The inflammasome, autoinflammatory diseases, and gout

Joint Bone Spine

Volumn 74, Issue 6, 2007, Pages 571-576

  Pétrilli, Virginie ^a   Martinon, Fabio ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

IL 1 ; Inflammasome; Monosodium urate; NALP3; Periodic fever

Indexed keywords

COLCHICINE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; URATE;

AUTOINFLAMMATORY DISEASE; DRUG EFFICACY; FEVER; GENE; GENE ACTIVITY; GENE MUTATION; GENETIC DISORDER; GOUT; HUMAN; INFLAMMATION; INNATE IMMUNITY; MONOCYTE; NALP3 GENE; SHORT SURVEY;

AUTOIMMUNE DISEASES; CARRIER PROTEINS; CASPASE 1; FAMILIAL MEDITERRANEAN FEVER; GENETIC PREDISPOSITION TO DISEASE; GOUT; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; MONOCYTES; MUTATION;

EID: 36849095530     PISSN: 1297319X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbspin.2007.04.004     Document Type: Short Survey

References (56)

1. Galon J., Aksentijevich I., McDermott M.F., O'Shea J.J., and Kastner D.L. TNFRSF1A mutations and autoinflammatory syndromes. Curr Opin Immunol 12 (2000) 479-486
2. McDermott M.F., Aksentijevich I., Galon J., McDermott E.M., Ogunkolade B.W., Centola M., et al. Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes. Cell 97 (1999) 133-144
3. McGonagle D., and McDermott M.F. A proposed classification of the immunological diseases. PLoS Med 3 (2006) e297
4. Stojanov S., and Kastner D.L. Familial autoinflammatory diseases: genetics, pathogenesis and treatment. Curr Opin Rheumatol 17 (2005) 586-599
5. Nemunaitis J., Ross M., Meisenberg B., O'Reilly R., Lilleby K., Buckner C.D., et al. Phase I study of recombinant human interleukin-1 beta (rhIL-1 beta) in patients with bone marrow failure. Bone Marrow Transplant 14 (1994) 583-588
6. Nemunaitis J., Appelbaum F.R., Lilleby K., Buhles W.C., Rosenfeld C., Zeigler Z.R., et al. Phase I study of recombinant interleukin-1 beta in patients undergoing autologous bone marrow transplant for acute myelogenous leukemia. Blood 83 (1994) 3473-3479
7. Crown J., Jakubowski A., and Gabrilove J. Interleukin-1: biological effects in human hematopoiesis. Leuk Lymphoma 9 (1993) 433-440
8. McKean D.J., Nilson A., Beck B.N., Giri J., Mizel S.B., and Handwerger B.S. The role of IL 1 in the antigen-specific activation of murine class II-restricted T lymphocyte clones. J Immunol 135 (1985) 3205-3216
9. Tamaru M., Tomura K., Sakamoto S., Tezuka K., Tamatani T., and Narumi S. Interleukin-1beta induces tissue- and cell type-specific expression of adhesion molecules in vivo. Arterioscler Thromb Vasc Biol 18 (1998) 1292-1303
10. Sutton E.T., Norman J.G., Newton C.A., Hellermann G.R., and Richards I.S. Endothelial structural integrity is maintained during endotoxic shock in an interleukin-1 type 1 receptor knockout mouse. Shock 7 (1997) 105-110
11. Furie M.B., and McHugh D.D. Migration of neutrophils across endothelial monolayers is stimulated by treatment of the monolayers with interleukin-1 or tumor necrosis factor-alpha. J Immunol 143 (1989) 3309-3317
12. Dinarello C.A. Interleukin-1beta. Crit Care Med 33 (2005) S460-S462
13. Feng L., Xia Y., Garcia G.E., Hwang D., and Wilson C.B. Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide. J Clin Invest 95 (1995) 1669-1675
14. Pang L., and Knox A.J. Effect of interleukin-1 beta, tumour necrosis factor-alpha and interferon-gamma on the induction of cyclo-oxygenase-2 in cultured human airway smooth muscle cells. Br J Pharmacol 121 (1997) 579-587
15. Dinarello C.A. The IL-1 family and inflammatory diseases. Clin Exp Rheumatol 20 (2002) S1-S13
16. Campbell I.K., Piccoli D.S., Butler D.M., Singleton D.K., and Hamilton J.A. Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue- and urokinase-type plasminogen activator. Biochim Biophys Acta 967 (1988) 183-194
17. Dayer J.M., de Rochemonteix B., Burrus B., Demczuk S., and Dinarello C.A. Human recombinant interleukin 1 stimulates collagenase and prostaglandin E2 production by human synovial cells. J Clin Invest 77 (1986) 645-648
18. Verbruggen G. Chondroprotective drugs in degenerative joint diseases. Rheumatology (Oxford) 45 (2006) 129-138
19. Kostura M.J., Tocci M.J., Limjuco G., Chin J., Cameron P., Hillman A.G., et al. Identification of a monocyte specific pre-interleukin 1 beta convertase activity. Proc Natl Acad Sci U S A 86 (1989) 5227-5231
20. Watanabe H., Gaide O., Petrilli V., Martinon F., Contassot E., Roques S., et al. Activation of the IL-1b-processing inflammasome is involved in contact hypersensitivity. J Invest Dermatol (2007) Epub ahead of print
21. Black R.A., Kronheim S.R., and Sleath P.R. Activation of interleukin-1 beta by a co-induced protease. FEBS Lett 247 (1989) 386-390
22. Thornberry N.A., Bull H.G., Taub D., Wilson K.E., Gimenez-Gallego G., Rosegay A., et al. Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem 266 (1991) 21657-21665
23. Dinarello C.A., and Fantuzzi G. Interleukin-18 and host defense against infection. J Infect Dis 187 (2003) S370-S384
