592
-
-
Dai, J.1
Wang, X.2
-
30
-
-
84890367292
-
New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease
-
De Nardo D, De Nardo CM, and Latz E. New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. Am J Pathol 184: 42-54, 2014.
-
(2014)
Am J Pathol
, vol.184
, pp. 42-54
-
-
De Nardo, D.1
De Nardo, C.M.2
Latz, E.3
-
32
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 27: 519-550, 2009.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
33
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, and Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677, 2008.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
34
-
-
0034668833
-
Mitochondria and calcium: From cell signalling to cell death
-
Duchen MR. Mitochondria and calcium: from cell signalling to cell death. J Physiol 529 Pt 1: 57-68, 2000.
-
(2000)
J Physiol
, vol.529
, pp. 57-68
-
-
Duchen, M.R.1
-
35
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, Abela GS, Franchi L, Nunez G, Schnurr M, Espevik T, Lien E, Fitzgerald KA, Rock KL, Moore KJ, Wright SD, Hornung V, and Latz E. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464: 1357-1361, 2010.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
36
-
-
70449448992
-
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
-
Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, Bergstralh DT, Jarvis GA, Sparling PF, and Ting JP. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome. J Immunol 182: 6460-6469, 2009.
-
(2009)
J Immunol
, vol.182
, pp. 6460-6469
-
-
Duncan, J.A.1
Gao, X.2
Huang, M.T.3
O'Connor, B.P.4
Thomas, C.E.5
Willingham, S.B.6
Bergstralh, D.T.7
Jarvis, G.A.8
Sparling, P.F.9
Ting, J.P.10
-
37
-
-
84895167177
-
Deletion of thioredoxininteracting protein preserves retinal neuronal function by preventing inflammation and vascular injury
-
El-Azab MF, Baldowski BR, Mysona BA, Shanab AY, Mohamed IN, Abdelsaid MA, Matragoon S, Bollinger KE, Saul A, and El-Remessy AB. Deletion of thioredoxininteracting protein preserves retinal neuronal function by preventing inflammation and vascular injury. Br J Pharmacol 171: 1299-1313, 2014.
-
(2014)
Br J Pharmacol
, vol.171
, pp. 1299-1313
-
-
El-Azab, M.F.1
Baldowski, B.R.2
Mysona, B.A.3
Shanab, A.Y.4
Mohamed, I.N.5
Abdelsaid, M.A.6
Matragoon, S.7
Bollinger, K.E.8
Saul, A.9
El-Remessy, A.B.10
-
38
-
-
33847376042
-
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
-
Faustin B, Lartigue L, Bruey JM, Luciano F, Sergienko E, Bailly-Maitre B, Volkmann N, Hanein D, Rouiller I, and Reed JC. Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation. Mol Cell 25: 713-724, 2007.
-
(2007)
Mol Cell
, vol.25
, pp. 713-724
-
-
Faustin, B.1
Lartigue, L.2
Bruey, J.M.3
Luciano, F.4
Sergienko, E.5
Bailly-Maitre, B.6
Volkmann, N.7
Hanein, D.8
Rouiller, I.9
Reed, J.C.10
-
39
-
-
79959732295
-
Nrf2 is essential for cholesterol crystalinduced inflammasome activation and exacerbation of atherosclerosis
-
Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev AT, Kisielow J, Hersberger M, Yamamoto M, Bachmann MF, and Kopf M. Nrf2 is essential for cholesterol crystalinduced inflammasome activation and exacerbation of atherosclerosis. Eur J Immunol 41: 2040-2051, 2011.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2040-2051
-
-
Freigang, S.1
Ampenberger, F.2
Spohn, G.3
Heer, S.4
Shamshiev, A.T.5
Kisielow, J.6
Hersberger, M.7
Yamamoto, M.8
Bachmann, M.F.9
Kopf, M.10
-
40
-
-
84886674980
-
Fatty acidinduced mitochondrial uncoupling elicits inflammasomeindependent IL-1alpha and sterile vascular inflammation in atherosclerosis
-
Freigang S, Ampenberger F, Weiss A, Kanneganti TD, Iwakura Y, Hersberger M, and Kopf M. Fatty acidinduced mitochondrial uncoupling elicits inflammasomeindependent IL-1alpha and sterile vascular inflammation in atherosclerosis. Nat Immunol 14: 1045-1053, 2013.
-
(2013)
Nat Immunol
, vol.14
, pp. 1045-1053
-
-
Freigang, S.1
Ampenberger, F.2
Weiss, A.3
Kanneganti, T.D.4
Iwakura, Y.5
Hersberger, M.6
Kopf, M.7
-
41
-
-
0038359740
-
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis
-
Fubini B and Hubbard A. Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation by silica in inflammation and fibrosis. Free Radic Biol Med 34: 1507-1516, 2003.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1507-1516
-
-
Fubini, B.1
Hubbard, A.2
-
42
-
-
84894583793
-
NADPH oxidase derived reactive oxygen species are involved in human neutrophil IL-1beta secretion but not in inflammasome activation
-
Gabelloni ML, Sabbione F, Jancic C, Bass JF, Keitelman I, Iula L, Oleastro M, Geffner JR, and Trevani AS. NADPH oxidase derived reactive oxygen species are involved in human neutrophil IL-1beta secretion but not in inflammasome activation. Eur J Immunol 43: 3324-3335, 2013.
-
(2013)
Eur J Immunol
, vol.43
, pp. 3324-3335
-
-
Gabelloni, M.L.1
Sabbione, F.2
Jancic, C.3
Bass, J.F.4
Keitelman, I.5
Iula, L.6
Oleastro, M.7
Geffner, J.R.8
Trevani, A.S.9
-
43
-
-
0001360461
-
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease
-
Griffin WS, Stanley LC, Ling C, White L, MacLeod V, Perrot LJ, White CL, 3rd, and Araoz C. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci U S A 86: 7611-7615, 1989.
-
(1989)
Proc Natl Acad Sci U S A
, vol.86
, pp. 7611-7615
-
-
Griffin, W.S.1
Stanley, L.C.2
Ling, C.3
White, L.4
Macleod, V.5
Perrot, L.J.6
White, C.L.7
Araoz, C.8
-
44
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, and Golenbock DT. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol 9: 857-865, 2008.
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
45
-
-
84867320879
-
Cutting edge: MiR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL- 1beta production
-
Haneklaus M, Gerlic M, Kurowska-Stolarska M, Rainey AA, Pich D, McInnes IB, Hammerschmidt W, O'Neill LA, and Masters SL. Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL- 1beta production. J Immunol 189: 3795-3799, 2012.
