NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout

Arthritis and Rheumatism

Volumn 64, Issue 2, 2012, Pages 474-484

  Amaral, Flávio A ^a   Costa, Vivian V ^a   Tavares, Livia D ^a   Sachs, Daniela ^b   Coelho, Fernanda M ^a   Fagundes, Caio T ^a   Soriani, Frederico M ^a   Silveira, Tatiana N ^c   Cunha, Larissa D ^c   Zamboni, Dario S ^c   Quesniaux, Valerie ^d   Peres, Raphael S ^c   Cunha, Thiago M ^c   Cunha, Fernando Q ^c   Ryffel, Bernhard ^d   Souza, Daniele G ^a   Teixeira, Mauro M ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b Natural Resources Institute Universidade de Itajuba   (Brazil)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITÉ D'ORLÉANS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1 RECEPTOR TYPE I; INTERLEUKIN 18 RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; LEUKOTRIENE B4; MYELOID DIFFERENTIATION FACTOR 88; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; GOUT; HYPERNOCICEPTION; IN VIVO STUDY; MACROPHAGE; MALE; MICROVASCULATURE; MOUSE; NEUTROPHIL; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; SYNOVIUM; WILD TYPE;

ANIMALS; CARRIER PROTEINS; CASPASE 1; CYTOKINES; GOUT; HYPERALGESIA; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; LEUKOTRIENE B4; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; NEUTROPHILS; REACTIVE OXYGEN SPECIES; SYNOVIAL MEMBRANE; URIC ACID;

EID: 84856403035     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.33355     Document Type: Article

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