Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1Β release through pyrophosphates

EMBO Journal

Volumn 28, Issue 14, 2009, Pages 2114-2127

  Pelegrin, Pablo ^a,b   Surprenant, Annmarie ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

Author keywords

Alternative macrophage activation; Caspase 1; Inflammation; NLRP 3 inflammasome; P2X7 receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA ACTIN; CRYOPYRIN; GAMMA INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 4; ION CHANNEL; PURINERGIC P2X7 RECEPTOR; PURINERGIC RECEPTOR; PYROPHOSPHATE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CELL POLARITY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; DYNAMICS; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARRIER PROTEINS; CELL POLARITY; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES; MICE; RECEPTORS, PURINERGIC P2;

EID: 67651172779     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.163     Document Type: Article

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