-
(2012)
J Immunol
, vol.189
, pp. 3795-3799
-
-
Haneklaus, M.1
Gerlic, M.2
Kurowska-Stolarska, M.3
Rainey, A.A.4
Pich, D.5
McInnes, I.B.6
Hammerschmidt, W.7
O'Neill, L.A.8
Masters, S.L.9
-
46
-
-
1042290321
-
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
-
Hawkins PN, Lachmann HJ, Aganna E, and McDermott MF. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 50: 607-612, 2004.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 607-612
-
-
Hawkins, P.N.1
Lachmann, H.J.2
Aganna, E.3
McDermott, M.F.4
-
47
-
-
84871514528
-
HMGB1 promotes the synthesis of pro-IL-1beta and pro- IL-18 by activation of p38 MAPK and NF-kappaB through receptors for advanced glycation end-products in macrophages
-
He Q, You H, Li XM, Liu TH, Wang P, and Wang BE. HMGB1 promotes the synthesis of pro-IL-1beta and pro- IL-18 by activation of p38 MAPK and NF-kappaB through receptors for advanced glycation end-products in macrophages. Asian Pac J Cancer Prev 13: 1365-1370, 2012.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 1365-1370
-
-
He, Q.1
You, H.2
Li, X.M.3
Liu, T.H.4
Wang, P.5
Wang, B.E.6
-
48
-
-
84856957894
-
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
-
Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, and Flavell RA. Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Nature 482: 179-185, 2012.
-
(2012)
Nature
, vol.482
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
Hao, L.4
Mehal, W.Z.5
Strowig, T.6
Thaiss, C.A.7
Kau, A.L.8
Eisenbarth, S.C.9
Jurczak, M.J.10
Camporez, J.P.11
Shulman, G.I.12
Gordon, J.I.13
Hoffman, H.M.14
Flavell, R.A.15
-
49
-
-
84858654981
-
Inflammasomes: Far beyond inflammation
-
Henao-Mejia J, Elinav E, Strowig T, and Flavell RA. Inflammasomes: far beyond inflammation. Nat Immunol 13: 321-324, 2012.
-
(2012)
Nat Immunol
, vol.13
, pp. 321-324
-
-
Henao-Mejia, J.1
Elinav, E.2
Strowig, T.3
Flavell, R.A.4
-
50
-
-
84873087532
-
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
-
Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, and Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature 493: 674-678, 2013.
-
(2013)
Nature
, vol.493
, pp. 674-678
-
-
Heneka, M.T.1
Kummer, M.P.2
Stutz, A.3
Delekate, A.4
Schwartz, S.5
Vieira-Saecker, A.6
Griep, A.7
Axt, D.8
Remus, A.9
Tzeng, T.C.10
Gelpi, E.11
Halle, A.12
Korte, M.13
Latz, E.14
Golenbock, D.T.15
-
51
-
-
50249090764
-
A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes
-
Hewinson J, Moore SF, Glover C, Watts AG, and MacKenzie AB. A key role for redox signaling in rapid P2X7 receptor-induced IL-1 beta processing in human monocytes. J Immunol 180: 8410-8420, 2008.
-
(2008)
J Immunol
, vol.180
, pp. 8410-8420
-
-
Hewinson, J.1
Moore, S.F.2
Glover, C.3
Watts, A.G.4
Mackenzie, A.B.5
-
52
-
-
79751493607
-
Linking the inflammasome to obesity-related disease
-
Horng T and Hotamisligil GS. Linking the inflammasome to obesity-related disease. Nat Med 17: 164-165, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 164-165
-
-
Horng, T.1
Hotamisligil, G.S.2
-
53
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, and Latz E. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 9: 847-856, 2008.
-
(2008)
Nat Immunol
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
54
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140: 900-917, 2010.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
55
-
-
60549112774
-
Inflammasome recognition of influenza virus is essential for adaptive immune responses
-
Ichinohe T, Lee HK, Ogura Y, Flavell R, and Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 206: 79-87, 2009.
-
(2009)
J Exp Med
, vol.206
, pp. 79-87
-
-
Ichinohe, T.1
Lee, H.K.2
Ogura, Y.3
Flavell, R.4
Iwasaki, A.5
-
56
-
-
73949118676
-
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome
-
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, and Sutterwala FS. Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. Proc Natl Acad Sci U S A 106: 20388-20393, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20388-20393
-
-
Iyer, S.S.1
Pulskens, W.P.2
Sadler, J.J.3
Butter, L.M.4
Teske, G.J.5
Ulland, T.K.6
Eisenbarth, S.C.7
Florquin, S.8
Flavell, R.A.9
Leemans, J.C.10
Sutterwala, F.S.11
-
57
-
-
79960427714
-
Lipid raft redox signaling: Molecular mechanisms in health and disease
-
Jin S, Zhou F, Katirai F, and Li PL. Lipid raft redox signaling: molecular mechanisms in health and disease. Antioxid Redox Signal 15: 1043-1083, 2011.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 1043-1083
-
-
Jin, S.1
Zhou, F.2
Katirai, F.3
Li, P.L.4
-
58
-
-
39849096995
-
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223
-
Johnnidis JB, Harris MH, Wheeler RT, Stehling-Sun S, Lam MH, Kirak O, Brummelkamp TR, Fleming MD, and Camargo FD. Regulation of progenitor cell proliferation and granulocyte function by microRNA-223. Nature 451: 1125-1129, 2008.
-
(2008)
Nature
, vol.451
, pp. 1125-1129
-
-
Johnnidis, J.B.1
Harris, M.H.2
Wheeler, R.T.3
Stehling-Sun, S.4
Lam, M.H.5
Kirak, O.6
Brummelkamp, T.R.7
Fleming, M.D.8
Camargo, F.D.9
-
59
-
-
70349317039
-
Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
-
Joly S, Ma N, Sadler JJ, Soll DR, Cassel SL, and Sutterwala FS. Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome. J Immunol 183: 3578-3581, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 3578-3581
-
-
Joly, S.1
Ma, N.2
Sadler, J.J.3
Soll, D.R.4
Cassel, S.L.5
Sutterwala, F.S.6
-
60
-
-
84867770402
-
Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation
-
Juliana C, Fernandes-Alnemri T, Kang S, Farias A, Qin F, and Alnemri ES. Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation. J Biol Chem 287: 36617-36622, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 36617-36622
-
-
Juliana, C.1
Fernandes-Alnemri, T.2
Kang, S.3
Farias, A.4
Qin, F.5
Alnemri, E.S.6
-
61
-
-
4243897255
-
Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy
-
Khan N and Swartz H. Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy. Mol Cell Biochem 234-235: 341-357, 2002.
-
(2002)
Mol Cell Biochem
, vol.234-235
, pp. 341-357
-
-
Khan, N.1
Swartz, H.2
-
62
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM and Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477: 592-595, 2011.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
63
-
-
84864812784
-
NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice
-
Kovarova M, Hesker PR, Jania L, Nguyen M, Snouwaert JN, Xiang Z, Lommatzsch SE, Huang MT, Ting JP, and Koller BH. NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice. J Immunol 189: 2006-2016, 2012.
-
(2012)
J Immunol
, vol.189
, pp. 2006-2016
-
-
Kovarova, M.1
Hesker, P.R.2
Jania, L.3
Nguyen, M.4
Snouwaert, J.N.5
Xiang, Z.6
Lommatzsch, S.E.7
Huang, M.T.8
Ting, J.P.9
Koller, B.H.10
-
64
-
-
84905660109
-
Emerging concepts about NAIP/NLRC4 inflammasomes
-
Lage SL, Longo C, Branco LM, da Costa TB, Buzzo Cde L, and Bortoluci KR. Emerging Concepts about NAIP/NLRC4 Inflammasomes. Front Immunol 5: 309, 2014.
