Fatty acid-induced mitochondrial uncoupling elicits inflammasome- independent IL-1α and sterile vascular inflammation in atherosclerosis

Nature Immunology

Volumn 14, Issue 10, 2013, Pages 1045-1053

  Freigang, Stefan ^a   Ampenberger, Franziska ^a   Weiss, Adrienne ^b   Kanneganti, Thirumala Devi ^c   Iwakura, Yoichiro ^d   Hersberger, Martin ^b   Kopf, Manfred ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FATTY ACID; INFLAMMASOME; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CARDIOVASCULAR DISEASE; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; IMMUNOPATHOLOGY; INNATE IMMUNITY; METABOLIC STRESS; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULITIS;

ANIMALS; ATHEROSCLEROSIS; CALCIUM SIGNALING; DIETARY FATS; FATTY ACIDS; FEMALE; HUMANS; INFLAMMASOMES; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; ION CHANNELS; MACROPHAGES; MICE; MICE, KNOCKOUT; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OLEIC ACID; PLAQUE, ATHEROSCLEROTIC; VASCULITIS;

EID: 84886674980     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2704     Document Type: Article

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