Salmonella pathogenicity island 2-dependent macrophage death is mediated in part by the host cysteine protease caspase-1

Cellular Microbiology

Volumn 3, Issue 12, 2001, Pages 825-837

  Monack, D M ^a   Detweiler, C S ^a   Falkow, S ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYSTEINE PROTEASE CASPASE 1; CYTOKINE; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MEMBRANE PROTEIN; NEUTRALIZING ANTIBODY; PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE MARROW CELL; CELL DEATH; CELL INVASION; CELL LEVEL; CELL VACUOLE; CONTROLLED STUDY; GASTROINTESTINAL TRACT; GENETIC CODE; HOST CELL; INFLAMMATION; MACROPHAGE; MONOCYTE; MOUSE; MUTANT; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FAMILY; PROTEIN SECRETION; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM; STRAIN DIFFERENCE; SYSTEMIC DISEASE;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; CASPASE 1; CELL LINE; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-1; INTERLEUKIN-18; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM; TIME FACTORS; U937 CELLS;

EID: 0035209916     PISSN: 14625814     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1462-5822.2001.00162.x     Document Type: Article

References (55)

1. The apoptotic signaling pathway activated by Toll-like receptor-2
2. Functional caspase-1 is required for Langerhans cell migration and optimal contact sensitization in mice
3. Salmonella maintains the integrity of its intracellular vacuole through the action of SifA
4. A review of human salmonellosis I
5. Salmonella induces macrophage death by caspase-1-dependent necrosis
6. Salmonella spp. are cytotoxic for cultured macrophages
7. Macrophage-dependent induction of the Salmonella pathogenicity island 2 type III secretion system and its role in intracellular survival
8. Type III secretion by Salmonella typhimurium does not require contact with a eukaryotic host
9. Molecular basis of the interaction of Salmonella with the intestinal mucosa
10. Salmonella pathogenicity island 1-independent induction of apoptosis in infected macrophages by Salmonella enterica serotype typhimurium
11. Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death
12. Interleukin-18 and interleukin-1 beta: Two cytokine substrates for ICE (caspase-1)
13. Interleukin-18 regulation of interferon gamma production and cell proliferation as shown in interleukin-1beta-converting enzyme (caspase-1)-deficient mice
14. Functional role of interleukin 1 beta (IL-1 beta) in IL-1 beta-converting enzyme-mediated apoptosis
15. Membrane fusion activity of purified SipB, a Salmonella surface protein essential for mammalian cell invasion
16. Simultaneous identification of bacterial virulence genes by negative selection
17. Functional conservation of the Salmonella and Shigella effectors of entry into epithelial cells
18. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
19. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death
20. Salmonella-induced caspase-2 activation in macrophages. A novel mechanism in pathogen-mediated apoptosis
21. The separation, long-term cultivation, and maturation of the human monocyte
22. Identification and characterization of a Salmonella typhimurium oxygen- regulated gene required for bacterial internalization
23. Salmonellosis: Host immune responses and bacterial virulence determinants
24. OmpR regulates the two-component system SsrA-ssrB in Salmonella pathogenicity island 2
25. The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
26. Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
27. Mice deficient in IL-1β-Converting enzyme are defective in production of mature IL-1b and resistant to endotoxic shock
28. The Salmonella virulence plasmid spv genes are required for cytopathology in human monocyte-derived macrophages
29. Macrophage killing is an essential virulence mechanism of Salmonella typhimurium
30. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis
31. The role of caspases in development, immunity, and apoptotic signal transduction: Lessons from knockout mice
32. Innate immunity: The virtues of a nonclonal system of recognition
33. S-nitrosylation regulates apoptosis
34. Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
35. Salmonella typhimurium invasion induces apoptosis in infected macrophages
36. Salmonella exploits caspase-1 to colonize Peyer's patches in a murine typhoid model
37. Apoptosis and necrosis: Different execution of the same death
38. Identification of a pathogenicity island required for Salmonella survival in host cells
39. Interleukin 18 enhances Fas ligand expression and induces apoptosis in Fas-expressing human myelomonocytic KG-1 cells
40. Canine interleukin-18 induces apoptosis and enhances Fas ligand mRNA expression in a canine carcinoma cell line
41. Building better vaccines: How apoptotic cell death can induce inflammation and activate innate and adaptive immunity
42. Salmonella enterica serovar typhimurium induces cell death in bovine monocyte-derived macrophages by early sipB-dependent and delayed sipB-independent mechanisms
43. Salmonella-induced cell death is not required for enteritis in calves
44. Apoptosis in resolution of inflammation
45. Lipopolysaccharide activates caspase-1 (interleukin-1-converting enzyme) in cultured monocytic and endothelial cells
46. Differential bacterial survival, replication, and apoptosis-inducing ability of Salmonella serovars within human and murine macrophages
47. Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse
48. A novel role for interleukin-18 in human natural killer cell death: High serum levels and low natural killer cell numbers in patients with systemic auto-immune
49. Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone
50. A Salmonella virulence protein that inhibits cellular trafficking
51. Extraintestinal dissemination of Salmonella via CD18-expressing phagocytes
52. Bone marrow-derived macrophages: Development and regulation of differentiation markers by colony-stimulating factor interferons
53. Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells
54. Interleukin 1 is released by murine macrophages during apoptosis induced by Shigella flexneri