-
(2014)
Front Immunol
, vol.5
, pp. 309
-
-
Lage, S.L.1
Longo, C.2
Branco, L.M.3
Da Costa, T.B.4
Buzzo Cde, L.5
Bortoluci, K.R.6
-
65
-
-
79952159132
-
Emerging inflammasome effector mechanisms
-
Lamkanfi M. Emerging inflammasome effector mechanisms. Nat Rev Immunol 11: 213-220, 2011.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 213-220
-
-
Lamkanfi, M.1
-
66
-
-
84864682160
-
IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
-
Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, and Papa FR. IRE1alpha induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab 16: 250-264, 2012.
-
(2012)
Cell Metab
, vol.16
, pp. 250-264
-
-
Lerner, A.G.1
Upton, J.P.2
Praveen, P.V.3
Ghosh, R.4
Nakagawa, Y.5
Igbaria, A.6
Shen, S.7
Nguyen, V.8
Backes, B.J.9
Heiman, M.10
Heintz, N.11
Greengard, P.12
Hui, S.13
Tang, Q.14
Trusina, A.15
Oakes, S.A.16
Papa, F.R.17
-
67
-
-
34547897044
-
Lipid raft redox signaling platforms in endothelial dysfunction
-
Li PL, Zhang Y, and Yi F. Lipid raft redox signaling platforms in endothelial dysfunction. Antioxid Redox Signal 9: 1457-1470, 2007.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1457-1470
-
-
Li, P.L.1
Zhang, Y.2
Yi, F.3
-
68
-
-
84898470805
-
The role of the inflammasome in cardiovascular diseases
-
Li X, Deroide N, and Mallat Z. The role of the inflammasome in cardiovascular diseases. J Mol Med (Berl) 92: 307-319, 2014.
-
(2014)
J Mol Med (Berl)
, vol.92
, pp. 307-319
-
-
Li, X.1
Deroide, N.2
Mallat, Z.3
-
69
-
-
84900301850
-
Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: Implication of a novel role of inflammasome in atherogenesis
-
Li X, Zhang Y, Xia M, Gulbins E, Boini KM, and Li PL. Activation of Nlrp3 inflammasomes enhances macrophage lipid-deposition and migration: implication of a novel role of inflammasome in atherogenesis. PLoS One 9: e87552, 2014.
-
(2014)
PLoS One
, vol.9
-
-
Li, X.1
Zhang, Y.2
Xia, M.3
Gulbins, E.4
Boini, K.M.5
Li, P.L.6
-
70
-
-
84872290052
-
Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase- 1-mediated interleukin-1beta secretion
-
Liao PC, Chao LK, Chou JC, Dong WC, Lin CN, Lin CY, Chen A, Ka SM, Ho CL, and Hua KF. Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase- 1-mediated interleukin-1beta secretion. Inflamm Res 62: 89-96, 2013.
-
(2013)
Inflamm Res
, vol.62
, pp. 89-96
-
-
Liao, P.C.1
Chao, L.K.2
Chou, J.C.3
Dong, W.C.4
Lin, C.N.5
Lin, C.Y.6
Chen, A.7
Ka, S.M.8
Ho, C.L.9
Hua, K.F.10
-
71
-
-
79953315378
-
Differential requirements for NAIP5 in activation of the NLRC4 inflammasome
-
Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, and Vance RE. Differential requirements for NAIP5 in activation of the NLRC4 inflammasome. Infect Immun 79: 1606-1614, 2011.
-
(2011)
Infect Immun
, vol.79
, pp. 1606-1614
-
-
Lightfield, K.L.1
Persson, J.2
Trinidad, N.J.3
Brubaker, S.W.4
Kofoed, E.M.5
Sauer, J.D.6
Dunipace, E.A.7
Warren, S.E.8
Miao, E.A.9
Vance, R.E.10
-
72
-
-
79952076264
-
Ricin toxin activates the NALP3 inflammasome
-
Lindauer M, Wong J, and Magun B. Ricin toxin activates the NALP3 inflammasome. Toxins (Basel) 2: 1500-1514, 2010.
-
(2010)
Toxins (Basel)
, vol.2
, pp. 1500-1514
-
-
Lindauer, M.1
Wong, J.2
Magun, B.3
-
73
-
-
84873834109
-
Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome
-
Lopez-Castejon G, Luheshi NM, Compan V, High S, Whitehead RC, Flitsch S, Kirov A, Prudovsky I, Swanton E, and Brough D. Deubiquitinases regulate the activity of caspase-1 and interleukin-1beta secretion via assembly of the inflammasome. J Biol Chem 288: 2721-2733, 2013.
-
(2013)
J Biol Chem
, vol.288
, pp. 2721-2733
-
-
Lopez-Castejon, G.1
Luheshi, N.M.2
Compan, V.3
High, S.4
Whitehead, R.C.5
Flitsch, S.6
Kirov, A.7
Prudovsky, I.8
Swanton, E.9
Brough, D.10
-
74
-
-
84876685141
-
Receptor interacting protein kinase 2- mediated mitophagy regulates inflammasome activation during virus infection
-
Lupfer C, Thomas PG, Anand PK, Vogel P, Milasta S, Martinez J, Huang G, Green M, Kundu M, Chi H, Xavier RJ, Green DR, Lamkanfi M, Dinarello CA, Doherty PC, and Kanneganti TD. Receptor interacting protein kinase 2- mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol 14: 480-488, 2013.
-
(2013)
Nat Immunol
, vol.14
, pp. 480-488
-
-
Lupfer, C.1
Thomas, P.G.2
Anand, P.K.3
Vogel, P.4
Milasta, S.5
Martinez, J.6
Huang, G.7
Green, M.8
Kundu, M.9
Chi, H.10
Xavier, R.J.11
Green, D.R.12
Lamkanfi, M.13
Dinarello, C.A.14
Doherty, P.C.15
Kanneganti, T.D.16
-
75
-
-
34247165763
-
ASC Ipaf and Cryopyrin/Nalp3: Bona fide intracellular adapters of the caspase-1 inflammasome
-
Mariathasan S. ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome. Microbes Infect 9: 664-671, 2007.
-
(2007)
Microbes Infect
, vol.9
, pp. 664-671
-
-
Mariathasan, S.1
-
76
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O'Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, and Dixit VM. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232, 2006.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
77
-
-
77749304032
-
Signaling by ROS drives inflammasome activation
-
Martinon F. Signaling by ROS drives inflammasome activation. Eur J Immunol 40: 616-619, 2010.
-
(2010)
Eur J Immunol
, vol.40
, pp. 616-619
-
-
Martinon, F.1
-
78
-
-
7944232105
-
Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome
-
Martinon F, Agostini L, Meylan E, and Tschopp J. Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr Biol 14: 1929-1934, 2004.
