NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice

Journal of Immunology

Volumn 189, Issue 4, 2012, Pages 2006-2016

  Kovarova, Martina ^a   Hesker, Pamela R ^a,b   Jania, Leigh ^a   Nguyen, MyTrang ^a   Snouwaert, John N ^a   Xiang, Zhidan ^a   Lommatzsch, Stephen E ^a   Huang, Max T ^a   Ting, Jenny P Y ^a,b   Koller, Beverly H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXIN; CELL PROTEIN; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MURAMYL DIPEPTIDE; PROTEIN NLRP1; PROTEIN NLRP1B; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEATH; ENZYME ACTIVATION; GENE; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENE LOCUS; LUNG ALVEOLUS MACROPHAGE; MORBIDITY; MOUSE; NLRP1B GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYROPTOSIS;

ACUTE LUNG INJURY; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CASPASE 1; FLOW CYTOMETRY; INFLAMMASOMES; MACROPHAGES; MICE; MICE, KNOCKOUT;

EID: 84864812784     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1201065     Document Type: Article

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