Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia

Free Radical Biology and Medicine

Volumn 67, Issue , 2014, Pages 211-220

  Abais, Justine M ^a   Xia, Min ^a   Li, Guangbi ^a   Gehr, Todd W B ^a   Boini, Krishna M ^a   Li, Pin Lan ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Free radicals; Glomerular sclerosis; Homocysteine; NLRP3 inflammasome; Redox signaling

Indexed keywords

CATALASE; CRYOPYRIN; HYDROGEN PEROXIDE; HYDROXYL RADICAL; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; OXYGEN; PEROXYNITRITE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TEMPOL; AMINE OXIDE; APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; PEROXYNITROUS ACID; PYCARD PROTEIN, MOUSE; SPIN LABELING; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONFOCAL MICROSCOPY; CYTOKINE PRODUCTION; GEL PERMEATION CHROMATOGRAPHY; GLOMERULUS; HYPERHOMOCYSTEINEMIA; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN AGGREGATION; AGONISTS; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; SPIN LABELING; ANIMAL TISSUE; CONTROLLED STUDY; DECOMPOSITION; ENZYME ACTIVATION; GLOMERULOPATHY; PROTEIN LOCALIZATION;

MUS;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CASPASE 1; CATALASE; CELL LINE; CYCLIC N-OXIDES; GENE EXPRESSION; HYDROGEN PEROXIDE; HYPERHOMOCYSTEINEMIA; INFLAMMASOMES; INTERLEUKIN-1BETA; KIDNEY GLOMERULUS; MALE; MICE; MICE, INBRED C57BL; PEROXYNITROUS ACID; PODOCYTES; SPIN LABELS; SUPEROXIDES;

EID: 84888607647     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.10.009     Document Type: Article

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