-
(2004)
Curr Biol
, vol.14
, pp. 1929-1934
-
-
Martinon, F.1
Agostini, L.2
Meylan, E.3
Tschopp, J.4
-
79
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, and Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426, 2002.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
80
-
-
32944468985
-
Gout-associated uric acid crystals activate the NALP3 inflammasome
-
Martinon F, Petrilli V, Mayor A, Tardivel A, and Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440: 237-241, 2006.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, J.5
-
81
-
-
22444433175
-
NLRs join TLRs as innate sensors of pathogens
-
Martinon F and Tschopp J. NLRs join TLRs as innate sensors of pathogens. Trends Immunol 26: 447-454, 2005.
-
(2005)
Trends Immunol
, vol.26
, pp. 447-454
-
-
Martinon, F.1
Tschopp, J.2
-
82
-
-
84882285470
-
Specific inflammasomes in complex diseases
-
Masters SL. Specific inflammasomes in complex diseases. Clin Immunol 147: 223-228, 2013.
-
(2013)
Clin Immunol
, vol.147
, pp. 223-228
-
-
Masters, S.L.1
-
83
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, and O'Neill LA. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes. Nat Immunol 11: 897-904, 2010.
-
(2010)
Nat Immunol
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.15
Mok, K.H.16
Newsholme, P.17
Nunez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.22
more..
-
84
-
-
0034939382
-
Elevated interleukin-18 levels in the urine of nephrotic patients
-
Matsumoto K and Kanmatsuse K. Elevated interleukin-18 levels in the urine of nephrotic patients. Nephron 88: 334-339, 2001.
-
(2001)
Nephron
, vol.88
, pp. 334-339
-
-
Matsumoto, K.1
Kanmatsuse, K.2
-
85
-
-
47849120473
-
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
-
Meissner F, Molawi K, and Zychlinsky A. Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat Immunol 9: 866-872, 2008.
-
(2008)
Nat Immunol
, vol.9
, pp. 866-872
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
-
86
-
-
77956601381
-
Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease
-
Meissner F, Seger RA, Moshous D, Fischer A, Reichenbach J, and Zychlinsky A. Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease. Blood 116: 1570-1573, 2010.
-
(2010)
Blood
, vol.116
, pp. 1570-1573
-
-
Meissner, F.1
Seger, R.A.2
Moshous, D.3
Fischer, A.4
Reichenbach, J.5
Zychlinsky, A.6
-
87
-
-
84856857478
-
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway
-
Menu P, Mayor A, Zhou R, Tardivel A, Ichijo H, Mori K, and Tschopp J. ER stress activates the NLRP3 inflammasome via an UPR-independent pathway. Cell Death Dis 3: e261, 2012.
-
(2012)
Cell Death Dis
, vol.3
, pp. e261
-
-
Menu, P.1
Mayor, A.2
Zhou, R.3
Tardivel, A.4
Ichijo, H.5
Mori, K.6
Tschopp, J.7
-
88
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, Leaf IA, and Aderem A. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci U S A 107: 3076-3080, 2010.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
Leaf, I.A.7
Aderem, A.8
-
89
-
-
84893663061
-
Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet
-
Mohamed IN, Hafez SS, Fairaq A, Ergul A, Imig JD, and El-Remessy AB. Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet. Diabetologia 57: 413-423, 2014.
-
(2014)
Diabetologia
, vol.57
, pp. 413-423
-
-
Mohamed, I.N.1
Hafez, S.S.2
Fairaq, A.3
Ergul, A.4
Imig, J.D.5
El-Remessy, A.B.6
-
90
-
-
0035209916
-
Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1
-
Monack DM, Detweiler CS, and Falkow S. Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1. Cell Microbiol 3: 825-837, 2001.
-
(2001)
Cell Microbiol
, vol.3
, pp. 825-837
-
-
Monack, D.M.1
Detweiler, C.S.2
Falkow, S.3
-
91
-
-
73649189052
-
Wellsm. Urticaria deafness, and amyloidosis: A new heredo-familial syndrome
-
Muckle TJ, Wellsm. Urticaria, deafness, and amyloidosis: a new heredo-familial syndrome. Q J Med 31: 235-248, 1962.
-
(1962)
Q J Med
, vol.31
, pp. 235-248
-
-
Muckle, T.J.1
-
92
-
-
84903768213
-
GSK's darapladib failures dim hopes for antiinflammatory heart drugs
-
Mullard A. GSK's darapladib failures dim hopes for antiinflammatory heart drugs. Nat Rev Drug Discov 13: 481-482, 2014.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 481-482
-
-
Mullard, A.1
-
93
-
-
84879596906
-
K(+) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter
-
Munoz-Planillo R, Kuffa P, Martinez-Colon G, Smith BL, Rajendiran TM, and Nunez G. K( + ) efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. Immunity 38: 1142-1153, 2013.
-
(2013)
Immunity
, vol.38
, pp. 1142-1153
-
-
Munoz-Planillo, R.1
Kuffa, P.2
Martinez-Colon, G.3
Smith, B.L.4
Rajendiran, T.M.5
Nunez, G.6
-
94
-
-
84863978096
-
Critical role for calcium mobilization in activation of the NLRP3 inflammasome
-
Murakami T, Ockinger J, Yu J, Byles V, McColl A, Hofer AM, and Horng T. Critical role for calcium mobilization in activation of the NLRP3 inflammasome. Proc Natl Acad Sci U S A 109: 11282-11287, 2012.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11282-11287
-
-
Murakami, T.1
Ockinger, J.2
Yu, J.3
Byles, V.4
McColl, A.5
Hofer, A.M.6
Horng, T.7
-
95
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, Parks RJ, and Tschopp J. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature 452: 103-107, 2008.
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
Parks, R.J.7
Tschopp, J.8
-
96
-
-
12144288979
-
Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID MWS, and FCU
-
Neven B, Callebaut I, Prieur AM, Feldmann J, Bodemer C, Lepore L, Derfalvi B, Benjaponpitak S, Vesely R, Sauvain MJ, Oertle S, Allen R, Morgan G, Borkhardt A, Hill C, Gardner-Medwin J, Fischer A, and de Saint Basile G. Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU. Blood 103: 2809-2815, 2004.
-
(2004)
Blood
, vol.103
, pp. 2809-2815
-
-
Neven, B.1
Callebaut, I.2
Prieur, A.M.3
Feldmann, J.4
Bodemer, C.5
Lepore, L.6
Derfalvi, B.7
Benjaponpitak, S.8
Vesely, R.9
Sauvain, M.J.10
Oertle, S.11
Allen, R.12
Morgan, G.13
Borkhardt, A.14
Hill, C.15
Gardner-Medwin, J.16
Fischer, A.17
De Saint Basile, G.18
-
97
-
-
78650988141
-
Involvement of xanthine oxidase and hypoxiainducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta
-
Nicholas SA, Bubnov VV, Yasinska IM, and Sumbayev VV. Involvement of xanthine oxidase and hypoxiainducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1beta. Cell Mol Life Sci 68: 151-158, 2011.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 151-158
-
-
Nicholas, S.A.1
Bubnov, V.V.2
Yasinska, I.M.3
Sumbayev, V.V.4
-
98
-
-
8544275794
-
Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides
-
Niemir ZI, Stein H, Dworacki G, Mundel P, Koehl N, Koch B, Autschbach F, Andrassy K, Ritz E, Waldherr R, and Otto HF. Podocytes are the major source of IL-1 alpha and IL-1 beta in human glomerulonephritides. Kidney Int 52: 393-403, 1997.
