Involvement of xanthine oxidase and hypoxia-inducible factor 1 in Toll-like receptor 7/8-mediated activation of caspase 1 and interleukin-1β

Cellular and Molecular Life Sciences

Volumn 68, Issue 1, 2011, Pages 151-158

  Nicholas, Sally A ^a   Bubnov, Vladimir V ^b   Yasinska, Inna M ^a   Sumbayev, Vadim V ^a  

^a MEDWAY SCHOOL OF PHARMACY   (United Kingdom)

^b ODESSA NATIONAL MEDICAL UNIVERSITY   (Ukraine)

Author keywords

Caspase 1; HIF 1; IL 1 ; Inflammasome; Inflammation; Toll like receptors

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; URIC ACID; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE; MALE; MOUSE; NONHUMAN;

ALLOPURINOL; ANIMALS; CARRIER PROTEINS; CASPASE 1; ENZYME ACTIVATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; IMIDAZOLES; INTERLEUKIN-1BETA; LIGANDS; MALE; MICE; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TUMOR CELLS, CULTURED; XANTHINE OXIDASE;

MUS;

EID: 78650988141     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-010-0450-3     Document Type: Article

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