Caspase-1: Is IL-1 just the tip of the ICEberg?

Cell Death and Disease

Volumn 3, Issue 7, 2012, Pages

  Denes, A ^a   Lopez Castejon, G ^a   Brough, D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

caspase 1; inflammasome; inflammation

Indexed keywords

CANAKINUMAB; CASPASE 3; INFLAMMASOME; INTERLEUKIN 1; INTERLEUKIN 1 CONVERTING ENZYME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PRALNACASAN; PROTEINASE; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS; BRAIN INJURY; BRAIN ISCHEMIA; CELL DEATH; CINCA SYNDROME; CYTOKINE RELEASE; CYTOSKELETON; DISEASE EXACERBATION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME SUBSTRATE; HISTOPATHOLOGY; HUMAN; IMMUNE RESPONSE; IMMUNOREACTIVITY; INHIBITION KINETICS; MACROPHAGE; MOTONEURON; NERVE CELL; NONHUMAN; OLIGOMERIZATION; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; RETINITIS PIGMENTOSA; REVIEW; RHEUMATOID ARTHRITIS; SPINAL CORD INJURY; SPINAL GANGLION; THROMBOEMBOLISM; ANIMAL; ENZYME SPECIFICITY; INFLAMMATION; METABOLISM; PATHOLOGY;

MAMMALIA; VERTEBRATA;

ANIMALS; APOPTOSIS; CASPASE 1; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; NEURONS; SUBSTRATE SPECIFICITY;

EID: 84864883030     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.86     Document Type: Review

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