-
(1997)
Kidney Int
, vol.52
, pp. 393-403
-
-
Niemir, Z.I.1
Stein, H.2
Dworacki, G.3
Mundel, P.4
Koehl, N.5
Koch, B.6
Autschbach, F.7
Andrassy, K.8
Ritz, E.9
Waldherr, R.10
Otto, H.F.11
-
99
-
-
84875730197
-
Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status
-
Nishi Y, Satoh M, Nagasu H, Kadoya H, Ihoriya C, Kidokoro K, Sasaki T, and Kashihara N. Selective estrogen receptor modulation attenuates proteinuria-induced renal tubular damage by modulating mitochondrial oxidative status. Kidney Int 83: 662-673, 2013.
-
(2013)
Kidney Int
, vol.83
, pp. 662-673
-
-
Nishi, Y.1
Satoh, M.2
Nagasu, H.3
Kadoya, H.4
Ihoriya, C.5
Kidokoro, K.6
Sasaki, T.7
Kashihara, N.8
-
100
-
-
0346350694
-
Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties
-
O'Connor W, Jr., Harton JA, Zhu X, Linhoff MW, and Ting JP. Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties. J Immunol 171: 6329-6333, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 6329-6333
-
-
O'Connor, W.1
Harton, J.A.2
Zhu, X.3
Linhoff, M.W.4
Ting, J.P.5
-
101
-
-
84864693470
-
Thioredoxin- interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome
-
Oslowski CM, Hara T, O'Sullivan-Murphy B, Kanekura K, Lu S, Hara M, Ishigaki S, Zhu LJ, Hayashi E, Hui ST, Greiner D, Kaufman RJ, Bortell R, and Urano F. Thioredoxin- interacting protein mediates ER stress-induced beta cell death through initiation of the inflammasome. Cell Metab 16: 265-273, 2012.
-
(2012)
Cell Metab
, vol.16
, pp. 265-273
-
-
Oslowski, C.M.1
Hara, T.2
O'Sullivan-Murphy, B.3
Kanekura, K.4
Lu, S.5
Hara, M.6
Ishigaki, S.7
Zhu, L.J.8
Hayashi, E.9
Hui, S.T.10
Greiner, D.11
Kaufman, R.J.12
Bortell, R.13
Urano, F.14
-
102
-
-
84897498263
-
Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer
-
Overley-Adamson B, Artlett CM, Stephens C, Sassi-Gaha S, Weis RD, and Thacker JD. Targeting the unfolded protein response, XBP1, and the NLRP3 inflammasome in fibrosis and cancer. Cancer Biol Ther 15, 420-462, 2014.
-
(2014)
Cancer Biol Ther
, vol.15
, pp. 420-462
-
-
Overley-Adamson, B.1
Artlett, C.M.2
Stephens, C.3
Sassi-Gaha, S.4
Weis, R.D.5
Thacker, J.D.6
-
103
-
-
84885437002
-
The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
-
Park S, Juliana C, Hong S, Datta P, Hwang I, Fernandes- Alnemri T, Yu JW, and Alnemri ES. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity. J Immunol 191: 4358-4366, 2013.
-
(2013)
J Immunol
, vol.191
, pp. 4358-4366
-
-
Park, S.1
Juliana, C.2
Hong, S.3
Datta, P.4
Hwang, I.5
Fernandes-Alnemri, T.6
Yu, J.W.7
Alnemri, E.S.8
-
104
-
-
33750473352
-
Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor
-
Pelegrin P and Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATPgated P2X7 receptor. EMBO J 25: 5071-5082, 2006.
-
(2006)
EMBO J
, vol.25
, pp. 5071-5082
-
-
Pelegrin, P.1
Surprenant, A.2
-
105
-
-
67651172779
-
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates
-
Pelegrin P and Surprenant A. Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates. EMBO J 28: 2114-2127, 2009.
-
(2009)
EMBO J
, vol.28
, pp. 2114-2127
-
-
Pelegrin, P.1
Surprenant, A.2
-
106
-
-
36849095530
-
The inflammasome, autoinflammatory diseases, and gout
-
Petrilli V and Martinon F. The inflammasome, autoinflammatory diseases, and gout. Joint Bone Spine 74: 571-576, 2007.
-
(2007)
Joint Bone Spine
, vol.74
, pp. 571-576
-
-
Petrilli, V.1
Martinon, F.2
-
107
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, and Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14: 1583-1589, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
108
-
-
77649275621
-
ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function
-
Pi J, Zhang Q, Fu J, Woods CG, Hou Y, Corkey BE, Collins S, and Andersen ME. ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. Toxicol Appl Pharmacol 244: 77-83, 2010.
-
(2010)
Toxicol Appl Pharmacol
, vol.244
, pp. 77-83
-
-
Pi, J.1
Zhang, Q.2
Fu, J.3
Woods, C.G.4
Hou, Y.5
Corkey, B.E.6
Collins, S.7
Andersen, M.E.8
-
109
-
-
54149111582
-
Homocysteine up-regulates vascular transmembrane chemokine CXCL16 and induces CXCR6 + lymphocyte recruitment in vitro and in vivo
-
Postea O, Koenen RR, Hristov M, Weber C, and Ludwig A. Homocysteine up-regulates vascular transmembrane chemokine CXCL16 and induces CXCR6 + lymphocyte recruitment in vitro and in vivo. J Cell Mol Med 12: 1700-1709, 2008.
-
(2008)
J Cell Mol Med
, vol.12
, pp. 1700-1709
-
-
Postea, O.1
Koenen, R.R.2
Hristov, M.3
Weber, C.4
Ludwig, A.5
-
110
-
-
84872782298
-
Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity
-
Py BF, Kim MS, Vakifahmetoglu-Norberg H, and Yuan J. Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity. Mol Cell 49: 331-338, 2013.
-
(2013)
Mol Cell
, vol.49
, pp. 331-338
-
-
Py, B.F.1
Kim, M.S.2
Vakifahmetoglu-Norberg, H.3
Yuan, J.4
-
111
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, Hardy LL, Garceau V, Sweet MJ, Ross IL, Hume DA, and Stacey KJ. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science 323: 1057-1060, 2009.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
Hardy, L.L.7
Garceau, V.8
Sweet, M.J.9
Ross, I.L.10
Hume, D.A.11
Stacey, K.J.12
-
112
-
-
84870781498
-
Phospholipase A2 enzymes and the risk of atherosclerosis
-
Rosenson RS and Hurt-Camejo E. Phospholipase A2 enzymes and the risk of atherosclerosis. Eur Heart J 33: 2899-2909, 2012.
-
(2012)
Eur Heart J
, vol.33
, pp. 2899-2909
-
-
Rosenson, R.S.1
Hurt-Camejo, E.2
-
113
-
-
84897491455
-
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release
-
Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappegard KT, Brekke OL, Lambris JD, Damas JK, Latz E, Mollnes TE, and Espevik T. Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol 192: 2837-2845, 2014.