24. Schmitz J., Owyang A., Oldham E., Song Y., Murphy E., McClanahan T.K., et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 23 (2005) 479-490
25. Martinon F., and Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ 14 (2007) 10-22
26. Vasilakos J.P., Ghayur T., Carroll R.T., Giegel D.A., Saunders J.M., Quintal L., et al. IL-1 beta converting enzyme (ICE) is not required for apoptosis induced by lymphokine deprivation in an IL-2-dependent T cell line. J Immunol 155 (1995) 3433-3442
27. Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 80 (1995) 401-411
28. Kuida K., Lippke J.A., Ku G., Harding M.W., Livingston D.J., Su M.S., et al. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267 (1995) 2000-2003
29. Martinon F., Burns K., and Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10 (2002) 417-426
30. Tschopp J., Martinon F., and Burns K. NALPs: a novel protein family involved in inflammation. Nat Rev Mol Cell Biol 4 (2003) 95-104
31. Agostini L., Martinon F., Burns K., McDermott M.F., Hawkins P.N., and Tschopp J. NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 20 (2004) 319-325
32. Sutterwala F.S., Ogura Y., Szczepanik M., Lara-Tejero M., Lichtenberger G.S., Grant E.P., et al. Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1. Immunity 24 (2006) 317-327
33. Mariathasan S., Weiss D.S., Newton K., McBride J., O'Rourke K., Roose-Girma M., et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 40 (2006) 228-232
34. Kanneganti T.D., Ozoren N., Body-Malapel M., Amer A., Park J.H., Franchi L., et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature 440 (2006) 233-236
35. Kastner D.L. Hereditary periodic Fever syndromes. Hematology Am Soc Hematol Educ Program (2005) 74-81
36. Masters S.L., Lobito A.A., Chae J., and Kastner D.L. Recent advances in the molecular pathogenesis of hereditary recurrent fevers. Curr Opin Allergy Clin Immunol 6 (2006) 428-433
37. Prieur A.M., Griscelli C., Lampert F., Truckenbrodt H., Guggenheim M.A., Lovell D.J., et al. A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients. Scand J Rheumatol Suppl 66 (1987) 57-68
38. Feldmann J., Prieur A.M., Quartier P., Berquin P., Certain S., Cortis E., et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet 71 (2002) 198-203
39. Hoffman H.M., Mueller J.L., Broide D.H., Wanderer A.A., and Kolodner R.D. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 29 (2001) 301-305
40. Mikuls T.R., and Saag K.G. New insights into gout epidemiology. Curr Opin Rheumatol 18 (2006) 199-203
41. Wu X.W., Lee C.C., Muzny D.M., and Caskey C.T. Urate oxidase: primary structure and evolutionary implications. Proc Natl Acad Sci U S A 86 (1989) 9412-9416
42. Wu X.W., Muzny D.M., Lee C.C., and Caskey C.T. Two independent mutational events in the loss of urate oxidase during hominoid evolution. J Mol Evol 34 (1992) 78-84
43. Choi H.K., and Curhan G. Gout: epidemiology and lifestyle choices. Curr Opin Rheumatol 17 (2005) 341-345
44. Choi H.K., Atkinson K., Karlson E.W., and Curhan G. Obesity, weight change, hypertension, diuretic use, and risk of gout in men: the health professionals follow-up study. Arch Intern Med 165 (2005) 742-748
45. Terkeltaub R., Zachariae C., Santoro D., Martin J., Peveri P., and Matsushima K. Monocyte-derived neutrophil chemotactic factor/interleukin-8 is a potential mediator of crystal-induced inflammation. Arthritis Rheum 34 (1991) 894-903
46. Hachicha M., Naccache P.H., and McColl S.R. Inflammatory microcrystals differentially regulate the secretion of macrophage inflammatory protein 1 and interleukin 8 by human neutrophils: a possible mechanism of neutrophil recruitment to sites of inflammation in synovitis. J Exp Med 182 (1995) 2019-2025
47. di Giovine F.S., Malawista S.E., Thornton E., and Duff G.W. Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution. J Clin Invest 87 (1991) 1375-1381
48. Niel E., and Scherrmann J.M. Colchicine today. Joint Bone Spine 73 (2006) 672-678
49. Shi Y., Evans J.E., and Rock K.L. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 425 (2003) 516-521
50. Martinon F., Petrilli V., Mayor A., Tardivel A., and Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 440 (2006) 237-241
51. Martinon F., and Glimcher L.H. Gout: new insights into an old disease. J Clin Invest 116 (2006) 2073-2075
52. Chen C.J., Shi Y., Hearn A., Fitzgerald K., Golenbock D., Reed G., et al. MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals. J Clin Invest 116 (2006) 2262-2271
53. Hoffman H.M., Rosengren S., Boyle D.L., Cho J.Y., Nayar J., Mueller J.L., et al. Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist. Lancet 364 (2004) 1779-1785
54. Hawkins P.N., Lachmann H.J., Aganna E., and McDermott M.F. Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra. Arthritis Rheum 50 (2004) 607-612
55. Hawkins P.N., Lachmann H.J., and McDermott M.F. Interleukin-1-receptor antagonist in the Muckle-Wells syndrome. N Engl J Med 348 (2003) 2583-2584
56. So A., De Smedt T., Revaz S., and Tschopp J. A pilot study of IL-1 inhibition by anakinra in acute gout. Arthritis Res Ther 9 (2007) R28