-
(2014)
J Immunol
, vol.192
, pp. 2837-2845
-
-
Samstad, E.O.1
Niyonzima, N.2
Nymo, S.3
Aune, M.H.4
Ryan, L.5
Bakke, S.S.6
Lappegard, K.T.7
Brekke, O.L.8
Lambris, J.D.9
Damas, J.K.10
Latz, E.11
Mollnes, T.E.12
Espevik, T.13
-
114
-
-
0034101762
-
Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats
-
Sassy-Prigent C, Heudes D, Mandet C, Belair MF, Michel O, Perdereau B, Bariety J, and Bruneval P. Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats. Diabetes 49: 466-475, 2000.
-
(2000)
Diabetes
, vol.49
, pp. 466-475
-
-
Sassy-Prigent, C.1
Heudes, D.2
Mandet, C.3
Belair, M.F.4
Michel, O.5
Perdereau, B.6
Bariety, J.7
Bruneval, P.8
-
115
-
-
37549002511
-
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
-
Shao W, Yeretssian G, Doiron K, Hussain SN, and Saleh M. The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 282: 36321-36329, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 36321-36329
-
-
Shao, W.1
Yeretssian, G.2
Doiron, K.3
Hussain, S.N.4
Saleh, M.5
-
116
-
-
84862777872
-
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis
-
Shimada K, Crother TR, Karlin J, Dagvadorj J, Chiba N, Chen S, Ramanujan VK, Wolf AJ, Vergnes L, Ojcius DM, Rentsendorj A, Vargas M, Guerrero C, Wang Y, Fitzgerald KA, Underhill DM, Town T, and Arditi M. Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. Immunity 36: 401-414, 2012.
-
(2012)
Immunity
, vol.36
, pp. 401-414
-
-
Shimada, K.1
Crother, T.R.2
Karlin, J.3
Dagvadorj, J.4
Chiba, N.5
Chen, S.6
Ramanujan, V.K.7
Wolf, A.J.8
Vergnes, L.9
Ojcius, D.M.10
Rentsendorj, A.11
Vargas, M.12
Guerrero, C.13
Wang, Y.14
Fitzgerald, K.A.15
Underhill, D.M.16
Town, T.17
Arditi, M.18
-
117
-
-
40649094344
-
Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells
-
Silva JP, Proenca F, and Coutinho OP. Protective role of new nitrogen compounds on ROS/RNS-mediated damage to PC12 cells. Free Radic Res 42: 57-69, 2008.
-
(2008)
Free Radic Res
, vol.42
, pp. 57-69
-
-
Silva, J.P.1
Proenca, F.2
Coutinho, O.P.3
-
118
-
-
78649498271
-
The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity
-
Stienstra R, Joosten LA, Koenen T, van Tits B, van Diepen JA, van den Berg SA, Rensen PC, Voshol PJ, Fantuzzi G, Hijmans A, Kersten S, Muller M, van den Berg WB, van Rooijen N, Wabitsch M, Kullberg BJ, van der Meer JW, Kanneganti T, Tack CJ, and Netea MG. The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. Cell Metab 12: 593-605, 2010.
-
(2010)
Cell Metab
, vol.12
, pp. 593-605
-
-
Stienstra, R.1
Joosten, L.A.2
Koenen, T.3
Van Tits, B.4
Van Diepen, J.A.5
Van Den Berg, S.A.6
Rensen, P.C.7
Voshol, P.J.8
Fantuzzi, G.9
Hijmans, A.10
Kersten, S.11
Muller, M.12
Van Den Berg, W.B.13
Van Rooijen, N.14
Wabitsch, M.15
Kullberg, B.J.16
Van Der Meer, J.W.17
Kanneganti, T.18
Tack, C.J.19
Netea, M.G.20
more..
-
119
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, and Kanneganti TD. Inflammasome is a central player in the induction of obesity and insulin resistance. Proc Natl Acad Sci U S A 108: 15324-15329, 2011.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
Zaki, M.H.4
Van De Veerdonk, F.L.5
Perera, D.6
Neale, G.A.7
Hooiveld, G.J.8
Hijmans, A.9
Vroegrijk, I.10
Van Den Berg, S.11
Romijn, J.12
Rensen, P.C.13
Joosten, L.A.14
Netea, M.G.15
Kanneganti, T.D.16
-
120
-
-
84876237736
-
The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
-
Subramanian N, Natarajan K, Clatworthy MR, Wang Z, and Germain RN. The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation. Cell 153: 348-361, 2013.
-
(2013)
Cell
, vol.153
, pp. 348-361
-
-
Subramanian, N.1
Natarajan, K.2
Clatworthy, M.R.3
Wang, Z.4
Germain, R.N.5
-
121
-
-
0029665112
-
The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
-
Surprenant A, Rassendren F, Kawashima E, North RA, and Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science 272: 735-738, 1996.
-
(1996)
Science
, vol.272
, pp. 735-738
-
-
Surprenant, A.1
Rassendren, F.2
Kawashima, E.3
North, R.A.4
Buell, G.5
-
122
-
-
34547743231
-
The inflammasome in pathogen recognition and inflammation
-
Sutterwala FS, Ogura Y, and Flavell RA. The inflammasome in pathogen recognition and inflammation. J Leukoc Biol 82: 259-264, 2007.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 259-264
-
-
Sutterwala, F.S.1
Ogura, Y.2
Flavell, R.A.3
-
123
-
-
84860792654
-
Role of the inflammasome in myocardial infarction
-
Takahashi M. Role of the inflammasome in myocardial infarction. Trends Cardiovasc Med 21: 37-41, 2011.
-
(2011)
Trends Cardiovasc Med
, vol.21
, pp. 37-41
-
-
Takahashi, M.1
-
124
-
-
70249117528
-
Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response
-
Tassi S, Carta S, Vene R, Delfino L, Ciriolo MR, and Rubartelli A. Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response. J Immunol 183: 1456-1462, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 1456-1462
-
-
Tassi, S.1
Carta, S.2
Vene, R.3
Delfino, L.4
Ciriolo, M.R.5
Rubartelli, A.6
-
125
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR, Jr., Ellebedy AH, Reynolds C, Funk AJ, Martin WJ, Lamkanfi M, Webby RJ, Boyd KL, Doherty PC, and Kanneganti TD. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30: 566-575, 2009.
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge, J.R.3
Ellebedy, A.H.4
Reynolds, C.5
Funk, A.J.6
Martin, W.J.7
Lamkanfi, M.8
Webby, R.J.9
Boyd, K.L.10
Doherty, P.C.11
Kanneganti, T.D.12
-
126
-
-
84880651157
-
The complement membrane attack complex triggers intracellular Ca2 + fluxes leading to NLRP3 inflammasome activation
-
Triantafilou K, Hughes TR, Triantafilou M, and Morgan BP. The complement membrane attack complex triggers intracellular Ca2 + fluxes leading to NLRP3 inflammasome activation. J Cell Sci 126: 2903-2913, 2013.
-
(2013)
J Cell Sci
, vol.126
, pp. 2903-2913
-
-
Triantafilou, K.1
Hughes, T.R.2
Triantafilou, M.3
Morgan, B.P.4
-
127
-
-
77649179433
-
NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
-
Tschopp J and Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 10: 210-215, 2010.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 210-215
-
-
Tschopp, J.1
Schroder, K.2
-
128
-
-
77955867246
-
Human NLRP3 inflammasome activation is Nox1-4 independent
-
van Bruggen R, Koker MY, Jansen M, van Houdt M, Roos D, Kuijpers TW, and van den Berg TK. Human NLRP3 inflammasome activation is Nox1-4 independent. Blood 115: 5398-5400, 2010.
-
(2010)
Blood
, vol.115
, pp. 5398-5400
-
-
Van Bruggen, R.1
Koker, M.Y.2
Jansen, M.3
Van Houdt, M.4
Roos, D.5
Kuijpers, T.W.6
Van Den Berg, T.K.7
-
129
-
-
77649260429
-
Reactive oxygen species-independent activation of the IL- 1beta inflammasome in cells from patients with chronic granulomatous disease
-
van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, van der Meer JW, and Netea MG. Reactive oxygen species-independent activation of the IL- 1beta inflammasome in cells from patients with chronic granulomatous disease. Proc Natl Acad Sci U S A 107: 3030-3033, 2010.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 3030-3033
-
-
Van De Veerdonk, F.L.1
Smeekens, S.P.2
Joosten, L.A.3
Kullberg, B.J.4
Dinarello, C.A.5
Van Der Meer, J.W.6
Netea, M.G.7
-
130
-
-
79751512463
-
The NLRP3 inflammasome instigates obesityinduced inflammation and insulin resistance
-
Vandanmagsar B, Youm YH, Ravussin A, Galgani JE, Stadler K, Mynatt RL, Ravussin E, Stephens JM, and Dixit VD. The NLRP3 inflammasome instigates obesityinduced inflammation and insulin resistance. Nat Med 17: 179-188, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
131
-
-
77957887259
-
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD
-
Vilaysane A, Chun J, Seamone ME, Wang W, Chin R, Hirota S, Li Y, Clark SA, Tschopp J, Trpkov K, Hemmelgarn BR, Beck PL, and Muruve DA. The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol 21: 1732-1744, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1732-1744
-
-
Vilaysane, A.1
Chun, J.2
Seamone, M.E.3
Wang, W.4
Chin, R.5
Hirota, S.6
Li, Y.7
Clark, S.A.8
Tschopp, J.9
Trpkov, K.10
Hemmelgarn, B.R.11
Beck, P.L.12
Muruve, D.A.13
-
132
-
-
84867063450
-
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
-
von Moltke J, Trinidad NJ, Moayeri M, Kintzer AF, Wang SB, van Rooijen N, Brown CR, Krantz BA, Leppla SH, Gronert K, and Vance RE. Rapid induction of inflammatory lipid mediators by the inflammasome in vivo. Nature 490: 107-111, 2012.
-
(2012)
Nature
, vol.490
, pp. 107-111
-
-
Von Moltke, J.1
Trinidad, N.J.2
Moayeri, M.3
Kintzer, A.F.4
Wang, S.B.5
Van Rooijen, N.6
Brown, C.R.7
Krantz, B.A.8
Leppla, S.H.9
Gronert, K.10
Vance, R.E.11
-
133
-
-
84862235344
-
Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation
-
Wang C, Pan Y, Zhang QY, Wang FM, and Kong LD. Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation. PLoS One 7: e38285, 2012.
-
(2012)
PLoS One
, vol.7
-
-
Wang, C.1
Pan, Y.2
Zhang, Q.Y.3
Wang, F.M.4
Kong, L.D.5
-
134
-
-
0036847780
-
Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: Role of chemokine and adhesion molecules
-
Wang G, Woo CW, Sung FL, Siow YL, and O K. Increased monocyte adhesion to aortic endothelium in rats with hyperhomocysteinemia: role of chemokine and adhesion molecules. Arterioscler Thromb Vasc Biol 22: 1777-1783, 2002.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 1777-1783
-
-
Wang, G.1
Woo, C.W.2
Sung, F.L.3
Siow, Y.L.4
-
135
-
-
67349106386
-
Protection by tetrahydroxystilbene glucoside against cerebral ischemia: Involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation
-
Wang T, Gu J, Wu PF, Wang F, Xiong Z, Yang YJ, Wu WN, Dong LD, and Chen JG. Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. Free Radic Biol Med 47: 229-240, 2009.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 229-240
-
-
Wang, T.1
Gu, J.2
Wu, P.F.3
Wang, F.4
Xiong, Z.5
Yang, Y.J.6
Wu, W.N.7
Dong, L.D.8
Chen, J.G.9
-
136
-
-
84879357128
-
Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
-
Wang W, Wang C, Ding XQ, Pan Y, Gu TT, Wang MX, Liu YL, Wang FM, Wang SJ, and Kong LD. Quercetin and allopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats. Br J Pharmacol 169: 1352-1371, 2013.
-
(2013)
Br J Pharmacol
, vol.169
, pp. 1352-1371
-
-
Wang, W.1
Wang, C.2
Ding, X.Q.3
Pan, Y.4
Gu, T.T.5
Wang, M.X.6
Liu, Y.L.7
Wang, F.M.8
Wang, S.J.9
Kong, L.D.10
-
137
-
-
84872737232
-
Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium
-
Wang W, Wang X, Chun J, Vilaysane A, Clark S, French G, Bracey NA, Trpkov K, Bonni S, Duff HJ, Beck PL, and Muruve DA. Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium. J Immunol 190: 1239-1249, 2013.
-
(2013)
J Immunol
, vol.190
, pp. 1239-1249
-
-
Wang, W.1
Wang, X.2
Chun, J.3
Vilaysane, A.4
Clark, S.5
French, G.6
Bracey, N.A.7
Trpkov, K.8
Bonni, S.9
Duff, H.J.10
Beck, P.L.11
Muruve, D.A.12
-
138
-
-
76249088729
-
ROS-dependent signaling mechanisms for hypoxic Ca(2 + ) responses in pulmonary artery myocytes
-
Wang YX and Zheng YM. ROS-dependent signaling mechanisms for hypoxic Ca(2 + ) responses in pulmonary artery myocytes. Antioxid Redox Signal 12: 611-623, 2010.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 611-623
-
-
Wang, Y.X.1
Zheng, Y.M.2
-
139
-
-
34250792190
-
Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity
-
Watanabe H, Gaide O, Petrilli V, Martinon F, Contassot E, Roques S, Kummer JA, Tschopp J, and French LE. Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol 127: 1956-1963, 2007.
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1956-1963
-
-
Watanabe, H.1
Gaide, O.2
Petrilli, V.3
Martinon, F.4
Contassot, E.5
Roques, S.6
Kummer, J.A.7
Tschopp, J.8
French, L.E.9
-
140
-
-
79955038882
-
Fatty acid-induced NLRP3- ASC inflammasome activation interferes with insulin signaling
-
Wen H, Gris D, Lei Y, Jha S, Zhang L, Huang MT, Brickey WJ, and Ting JP. Fatty acid-induced NLRP3- ASC inflammasome activation interferes with insulin signaling. Nat Immunol 12: 408-415, 2011.
-
(2011)
Nat Immunol
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
141
-
-
68149100523
-
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasomedependent and -independent pathways
-
Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, and Ting JP. NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasomedependent and -independent pathways. J Immunol 183: 2008-2015, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 2008-2015
-
-
Willingham, S.B.1
Allen, I.C.2
Bergstralh, D.T.3
Brickey, W.J.4
Huang, M.T.5
Taxman, D.J.6
Duncan, J.A.7
Ting, J.P.8
-
142
-
-
84875464393
-
Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury
-
Wu J, Yan Z, Schwartz DE, Yu J, Malik AB, and Hu G. Activation of NLRP3 inflammasome in alveolar macrophages contributes to mechanical stretch-induced lung inflammation and injury. J Immunol 190: 3590-3599, 2013.
-
(2013)
J Immunol
, vol.190
, pp. 3590-3599
-
-
Wu, J.1
Yan, Z.2
Schwartz, D.E.3
Yu, J.4
Malik, A.B.5
Hu, G.6
-
143
-
-
84899564349
-
Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin
-
Xia M, Boini KM, Abais JM, Xu M, Zhang Y, and Li PL. Endothelial NLRP3 inflammasome activation and enhanced neointima formation in mice by adipokine visfatin. Am J Pathol 184: 1617-1628, 2014.
-
(2014)
Am J Pathol
, vol.184
, pp. 1617-1628
-
-
Xia, M.1
Boini, K.M.2
Abais, J.M.3
Xu, M.4
Zhang, Y.5
Li, P.L.6
-
144
-
-
78751475177
-
Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin
-
Xia M, Zhang C, Boini KM, Thacker AM, and Li PL. Membrane raft-lysosome redox signalling platforms in coronary endothelial dysfunction induced by adipokine visfatin. Cardiovasc Res 89: 401-409, 2011.
-
(2011)
Cardiovasc Res
, vol.89
, pp. 401-409
-
-
Xia, M.1
Zhang, C.2
Boini, K.M.3
Thacker, A.M.4
Li, P.L.5
-
145
-
-
84881131862
-
Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic- induced atherosclerosis susceptibility
-
Xiao H, Lu M, Lin TY, Chen Z, Chen G, Wang WC, Marin T, Shentu TP, Wen L, Gongol B, Sun W, Liang X, Chen J, Huang HD, Pedra JH, Johnson DA, and Shyy JY. Sterol regulatory element binding protein 2 activation of NLRP3 inflammasome in endothelium mediates hemodynamic- induced atherosclerosis susceptibility. Circulation 128: 632-642, 2013.
-
(2013)
Circulation
, vol.128
, pp. 632-642
-
-
Xiao, H.1
Lu, M.2
Lin, T.Y.3
Chen, Z.4
Chen, G.5
Wang, W.C.6
Marin, T.7
Shentu, T.P.8
Wen, L.9
Gongol, B.10
Sun, W.11
Liang, X.12
Chen, J.13
Huang, H.D.14
Pedra, J.H.15
Johnson, D.A.16
Shyy, J.Y.17
-
146
-
-
67649831360
-
NLRP3/cryopyrin is necessary for interleukin- 1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
-
Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, Grant EP, Coyle AJ, Misaghi A, Hoffman HM, and Gallo RL. NLRP3/cryopyrin is necessary for interleukin- 1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem 284: 12762-12771, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 12762-12771
-
-
Yamasaki, K.1
Muto, J.2
Taylor, K.R.3
Cogen, A.L.4
Audish, D.5
Bertin, J.6
Grant, E.P.7
Coyle, A.J.8
Misaghi, A.9
Hoffman, H.M.10
Gallo, R.L.11
-
147
-
-
84897575371
-
NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke
-
Yang F, Wang Z, Wei X, Han H, Meng X, Zhang Y, Shi W, Li F, Xin T, Pang Q, and Yi F. NLRP3 deficiency ameliorates neurovascular damage in experimental ischemic stroke. J Cereb Blood Flow Metab 34: 660-667, 2014.
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, pp. 660-667
-
-
Yang, F.1
Wang, Z.2
Wei, X.3
Han, H.4
Meng, X.5
Zhang, Y.6
Shi, W.7
Li, F.8
Xin, T.9
Pang, Q.10
Yi, F.11
-
148
-
-
38349003348
-
Mechanisms of homocysteine-induced glomerular injury and sclerosis
-
Yi F and Li PL. Mechanisms of homocysteine-induced glomerular injury and sclerosis. Am J Nephrol 28: 254-264, 2008.
-
(2008)
Am J Nephrol
, vol.28
, pp. 254-264
-
-
Yi, F.1
Li, P.L.2
-
149
-
-
84878798988
-
Inflammasomes: Sensors of metabolic stresses for vascular inflammation
-
Yin Y, Pastrana JL, Li X, Huang X, Mallilankaraman K, Choi ET, Madesh M, Wang H, and Yang XF. Inflammasomes: sensors of metabolic stresses for vascular inflammation. Front Biosci (Landmark Ed) 18: 638-649, 2013.
-
(2013)
Front Biosci (Landmark Ed)
, vol.18
, pp. 638-649
-
-
Yin, Y.1
Pastrana, J.L.2
Li, X.3
Huang, X.4
Mallilankaraman, K.5
Choi, E.T.6
Madesh, M.7
Wang, H.8
Yang, X.F.9
-
150
-
-
84865820621
-
Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia
-
Zhang C, Boini KM, Xia M, Abais JM, Li X, Liu Q, and Li PL. Activation of Nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia. Hypertension 60: 154-162, 2012.
-
(2012)
Hypertension
, vol.60
, pp. 154-162
-
-
Zhang, C.1
Boini, K.M.2
Xia, M.3
Abais, J.M.4
Li, X.5
Liu, Q.6
Li, P.L.7
-
151
-
-
77950520014
-
Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene
-
Zhang C, Hu JJ, Xia M, Boini KM, Brimson CA, Laperle LA, and Li PL. Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. Free Radic Biol Med 48: 1109-1117, 2010.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1109-1117
-
-
Zhang, C.1
Hu, J.J.2
Xia, M.3
Boini, K.M.4
Brimson, C.A.5
Laperle, L.A.6
Li, P.L.7
-
152
-
-
84934313650
-
Coronary endothelial dysfunction induced by Nlrp3 inflammasome activation during hypercholesterolemia: Beyond inflammation
-
Zhang Y, Li X, Pitzer AL, and Li PL. Coronary endothelial dysfunction induced by Nlrp3 inflammasome activation during hypercholesterolemia: beyond inflammation. FASEB J 28: 851.13, 2014.
-
(2014)
FASEB J
, vol.28
, pp. 85113
-
-
Zhang, Y.1
Li, X.2
Pitzer, A.L.3
Li, P.L.4
-
153
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, and Shao F. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477: 596-600, 2011.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
Liu, L.7
Shao, F.8
-
154
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, and Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 11: 136-140, 2010.
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
155
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, and Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature 469: 221-225, 2011.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|